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Source: Journal of the Neurological Sciences
Condition: Thrombosis
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Total 32 results found since Jan 2013.
Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review
One of the rare but potentially serious side effects of COVID-19 vaccination is arterial and venous thrombosis. Acute ischemic stroke (AIS) cases have been reported post COVID-19 vaccination. Herein, we systematically reviewed the reported cases of AIS after COVID-19 vaccination.
Source: Journal of the Neurological Sciences - June 20, 2022 Category: Neurology Authors: Zahra Kolahchi, MohammadHossein Khanmirzaei, Ashkan Mowla Tags: Review Article Source Type: research
Cerebral edema in acute stroke: Effect of thrombolytic treatment
Cerebral edema (CED) is a common complication of ischemic stroke in Intensive Care Unit. Although frequently observed in patients undergoing intravenous thrombolytic (IVT) treatment, the pathogenic role of recombinant tissue plasminogen activator (rtPA) in CED induction has not yet been definitively clarified. The aim of our study is to verify the relationship between CED and rtPA in patients affected by acute ischemic stroke, without reperfusion signs, evaluating the CED growth rate in the first week after stroke onset.
Source: Journal of the Neurological Sciences - February 22, 2022 Category: Neurology Authors: Giovanni Frisullo, Simone Bellavia, Irene Scala, Pierandrea Rizzo, Aldobrando Broccolini, Valerio Brunetti, Maria Pepe, Fabio Pilato, Roberta Morosetti, Giacomo Della Marca, Paolo Calabresi Source Type: research
Clot evaluation and distal embolization risk during mechanical thrombectomy in anterior circulation stroke
Clot features along with patients' clinical features may influence thrombus compactness predisposing at distal embolization during thrombectomy. The aim of this study was to evaluate thrombus features assessed by radiological and histopathological analysis along with patient-related features to predict distal embolization during thrombectomy.
Source: Journal of the Neurological Sciences - December 13, 2021 Category: Neurology Authors: Fabio Pilato, Iacopo Valente, Rosalinda Calandrelli, Andrea Alexandre, Vincenzo Arena, Marco Dell'Aquila, Aldobrando Broccolini, Giacomo Della Marca, Roberta Morosetti, Giovanni Frisullo, Valerio Brunetti, Marisa Distefano, Alessandro Pedicelli, Cesare Co Source Type: research
Re: Semerano A, Mamadou Z, Desilles JP, Sabben C, Bacigaluppi M, Piotin M, et al. Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings. Journal of the neurological sciences. 2021;427:117550
We read with interest the manuscript entitled “Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings“by Semerano et al., which adds to the body of literature related to the treatment of carotid webs [1].
Source: Journal of the Neurological Sciences - August 20, 2021 Category: Neurology Authors: Diogo C. Haussen, Alhamza R. Al-Bayati, Nirav Bhatt, Raul G. Nogueira Tags: Letter to the Editor Source Type: research
Carotid webs in large vessel occlusion stroke: Clinical, radiological and thrombus histopathological findings
Carotid webs are an under-recognized embolic source in patients with cryptogenic stroke. Limited resources currently exist to assist clinicians in stroke prevention for patients with symptomatic carotid webs (SCW). We aimed at analysing the clinical, radiological and procedural features of stroke patients with SCW undergoing endovascular thrombectomy (EVT), and to describe the histopathological composition of their occlusive thrombi.
Source: Journal of the Neurological Sciences - June 21, 2021 Category: Neurology Authors: Aurora Semerano, Zakaria Mamadou, Jean Philippe Desilles, Candice Sabben, Marco Bacigaluppi, Michel Piotin, Mickael Mazighi, Lucas Di Meglio, Michael Obadia Tags: Clinical short communication Source Type: research
Clopidogrel underactivity is a common in patients with acute symptomatic severe carotid stenosis
Clopidogrel is commonly used for secondary stroke prevention in patients with large vessel stenosis. Reduced Clopidogrel high on treatment platelet reactivity (CR) can lead to Clopidogrel underactivity (CU) causing acute thrombosis. However, the prevalence of CU among patients with acute symptomatic carotid disease remains unknown. Therefore, we aimed to find the prevalence and identify the predictors for CU among patients with acutely symptomatic carotid stenosis.
