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Total 36 results found since Jan 2013.

Altered plasma levels of apixaban in major gastrointestinal tract surgery: A case report and review of the literature
We describe a case of suspected altered apixaban disposition in a patient with an upper gastrointestinal cancer resection treated with apixaban for non-valvular atrial fibrillation. Diagnosis of ischemic stroke for left hemiparesis was confirmed due to recent emergence of a hypodense area in the posterior capsular nucleus of ischemic reference in a context of binuclear capsular lacunar lesions. Thus, apixaban underexposure was suspected from anamnestic data and oral anticoagulation was switched to parenteral at the next scheduled dose for stroke recurrence. Before switching apixaban pharmacokinetic analysis was performed a...
Source: Clinical Biochemistry - July 14, 2023 Category: Biochemistry Authors: Giammarco Baiardi Alessia Cafaro Manuela Stella Michela Cameran Caviglia Maria Gabriella Poeta Giuliana Cangemi Francesca Mattioli Source Type: research

Altered plasma levels of apixaban in major gastrointestinal tract surgery: a case report and review of the literature
We describe a case of suspected altered apixaban disposition in a patient with an upper gastrointestinal cancer resection treated with apixaban for non-valvular atrial fibrillation. Diagnosis of ischemic stroke for left hemiparesis was confirmed due to recent emergence of a hypodense area in the posterior capsular nucleus of ischemic reference in a context of binuclear capsular lacunar lesions. Thus, apixaban underexposure was suspected from anamnestic data and oral anticoagulation was switched to parenteral at the next scheduled dose for stroke recurrence. Before switching apixaban pharmacokinetic analysis was performed a...
Source: Clinical Biochemistry - July 14, 2023 Category: Biochemistry Authors: Giammarco Baiardi Alessia Cafaro Manuela Stella Michela Cameran Caviglia Maria Gabriella Poeta Giuliana Cangemi Francesca Mattioli Source Type: research

Altered plasma levels of apixaban in major gastrointestinal tract surgery: A case report and review of the literature
We describe a case of suspected altered apixaban disposition in a patient with an upper gastrointestinal cancer resection treated with apixaban for non-valvular atrial fibrillation. Diagnosis of ischemic stroke for left hemiparesis was confirmed due to recent emergence of a hypodense area in the posterior capsular nucleus of ischemic reference in a context of binuclear capsular lacunar lesions. Thus, apixaban underexposure was suspected from anamnestic data and oral anticoagulation was switched to parenteral at the next scheduled dose for stroke recurrence. Before switching apixaban pharmacokinetic analysis was performed a...
Source: Clinical Biochemistry - July 14, 2023 Category: Biochemistry Authors: Giammarco Baiardi Alessia Cafaro Manuela Stella Michela Cameran Caviglia Maria Gabriella Poeta Giuliana Cangemi Francesca Mattioli Source Type: research

Altered plasma levels of apixaban in major gastrointestinal tract surgery: a case report and review of the literature
We describe a case of suspected altered apixaban disposition in a patient with an upper gastrointestinal cancer resection treated with apixaban for non-valvular atrial fibrillation. Diagnosis of ischemic stroke for left hemiparesis was confirmed due to recent emergence of a hypodense area in the posterior capsular nucleus of ischemic reference in a context of binuclear capsular lacunar lesions. Thus, apixaban underexposure was suspected from anamnestic data and oral anticoagulation was switched to parenteral at the next scheduled dose for stroke recurrence. Before switching apixaban pharmacokinetic analysis was performed a...
Source: Clinical Biochemistry - July 14, 2023 Category: Biochemistry Authors: Giammarco Baiardi Alessia Cafaro Manuela Stella Michela Cameran Caviglia Maria Gabriella Poeta Giuliana Cangemi Francesca Mattioli Source Type: research

Use of heparin calibrated anti-Xa assay for apixaban and rivaroxaban measurement in the context of regional telestroke activity
CONCLUSION: Our study makes unsuitable the use of a universal cut-off. In opposition to recommendations made by other publications, the UFH cut-offs must be adapted to the reagent used locally by the laboratory, and to the considered DOAC.PMID:37329142 | DOI:10.1684/abc.2023.1812
Source: Annales de Biologie Clinique - June 17, 2023 Category: Biochemistry Authors: C éline Delassasseigne Cl émentine Leroux Pauline Renou David Girard Anne Lafargue St éphane Morel Pierre Thomas Belotti Laurent Weinmann Source Type: research