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Condition: Diabetes Type 1

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Total 409 results found since Jan 2013.

Intracranial hemorrhage in large vessel occlusion patients receiving endovascular thrombectomy with or without intravenous alteplase: a secondary analysis of the DIRECT-MT trial
Conclusions Our data showed that in the DIRECT-MT trial, alteplase did not increase overall ICH for large vessel occlusion patients treated with thrombectomy, but it increased the parenchymal hematoma rate.
Source: Journal of NeuroInterventional Surgery - September 15, 2023 Category: Neurosurgery Authors: Hu, X., Zhou, Y., Ospel, J., Yao, F., Liu, Y., Wang, H., Li, B., Hui, P., Yang, P., Zhang, Y., Zhang, L., Li, Z., Xing, P., Shi, H., Han, H., Wang, S., Fang, Q., Liu, J., for the Direct-MT investigators Tags: Open access, Ischemic stroke Source Type: research

Causal associations between type 1 diabetes mellitus and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: This MR study provided evidence supporting the causal effect of T1DM on peripheral atherosclerosis and coronary atherosclerosis, with hypertension partly mediating this effect.PMID:37659996 | PMC:PMC10475187 | DOI:10.1186/s12933-023-01974-6
Source: Atherosclerosis - September 2, 2023 Category: Cardiology Authors: Zirui Liu Haocheng Wang Zhengkai Yang Yu Lu Cao Zou Source Type: research

Limb and cardiovascular event risk in type 1 and 2 diabetic patients with peripheral artery disease
Conclusions: PAD patients with T1DM had a higher LE risk than those with T2DM, even after adjustment for glycemic control and pertinent risk factors, but CVE risk and all-cause mortality were equivocal. These data suggest a potential role for more intensive LE risk modification in PAD patients with T1DM, but further investigation is needed.PMID:37519117 | DOI:10.1024/0301-1526/a001086
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 31, 2023 Category: Surgery Authors: Daniel Sykora Christine Firth Marlene Girardo Andrew Tseng Paul Wennberg David Liedl Fadi Shamoun Source Type: research

Exploring the Causality of Type 1 Diabetes and Stroke Risk: A Mendelian Randomization Study and Meta-analysis
In conclusion, T1D was causally associated with SVS, but not with other subtypes of stroke. More investigation is needed to understand the underlying biology mechanism.PMID:37493922 | DOI:10.1007/s12035-023-03517-2
Source: Atherosclerosis - July 26, 2023 Category: Cardiology Authors: Xuelun Zou Le Zhang Leiyun Wang Sai Wang Yi Zeng Source Type: research

Polymorphonuclear phenotypical expression of CD18, at baseline and after in vitro activation, in several clinical disorders: Revision of our case series
CONCLUSIONS: in the different clinical disorders, the trend of this integrin subunit provides some specific information, useful to select the best therapeutic strategy in clinical practice.PMID:37482987 | DOI:10.3233/CH-231771
Source: Clinical Hemorheology and Microcirculation - July 24, 2023 Category: Hematology Authors: Gregorio Caimi Rosalia Lo Presti Caterina Carollo Maria Montana Melania Carlisi Source Type: research

Diabetes status and other factors as correlates of risk for thrombotic and thromboembolic events during SARS-CoV-2 infection: A nationwide retrospective case-control study using Cerner Real-World Data™
Conclusions Risk of TTE during COVID-19 illness is substantially higher in patients with diabetes. Further, risk for TTEs is higher in those with T1DM versus T2DM. Confirmation of increased diabetes-associated clotting risk in future studies may warrant incorporation of diabetes status into SARS-CoV-2 infection treatment algorithms.
Source: BMJ Open - July 9, 2023 Category: General Medicine Authors: Tallon, E. M., Gallagher, M. P., Staggs, V. S., Ferro, D., Murthy, D. B., Ebekozien, O., Kosiborod, M. N., Lind, M., Manrique-Acevedo, C., Shyu, C.-R., Clements, M. A. Tags: Open access, Diabetes and Endocrinology, COVID-19 Source Type: research