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Factors associated with stroke in patients with paroxysmal atrial fibrillation beyond CHADS2 score.
CONCLUSIONS: Elevated E velocity, E/E' and SD of tA-SR were associated with occurrence of stroke in patients with PAF even with similar CHAD scores. Increased SD of tA-SR and E/E' were independently associated with stroke in patients with PAF. PMID: 27296157 [PubMed - as supplied by publisher]
Source: Cardiology Journal - June 13, 2016 Category: Cardiology Authors: Kang MK, Han C, Chun KJ, Choi J, Choi S, Cho JR, Lee N Tags: Cardiol J Source Type: research
Post-stroke angiotensin II type 2 receptor activation provides long-term neuroprotection in aged rats
by Douglas M. Bennion, Jacob D. Isenberg, Allison T. Harmel, Kelly DeMars, Alex N. Dang, Chad H. Jones, Megan E. Pignataro, Justin T. Graham, U. Muscha Steckelings, Jon C. Alexander, Marcelo Febo, Eric G. Krause, Annette D. de Kloet, Eduardo Candelario-Jalil, Colin Sumners Activation of the angiotensin II type 2 receptor (AT2R) by administration of Compound 21 (C21), a selective AT2R agonist, induces neuroprotection in models of ischemic stroke in young adult animals. The mechanisms of this neuroprotective action are varied, and may include direct and indirect effec ts of AT2R activation. Our objectives were to assess the...
Source: PLoS One - July 3, 2017 Category: Biomedical Science Authors: Douglas M. Bennion Source Type: research
Acute Neurologic Syndromes Beyond Stroke
This article reviews various disorders with diffusion abnormality that can be commonly seen in the emergency setting.
Source: Neuroimaging Clinics - June 8, 2018 Category: Radiology Authors: Edward K. Sung, Chad Farris, Mohamad Abdalkader, Asim Mian Source Type: research
Identification and Management of Ischemic Stroke in the Postanesthesia Care Unit
This report details the case of a 63-year-old male experiencing a stroke in the immediate postoperative period after total knee arthroplasty. Risk for perioperative stroke is influenced by age, sex, ethnicity, comorbidities, and some medications. The depressed neurocognitive state of patients recovering from anesthesia warrants special consideration for the identification and management of perioperative stroke.
Source: Journal of PeriAnesthesia Nursing - June 12, 2019 Category: Nursing Authors: Lisa O'Driscoll, Chad Moore, Raymond Bonds Tags: Continuing Education Source Type: research
Robotic Exoskeleton Gait Training After Stroke During Inpatient Rehabilitation – Retrospective Findings
To examine functional outcomes of people with stroke in response to robotic exoskeleton gait training (RGT).
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Molly Trammell, Chad Swank, Kara Patterson, Monica Bennett, Christa Ochoa, Librada Callender, Charles Ellis Source Type: research
Adapting An Evidence-Based Healthy Lifestyle Program For People After Stroke
To create an appropriate adaptation of the Diabetes Prevention Program – Group Lifestyle Balance program (DPP-GLB) that meets the unique needs of people post stroke.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Simon Driver, Chad Swank, Ryan Bailey, Katherine Froehlich-Grobe, Evan Elizabeth McShan, Stephanie Calhoun, M. Kaye Kramer Source Type: research
Inclusion of Pulmonary Embolism Response in a Level I Vascular Emergency Program: A Good Fit in a Collaborative, Multidisciplinary System
The value of a systematic approach for assessment and management of life and limb threatening emergencies has been demonstrated by the success of organized trauma centers, stroke centers, and STEMI programs throughout the United States. Recognizing the applicability of a standardized care process to vascular emergencies, Dr. Michael Dalsing of Indiana University –Methodist Hospital led his academic faculty and hospital in the development of a statewide referral and rapid response system for vascular emergencies in 2009.
Source: Annals of Vascular Surgery - December 14, 2016 Category: Surgery Authors: Charles B. Ross, M. Allene Harrison, Michael P. Lunney, Chad E. Miller, Eyal Ben Arie, Chad Case, William L. Ballard, David A. Dean, W. Morris Brown Tags: Abstracts accepted for presentation during the Florida Vascular Society ’s 29th Annual Scientific Sessions Meeting Source Type: research
Relation of Carotid Intima-Media Thickness to Cardiovascular Events in Black Americans (From the Jackson Heart Study)
Although several prospective studies have reported independent relationships between carotid intima-media thickness (CIMT) and risk of incident cardiovascular diseases (CVD) among primarily non-African American (AA) cohorts, the utility of CIMT values for the prediction of incident coronary heart disease and stroke events in blacks remain unclear. At the baseline examination (2000 –2004) of the Jackson Heart Study (JHS), AA adults 21-94 years of age (mean 54) underwent bilateral far-wall CIMT measurement (mean 0.76 mm).
