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Total 316 results found since Jan 2013.

Excess Stroke Deaths in Kidney Transplant Recipients: A Retrospective Population-based Cohort Study Using Data Linkage
Conclusions. Kidney transplant recipients had excess stroke deaths, particularly at younger ages and women. Preexisting cerebrovascular disease was a potentially modifiable risk factor for stroke death, suggesting further studies of secondary stroke prevention for kidney transplant recipients.
Source: Transplantation - September 24, 2020 Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research

Stroke rehabilitation research translation in Australia: a survey of clinical trialists.
This study aims to investigate perceptions of Australian stroke clinical trialists' about implementation of their findings into practice, and what translation activities they embedded into trial protocols. MATERIALS AND METHOD: A descriptive cohort design and electronic survey was conducted. Three databases were searched to identify Australian stroke rehabilitation trials published between 2007 and 2017. Corresponding authors of the included trials were invited to complete an anonymous online survey about implementation of their trial intervention. RESULTS: Fifty-one trialists were invited to participate and 38 c...
Source: Disability and Rehabilitation - August 26, 2020 Category: Rehabilitation Authors: Jolliffe L, Hoffmann T, Laver K, McCluskey A, Lannin NA Tags: Disabil Rehabil Source Type: research

Where have our patients gone? The impact of COVID ‐19 on stroke imaging and intervention at an Australian stroke centre
ConclusionsThe significant decrease in volume of ‘code stroke’ activations and acute stroke imaging following lockdown was accompanied by a concomitant decrease in patients with LVOs and ECRs. The decrease in imaging was therefore not driven purely by patients with mild strokes and stroke mimics, but also included those with severe strokes. Si nce Australia had a low prevalence of COVID‐19, this observed decrease cannot be attributed to hospital congestion and is instead likely driven by patient fear.
Source: Journal of Medical Imaging and Radiation Oncology - August 19, 2020 Category: Radiology Authors: Shalini A Amukotuwa, Roland Bammer, Julian Maingard Tags: Medical Imaging —Original Article Source Type: research

Australian health professionals' perceptions about the management of return to driving early after stroke: a mixed methods study - Frith J, James C, Hubbard I, Warren-Forward H.
BACKGROUND: Stroke can affect a person's ability to drive a motor vehicle. In Australia, there is a 4-week restriction in driving after stroke and a 2-week restriction after transient ischemic attack. Concerns exist as to whether people discharged home fro...
Source: SafetyLit - August 17, 2020 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Australian health professionals' perceptions about the management of return to driving early after stroke: A mixed methods study.
CONCLUSIONS: Education of health professionals in RTD guidelines is recommended to improve the processes of care after stroke. PMID: 32787668 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 12, 2020 Category: Neurology Authors: Frith J, James C, Hubbard I, Warren-Forward H Tags: Top Stroke Rehabil Source Type: research

Longitudinal Stroke Recovery Associated With Dysregulation of Complement System —A Proteomics Pathway Analysis
Currently the longitudinal proteomic profile of post-ischemic stroke recovery is relatively unknown with few well-accepted biomarkers or understanding of the biological systems that underpin recovery. We aimed to characterize plasma derived biological pathways associated with recovery during the first year post event using a discovery proteomics workflow coupled with a topological pathway systems biology approach. Blood samples (n = 180, ethylenediaminetetraacetic acid plasma) were collected from a subgroup of 60 first episode stroke survivors from the Australian START study at 3 timepoints: 3–7 days (T1), 3-months (T2) ...
Source: Frontiers in Neurology - July 27, 2020 Category: Neurology Source Type: research

Aeromedical Retrieval for Stroke in Australia
Conclusion: Stroke patients living in rural areas were younger than those living in major cities (75 years, Stroke Audit Data), with aeromedically retrieved Indigenous patients being a decade younger than non-Indigenous patients. The current transfer times are largely outside the time windows for reperfusion methods. Future research should aim to facilitate more timely diagnosis and treatment of stroke.Cerebrovasc Dis
Source: Cerebrovascular Diseases - June 24, 2020 Category: Neurology Source Type: research

