Query: stroke

Filtered By:
Countries: Australia Health

This page shows you your search results in order of date.

Order by Relevance | Date

Total 285 results found since Jan 2013.

Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial
Publication date: March 2020Source: The Lancet Neurology, Volume 19, Issue 3Author(s): Hugues Chabriat, Claudio L Bassetti, Ute Marx, Marie-Laure Audoli-Inthavong, Aurore Sors, Estelle Lambert, Marine Wattez, Dirk M Hermann, Katharina ALTHAUS, Sergi AMARO, Hee-Joon BAE, Zbigniew BAK, Leonardo BARBARINI, Pietro BASSI, Rodrigo BAZAN, Daniel BERECZKI, Tomasz BERKOWICZ, Joerg BERROUSCHOT, Dylan BLACQUIERE, Waldemar BROLASummaryBackgroundS44819, a selective GABAA α5 receptor antagonist, reduces tonic post-ischaemic inhibition of the peri-infarct cortex. S44819 improved stroke recovery in rodents and increased cortical excitabi...
Source: The Lancet Neurology - February 19, 2020 Category: Neurology Source Type: research

Spirituality and resilience among family  caregivers of survivors of stroke: A scoping review.
CONCLUSIONS: Spirituality and resilience following stroke are essential factors in caregiver adjustment following stroke. Further research with a focus on causality and the link between spirituality, resilience and adjustment in this population is needed. PMID: 32039873 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - February 11, 2020 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Differences in stroke risk and cardiovascular mortality for Aboriginal and other Australian patients with atrial fibrillation.
CONCLUSION: Stroke risk and cardiovascular mortality are markedly higher for Aboriginal than non-Aboriginal patients with atrial fibrillation, particularly for patients under 60. Strategies for providing evidence-based therapies and cardiovascular prevention to Aboriginal people with atrial fibrillation must be improved. PMID: 32030754 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - February 8, 2020 Category: General Medicine Tags: Med J Aust Source Type: research

The Tasmanian Atrial Fibrillation Study (TAFS): Differences in Stroke Prevention According to Sex.
Conclusion and Relevance: Female patients with a high stroke risk were less likely to receive guideline-recommended treatment. This study provides new information on prescribing trends within the Australian setting and highlights the opportunity to improve the management of female patients with AF and 1 or more additional stroke risk factors. PMID: 32019321 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - February 4, 2020 Category: Drugs & Pharmacology Authors: Pilcher SM, Alamneh EA, Chalmers L, Bereznicki LR Tags: Ann Pharmacother Source Type: research

Featured Review: Treating depression after stroke
Depression is common after stroke yet often is not detected or inadequately treated.Review authors from Australia, Canada, Taiwan and the UK asked, " Do pharmacological treatments, non ‐invasive brain stimulation, psychological treatments, or combination treatments reduce the proportion of people with depression or the extent of depressive symptoms after stroke? "The authors included trials that reported on the use of pharmacological, non ‐invasive brain stimulation, psychological, and combination therapy interventions to treat depression after stroke. Mean age of people included in the trials ranged from 54 to 78 year...
Source: Cochrane News and Events - January 28, 2020 Category: Information Technology Authors: Katie Abbotts Source Type: news

Challenges of delivering evidence-based stroke services for rural areas in Australia.
CONCLUSION: Evidence-based stroke care, aligned with current national standards is the key to providing adequate stroke services in rural Australia. Improved health service resourcing and better utilisation of currently available resources are options for achieving elements of evidence-based stroke care. IMPLICATIONS FOR PUBLIC HEALTH: Availability of adequate services for stroke patients directly impacts public health as it determines health outcomes for these patients. Indirect implications for public health include the effects on health professionals and the general public. PMID: 31990135 [PubMed - as supplied by publisher]
Source: The Australian Journal of Rural Health - January 28, 2020 Category: Rural Health Authors: Prior SJ, Reeves NS, Campbell SJ Tags: Aust J Rural Health Source Type: research

Reducing Tongue Fat Could Improve Sleep Apnea, Study Says
This study shows reducing excess fat in general can reduce tongue size,” said Dr. Raj Dasgupta, a sleep specialist at Keck Medicine at the University of Southern California, who was not involved in the study. In the new paper, the researchers used MRI imaging to measure the effect on upper airways of a 10% weight loss in 67 obese patients. The images showed reducing tongue fat was the primary reason overall sleep apnea scores improved by 31%. “In fact, the more tongue fat you lost, the more your apnea improved,” said Schwab, who is the co-director of the Penn Sleep Center at Penn Medicine. Costs of sleep ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 10, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated CBSN Boston CNN Source Type: news

