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Increased platelet activation in sleep apnea subjects with intermittent hypoxemia.
CONCLUSIONS: Increased platelet activation was present in otherwise healthy subjects with intermittent nocturnal hypoxemia due to underlying OSA. This prothrombotic milieu in the vasculature is likely a key contributing factor toward development of thrombosis and cardiovascular disease. TRIAL REGISTRATION: NCT00859950. PMID: 32036486 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - February 7, 2020 Category: Sleep Medicine Authors: Krieger AC, Anand R, Hernandez-Rosa E, Maidman A, Milrad S, DeGrazia MQ, Choi AJ, Oromendia C, Marcus AJ, Drosopoulos JHF Tags: Sleep Breath Source Type: research

Diurnal and Twenty-Four-Hour Patterning of Human Diseases: Cardiac, Vascular, and Respiratory Diseases, Conditions, and Syndromes
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24-hour patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhyth...
Source: Sleep Medicine Reviews - July 18, 2014 Category: Sleep Medicine Authors: Michael H. Smolensky, Francesco Portaluppi, Roberto Manfredini, Ramon C. Hermida, Ruana Tiseo, Linda L. Sackett-Lundeen, Erhard Haus Source Type: research

Diurnal and twenty-four hour patterning of human diseases: Cardiac, vascular, and respiratory diseases, conditions, and syndromes
Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, e.g., respiratory ones of viral and allergic rhinorrhea, reversible (asthma) and non-reversible (bronchitis and emphysema) chronic obstructive pulmonary disease, cystic fibrosis, high altitude pulmonary edema, and decompression sickness; cardiac ones of atrial premature beats and tachycardia, paroxysmal atrial fibrillation, 3rd degree atrial-ventricular block, paroxysmal supraventricular tachycardia, ventricular premature beats, ventricular tachyarrhythm...
Source: Sleep Medicine Reviews - July 18, 2014 Category: Sleep Medicine Authors: Michael H. Smolensky, Francesco Portaluppi, Roberto Manfredini, Ramon C. Hermida, Ruana Tiseo, Linda L. Sackett-Lundeen, Erhard L. Haus Tags: Clinical review Source Type: research