Acute kidney injury, stroke and death after cardiopulmonary bypass surgery: the role of perfusion flow and pressure.
CONCLUSIONS: Neither low perfusion pressure nor low perfusion flow during cardiopulmonary bypass were predictive of postoperative acute kidney injury, stroke or death. PMID: 32515271 [PubMed - as supplied by publisher]
Source: Perfusion - June 8, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Turner L, Hardikar A, Jose MD, Bhattarai K, Fenton C, Sharma R, Kirkland G, Jeffs L, Breslin M, Silva Ragaini B, Newland RF Tags: Perfusion Source Type: research

Population-based stroke surveillance using big data: state-wide epidemiological trends in admissions and mortality in New South Wales, Australia.
DISCUSSION: Improved prevention may have underpinned declining intracerebral haemorrhage rates while survival gains suggest that innovations in care are being successfully translated. Mortality in patients surviving the acute period is unchanged and may be increasing for subarachnoid haemorrhage warranting investment in post-discharge care and secondary prevention. PMID: 32449879 [PubMed - as supplied by publisher]
Source: Neurological Research - May 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research

The Characteristics of Patients With Possible Transient Ischemic Attack and Minor Stroke in the Hunter and Manning Valley Regions, Australia (the INSIST Study)
Conclusion: This study provides the first contemporary data on TIAMS or TIAMS-mimics in Australia. Community and health provider education is required to address the under-use of anticoagulation therapy in patients with known AF, possibly inappropriate use of antiplatelet therapy and possibly inappropriate discontinuation of antiplatelet or anticoagulation therapy.
Source: Frontiers in Neurology - May 14, 2020 Category: Neurology Source Type: research

Dose and setting of rehabilitation received after stroke in Queensland, Australia: a prospective cohort study.
CONCLUSION: Amount of therapy varied widely between rehabilitation pathways. Amount of therapy and chance of improvement in function were highest with inpatient rehabilitation. PMID: 32389061 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - May 10, 2020 Category: Rehabilitation Authors: Grimley RS, Rosbergen IC, Gustafsson L, Horton E, Green T, Cadigan G, Kuys S, Andrew NE, Cadilhac DA Tags: Clin Rehabil Source Type: research

Opposing Associations of Stress and Resilience With Functional Outcomes in Stroke Survivors in the Chronic Phase of Stroke: A Cross-Sectional Study
Stroke survivors report significant levels of psychological distress post stroke. To date, most studies conducted have focused on the relationship between psychological stress and functional outcomes in the acute phase of stroke. However, no studies had considered the role of stress over the chronic phase, where stress may continue to exert negative effects on cognitive and psychological processes. Further, the role of potentially modulatory variables, such as psychological resilience, on stroke outcomes has been understudied. The purpose of this study was to consider the relationships between stress and resilience with fu...
Source: Frontiers in Neurology - April 21, 2020 Category: Neurology Source Type: research

Incidence of Hospitalization for Stroke in Queensland, Australia: Younger Adults at Risk
Background: Trends in the incidence of stroke are important for health care planning. Information is particularly scarce in Australia, due to the paucity of studies with access to recent, large-scale, longitudinal datasets. In this paper we investigated the incidence of hospitalization for stroke by sex, age, and subtype in the whole State of Queensland (Australia). Methods: We obtained data of all hospital admissions for stroke in Queensland from 2002 to 2015. Age standardized hospitalization rates for first-ever stroke were calculated along with WHO adjusted rates.
Source: Journal of Stroke and Cerebrovascular Diseases - April 8, 2020 Category: Neurology Authors: Deanna Anderlini, Guy Wallis, Welber Marinovic Source Type: research

Improving acute stroke care in regional hospitals: clinical evaluation of the Victorian Stroke Telemedicine program.
CONCLUSIONS: Telemedicine has provided Victorian regional hospitals access to expert care for emergency department patients with suspected acute stroke. Eligible patients with ischaemic stroke are now receiving stroke thrombolysis more quickly and safely. PMID: 32255520 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - April 8, 2020 Category: General Medicine Tags: Med J Aust Source Type: research