Occupational engagement following mild stroke in the Australian context using the occupational gaps questionnaire.
Conclusions and significance: The English version of the OGQ was found to be a feasible instrument for identifying occupational gaps following mild stroke and may be suitable to support research and clinical practice with this population. PMID: 31906780 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - January 8, 2020 Category: Occupational Health Tags: Scand J Occup Ther Source Type: research

Multiple Peri-Operative Complications are Associated with Reduced Long Term Amputation Free Survival Following Revascularisation for Lower Limb Peripheral Artery Disease: A Population Based Linked Data Study.
CONCLUSION: Multiple complications after surgery for lower limb PAD carried a compounding risk of reduced long term amputation free survival. Patients experiencing at least one complication form a high risk group that requires increased attention to prevent the potential development of further complications. PMID: 31879146 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - December 23, 2019 Category: Surgery Authors: Aitken SJ, Randall DA, Noguchi N, Blyth FM, Naganathan V Tags: Eur J Vasc Endovasc Surg Source Type: research

Effect of obstructive sleep apnoea and its treatment with continuous positive airway pressure on the prevalence of cardiovascular events in patients with acute coronary syndrome (ISAACC study): a randomised controlled trial
This study is registered with Clinicaltrials.gov, NCT01335087 and is now closed.FindingsBetween April 25, 2011, and Feb 2, 2018, a total of 2834 patients with ACS had respiratory polygraphy, of whom 2551 (90·01%) were recruited. 1264 (49·55%) patients had OSA and were randomly assigned to the CPAP group (n=633) or the UC group (n=631). 1287 (50·45%) patients did not have OSA, of whom 603 (46·85%) were randomly assigned to the reference group. Patients were followed up for a median of 3·35 years (IQR 1·50–5·31). The prevalence of cardiovascular events was similar in the CPAP and UC groups (98 events [16%] vs 108 ev...
Source: The Lancet Respiratory Medicine - December 14, 2019 Category: Respiratory Medicine Source Type: research

Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium
Publication date: Available online 3 December 2019Source: The LancetAuthor(s): Fabian J Brunner, Christoph Waldeyer, Francisco Ojeda, Veikko Salomaa, Frank Kee, Susana Sans, Barbara Thorand, Simona Giampaoli, Paolo Brambilla, Hugh Tunstall-Pedoe, Marie Moitry, Licia Iacoviello, Giovanni Veronesi, Guido Grassi, Ellisiv B Mathiesen, Stefan Söderberg, Allan Linneberg, Hermann Brenner, Philippe Amouyel, Jean FerrièresSummaryBackgroundThe relevance of blood lipid concentrations to long-term incidence of cardiovascular disease and the relevance of lipid-lowering therapy for cardiovascular disease outcomes is unclear. We invest...
Source: The Lancet - December 5, 2019 Category: General Medicine Source Type: research

Why You Should Start Thinking About Your Cholesterol Earlier
High cholesterol is known to be one of the primary risk factors for heart disease, since it can contribute to plaque buildup in the arteries. But even though the U.S. Centers for Disease Control and Prevention recommends regular cholesterol testing starting around age 20, many Americans don’t give cholesterol—or heart disease, for that matter—much thought until later in life. A new modeling study published in the Lancet gives extra reason not to put off cholesterol screening and treatment. It confirms that high blood levels of “bad” (or non-HDL) cholesterol are associated with a greater risk o...
Source: TIME: Health - December 4, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Research Source Type: news

Should This Patient Be Screened for Atrial Fibrillation?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
Discussion From Beth Israel Deaconess Medical Center. Ann Intern Med. 2019 Dec 03;171(11):828-836 Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Abstract Atrial fibrillation (AFib) is the most common type of cardiac arrhythmia, affecting 2.7 million to 6.1 million persons in the United States. Although some persons with AFib have no symptoms, others do. For those without symptoms, AFib may be detected by 12-lead electrocardiogram (ECG), single-lead monitors (such as ambulatory blood pressure monitors and pulse oximeters), or consumer devices (such as wearable monitors and smartphones). Pulse pa...
Source: Annals of Internal Medicine - December 3, 2019 Category: Internal Medicine Authors: Burns RB, Zimetbaum P, Lubitz SA, Smetana GW Tags: Ann Intern Med Source Type: research

