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Intravenous thrombolysis for acute ischaemic stroke in patients on direct oral anticoagulants
ConclusionsIn this expert opinion paper, it is suggested that IVT can be performed in patients selected according to the time elapsed since the drug was last taken, renal function, type of hospital where the patient is admitted and plasma concentration of DOAC.
Source: European Journal of Neurology - March 9, 2018 Category: Neurology Authors: E. Touz é, Y. Gruel, I. Gouin‐Thibault, E. De Maistre, S. Susen, P. Sie, L. Derex Tags: Original Article Source Type: research

Impact of anemia on in ‐hospital complications after ischemic stroke
ConclusionAnemia is an independent predictor of in‐hospital complications following stroke, especially for pneumonia, GIB and thromboembolism. Whether prophylaxis and treatment of anemia would prevent in‐hospital complications remains to be studied.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - February 12, 2018 Category: Neurology Authors: Chen ‐Chen Wei, Shu‐Ting Zhang, Ge Tan, Shi‐Hong Zhang, Ming Liu Tags: Original Article Source Type: research

Intravenous thrombolysis for acute ischaemic stroke in patients on direct oral anticoagulants Expert opinion of the Societe Francaise de Neurologie Vasculaire (SFNV) French Vascular Neurology Society and the Groupe Francais d'etudes sur l'Hemostase et la Thrombose (GFHT) French study Group on Haemostasis and Thrombosis
ConclusionsIn this expert opinion paper, we suggest that IVT can be performed in patients selected according to the time elapsed since the drug was last taken, renal function, type of hospital where the patient is admitted and plasma concentration of DOAC.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - January 23, 2018 Category: Neurology Authors: Emmanuel Touz é, Yves Gruel, Isabelle Gouin‐Thibault, Emmanuel De Maistre, Sophie Susen, Pierre Sie, Laurent Derex Tags: Original Article Source Type: research

The risk of ischaemic stroke in primary antiphospholipid syndrome patients: a prospective study
ConclusionsPatients with PAPS, including young patients, have a high risk of recurrent thrombosis despite anticoagulation treatment. A careful risk assessment is mandatory to identify patients at risk for recurrence.
Source: European Journal of Neurology - December 2, 2017 Category: Neurology Authors: M. Radin, K. Schreiber, I. Cecchi, D. Roccatello, M. J. Cuadrado, S. Sciascia Tags: Original Article Source Type: research

The risk of ischaemic stroke in primary APS patients: a prospective study
ConclusionsPatients with PAPS, including young patients, have a high risk of recurrent thrombosis despite anticoagulation treatment. A careful risk assessment is mandatory to identify patients at risk for recurrence.This article is protected by copyright. All rights reserved.
Source: European Journal of Neurology - October 30, 2017 Category: Neurology Authors: Massimo Radin, Karen Schreiber, Irene Cecchi, Dario Roccatello, Maria Jos é Cuadrado, Savino Sciascia Tags: Original Article Source Type: research

European Stroke Organization guideline for the diagnosis and treatment of cerebral venous thrombosis – endorsed by the European Academy of Neurology
ConclusionsMulticentre observational and experimental studies are needed to increase the level of evidence supporting recommendations on the diagnosis and management of CVT.
Source: European Journal of Neurology - August 20, 2017 Category: Neurology Authors: J. M. Ferro, M. ‐G. Bousser, P. Canhão, J. M. Coutinho, I. Crassard, F. Dentali, M. Minno, A. Maino, I. Martinelli, F. Masuhr, D. Aguiar de Sousa, J. Stam, Tags: Guidelines Source Type: research

Impact of intravenous thrombolysis on recanalization rates in patients with stroke treated with bridging therapy
ConclusionsRelevant recanalization after IVT and prior to EVT in patients receiving bridging therapy was highly dependent on the occlusion site. These findings suggest that future randomized controlled trials should consider occlusion site and treatment paradigm to specify patients who benefit most from bridging therapy in comparison to EVT or IVT alone.
Source: European Journal of Neurology - June 26, 2017 Category: Neurology Authors: L. Mueller, F. Pult, J. Meisterernst, M. R. Heldner, M. ‐L. Mono, R. Kurmann, M. Buehlmann, U. Fischer, H. P. Mattle, M. Arnold, P. Mordasini, J. Gralla, G. Schroth, M. El‐Koussy, S. Jung Tags: Original Article Source Type: research

