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Effect of Standardized Perioperative Management on EEG Indexes and Nerve and Limb Functions of Patients with Acute Cerebral Infarction Undergoing Mechanical Thrombectomy
CONCLUSION: The standardized perioperative management is effective in patients with acute cerebral infarction who were treated with arteriovenous combined thrombolysis or mechanical thrombectomy, which can improve the neurological function and physical function of patients. However, the mechanical thrombectomy has a better improvement effect on the neurological function and physical function of patients, with the relatively better safety, thrombolytic effect, and long-term prognosis.PMID:36199820 | PMC:PMC9529457 | DOI:10.1155/2022/1686891
Source: Disease Markers - October 6, 2022 Category: Laboratory Medicine Authors: Yu Gong Jie Wang Source Type: research

Cardiac troponin and adverse outcomes in atrial fibrillation: A meta-analysis
Conclusions AF with cardiac troponin elevation was independently associated with increased risk of all-cause mortality and MACEs. Therefore, determination of troponin should be considered for risk stratification in AF.
Source: Clinica Chimica Acta - December 7, 2017 Category: Laboratory Medicine Source Type: research

Acquired Dysfibrinogenemia Caused by Autoantibody Inhibiting Fibrin Polymerization in a Patient with MELAS Syndrome and Bleeding Tendency.
We present a case of acquired dysfibrinogenemia caused by an autoantibody that inhibited fibrin polymerization in a patient previously diagnosed with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, stroke-like episodes). The patient showed prolonged PT, aPTT, and thrombin time. There was no factor deficiency but fibrinogen antigen and activity were decreased. ELISA for detection of fibrinogen antibodies were performed and IgG purified from the patient's plasma bound to fibrinogen more strongly than did control IgG, indicating the presence of a fibrinogen-specific antibody. Thrombin-mediated fibrin polymeriz...
Source: Annals of Clinical and Laboratory Science - November 30, 2016 Category: Laboratory Medicine Authors: Lee N, Kim JE, Yoo HJ, Gu J, Kim H, Chung J, Koh Y, Kim HK Tags: Ann Clin Lab Sci Source Type: research

The potential role of vascular endothelial growth factor as a new biomarker in severe intracerebral hemorrhage
ConclusionVEGF could be a new marker in ICH for severity.
Source: Journal of Clinical Laboratory Analysis - October 31, 2016 Category: Laboratory Medicine Authors: Jun Zheng, Jianping Sun, Liang Yang, Bin Zhao, Zhenzeng Fan Tags: Research Article Source Type: research

Anticoagulation Strategies for the Management of Postoperative Atrial Fibrillation
Patients undergoing thoracic and cardiac procedures are at the highest risk for postoperative atrial fibrillation (POAF). POAF is associated with poor short-term and long-term outcomes, including high rates of early and late stroke, and late mortality. Patients with POAF that persists for longer than 48 hours should be anticoagulated on warfarin. Three new oral anticoagulants are available for the treatment of nonvalvular atrial fibrillation and have been found to be as efficacious or superior to warfarin in the prevention of stroke in high-risk patients, with similar to lower rates of major bleeding, and lower rates of i...
Source: Clinics in Laboratory Medicine - July 21, 2014 Category: Laboratory Medicine Authors: Eric Anderson, Cornelius Dyke, Jerrold H. Levy Source Type: research