Addressing inequity in acute stroke care requires attention to each component of regional workflow.
Authors: Watson T, Tiu J, Clissold B PMID: 31785010 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - December 2, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Quality of Warfarin Anticoagulation in Indigenous and Non-Indigenous Australians With Atrial Fibrillation
Studies have shown that suboptimal anticoagulation quality, as measured by time in therapeutic range (TTR), affects a significant percentage of patients with atrial fibrillation (AF). However, TTR has not been previously characterised in Indigenous Australians who experience a greater burden of AF and stroke.
Source: Heart, Lung and Circulation - November 28, 2019 Category: Cardiology Authors: Mau T. Nguyen, Celine Gallagher, Bradley M. Pitman, Mehrdad Emami, Kadhim Kadhim, Jeroen M. Hendriks, Melissa E. Middeldorp, Kurt C. Roberts-Thomson, Rajiv Mahajan, Dennis H. Lau, Prashanthan Sanders, Christopher X. Wong Tags: Original Article Source Type: research

Quality of Warfarin Anticoagulation in  Indigenous and Non-Indigenous Australians With Atrial Fibrillation
Studies have shown that suboptimal anticoagulation quality, as measured by time in therapeutic range (TTR), affects a significant percentage of patients with atrial fibrillation (AF). However, TTR has not been previously characterised in Indigenous Australians who experience a greater burden of AF and stroke.
Source: Heart, Lung and Circulation - November 28, 2019 Category: Cardiology Authors: Mau T. Nguyen, Celine Gallagher, Bradley M. Pitman, Mehrdad Emami, Kadhim Kadhim, Jeroen M. Hendriks, Melissa E. Middeldorp, Kurt C. Roberts-Thomson, Rajiv Mahajan, Dennis H. Lau, Prashanthan Sanders, Christopher X. Wong Tags: Original Article Source Type: research

This Under-Utilized Drug Is Actually Critical for Treatment-Resistant Depression
Many people with clinical depression have tried an array of medication and still feel sick. Maybe they’ve tried different selective serotonin reuptake inhibitors (SSRIs) or selective norepinephrine reuptake inhibitors (SNRIs). Maybe they’ve taken these antidepressants along with an antipsychotic (a common strategy to boost effectiveness). Either way, the lack of improvement can make individuals feel even more hopeless and fear the darkness will never lift. If this sounds all-too familiar, you’re definitely not alone. In fact, up to 30 percent of people with depression don’t respond to the first few antidepressants ...
Source: Psych Central - November 27, 2019 Category: Psychiatry Authors: Margarita Tartakovsky, M.S. Tags: Antidepressants Depression Disorders ECT General Medications Treatment Atypical Depression difficult to treat depression Managing Depression MAOIs medication for depression Monoamine Oxidase Inhibitors Severe Depression Treatin Source Type: news

Advances in stroke medicine.
Authors: Cheng S, Richards T PMID: 31763695 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - November 26, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
A randomized, prospective study from the United Kingdom and Australia was conducted between February 24, 2006 and June 17, 2013.
Source: Journal of Vascular Surgery - November 22, 2019 Category: Surgery Authors: H.S. Markus, C. Levi, A. King, J. Madigan, J. Norris, Cervical Artery Dissection in Stroke Study (CADISS) Investigators. Tags: There is no difference in treatment of carotid or vertebral artery dissection with antiplatelet vs anticoagulant therapy Source Type: research

Arterial Stiffness and Indices of Left Ventricular Diastolic Dysfunction in Patients with Embolic Stroke of Undetermined Etiology.
Conclusions: Increased arterial stiffness and indices of diastolic dysfunction as well as a higher NT-proBNP level are significantly associated with ESUS. These parameters require further scrutiny over time to understand their impact on the development of symptomatic heart failure. The ClinicalTrials.gov identifier is NCT03377465. PMID: 31612072 [PubMed - in process]
Source: Disease Markers - October 17, 2019 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

