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The impact of night-shift work on platelet function in healthy medical staff.
CONCLUSIONS: Although platelet aggregation did not increase, there was an increase in serum COX-metabolized eicosanoid mediators such as TxB2 in healthy medical staff after night-shift work. This platelet hypersensitivity may be one of the mechanisms underlying the significant association between night-shift work and adverse cardiovascular outcomes. PMID: 29669967 [PubMed - as supplied by publisher]
Source: Journal of Occupational Health - April 21, 2018 Category: Occupational Health Tags: J Occup Health Source Type: research

A look inside the arteries: moving from event rates to subclinical measures of disease
Cardiovascular disease (CVD) is still the most important cause of death worldwide, with ischaemic heart disease and stroke being the most frequent subcategories.1 Next to premature mortality, morbidity and reduced quality of life are consequences which can be devastating to the individual as well as to society. However, the final dreaded event, such as myocardial infarction, stroke or sudden cardiac death, caused by plaque rupture and thrombosis, presents only the very last stage of a disease process that has long been ongoing.2 The underlying pathology for most cardiovascular (CV) and many cerebrovascular events is athero...
Source: Occupational and Environmental Medicine - September 16, 2015 Category: Occupational Health Authors: Hoffmann, B. Tags: Commentary Source Type: research