Source: The American Journal of Cardiology - July 31, 2017 Category: Cardiology Authors: Todd C. Villines, Lucy L. Hsu, Chad Blackshear, Cheryl R. Nelson, Michael Griswold Source Type: research
Safety of Moderate Hypothermia With Antegrade Cerebral Perfusion in Total Aortic Arch Replacement
Conclusions In this series, TOTAL with MHCA and ACP can be safely performed with acceptable operative risk. MHCA and ACP represent an effective strategy for TOTAL and may obviate the need for DHCA.
Source: The Annals of Thoracic Surgery - December 10, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research
Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
Atrial fibrillation (AF) is a common cardiac arrhythmia and a major risk factor for stroke, heart failure, and premature death. The pathogenesis of AF remains poorly understood, which contributes to the current lack of highly effective treatments. To understand the genetic variation and biology underlying AF, we undertook a genome-wide association study (GWAS) of 6,337 AF individuals and 61,607 AF-free individuals from Norway, including replication in an additional 30,679 AF individuals and 278,895 AF-free individuals.
Source: The American Journal of Human Genetics - December 28, 2017 Category: Genetics & Stem Cells Authors: Jonas B. Nielsen, Lars G. Fritsche, Wei Zhou, Tanya M. Teslovich, Oddgeir L. Holmen, Stefan Gustafsson, Maiken E. Gabrielsen, Ellen M. Schmidt, Robin Beaumont, Brooke N. Wolford, Maoxuan Lin, Chad M. Brummett, Michael H. Preuss, Lena Refsgaard, Erwin P. B Tags: Article Source Type: research
Contemporary management and outcomes of acute type A aortic dissection: An analysis of the STS adult cardiac surgery database
ConclusionsThese data describe contemporary patient characteristics, operative strategies, and outcomes for AAAD in North America. Mortality and morbidity for AAAD remain high.
Source: Journal of Cardiac Surgery - December 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Teng C. Lee, Zachary Kon, Faisal H. Cheema, Maria V. Grau ‐Sepulveda, Brian Englum, Sunghee Kim, Paramita S. Chaudhuri, Vinod H. Thourani, Gorav Ailawadi, G. Chad Hughes, Matthew L. Williams, J. Matthew Brennan, Lars Svensson, James S. Gammie Tags: ORIGINAL ARTICLE Source Type: research
Neuroprotection by post ‐stroke administration of an oral formulation of angiotensin‐(1–7) in ischaemic stroke
Experimental Physiology,Volume 103, Issue 6, Page 916-923, 1 June 2018.
Source: Experimental Physiology - June 1, 2018 Category: Physiology Authors: Douglas M.Bennion , Chad H.Jones , Lauren L.Donnangelo , Justin T.Graham , Jacob D.Isenberg , Alex N.Dang , VermaliRodriguez , Ruben D. M.Sinisterra , Frederico B.Sousa , Robson A. S.Santos , ColinSumners Source Type: research
Acute Neurologic Syndromes Beyond Stroke: The Role of Emergent MR Imaging
Publication date: Available online 8 June 2018Source: Neuroimaging Clinics of North AmericaAuthor(s): Edward K. Sung, Chad Farris, Mohamad Abdalkader, Asim Mian
Source: Neuroimaging Clinics of North America - July 5, 2018 Category: Radiology Source Type: research
Outcomes of Planned Two-Stage Hybrid Aortic Repair With Dacron-Replaced Proximal Landing Zone
ConclusionsPlanned two-stage HAR with open first-stage proximal aortic replacement, followed by second-stage TEVAR with Dacron-replaced PLZ yields excellent short-term and long-term results, including low rates of reintervention likely due to the long-segment PLZ within the Dacron-replaced aorta. The technique should be considered in patients with even mild (>4.0 cm) ascending aortic dilation in whom HAR is otherwise the preferred treatment option.
Source: The Annals of Thoracic Surgery - August 24, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research
Salvage Coronary Artery Bypass Predicts Increased Mortality during Aortic Root Surgery
ConclusionsCABG during ROOT results in increases in postoperative morbidity or mortality compared with isolated ROOT. Outcomes, however, are influenced by the specific clinical indication. CABG for CAD was associated with similar outcomes compared with isolated ROOT. Patients undergoing unplanned CABG for acute ventricular failure had the worst outcomes, thus underscoring the importance of technical success during coronary reimplantation.
Source: The Annals of Thoracic Surgery - August 29, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research
Risk Prediction Model for Major Adverse Outcome in Proximal Thoracic Aortic Surgery
ConclusionsThe current study identified risk factors for major adverse outcome after proximal thoracic aortic surgery with HCA for degenerative pathology. The proposed simple, accurate model can quantify risk and facilitate physician-patient counseling prior to possible surgical intervention.