Augmented Performance Feedback during Robotic Gait Therapy Results in Moderate Intensity Cardiovascular Exercise in Subacute Stroke
Low cardiovascular fitness is common poststroke. Conventional subacute stroke rehabilitation does not meet Australian National Stroke Guidelines for cardiovascular exercise, particularly in mobility-dependent patients. Walking robotics can potentially achieve recommended cardiovascular exercise with these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 30, 2020 Category: Neurology Authors: Nicole Prideaux, Maayken van den Berg, Claire Drummond, Christopher Barr Source Type: research

Evaluation of a staff behaviour change intervention to increase the use of ward-based practice books and active practice during inpatient stroke rehabilitation: a phase-1 pre-post observational study.
CONCLUSION: A staff behaviour change intervention has the potential to increase the number of stroke survivors receiving ward-based practice books but did not increase active practice. PMID: 32204599 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - March 22, 2020 Category: Rehabilitation Authors: Stewart C, Power E, McCluskey A, Kuys S, Lovarini M Tags: Clin Rehabil Source Type: research

Safety and efficacy of GABAA α5 antagonist S44819 in patients with ischaemic stroke: a multicentre, double-blind, randomised, placebo-controlled trial
Publication date: March 2020Source: The Lancet Neurology, Volume 19, Issue 3Author(s): Hugues Chabriat, Claudio L Bassetti, Ute Marx, Marie-Laure Audoli-Inthavong, Aurore Sors, Estelle Lambert, Marine Wattez, Dirk M Hermann, Katharina ALTHAUS, Sergi AMARO, Hee-Joon BAE, Zbigniew BAK, Leonardo BARBARINI, Pietro BASSI, Rodrigo BAZAN, Daniel BERECZKI, Tomasz BERKOWICZ, Joerg BERROUSCHOT, Dylan BLACQUIERE, Waldemar BROLASummaryBackgroundS44819, a selective GABAA α5 receptor antagonist, reduces tonic post-ischaemic inhibition of the peri-infarct cortex. S44819 improved stroke recovery in rodents and increased cortical excitabi...
Source: The Lancet Neurology - February 19, 2020 Category: Neurology Source Type: research

Spirituality and resilience among family  caregivers of survivors of stroke: A scoping review.
CONCLUSIONS: Spirituality and resilience following stroke are essential factors in caregiver adjustment following stroke. Further research with a focus on causality and the link between spirituality, resilience and adjustment in this population is needed. PMID: 32039873 [PubMed - as supplied by publisher]
Source: NeuroRehabilitation - February 11, 2020 Category: Rehabilitation Tags: NeuroRehabilitation Source Type: research

Differences in stroke risk and cardiovascular mortality for Aboriginal and other Australian patients with atrial fibrillation.
CONCLUSION: Stroke risk and cardiovascular mortality are markedly higher for Aboriginal than non-Aboriginal patients with atrial fibrillation, particularly for patients under 60. Strategies for providing evidence-based therapies and cardiovascular prevention to Aboriginal people with atrial fibrillation must be improved. PMID: 32030754 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - February 8, 2020 Category: General Medicine Tags: Med J Aust Source Type: research

The Tasmanian Atrial Fibrillation Study (TAFS): Differences in Stroke Prevention According to Sex.
Conclusion and Relevance: Female patients with a high stroke risk were less likely to receive guideline-recommended treatment. This study provides new information on prescribing trends within the Australian setting and highlights the opportunity to improve the management of female patients with AF and 1 or more additional stroke risk factors. PMID: 32019321 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - February 3, 2020 Category: Drugs & Pharmacology Authors: Pilcher SM, Alamneh EA, Chalmers L, Bereznicki LR Tags: Ann Pharmacother Source Type: research

