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Many take anticoagulants and OTC supplements, which poses risk
FINDINGSNearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban also used  over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding. People taking these medications largely lacked knowledge of some potentially serious interactions.BACKGROUNDDirect-acting oral anticoagulants are the drug of choice for stroke prevention in patients with atrial fibrillation, which occurs most frequently in older patients. Apixaban is one of the most frequently prescribed. However, most people prescribed apix...
Source: UCLA Newsroom: Health Sciences - October 31, 2019 Category: Universities & Medical Training Source Type: news

Risk of ischemic stroke associated with non‐steroidal anti‐inflammatory drugs and paracetamol: a population‐based case‐control study
ConclusionsDiclofenac and aceclofenac increase the risk of ischemic stroke while ibuprofen and naproxen do not. Dose, duration and baseline CV risk, but not aspirin use, appear to modulate the risk. Paracetamol does not increase the risk, even in patients with a high background CV risk.
Source: Journal of Thrombosis and Haemostasis - February 24, 2015 Category: Hematology Authors: P. García‐Poza, F. J. Abajo, M. J. Gil, A. Chacón, V. Bryant, L. A. García‐Rodríguez Tags: Original Article Source Type: research

Risk of ischaemic stroke associated with non‐steroidal antiinflammatory drugs and paracetamol: a population‐based case‐control study
ConclusionsDiclofenac and aceclofenac increase the risk of ischaemic stroke while ibuprofen and naproxen do not. Dose, duration and baseline CV risk, but not aspirin use, appear to modulate the risk. Paracetamol does not increase the risk, even in patients at high background CV risk.This article is protected by copyright. All rights reserved.
Source: Journal of Thrombosis and Haemostasis - January 22, 2015 Category: Hematology Authors: Patricia García‐Poza, Francisco J. Abajo, Miguel J. Gil, Ana Chacón, Verónica Bryant, Luis A. García‐Rodríguez Tags: Original Article ‐ Cardiovascular Medicine Source Type: research

Risk of ischaemic stroke associated with non-steroidal antiinflammatory drugs and paracetamol: a population-based case-control study.
CONCLUSIONS: Diclofenac and aceclofenac increase the risk of ischaemic stroke while ibuprofen and naproxen do not. Dose, duration and baseline CV risk, but not aspirin use, appear to modulate the risk. Paracetamol does not increase the risk, even in patients at high background CV risk. This article is protected by copyright. All rights reserved. PMID: 25611553 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - January 22, 2015 Category: Hematology Authors: García-Poza P, de Abajo FJ, Gil MJ, Chacón A, Bryant V, García-Rodríguez LA Tags: J Thromb Haemost Source Type: research