Device closure for patent foramen ovale in patients with cryptogenic stroke: a paradigm in evidence.
Authors: Ha FJ, Adams H, Palmer S PMID: 31523821 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - September 17, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia).
Abstract Utstein-style reporting templates provide a structured framework with which to compare systems of care for cardiac arrest. The 2004 Utstein reporting template encompassed both out-of-hospital and in-hospital cardiac arrest. A 2015 update of the Utstein template focused on out-of-hospital cardiac arrest, which makes this update of the in-hospital template timely. Representatives of the International Liaison Committee on Resuscitation developed an updated in-hospital Utstein reporting template iteratively by meeting face-to-face, by teleconference, and by online surveys between 2013 and 2018. Data elements ...
Source: Circulation - September 16, 2019 Category: Cardiology Authors: Nolan JP, Berg RA, Andersen LW, Bhanji F, Chan PS, Donnino MW, Lim SH, Ma MH, Nadkarni VM, Starks MA, Perkins GD, Morley PT, Soar J, Utstein Collaborators Tags: Circulation Source Type: research

Are we there yet? Exploring the journey to quality stroke care for Aboriginal and Torres Strait Islander peoples in rural and remote Queensland.
CONCLUSION: An integrated patient centred model of care that spans the care continuum and places value on an extended role for the Aboriginal and Torres Strait Islander health worker workforce is indicated, as is an increased utilisation of allied health and specialist follow-up close to home. PMID: 31487467 [PubMed - in process]
Source: Rural and Remote Health - September 7, 2019 Category: Rural Health Tags: Rural Remote Health Source Type: research

Inclusion of a care bundle for fever, hyperglycaemia and swallow management in a National Audit for acute stroke: evidence of upscale and spread
In the Quality in Acute Stroke Care (QASC) trial undertaken in stroke units (SUs) located in New South Wales (NSW), Australia (2005 –2010), facilitated implementation of a nurse-led care bundle to manage fever,...
Source: Implementation Science - September 2, 2019 Category: Health Management Authors: Tara Purvis, Sandy Middleton, Louise E. Craig, Monique F. Kilkenny, Simeon Dale, Kelvin Hill, Catherine D ’Este and Dominique A. Cadilhac Tags: Research Source Type: research

Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depressive Symptom Scores.
Conclusions: We provide evidence that fALFF is sensitive to changes in poststroke depressive symptom severity and implicates frontostriatal and cerebellar regions, consistent with previous studies. The use of multiband analysis could be an effective method to examine neural correlates of depression after stroke. The START-PrePARE trial is registered with the Australian New Zealand Clinical Trial Registry, number ACTRN12610000987066. PMID: 31467520 [PubMed - in process]
Source: Neural Plasticity - September 1, 2019 Category: Neurology Authors: Goodin P, Lamp G, Vidyasagar R, Connelly A, Rose S, Campbell BCV, Tse T, Ma H, Howells D, Hankey GJ, Davis S, Donnan G, Carey LM Tags: Neural Plast Source Type: research

Air retrieval for clot retrieval; time-metrics and outcomes of stroke patients from rural and remote regions air-transported for mechanical thrombectomy at a state stroke unit
ConclusionWith the availability of an efficient aeromedical retrieval service, LVO stroke patients in rural and remote regions can achieve excellent outcomes following transfer to a high volume thrombectomy unit, even if distances involved are very large.
Source: Journal of Clinical Neuroscience - August 21, 2019 Category: Neuroscience Source Type: research

Googling Location for Operating Base of Mobile Stroke Unit in Metropolitan Sydney
Conclusions: Any of the ECR capable hospital can serve as a hub for MSU. We provide a method to identify the hub based on location of suburbs less well served by other hospital.
Source: Frontiers in Neurology - August 6, 2019 Category: Neurology Source Type: research

The lived experience of supporting people with mild stroke.
Conclusions and Significance: Whilst spouses generally return to their daily routines after a family members' mild stroke, some will experience increased time pressures and occupational disruptions. Health providers should prepare spouses for behavioral and emotional changes in people with mild stroke. PMID: 31264497 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - July 4, 2019 Category: Occupational Health Tags: Scand J Occup Ther Source Type: research

Application of Strategic Transport Model and Google Maps to Develop Better Clot Retrieval Stroke Service
Discussion: The results from strategic transport model are similar to those from Google Maps. In this paper we illustrate how this method can be applied in designing and forecast stroke service model in different cities in Australia and around the world.
Source: Frontiers in Neurology - June 28, 2019 Category: Neurology Source Type: research