Featured Review: Treating depression after stroke
Depression is common after stroke yet often is not detected or inadequately treated.Review authors from Australia, Canada, Taiwan and the UK asked, " Do pharmacological treatments, non ‐invasive brain stimulation, psychological treatments, or combination treatments reduce the proportion of people with depression or the extent of depressive symptoms after stroke? "The authors included trials that reported on the use of pharmacological, non ‐invasive brain stimulation, psychological, and combination therapy interventions to treat depression after stroke. Mean age of people included in the trials ranged from 54 to 78 year...
Source: Cochrane News and Events - January 28, 2020 Category: Information Technology Authors: Katie Abbotts Source Type: news

Challenges of delivering evidence-based stroke services for rural areas in Australia.
CONCLUSION: Evidence-based stroke care, aligned with current national standards is the key to providing adequate stroke services in rural Australia. Improved health service resourcing and better utilisation of currently available resources are options for achieving elements of evidence-based stroke care. IMPLICATIONS FOR PUBLIC HEALTH: Availability of adequate services for stroke patients directly impacts public health as it determines health outcomes for these patients. Indirect implications for public health include the effects on health professionals and the general public. PMID: 31990135 [PubMed - as supplied by publisher]
Source: The Australian Journal of Rural Health - January 27, 2020 Category: Rural Health Authors: Prior SJ, Reeves NS, Campbell SJ Tags: Aust J Rural Health Source Type: research

Occupational engagement following mild stroke in the Australian context using the occupational gaps questionnaire.
Conclusions and significance: The English version of the OGQ was found to be a feasible instrument for identifying occupational gaps following mild stroke and may be suitable to support research and clinical practice with this population. PMID: 31906780 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - January 8, 2020 Category: Occupational Health Tags: Scand J Occup Ther Source Type: research

Addressing inequity in acute stroke care requires attention to each component of regional workflow.
Authors: Watson T, Tiu J, Clissold B PMID: 31785010 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - December 2, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Advances in stroke medicine.
Authors: Cheng S, Richards T PMID: 31763695 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - November 26, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
A randomized, prospective study from the United Kingdom and Australia was conducted between February 24, 2006 and June 17, 2013.
Source: Journal of Vascular Surgery - November 22, 2019 Category: Surgery Authors: H.S. Markus, C. Levi, A. King, J. Madigan, J. Norris, Cervical Artery Dissection in Stroke Study (CADISS) Investigators. Tags: There is no difference in treatment of carotid or vertebral artery dissection with antiplatelet vs anticoagulant therapy Source Type: research

Arterial Stiffness and Indices of Left Ventricular Diastolic Dysfunction in Patients with Embolic Stroke of Undetermined Etiology.
Conclusions: Increased arterial stiffness and indices of diastolic dysfunction as well as a higher NT-proBNP level are significantly associated with ESUS. These parameters require further scrutiny over time to understand their impact on the development of symptomatic heart failure. The ClinicalTrials.gov identifier is NCT03377465. PMID: 31612072 [PubMed - in process]
Source: Disease Markers - October 17, 2019 Category: Laboratory Medicine Tags: Dis Markers Source Type: research

Device closure for patent foramen ovale in patients with cryptogenic stroke: a paradigm in evidence.
Authors: Ha FJ, Adams H, Palmer S PMID: 31523821 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - September 17, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia).
Abstract Utstein-style reporting templates provide a structured framework with which to compare systems of care for cardiac arrest. The 2004 Utstein reporting template encompassed both out-of-hospital and in-hospital cardiac arrest. A 2015 update of the Utstein template focused on out-of-hospital cardiac arrest, which makes this update of the in-hospital template timely. Representatives of the International Liaison Committee on Resuscitation developed an updated in-hospital Utstein reporting template iteratively by meeting face-to-face, by teleconference, and by online surveys between 2013 and 2018. Data elements ...
Source: Circulation - September 15, 2019 Category: Cardiology Authors: Nolan JP, Berg RA, Andersen LW, Bhanji F, Chan PS, Donnino MW, Lim SH, Ma MH, Nadkarni VM, Starks MA, Perkins GD, Morley PT, Soar J, Utstein Collaborators Tags: Circulation Source Type: research

