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Total 797 results found since Jan 2013.

Study protocol for development and validation of a single tool to assess risks of stroke, diabetes mellitus, myocardial infarction and dementia: DemNCD-Risk
Introduction Current efforts to reduce dementia focus on prevention and risk reduction by targeting modifiable risk factors. As dementia and cardiometabolic non-communicable diseases (NCDs) share risk factors, a single risk-estimating tool for dementia and multiple NCDs could be cost-effective and facilitate concurrent assessments as compared with a conventional single approach. The aim of this study is to develop and validate a new risk tool that estimates an individual’s risk of developing dementia and other NCDs including diabetes mellitus, stroke and myocardial infarction. Once validated, it could be used by the ...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Kootar, S., Huque, M. H., Kiely, K. M., Anderson, C. S., Jorm, L., Kivipelto, M., Lautenschlager, N. T., Matthews, F., Shaw, J. E., Whitmer, R. A., Peters, R., Anstey, K. J. Tags: Open access, Public health Source Type: research

Prevalence of atrial septal defects and patent foramen ovale in a cohort of sudden cardiac death patients undergoing autopsy
CONCLUSIONS: The combined rate of PFO and ASD in a cohort of 517 patients undergoing autopsy was 7.9 %. None of these patients had experienced a cerebrovascular accident. This rate of PFOs appears lower than earlier reports and raises the possibility that the relative risk of an associated stroke could be higher than previously estimated.PMID:37734655 | DOI:10.1016/j.jjcc.2023.09.006
Source: Journal of Cardiology - September 21, 2023 Category: Cardiology Authors: Louise Fahy Stephanie Rowe Ziad Nehme Dion Stub Dominica Zentner Paul James Andreas Pflaumer Vanessa Connell Christopher Semsarian Jodie Ingles Andre La Gerche Elizabeth D Paratz Source Type: research

Stroke Riskometer Application (SRA ™) influence on lifestyle changes of home bound familial Malaysian stroke caregivers: a randomised controlled trial in a primary care based longer term stroke care facility
CONCLUSION: SRA™ is a useful tool for familial stroke caregivers to make lifestyle changes, although it did not reduce personal or relative stroke risk after 3 months usage.TRIAL REGISTRATION: No: ACTRN12618002050235 (Registration Date: 21st December 2018).PMID:37684626 | PMC:PMC10486033 | DOI:10.1186/s12875-023-02138-x
Source: Primary Care - September 8, 2023 Category: Primary Care Authors: Radhiyah Hussin Aznida Firzah Abdul Aziz Mohd Fairuz Ali Ezura Madiana Md Monoto H S Arvinder-Singh Alabed Ali Ahmed Alabed Wan Asyraf Wan Zaidi Norlinah Mohamed Ibrahim FRCPE Source Type: research

Should beetles be named after Adolf Hitler?
In 1934, a German paleontologist named a giant flying insect from the Carboniferous period Rochlingia hitleri , after Adolf Hitler, who had just taken power in Germany, and Hermann Röchling, an anti-semitic steel manufacturer and member of the Nazi Party. Three years later, an Austrian amateur entomologist named a brown, eyeless beetle from Slovenian caves Anophthalmus hitleri because he admired Hitler. In recent years, neo-Nazis have reportedly paid thousands for specimens, pushing the beetle toward extinction . Some researchers have argued for years that A. hitleri and other spec...
Source: Science of Aging Knowledge Environment - September 5, 2023 Category: Geriatrics Source Type: research

Trends in mental health inequalities for people with disability, Australia 2003 to 2020
CONCLUSION: This paper confirms that people with disability experience worse mental health than people without disability. We add to previous findings by demonstrating that disability-related inequalities in mental health have been sustained for a long period and are worsening in some subpopulations.PMID:37606227 | DOI:10.1177/00048674231193881
Source: The Australian and New Zealand Journal of Psychiatry - August 22, 2023 Category: Psychiatry Authors: Glenda M Bishop Anne Marie Kavanagh George Disney Zoe Aitken Source Type: research

Consensus statement for the management of incidentally found brain white matter hyperintensities in general medical practice
Med J Aust. 2023 Aug 21. doi: 10.5694/mja2.52079. Online ahead of print.ABSTRACTINTRODUCTION: There is a paradigm shift in our understanding of white matter hyperintensities (WMH) found on brain imaging. They were once thought to be a normal phenomenon of ageing and, therefore, warranted no further investigation. However, evidence now suggests these lesions are markers of poor brain and cardiovascular health, portending an increased risk of stroke, cognitive decline, depression and death. Nevertheless, no specific guidelines exist for the management of incidentally found WMH for general medical practitioners and other clin...
Source: Medical Journal of Australia - August 21, 2023 Category: General Medicine Authors: Thomas P Ottavi Elizabeth Pepper Grant Bateman Mark Fiorentino Amy Brodtmann Source Type: research