Comparison of Echocardiographic Parameters of Left Atrial and Ventricular Function between Young Stroke vs Lone Atrial Fibrillation vs Healthy Controls
Background: Stroke is one of Australia's leading causes of morbidity and mortality with a significant percentage classified as cryptogenic. The nature and aetiology of cryptogenic stroke remains elusive, with a proportion believed to be cardio-embolic secondary to subclinical paroxysmal atrial fibrillation (AF). We aim to gain mechanistic insights into the pathophysiology of cryptogenic stroke in the young by comparing cardiac structural and functional differences in patients with young stroke, lone AF and healthy controls.
Source: Heart, Lung and Circulation - June 24, 2019 Category: Cardiology Authors: A. Bhat, S. Khanna, H. Chen, G. Gan, R. MacIntyre, T. Tan Tags: 254 Source Type: research

Is Incorrect Anti-Coagulation Dosing Contributing to Ischaemic Stroke Burden? A Retrospective Single-Centre Study from Regional New South Wales, Australia
Background: Atrial fibrillation (AF) contributes to 30% of ischaemic stroke presentations. Low doses of anti-coagulants are often prescribed to prevent stroke but ameliorate bleeding risk.
Source: Heart, Lung and Circulation - June 24, 2019 Category: Cardiology Authors: P. Bamford, M. Ray, S. Cheruvu, M. Parkinson, C. Said, J. Trappel, J. Rogers Tags: 195 Source Type: research

Help-seeking and people with aphasia who have mood problems after stroke: perspectives of speech-language pathologists.
CONCLUSIONS & IMPLICATIONS: SLPs report both universal barriers to help-seeking and those specific to their clients with aphasia and attempts to overcome these; however, there appears to be a dearth of accessible mental health services for people with aphasia known to SLPs, including psychological/counselling professionals who are skilled in communicating with people with aphasia. Health professionals working within and across post-stroke and mental health services should recognize that people with post-stroke aphasia are susceptible to a decline in mental health, are amenable to formal (and tailored) psychological sup...
Source: International Journal of Language and Communication Disorders - June 17, 2019 Category: Speech-Language Pathology Authors: Ryan B, Bohan J, Kneebone I Tags: Int J Lang Commun Disord Source Type: research

Stroke Risk Factors and Outcomes in Indigenous Verse Non-Indigenous Australians
Background: Stroke risk factors are well known, but there is little data on the prevalence of stroke risk factors in Indigenous Australian cohorts. We aim to assess the risk factors and the outcomes after stroke and compare these in Indigenous and non-Indigenous Australians presenting with acute strokes to the Wagga Wagga Rural Referral Hospital.
Source: Heart, Lung and Circulation - May 25, 2019 Category: Cardiology Authors: Angela Dos Santos, Katherine Mohr, Martin Jude, Neil Simon, Candice Delcourt Tags: P20 Source Type: research

Stroke Incidence and Outcomes in Indigenous Australians
We present the first prospective population-based pilot study of stroke incidence and outcomes in Indigenous Australians.
Source: Heart, Lung and Circulation - May 25, 2019 Category: Cardiology Authors: Angela Dos Santos, Anna Balabanski, Tim Kleinig, Amanda Thrift, Alex Brown, Judith Katzenellenbogen, Edmung Cheong Tags: P19 Source Type: research

Evaluating Personal Stroke Narratives from Bilingual Greek-English Immigrants with Aphasia
Conclusion: The results have implications for policy-makers providing health and welfare services to ageing immigrant populations. The findings are also relevant to other countries that have large immigrant populations of stroke survivors.Folia Phoniatr Logop 2019;71:101 –115
Source: Folia Phoniatrica et Logopaedica - May 14, 2019 Category: Speech-Language Pathology Source Type: research

Advances in stroke medicine.
Authors: Campbell BC Abstract In recent years, reperfusion therapies such as intravenous thrombolysis and endovascular thrombectomy for ischaemic stroke have dramatically reduced disability and revolutionised stroke management. Thrombolysis with alteplase is effective when administered to patients with potentially disabling stroke, who are not at high risk of bleeding, within 4.5 hours of the time the patient was last known to be well. Emerging evidence suggests that other thrombolytics such as tenecteplase may be even more effective. Treatment may be possible beyond 4.5 hours in patients selected using brain imagi...
Source: Medical Journal of Australia - May 6, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Using Dental Pulp Stem Cells for Stroke Therapy
Conclusion and Future Perspectives Stem cell-based therapy is a promising alternative for stroke treatment. While stem cells from different sources, including induced PSC, ESC, MSC, and NSC, have been investigated, using NSC and enhancing the natural mechanisms is most appropriate for brain repair. In preclinical models of stroke, stem cell transplantation has led to positive outcomes through a variety of cellular and molecular mechanisms, many being mediated by the array of beneficial factors produced by the cells. Recent advances in cellular reprogramming have provided alternative sources of NSC to be investigated, allo...
Source: Frontiers in Neurology - April 29, 2019 Category: Neurology Source Type: research