Are we there yet? Exploring the journey to quality stroke care for Aboriginal and Torres Strait Islander peoples in rural and remote Queensland.
CONCLUSION: An integrated patient centred model of care that spans the care continuum and places value on an extended role for the Aboriginal and Torres Strait Islander health worker workforce is indicated, as is an increased utilisation of allied health and specialist follow-up close to home. PMID: 31487467 [PubMed - in process]
Source: Rural and Remote Health - September 7, 2019 Category: Rural Health Tags: Rural Remote Health Source Type: research

Inclusion of a care bundle for fever, hyperglycaemia and swallow management in a National Audit for acute stroke: evidence of upscale and spread
In the Quality in Acute Stroke Care (QASC) trial undertaken in stroke units (SUs) located in New South Wales (NSW), Australia (2005 –2010), facilitated implementation of a nurse-led care bundle to manage fever,...
Source: Implementation Science - September 2, 2019 Category: Health Management Authors: Tara Purvis, Sandy Middleton, Louise E. Craig, Monique F. Kilkenny, Simeon Dale, Kelvin Hill, Catherine D ’Este and Dominique A. Cadilhac Tags: Research Source Type: research

Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depressive Symptom Scores.
Conclusions: We provide evidence that fALFF is sensitive to changes in poststroke depressive symptom severity and implicates frontostriatal and cerebellar regions, consistent with previous studies. The use of multiband analysis could be an effective method to examine neural correlates of depression after stroke. The START-PrePARE trial is registered with the Australian New Zealand Clinical Trial Registry, number ACTRN12610000987066. PMID: 31467520 [PubMed - in process]
Source: Neural Plasticity - August 31, 2019 Category: Neurology Authors: Goodin P, Lamp G, Vidyasagar R, Connelly A, Rose S, Campbell BCV, Tse T, Ma H, Howells D, Hankey GJ, Davis S, Donnan G, Carey LM Tags: Neural Plast Source Type: research

Air retrieval for clot retrieval; time-metrics and outcomes of stroke patients from rural and remote regions air-transported for mechanical thrombectomy at a state stroke unit
ConclusionWith the availability of an efficient aeromedical retrieval service, LVO stroke patients in rural and remote regions can achieve excellent outcomes following transfer to a high volume thrombectomy unit, even if distances involved are very large.
Source: Journal of Clinical Neuroscience - August 20, 2019 Category: Neuroscience Source Type: research

Googling Location for Operating Base of Mobile Stroke Unit in Metropolitan Sydney
Conclusions: Any of the ECR capable hospital can serve as a hub for MSU. We provide a method to identify the hub based on location of suburbs less well served by other hospital.
Source: Frontiers in Neurology - August 5, 2019 Category: Neurology Source Type: research

The lived experience of supporting people with mild stroke.
Conclusions and Significance: Whilst spouses generally return to their daily routines after a family members' mild stroke, some will experience increased time pressures and occupational disruptions. Health providers should prepare spouses for behavioral and emotional changes in people with mild stroke. PMID: 31264497 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - July 4, 2019 Category: Occupational Health Tags: Scand J Occup Ther Source Type: research

Application of Strategic Transport Model and Google Maps to Develop Better Clot Retrieval Stroke Service
Discussion: The results from strategic transport model are similar to those from Google Maps. In this paper we illustrate how this method can be applied in designing and forecast stroke service model in different cities in Australia and around the world.
Source: Frontiers in Neurology - June 27, 2019 Category: Neurology Source Type: research

Comparison of Echocardiographic Parameters of Left Atrial and Ventricular Function between Young Stroke vs Lone Atrial Fibrillation vs Healthy Controls
Background: Stroke is one of Australia's leading causes of morbidity and mortality with a significant percentage classified as cryptogenic. The nature and aetiology of cryptogenic stroke remains elusive, with a proportion believed to be cardio-embolic secondary to subclinical paroxysmal atrial fibrillation (AF). We aim to gain mechanistic insights into the pathophysiology of cryptogenic stroke in the young by comparing cardiac structural and functional differences in patients with young stroke, lone AF and healthy controls.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: A. Bhat, S. Khanna, H. Chen, G. Gan, R. MacIntyre, T. Tan Tags: 254 Source Type: research

