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Date of birth and the incidence of acute ischemic stroke in Hungary
CONCLUSIONS: This, however, cannot be defined as a causal relationship if we consider the number of live births in 1949, as both measures change similarly during the year, as indicated by the strong positive correlation between thrombolysis frequency according to date of birth between 2007 and 2016 and the number of births in the 1949 census by month.PMID:36098448 | DOI:10.33588/rn.7506.2021479
Source: Revista de Neurologia - September 13, 2022 Category: Neurology Authors: A K B éres-Molnár R K Simonn é-Mátis N Al-Muhanna T Jarecsny E Dud ás D J ánoska M P álosi G Toldi A Folyovich Source Type: research

Christmas, acute ischemic stroke and stroke ‐related mortality in Hungary
ConclusionsThese findings may predominantly relate to emotional and psychological factors. In case of women, the anxiety secondary to festive preparations, while in men below 65  years, the increased psychological stress of providing financial security for the celebration may play an important role.
Source: Brain and Behavior - March 9, 2021 Category: Neurology Authors: Andr ás Folyovich, Réka Mátis, Nadim Al‐Muhanna, Tamás Jarecsny, Eszter Dudás, Dorottya Jánoska, Mihály Pálosi, Anna K. Béres‐Molnár, Gergely Toldi Tags: ORIGINAL RESEARCH Source Type: research

Daylight saving time and the incidence of thrombolysis to treat acute ischemic stroke.
CONCLUSIONS: Our findings reflect that psychosocial factors, such as the approach of the last day of the month override the intrinsic effect of disturbances of the circadian rhythm on stroke incidence. PMID: 32241570 [PubMed - as supplied by publisher]
Source: Revue Neurologique - April 4, 2020 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Intravenous Thrombolysis in Posterior Circulation Stroke
Conclusions: Up to date, no data about PCIS and IVT are available from RTCs. Based on limited results from retrospective clinical studies and case series, IVT is safer for use in PCIS than in ACIS. Patients with brainstem ischemia, vertebral artery occlusion, and absence of basilar or posterior cerebral artery occlusion could be considered for treatment with IVT even in borderline cases. Time to IVT in PCIS seems to be a less crucial factor than in ACIS. IVT for PCIS may be beneficial even after 4.5 h from symptom onset. Introduction History of Intravenous Thrombolysis—The Most Relevant Studies Intravenous...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Description of the First Cases with ADAMTS13 Mutations in Hungary
CONCLUSIONS:Clinical and molecular characterization of the first 5 Hungarian cases with ADAMTS13 mutations was presented. Compound heterozygous, damaging ADAMTS13 mutations with deficient plasma ADAMTS13 activity were associated with serious clinical consequences. In case of thrombotic microangiopathy in young patients with stroke, or HELLP syndrome, complete workup for ADAMTS13 activity and inhibitors is necessary, and genetic analysis should be considered. Three new ADAMTS13 mutations (c.1016_1017delCA, c.3199T>A , c.2839C>T) were identified and shown to be associated with decreased plasma ADAMTS13 activity.Disclos...
Source: Blood - November 21, 2018 Category: Hematology Authors: Reti, M., Sinkovits, G., Cseprekal, O., Csuka, D., Szilagyi, A., Farkas, Z., Klucsik, Z., Szederjesi, A., Wagner, L., Reusz, G., Kremer Hovinga, J. A., Rigo, J., Masszi, T., Prohaszka, Z. Tags: 311. Disorders of Platelet Number or Function Source Type: research

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