Development and validation of a dementia risk score in the UK Biobank and Whitehall II cohorts
Background Current dementia risk scores have had limited success in consistently identifying at-risk individuals across different ages and geographical locations. Objective We aimed to develop and validate a novel dementia risk score for a midlife UK population, using two cohorts: the UK Biobank, and UK Whitehall II study. Methods We divided the UK Biobank cohort into a training (n=176 611, 80%) and test sample (n=44 151, 20%) and used the Whitehall II cohort (n=2934) for external validation. We used the Cox LASSO regression to select the strongest predictors of incident dementia from 28 candidate predictors and then dev...
Source: Evidence-Based Mental Health - August 21, 2023 Category: Psychiatry & Psychology Authors: Anatürk, M., Patel, R., Ebmeier, K. P., Georgiopoulos, G., Newby, D., Topiwala, A., de Lange, A.-M. G., Cole, J. H., Jansen, M. G., Singh-Manoux, A., Kivimäki, M., Suri, S. Tags: Open access, Press releases Old age psychiatry Source Type: research

Interventions for the uptake of evidence-based recommendations in acute stroke settings
CONCLUSIONS: We are uncertain whether a multifaceted implementation intervention compared to no intervention improves adherence to evidence-based recommendations in acute stroke settings, because the certainty of evidence is very low.PMID:37565934 | PMC:PMC10416310 | DOI:10.1002/14651858.CD012520.pub2
Source: Cochrane Database of Systematic Reviews - August 11, 2023 Category: General Medicine Authors: Elizabeth A Lynch Lemma N Bulto Heilok Cheng Louise Craig Julie A Luker Kathleen L Bagot Tharshanah Thayabaranathan Heidi Janssen Elizabeth McInnes Sandy Middleton Dominique A Cadilhac Source Type: research

Effect of Concomitant Cardiac Arrest on Outcomes in Patients With Acute Coronary Syndrome-Related Cardiogenic Shock
Patients with acute coronary syndrome (ACS)-related cardiogenic shock (CS) with or without concomitant CA may have disparate prognoses. We compared clinical characteristics and outcomes of patients with CS secondary to ACS with and without cardiac arrest (CA). Between 2014 and 2020, 1,573 patients with ACS-related CS with or without CA who underwent percutaneous coronary intervention enrolled in a multicenter Australian registry were analyzed. Primary outcome was 30-day major adverse cardiovascular and cerebrovascular events (MACCE) (composite of mortality, myocardial infarction, stent thrombosis, target vessel revascularization and stroke).
Source: The American Journal of Cardiology - August 2, 2023 Category: Cardiology Authors: Wayne C. Zheng, Diem Dinh, Samer Noaman, Jason E. Bloom, Riley J. Batchelor, Jeffrey Lefkovits, Angela L. Brennan, Christopher M. Reid, Omar Al-Mukhtar, James A. Shaw, Dion Stub, Yang Yang, Craig French, David M. Kaye, Nicholas Cox, William Chan Source Type: research

Short-term DAPT after coronary stenting has similar ischemic and bleeding outcomes as long-term DAPT: a 5-year population-based cohort study
ConclusionThere is no significant difference in both bleeding and ischemic outcomes in long-term DAPT as compared to short-term DAPT for first- and second-generation drug-eluting stents in a real-world population.
Source: Irish Journal of Medical Science - August 1, 2023 Category: General Medicine Source Type: research

E-098 Initial experience with the pipeline vantage flow diverter - vantage one study: six-month results, technical and clinical consideration
ConclusionThe new PVED reveals improved device visibility, ease of delivery and repositioning with precise distal opening in comparison to previous PED generations. Initial results demonstrate overall good device performance, safety profile and effectiveness. The implant requires a modified deployment technique for successful vessel wall apposition of the proximal stent as opposed to the previous generations of PED.ReferencesLylyk I, Scrivano E, Lundquist J, Ferrario A, Bleise C, Perez N, Lylyk PN, Viso R, Nella-Castro R, Lylyk P. Pipeline embolization devices for the treatment of intracranial aneurysms, single-center regi...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: de Viliers, L., Carraro do Nascimento, V., Domitrovic, L., Rice, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

These ants are ballooning with microbe-killing honey
Buried deep underneath the red, sunbaked soil of Australia’s deserts are hidden treasure troves of honey. It’s not the delicacy produced by bees, but rather the only type of honey made by ants. It’s also, a new study confirms, a potentially powerful medicine with antimicrobial properties. Australia’s Indigenous peoples have long used honey from honeypot ants ( Camponotus inflatus ) to treat a variety of maladies, from sore throats to infected wounds. Now, Western scientists are finally getting up to speed. In a study published today in PeerJ , researchers show that the honeypot ant’s honey has...
Source: Science of Aging Knowledge Environment - July 26, 2023 Category: Geriatrics Source Type: research