Symptomatic post ‐thrombolytic intracerebral hemorrhage is not related to the cause of stroke
Conclusions The development of sICH in IVT‐treated patients is not related to the cause of stroke.
Source: European Journal of Neurology - August 31, 2016 Category: Neurology Authors: S. Curtze, G. Sibolt, S. Melkas, S. Mustanoja, E. Haapaniemi, J. Putaala, T. Sairanen, M. Tiainen, T. Tatlisumak, D. Strbian Tags: Original Article Source Type: research

Post ‐thrombolytic blood pressure and symptomatic intracerebral hemorrhage
ConclusionsPatients with post‐thrombolytic sICH have significantly higher systolic BP at several time‐points compared with patients without sICH.
Source: European Journal of Neurology - August 16, 2016 Category: Neurology Authors: T. Waltimo, E. Haapaniemi, I. L. Surakka, S. Melkas, T. Sairanen, G. Sibolt, T. Tatlisumak, D. Strbian Tags: Original Article Source Type: research

The syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis mimicking an acute stroke
ConclusionsThe decision to thrombolyse or perform an LP in HaNDL patients mimicking a stroke is difficult in the acute setting. Perfusion CT can provide misleading results and CTA may be useful in ruling out occlusion of a cerebral vessel.
Source: European Journal of Neurology - April 22, 2016 Category: Neurology Authors: M. Guillan, A. DeFelipe‐Mimbrera, A. Alonso‐Canovas, M. C. Matute, R. Vera, A. Cruz‐Culebras, N. Garcia‐Barragan, J. Masjuan Tags: Original Article Source Type: research

Extensive blooming artifact predicts no recanalization after intravenous thrombolysis
ConclusionsThe extent of SVS width beyond the lumen might reflect the content of hemosiderin. An extreme overestimation ratio might indicate aged thrombus, which may be resistant to thrombolysis.
Source: European Journal of Neurology - December 26, 2015 Category: Neurology Authors: S. Yan, Q. Chen, X. Zhang, M. Xu, Q. Han, A. Shao, D. S. Liebeskind, M. Lou Tags: Original Article Source Type: research

The diagnostic yield of transesophageal echocardiography in patients with cryptogenic cerebral ischaemia: a meta‐analysis
ConclusionRoutine TEE in patients with cryptogenic IS/TIA commonly identifies abnormal findings. However, the prevalence of cardiac conditions considered to be causally associated with cerebral ischaemia (intracardiac thrombi and tumors) is low.
Source: European Journal of Neurology - November 20, 2015 Category: Neurology Authors: A. H. Katsanos, S. Giannopoulos, A. Frogoudaki, A.‐R. Vrettou, I. Ikonomidis, I. Paraskevaidis, C. Zompola, K. Vadikolias, E. Boviatsis, J. Parissis, K. Voumvourakis, A. P. Kyritsis, G. Tsivgoulis Tags: Original Article Source Type: research

Susceptibility vessel sign on T2* magnetic resonance imaging and recanalization results of mechanical thrombectomy with stent retrievers: a multicentre cohort study
ConclusionsThe success of recanalization in acute stroke patients treated with stent retrievers was related to thrombus length but not to the presence of SVS.
Source: European Journal of Neurology - March 19, 2015 Category: Neurology Authors: S. Soize, A. L. Batista, C. Rodriguez Regent, D. Trystram, M. Tisserand, G. Turc, I. Serre, W. Ben Hassen, M. Zuber, D. Calvet, J.‐L. Mas, J.‐F. Meder, J. Raymond, L. Pierot, C. Oppenheim, O. Naggara Tags: Original Article Source Type: research

Recurrence of stroke amongst women of reproductive age: impact of and on subsequent pregnancies
ConclusionThe recurrence of stroke after pregnancy is very low, which should be considered when counseling these patients.
Source: European Journal of Neurology - February 1, 2015 Category: Neurology Authors: A. Cruz‐Herranz, I. Illán‐Gala, P. Martínez‐Sánchez, B. Fuentes, E. Díez‐Tejedor Tags: Original Article Source Type: research

Symptomatic intracranial haemorrhage after thrombolysis with adjuvant anticoagulation in basilar artery occlusion
ConclusionsThe risk of sICH was largely determined by extension of ischaemic changes on admission computed tomography. Clinically relevantly, also higher post‐thrombolytic SBP as described earlier and lower perithrombolytic platelet counts do increase the risk, a finding requiring confirmation in other patient series.
Source: European Journal of Neurology - December 1, 2014 Category: Neurology Authors: T. Sairanen, D. Strbian, R. Ruuskanen, H. Silvennoinen, O. Salonen, P. J. Lindsberg Tags: Original Article Source Type: research

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