Source: The Annals of Thoracic Surgery - November 9, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research
Salvage Coronary Artery Bypass Predicts Increased Mortality During Aortic Root Operation
ConclusionsCABG-R results in increased postoperative morbidity or mortality compared with isolated ROOT. Outcomes, however, are influenced by the specific clinical indication. CABG for coronary artery disease was associated with similar outcomes compared with isolated ROOT. Patients undergoing unplanned CABG for acute ventricular failure had the worst outcomes, thus underscoring the importance of technical success during coronary reimplantation.
Source: The Annals of Thoracic Surgery - November 16, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research
Differences in Statin Utilization and Lipid-Lowering by Race, Ethnicity, and HIV Status in a Real-World Cohort of Persons with Human Immunodeficiency Virus and Uninfected Persons
ConclusionsAmong PWH with statin indication(s), Blacks and Hispanics were less likely than whites to have been prescribed a statin. These racial/ethnic disparities were less pronounced among uninfected persons. There were significant differences in type of statin utilized for PWH compared to uninfected matched controls. Future efforts addressing disparities in CVD prevention among PWH are warranted.
Source: American Heart Journal - December 21, 2018 Category: Cardiology Source Type: research
Differences in statin utilization and lipid lowering by race, ethnicity, and HIV status in a real-world cohort of persons with human immunodeficiency virus and uninfected persons
ConclusionsAmong PWH with statin indication(s), blacks and Hispanics were less likely than whites to have been prescribed a statin. These racial/ethnic disparities were less pronounced among uninfected persons. There were significant differences in type of statin used for PWH compared to uninfected matched controls. Future efforts addressing disparities in CVD prevention among PWH are warranted.
Source: American Heart Journal - January 25, 2019 Category: Cardiology Source Type: research
Risk Prediction Model for Major Adverse Outcome in Proximal Thoracic Aortic Surgery
ConclusionsThe current study identified risk factors for major adverse outcome after proximal thoracic aortic surgery with hypothermic circulatory arrest for degenerative pathology. The proposed simple, accurate model can quantify risk and facilitate physician-patient counseling before possible surgical intervention.
Source: The Annals of Thoracic Surgery - February 20, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research
Neck circumference and cardiovascular outcomes: Insights from the Jackson heart study
ConclusionsIn this large cohort of African American individuals, a larger NC was associated with increased risk for HF hospitalization following adjustment for age and sex, but this risk was not statistically significant after adjusting for other clinical variables. Although NC is not independently associated with increased risk for cardiovascular events, it may offer prognostic information particularly related to HF hospitalization.
Source: American Heart Journal - March 9, 2019 Category: Cardiology Source Type: research
Safety and efficacy of zero fluoroscopy transseptal puncture with different approaches
ConclusionTransseptal puncture can be safely and effectively performed without the need for fluoroscopy.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - November 16, 2019 Category: Cardiology Authors: Tina Baykaner, Ken Quadros, Amit Thosani, Babak Yasmeh, Raman Mitra, Emerson Liu, William Belden, Zhigang Liu, Alex Costea, Chad Brodt, Paul Zei Tags: ELECTROPHYSIOLOGY Source Type: research
The Biggest Loser: Narrative Review of Factors That Influence Weight Loss After Brain Injury
To describe (1) the prevalence of obesity and comorbid conditions in people after brain injury, and (2) the unique physiologic and behavioral barriers faced by people with traumatic brain injury (TBI) and stroke that effect weight loss.
Source: Archives of Physical Medicine and Rehabilitation - November 23, 2019 Category: Rehabilitation Authors: Evan Elizabeth McShan, Stephanie Calhoun, Chad Swank, Simon Driver Tags: Late breaking research poster Source Type: research
Casting a Wide Net: Recruitment Toolkit for Self-Management Studies Involving Individuals With Brain Injury
To discuss the development and use of a toolkit of recruitment strategies when enrolling community-dwelling individuals with brain injury (BI – traumatic and stroke) into self-management interventions.
Source: Archives of Physical Medicine and Rehabilitation - November 23, 2019 Category: Rehabilitation Authors: Stephanie Calhoun, Evan Elizabeth McShan, Megan Reynolds, Chad Swank, Simon Driver Tags: Late breaking research poster Source Type: research
Transcatheter aortic valve replacement for patients with severe bicuspid aortic stenosis
ConclusionsThis initial experience suggests TAVR can be safely performed in patients with BAV achieving similar short-term procedural and clinical outcomes when compared with patients with TAV.Condensed AbstractThe outcomes of 50 patients (8.8%) with bicuspid aortic stenosis (BAV) undergoing TAVR were compared with those of 517 patients (91.2%) with trileaflet aortic valve (TAV) stenosis. Patients with BAV were younger, had higher prevalence of COPD, lower prevalence of CAD, higher BMI and lower STS score. Major complications were similar between the groups, including stroke (2.0% vs. 1.5, P = .567), 30-day all-c...
Source: American Heart Journal - February 9, 2020 Category: Cardiology Source Type: research