Pre-hospital Triage of Acute Ischemic Stroke Patients —Importance of Considering More Than Two Transport Options
Conclusion: Pre-hospital triage algorithms for AIS patients that only take into account the nearest CSC and the nearest PSC as transport destinations may be unable to identify the optimal transport destination for a significant proportion of patients. Introduction Background International guidelines recommend early administration of intravenous thrombolysis for eligible patients with acute ischemic stroke (AIS); in addition, patients with proximal large vessel occlusion (LVO) should receive mechanical thrombectomy (MT) as quickly as possible (1). As the clinical benefit of both thrombolysis (2–4) and MT (5&#...
Source: Frontiers in Neurology - April 26, 2019 Category: Neurology Source Type: research

Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis
Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice. Introduction Shoulder-hand syndrome (SHS) is a common condition among people who have had a stroke, with its reported prevalence ranging from 12% to 49% (1, 2). The main symptoms of SHS include pain, hyperalgesia, joint swelling and limitations in range of motion (ROM) (3). Post-stroke SHS is also named type I complex ...
Source: Frontiers in Neurology - April 26, 2019 Category: Neurology Source Type: research

World-Wide Efficacy of Bone Marrow Derived Mesenchymal Stromal Cells in Preclinical Ischemic Stroke Models: Systematic Review and Meta-Analysis
Conclusions: Our results show worldwide efficacy of BM-MSCs in improving functional outcomes in pre-clinical animal models of stroke and support testing these cells in clinical trials in various ranges of time windows using different delivery routes. The continued growing number of publications showing functional benefit of BM-MSCs are now adding limited value to an oversaturated literature spanning 18 years. Researchers should focus on identifying definitive mechanisms on how BM-MSCs lead to benefit in stroke models. Introduction Ischemic stroke is the 5th leading cause of death and the leading cause of long term di...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Frequency of Hemorrhage on Follow Up Imaging in Stroke Patients Treated With rt-PA Depending on Clinical Course
Conclusions: Frequency of hemorrhagic transformation in Routine follow-up brain imaging and consecutive changes in therapeutic management were different depending on clinical course measured by NHISS score. Introduction Brain imaging 24–36 h after systemic thrombolysis for acute ischemic stroke is recommended in American Stroke Association and European Stroke Organization guidelines (1, 2). Brain imaging is performed to detect secondary bleeding or hemorrhagic transformation in order to adapt medical stroke prevention if necessary. Guideline recommendations are based on the results of the first study on rt-PA...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Development of a participatory, tailored behaviour change intervention to increase active practice during inpatient stroke rehabilitation.
CONCLUSIONS: This example of collaborative implementation research can be used and adapted by clinicians and researchers in other rehabilitation services. IMPLICATIONS FOR REHABILITATION Rehabilitation staff can be actively involved in designing behaviour change interventions. Behaviour change interventions should target local barriers to increase activity levels and practice completed by stroke inpatients. The process of co-designing behaviour change interventions has the potential to improve the uptake of a strategy such as ward-based practice books, by more precisely identifying local barriers and possible solutions. ...
Source: Disability and Rehabilitation - April 14, 2019 Category: Rehabilitation Authors: Stewart C, Power E, McCluskey A, Kuys S Tags: Disabil Rehabil Source Type: research

The Paradoxical Protective Effect of Liver Steatosis on Severity and Functional Outcome of Ischemic Stroke
Conclusions: Our study shows that a higher burden of liver steatosis seems to be associated with less severe stroke and better functional outcome after ischemic stroke or TIA. Introduction Non-alcoholic fatty liver disease (NAFLD) is a spectrum of diseases from simple steatosis to steatohepatitis with varying degree of fibrosis, and liver cirrhosis (1, 2). NAFLD is becoming the most common chronic liver disease worldwide including Korea, affecting approximately 25% of the general population (3, 4). NAFLD is closely associated with obesity, insulin resistance, and type 2 diabetes mellitus, and is even recognized as ...
Source: Frontiers in Neurology - April 12, 2019 Category: Neurology Source Type: research