Is Incorrect Anti-Coagulation Dosing Contributing to Ischaemic Stroke Burden? A Retrospective Single-Centre Study from Regional New South Wales, Australia
Background: Atrial fibrillation (AF) contributes to 30% of ischaemic stroke presentations. Low doses of anti-coagulants are often prescribed to prevent stroke but ameliorate bleeding risk.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: P. Bamford, M. Ray, S. Cheruvu, M. Parkinson, C. Said, J. Trappel, J. Rogers Tags: 195 Source Type: research

Help-seeking and people with aphasia who have mood problems after stroke: perspectives of speech-language pathologists.
CONCLUSIONS & IMPLICATIONS: SLPs report both universal barriers to help-seeking and those specific to their clients with aphasia and attempts to overcome these; however, there appears to be a dearth of accessible mental health services for people with aphasia known to SLPs, including psychological/counselling professionals who are skilled in communicating with people with aphasia. Health professionals working within and across post-stroke and mental health services should recognize that people with post-stroke aphasia are susceptible to a decline in mental health, are amenable to formal (and tailored) psychological sup...
Source: International Journal of Language and Communication Disorders - June 16, 2019 Category: Speech-Language Pathology Authors: Ryan B, Bohan J, Kneebone I Tags: Int J Lang Commun Disord Source Type: research

Stroke Risk Factors and Outcomes in Indigenous Verse Non-Indigenous Australians
Background: Stroke risk factors are well known, but there is little data on the prevalence of stroke risk factors in Indigenous Australian cohorts. We aim to assess the risk factors and the outcomes after stroke and compare these in Indigenous and non-Indigenous Australians presenting with acute strokes to the Wagga Wagga Rural Referral Hospital.
Source: Heart, Lung and Circulation - May 24, 2019 Category: Cardiology Authors: Angela Dos Santos, Katherine Mohr, Martin Jude, Neil Simon, Candice Delcourt Tags: P20 Source Type: research

Stroke Incidence and Outcomes in Indigenous Australians
We present the first prospective population-based pilot study of stroke incidence and outcomes in Indigenous Australians.
Source: Heart, Lung and Circulation - May 24, 2019 Category: Cardiology Authors: Angela Dos Santos, Anna Balabanski, Tim Kleinig, Amanda Thrift, Alex Brown, Judith Katzenellenbogen, Edmung Cheong Tags: P19 Source Type: research

Evaluating Personal Stroke Narratives from Bilingual Greek-English Immigrants with Aphasia
Conclusion: The results have implications for policy-makers providing health and welfare services to ageing immigrant populations. The findings are also relevant to other countries that have large immigrant populations of stroke survivors.Folia Phoniatr Logop 2019;71:101 –115
Source: Folia Phoniatrica et Logopaedica - May 14, 2019 Category: Speech-Language Pathology Source Type: research

Advances in stroke medicine.
Authors: Campbell BC Abstract In recent years, reperfusion therapies such as intravenous thrombolysis and endovascular thrombectomy for ischaemic stroke have dramatically reduced disability and revolutionised stroke management. Thrombolysis with alteplase is effective when administered to patients with potentially disabling stroke, who are not at high risk of bleeding, within 4.5 hours of the time the patient was last known to be well. Emerging evidence suggests that other thrombolytics such as tenecteplase may be even more effective. Treatment may be possible beyond 4.5 hours in patients selected using brain imagi...
Source: Medical Journal of Australia - May 6, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Outcomes for Patients With In-Hospital Stroke: A Multicenter Study From the Australian Stroke Clinical Registry (AuSCR)
The quality of care and outcomes for people who experience stroke whilst in hospital for another condition has not been previously studied in Australia.
Source: Journal of Stroke and Cerebrovascular Diseases - February 26, 2019 Category: Neurology Authors: Dominique A. Cadilhac, Monique F. Kilkenny, Natasha A. Lannin, Helen M. Dewey, Christopher R. Levi, Kelvin Hill, Brenda Grabsch, Rohan Grimley, David Blacker, Amanda G. Thrift, Sandy Middleton, Craig S. Anderson, Geoffrey A. Donnan, On behalf of the Austr Source Type: research

Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012)
Introduction: Having a low level of physical activity is an established risk factor for stroke, but little is known about the importance of common sedentary behavior —television viewing—to stroke risk. Methods: We conducted a retrospective analysis of data that were collected as part of the longitudinal Australian Diabetes, Obesity, and Lifestyle study. Stroke events reported during the study (between baseline assessment in 1999-2000 and April 2011) were con firmed using adjudication based on medical records.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2019 Category: Neurology Authors: Toby B. Cumming, Elizabeth Holliday, David Dunstan, Coralie English Source Type: research

Quality of Life Is Poorer for Patients With Stroke Who Require an Interpreter Brief Report
Background and Purpose—In multicultural Australia, some patients with stroke cannot fully understand, or speak, English. Language barriers may reduce quality of care and consequent outcomes after stroke, yet little has been reported empirically.Methods—An observational study of patients with stroke or transient ischemic attack (2010–2015) captured from 45 hospitals participating in the Australian Stroke Clinical Registry. The use of interpreters in hospitals, which is routinely documented, was used as a proxy for severe language barriers. Health-Related Quality of Life was assessed using the EuroQoL-5 dimension-3 lev...
Source: Stroke - February 26, 2018 Category: Neurology Authors: Monique F. Kilkenny, Natasha A. Lannin, Craig S. Anderson, Helen M. Dewey, Joosup Kim, Karen Barclay-Moss, Chris Levi, Steven Faux, Kelvin Hill, Brenda Grabsch, Sandy Middleton, Amanda G. Thrift, Rohan Grimley, Geoffrey Donnan, Dominique A. Cadilhac Tags: Race and Ethnicity, Mortality/Survival, Quality and Outcomes, Ischemic Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Focal Cerebral Arteriopathy Clinical Sciences
Conclusions—Corticosteroid treatment may provide additional benefit over AT for improved neurological outcome in childhood AIS because of focal cerebral arteriopathy. Larger prospective studies are warranted to further investigate these differences and understand mechanisms by which steroids modify outcome.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Maȷa Steinlin, Sandra Bigi, Belinda Stoȷanovski, Jay Gaȷera, Maria Regenyi, Marwan El–Koussy, Mark T. Mackay Tags: Ischemic Stroke Original Contributions Source Type: research

Community-Based Intervention to Improve Cardiometabolic Targets in Patients With Stroke Clinical Sciences
Conclusions—The intervention in this largely negative trial only had a detectable effect on attaining target for lipids but not for other factors at 12 months or any factor at 24 months. This limited effect may be attributable to inadequate uptake of behavioral/lifestyle interventions, highlighting the need for new or better approaches to achieve meaningful behavioral change.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: ACTRN12608000166370.
Source: Stroke - August 28, 2017 Category: Neurology Authors: Muideen T. Olaiya, Dominique A. Cadilhac, Joosup Kim, Mark R. Nelson, Velandai K. Srikanth, Richard P. Gerraty, Christopher F. Bladin, Sharyn M. Fitzgerald, Thanh Phan, Judith Frayne, Amanda G. Thrift Tags: Lifestyle, Risk Factors, Secondary Prevention, Treatment, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Inequities in access to inpatient rehabilitation after stroke: an international scoping review.
Conclusion Recommendations regarding which patients with moderate and severe strokes should access ongoing rehabilitation are inconsistent. Clinical practice guidelines from different countries regarding post-stroke rehabilitation do not always reflect the evidence regarding the likely benefits to people with stroke. Inequity in access to rehabilitation after stroke is an international issue. PMID: 28835194 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 23, 2017 Category: Neurology Authors: Lynch EA, Cadilhac DA, Luker JA, Hillier SL Tags: Top Stroke Rehabil Source Type: research