Filtered By:
Condition: Bleeding
Nutrition: Iron

This page shows you your search results in order of date.

Order by Relevance | Date

Total 21 results found since Jan 2013.

Using Aspirin Every Day May Cause Anemia in Seniors
A new study suggests regular aspirin use in older adults may pose a serious risk of anemia, adding to existing research that challenges the long-established recommendation to use aspirin as a preventative therapy for dangerous cardiac events. The results come just a year after a national independent task force updated formal recommendations in April 2022 cautioning those over the age of 60 against beginning a daily aspirin regimen. For decades, aspirin has been used like a vitamin by a sizable portion of America’s aging population. Research as far back as the 1950s showed a daily low dose of the anti-inflammatory me...
Source: TIME: Health - June 21, 2023 Category: Consumer Health News Authors: Haley Weiss Tags: Uncategorized Aging healthscienceclimate Source Type: news

Metal ion chelation enhances tissue plasminogen activator (tPA)-induced thrombolysis: an in vitro and in vivo study
AbstractStroke is the third leading cause of death in the United States and the leading cause of adult disability. Despite enormous research efforts including many clinical trials, tissue plasminogen activator (tPA) remains the only FDA-approved treatment for acute ischemic stroke. Unfortunately, only 1 –3% of stroke patients in the US receive this therapy because of the narrow time window and severe side effects for using tPA. The most deadly and damaging side effect is the risk of intracranial bleeding or hemorrhage. For that reason, the dose of tPA and its overall administration are under tigh t control, which may com...
Source: Journal of Thrombosis and Thrombolysis - November 10, 2021 Category: Hematology Source Type: research

Iron chelation suppresses secondary bleeding after intracerebral hemorrhage in angiotensin II-infused mice
CONCLUSION: Iron overload plays a key role in secondary bleeding after ICH in Ang II-induced hypertensive mice. Iron chelation during the process of Ang II-induced hypertension suppresses secondary bleeding after ICH.PMID:34346561 | DOI:10.1111/cns.13706
Source: CNS Neuroscience and Therapeutics - August 4, 2021 Category: Neuroscience Authors: Jie Wang Xiao-Qin Tang Min Xia Cheng-Cheng Li Chao Guo Hong-Fei Ge Yi Yin Bo Wang Wei-Xiang Chen Hua Feng Source Type: research

B-po03-151 left atrial appendage occlusion as alternative approach for stroke prevention in hereditary hemorrhagic telangiectasia patients with atrial fibrillation
In this study, we evaluate the safety and efficacy of left atrial appendage occlusion (LAAO) for stroke prevention in HHT.
Source: Heart Rhythm - July 28, 2021 Category: Cardiology Authors: Mohammed Alghammass, Jad Aldanaf, Elizabeth Dranow, Kevin Whitehead Source Type: research

Iron deficiency does not impair the outcome after elective coronary artery bypass and aortic valve procedures
ConclusionsThe majority of patients undergoing elective CABG or SAVR suffer from ID;  however, we found no significant differences in regard to MACCE and postoperative morbidity between ID and non‐ID patients.
Source: Journal of Cardiac Surgery - December 20, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Moritz B. Immohr, Yukiharu Sugimura, Hug Aubin, Philipp Rellecke, Udo Boeken, Artur Lichtenberg, Payam Akhyari Tags: ORIGINAL ARTICLE Source Type: research

Deferoxamine Treatment Prevents Post-Stroke Vasoregression and Neurovascular Unit Remodeling Leading to Improved Functional Outcomes in Type 2 Male Diabetic Rats: Role of Endothelial Ferroptosis
This study aimed to determine the impact of iron chelation with deferoxamine (DFX) on (1) cerebral vascularization patterns and (2) functional outcomes after stroke in control and diabetic rats. After 8  weeks of type 2 diabetes induced by a combination of high-fat diet and low-dose streptozotocin, male control and diabetic animals were subjected to thromboembolic middle cerebral artery occlusion (MCAO) and randomized to vehicle, DFX, or tPA/DFX and followed for 14 days with behavioral tests. Vas cular indices (vascular volume and surface area), neurovascular remodeling (AQP4 polarity), and microglia activation were meas...
Source: Translational Stroke Research - August 31, 2020 Category: Neurology Source Type: research

Things I know to be true 1 – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health life miracle Source Type: news

Things I know to be true – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health 3 principles life miracle Source Type: news

Pericytes in Hereditary Hemorrhagic Telangiectasia.
Authors: Galaris G, Thalgott JH, Lebrin FPG Abstract Hereditary hemorrhagic telangiectasia (HHT) is a genetic disorder characterized by multi-systemic vascular dysplasia affecting 1 in 5000 people worldwide. Individuals with HHT suffer from many complications including nose and gastrointestinal bleeding, anemia, iron deficiency, stroke, abscess, and high-output heart failure. Identification of the causative gene mutations and the generation of animal models have revealed that decreased transforming growth factor-β (TGF-β)/bone morphogenetic protein (BMP) signaling and increased vascular endothelial growth factor ...
Source: Advances in Experimental Medicine and Biology - June 1, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Associations of Anemia With Outcomes in Patients With Spontaneous Intracerebral Hemorrhage: A Meta-Analysis
Conclusions: Anemia on admission was associated with higher mortality and an increased risk of poor outcome in patients with ICH. However, the results were limited by the high heterogeneity of included studies. Prospective, multi-center or population-based, large sample cohort studies are needed in the future. Introduction Intracerebral hemorrhage (ICH) is the second most common cause of stroke and a highly lethal disease (1), which still lacks effective therapeutic interventions (2, 3). Although age, baseline ICH volume and neurological status on admission are well-known predictors of outcome of ICH (4), none of t...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Eggs May Be Bad for the Heart, a New Study Says —But There’s More to the Story
Conclusions about eggs based on available scientific evidence vary widely — in part because nutrition research is notoriously hard to conduct accurately. Despite the entrenched belief that eggs raise cholesterol, some studies have suggested that dietary cholesterol intake doesn’t necessarily translate to higher blood cholesterol. One study from last year found that people who ate an egg per day had lower rates of heart disease and bleeding stroke than people who did not eat them, and research from 2016 found that eggs didn’t have a strong effect on risk of coronary artery disease. Some researchers have su...
Source: TIME: Health - March 15, 2019 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized Diet/Nutrition Source Type: news