Source: Journal of the Neurological Sciences - April 14, 2021 Category: Neurology Authors: A. Honig, T. Sacagiu, A. Filioglo, N. Simaan, J. Kalish, J.M. Gomori, A. Horev, R.R. Leker, J.E. Cohen Tags: Clinical short communication Source Type: research
Stroke risk associated with carotid and aortic atherosclerosis in patients with atrial fibrillation: A systematic review
This review aimed to summarize the evidence on the risk of thromboembolism associated with carotid and aortic atherosclerosis in patients with AF, and the potential impact of their inclusion in current stroke risk stratification scores.
Source: Journal of the Neurological Sciences - April 10, 2021 Category: Neurology Authors: Jean Jacques Noubiap, Joseph Kamtchum-Tatuene, John L. Fitzgerald, Prashanthan Sanders Tags: Review Article Source Type: research
Cerebral thrombi of cardioembolic etiology have an increased content of neutrophil extracellular traps
Inflammation is emerging as an essential trigger for thrombosis. In the interplay between innate immunity and coagulation cascade, neutrophils and neutrophil extracellular traps (NETs) can promote thrombus formation and stabilization. In ischemic stroke, it is uncertain whether the involvement of the inflammatory component may differ in thrombi of diverse etiology. We here aimed to evaluate the presence of neutrophils and NETs in thrombi of diverse etiology retrieved by endovascular thrombectomy (EVT).
Source: Journal of the Neurological Sciences - February 21, 2021 Category: Neurology Authors: Angela Genchi, Aurora Semerano, Giorgia Serena Gullotta, Davide Strambo, Ghil Schwarz, Andrea Bergamaschi, Pietro Panni, Franco Simionato, Francesco Scomazzoni, Caterina Michelozzi, Mattia Pozzato, Norma Maugeri, Giancarlo Comi, Andrea Falini, Luisa Rover Source Type: research
Cerebral venous sinus thrombosis associated with SARS-CoV-2; a multinational case series
We present a series of CVST cases with SARS-CoV-2 infection.Methods In a multinational retrospective study, we collected all cases of CVST in SARS-CoV-2 infected patients admitted to nine tertiary stroke centers from the beginning of the pandemic to June 30th, 2020. We compared the demographics, clinical and radiological characteristics, risk factors, and outcome of these patients with a control group of non-SARS-CoV-2 infected CVST patients in the same seasonal period of the years 2012 –2016 from the country where the majority of cases were recruited.
Source: Journal of the Neurological Sciences - October 14, 2020 Category: Neurology Authors: Ashkan Mowla, Banafsheh Shakibajahromi, Shima Shahjouei, Afshin Borhani-Haghighi, Nasrin Rahimian, Humain Baharvahdat, Soheil Naderi, Fariborz Khorvash, Davar Altafi, Seyed Amir Ebrahimzadeh, Ghasem Farahmand, Alaleh Vaghefi Far, Vijay K. Sharma, Saeideh Source Type: research
Elevated fasting blood glucose is predictive of the severity and poor outcome in nondiabetic patients with cerebral venous thrombosis
Although elevated fasting blood glucose (FBG) at admission is associated with poor outcome in patients with ischemic and hemorrhagic stroke, it has not been investigated in patients with cerebral venous thrombosis (CVT). We aimed to determine the correlation between elevated FBG and severity and outcome among CVT patients.
