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Specialty: Geriatrics
Condition: Thrombosis

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Total 41 results found since Jan 2013.

Transgender health and the impact of aging and menopause
Climacteric. 2023 Apr 3:1-7. doi: 10.1080/13697137.2023.2176217. Online ahead of print.ABSTRACTGender affirming hormone therapy (GAHT) is used by many transgender people to reduce gender incongruence and improve psychological functioning. As GAHT shares many similarities with menopausal hormone therapy, clinicians supporting people through menopause are ideally placed to manage GAHT. This narrative review provides an overview of transgender health and discusses long-term effects of GAHT to consider when managing transgender individuals across the lifespan. Menopause is less relevant for transgender individuals who take GAH...
Source: Climacteric - April 3, 2023 Category: Geriatrics Authors: A S Cheung B J Nolan S Zwickl Source Type: research

SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients
AbstractSARS-CoV-2 is a recently identified coronavirus that causes the current pandemic disease known as COVID-19. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) as a receptor, suggesting that the initial steps of SARS-CoV-2 infection may have an impact on the renin-angiotensin system (RAS). Several processes are influenced by RAS in the brain. The neurological symptoms observed in COVID-19 patients, including reduced olfaction, meningitis, ischemic stroke, cerebral thrombosis, and delirium, could be associated with RAS imbalance. In this review, we focus on the potential role of disturbances in the RAS as a cause...
Source: AGE - February 14, 2022 Category: Geriatrics Source Type: research

The impact of micronized progesterone on cardiovascular events - a systematic review
In conclusion, while available data suggest that MP as a component in combined MHT may have a neutral effect on the vascular system, more RCTs investigating the impact of MP alone or in combined MHT on vascular primary endpoints are needed.PMID:35112635 | DOI:10.1080/13697137.2021.2022644
Source: Climacteric - February 3, 2022 Category: Geriatrics Authors: L M Kaemmle A Stadler H Janka M von Wolff P Stute Source Type: research

Risk factors of pulmonary embolism in the elderly patients: a retrospective study
CONCLUSION: Blood levels of D-dimer and CRP may be potent screening markers for PE especially among elderly patients.PMID:35001332 | DOI:10.1007/s40520-021-02031-6
Source: Aging Clinical and Experimental Research - January 10, 2022 Category: Geriatrics Authors: Yuxia Ma Yi Liu Ying Zhi Haibin Wang Mei Yang Jieting Niu Li Zhao Pengsheng Wang Source Type: research

Increased procoagulant platelet levels are predictive of death in COVID-19
AbstractPrior research has identified abnormal platelet procoagulant responses in COVID-19. Coated-platelets, a form of procoagulant platelets, support thrombin formation and are elevated in ischemic stroke patients with increased risk for recurrent infarction. Our goal was to examine changes in coated-platelet levels over the course of COVID-19 infection and determine their association with disease severity, thrombosis, and death. Coated-platelet levels were assayed after admission and repeated weekly in COVID-19 patients, and in COVID-19 negative controls. Receiver operator characteristic (ROC) analysis was used to calcu...
Source: AGE - June 9, 2021 Category: Geriatrics Source Type: research

Trends in Anticoagulant Use at Nursing Home Admission and Variation by Frailty and Chronic Kidney Disease Among Older Adults with Atrial Fibrillation
ConclusionsWhile the proportion of residents with AF receiving oral anticoagulants at admission increased following the approval of DOACs, over 40% remained untreated. Among those treated, use of a DOAC increased, while warfarin use declined. The impact of these recent treatment patterns on the balance between benefit and harm among residents warrant further investigation.
Source: Drugs and Aging - April 21, 2021 Category: Geriatrics Source Type: research

Individualized predictions of early isolated distal deep vein thrombosis in patients with acute ischemic stroke: a retrospective study
This study aimed...
Source: BMC Geriatrics - February 25, 2021 Category: Geriatrics Authors: Hao-Ran Cheng, Gui-Qian Huang, Zi-Qian Wu, Yue-Min Wu, Gang-Qiang Lin, Jia-Ying Song, Yun-Tao Liu, Xiao-Qian Luan, Zheng-Zhong Yuan, Wen-Zong Zhu, Jin-Cai He and Zhen Wang Tags: Research article Source Type: research

A medical history of arterial thrombosis is a strong predictor of post-operative myocardial infarction and stroke in patients with hip fractures —a nationwide cohort study
ConclusionMI and stroke after hip fractures are overlooked and serious complications. Persons with elevated risk can be identified at admission, based on their medical history.
Source: Age and Ageing - January 28, 2021 Category: Geriatrics Source Type: research

Prevalence of atrial fibrillation and outcomes in older long-term care residents: a systematic review
Conclusionestimates of AF prevalence and factors associated with AC prescription varied extensively. Limited data on outcomes prevent the drawing of definitive conclusions. We recommend panel data collection and systems for linkage to create longitudinal cohorts to provide more robust evidence.
Source: Age and Ageing - December 31, 2020 Category: Geriatrics Source Type: research