Outcomes for Patients With In-Hospital Stroke: A Multicenter Study From the Australian Stroke Clinical Registry (AuSCR)
The quality of care and outcomes for people who experience stroke whilst in hospital for another condition has not been previously studied in Australia.
Source: Journal of Stroke and Cerebrovascular Diseases - February 26, 2019 Category: Neurology Authors: Dominique A. Cadilhac, Monique F. Kilkenny, Natasha A. Lannin, Helen M. Dewey, Christopher R. Levi, Kelvin Hill, Brenda Grabsch, Rohan Grimley, David Blacker, Amanda G. Thrift, Sandy Middleton, Craig S. Anderson, Geoffrey A. Donnan, On behalf of the Austr Source Type: research

Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012)
Introduction: Having a low level of physical activity is an established risk factor for stroke, but little is known about the importance of common sedentary behavior —television viewing—to stroke risk. Methods: We conducted a retrospective analysis of data that were collected as part of the longitudinal Australian Diabetes, Obesity, and Lifestyle study. Stroke events reported during the study (between baseline assessment in 1999-2000 and April 2011) were con firmed using adjudication based on medical records.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2019 Category: Neurology Authors: Toby B. Cumming, Elizabeth Holliday, David Dunstan, Coralie English Source Type: research

Quality of Life Is Poorer for Patients With Stroke Who Require an Interpreter Brief Report
Background and Purpose—In multicultural Australia, some patients with stroke cannot fully understand, or speak, English. Language barriers may reduce quality of care and consequent outcomes after stroke, yet little has been reported empirically.Methods—An observational study of patients with stroke or transient ischemic attack (2010–2015) captured from 45 hospitals participating in the Australian Stroke Clinical Registry. The use of interpreters in hospitals, which is routinely documented, was used as a proxy for severe language barriers. Health-Related Quality of Life was assessed using the EuroQoL-5 dimension-3 lev...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Monique F. Kilkenny, Natasha A. Lannin, Craig S. Anderson, Helen M. Dewey, Joosup Kim, Karen Barclay-Moss, Chris Levi, Steven Faux, Kelvin Hill, Brenda Grabsch, Sandy Middleton, Amanda G. Thrift, Rohan Grimley, Geoffrey Donnan, Dominique A. Cadilhac Tags: Race and Ethnicity, Mortality/Survival, Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Focal Cerebral Arteriopathy Clinical Sciences
Conclusions—Corticosteroid treatment may provide additional benefit over AT for improved neurological outcome in childhood AIS because of focal cerebral arteriopathy. Larger prospective studies are warranted to further investigate these differences and understand mechanisms by which steroids modify outcome.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Maȷa Steinlin, Sandra Bigi, Belinda Stoȷanovski, Jay Gaȷera, Maria Regenyi, Marwan El–Koussy, Mark T. Mackay Tags: Ischemic Stroke Original Contributions Source Type: research

Community-Based Intervention to Improve Cardiometabolic Targets in Patients With Stroke Clinical Sciences
Conclusions—The intervention in this largely negative trial only had a detectable effect on attaining target for lipids but not for other factors at 12 months or any factor at 24 months. This limited effect may be attributable to inadequate uptake of behavioral/lifestyle interventions, highlighting the need for new or better approaches to achieve meaningful behavioral change.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: ACTRN12608000166370.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Muideen T. Olaiya, Dominique A. Cadilhac, Joosup Kim, Mark R. Nelson, Velandai K. Srikanth, Richard P. Gerraty, Christopher F. Bladin, Sharyn M. Fitzgerald, Thanh Phan, Judith Frayne, Amanda G. Thrift Tags: Lifestyle, Risk Factors, Secondary Prevention, Treatment, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Inequities in access to inpatient rehabilitation after stroke: an international scoping review.
Conclusion Recommendations regarding which patients with moderate and severe strokes should access ongoing rehabilitation are inconsistent. Clinical practice guidelines from different countries regarding post-stroke rehabilitation do not always reflect the evidence regarding the likely benefits to people with stroke. Inequity in access to rehabilitation after stroke is an international issue. PMID: 28835194 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 23, 2017 Category: Neurology Authors: Lynch EA, Cadilhac DA, Luker JA, Hillier SL Tags: Top Stroke Rehabil Source Type: research