Source: Journal of the Neurological Sciences - July 15, 2020 Category: Neurology Authors: Yating Wu, Lixin Zhou, Ming Yao, Yicheng Zhu, Jun Ni, Liying Cui, Bin Peng Source Type: research
Paradoxical embolism through a patent foramen ovale from central venous catheter thrombosis: A potential cause of stroke
Paradoxical embolism refers to a potential condition in which an embolus arising from a venous source crosses into the systemic circulation through a right-to-left cardiac shunt causing an arterial embolism.A 39-year-old woman carrier of a central venous catheter (CVC) without evident risk factors for stroke, developed an acute right homonymous hemianopia during hemodialysis. On neuroimaging, an infarct in the territory of the left posterior cerebral artery was demonstrated. Transesophageal echocardiography revealed a patent foramen ovale (PFO) and a large fluctuating thrombus in the right atrium on the tip of the CVC, thu...
Source: Journal of the Neurological Sciences - April 3, 2020 Category: Neurology Authors: Di Stefano Vincenzo, Di Fulvio Maria, Di Liberato Lorenzo, Onofrj Marco, De Angelis Maria Vittoria Tags: Clinical Short Communication Source Type: research
Impact of thrombus migration on clinical outcomes in patients with internal carotid artery occlusions and patent middle cerebral artery
Patency of the middle cerebral artery (MCA) in acute ischemic stroke with internal carotid artery (ICA) occlusions is associated with less severe stroke and favorable outcomes. However, thrombus migration to distal intracranial vessels may lead to unfavorable outcomes. We investigated the influence of thrombus migration on clinical outcomes in patients with ICA occlusions and patent MCA.
Source: Journal of the Neurological Sciences - February 14, 2020 Category: Neurology Authors: Junpei Koge, Shoji Matsumoto, Ichiro Nakahara, Akira Ishii, Taketo Hatano, Yujiro Tanaka, Daisuke Kondo, Jun-ichi Kira, Izumi Nagata Source Type: research
Atrial fibrillation, not atrial cardiopathy, is associated with stroke: A single center retrospective study
Atrial fibrillation (AF) increases the risk of thromboembolism. Atrial cardiopathy, defined as structural left atrial enlargement (LAE), has been proposed to be a unifying risk factor for stroke, with or without atrial fibrillation (AF). We sought to understand the relative importance of LAE and AF as risk factors for stroke.
Source: Journal of the Neurological Sciences - May 14, 2019 Category: Neurology Authors: Muhammad Affan, Abhimanyu Mahajan, Sumul Modi, Lonni Schultz, Angelos Katramados, Stephan A. Mayer, Daniel Miller Source Type: research
Whipple's endocarditis diagnosed by thrombus analysis retrieved by successful mechanical thrombectomy
We report a case of Whipple Endocarditis leading to a proximal embolic stroke successfully treated by mechanical thrombectomy.
Source: Journal of the Neurological Sciences - March 13, 2019 Category: Neurology Authors: Ong Elodie, Paul-Emile Labeyrie, Matthieu Aubry, Delahaye Cecile, Sandrine Roux, Tristan Ferry, Norbert Nighoghossian Tags: Letter to the Editor Source Type: research
Low-dose versus standard-dose intravenous alteplase for octogenerian acute ischemic stroke patients: A multicenter prospective cohort study
The optimal dose of alteplase for acute ischemic stroke among geriatric patients is unclear. We aimed to assess the efficacy and safety of a low-dose (0.6 mg/kg) and standard-dose (0.9 mg/kg) alteplase for varying severity of Asian geriatric stroke patients.
Source: Journal of the Neurological Sciences - January 29, 2019 Category: Neurology Authors: A-Ching Chao, Ke Han, Sheng-Feng Lin, Ruey-Tay Lin, Chih-Hung Chen, Lung Chan, Huey-Juan Lin, Yu Sun, Yung-Yang Lin, Po-Lin Chen, Shinn-Kuang Lin, Cheng-Yu Wei, Yu-Te Lin, Jiunn-Tay Lee, Han-Hwa Hu, Chyi-Huey Bai, On behalf of the Taiwan Thrombolytic Ther Source Type: research
