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Fatal adverse events of rivaroxaban combined with aspirin: an analysis using data from VigiBase
ConclusionsFatal AEs related to rivaroxaban combined with aspirin, including bleeding and ischemic events, have been reported mostly in the elderly, and sometimes involved medication errors. The fatal AEs mainly manifested as serious bleeding, and most of them occurred in patients with concurrent multiple risk factors. Monitoring coagulation during rivaroxaban treatment is recommended in very high-risk ASCVD populations, and attention should be paid to prevention of medication errors.
Source: European Journal of Clinical Pharmacology - July 1, 2022 Category: Drugs & Pharmacology Source Type: research

Taking high doses of fish oil supplements may 'increase the risk of stroke'
MANY people may take fish supplements as they are lauded for their health benefits, Indeed, many researchers suggest that people eat oily fish or take supplements for arthritis. Nonetheless, the Mayo Clinic warns taking high doses of fish oil supplements might increase the risk of bleeding and possibly increase the risk of stroke.
Source: Daily Express - Health - March 22, 2022 Category: Consumer Health News Source Type: news

Things I know to be true 1 – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health life miracle Source Type: news

Things I know to be true – We are all walking miracles
Back when I was child I genuinely believed that when my mother kissed my knee to make it better, she did actually do that. And as I grew older although that belief faded away in the light of the obvious ‘fact’ of the medical model, it never truly disappeared. Time and again I would reflect on what it meant to be healthy and when my own health challenges began in my mid-teens, some part of me always knew that my mother’s kiss held meaning. I remember being 16 years old and just about to sit ‘O’ levels, as they were then. I had been having a period for what must have been weeks and I was tired a...
Source: The Hysterectomy Association - June 25, 2020 Category: OBGYN Authors: Linda Parkinson-Hardman Tags: Health 3 principles life miracle Source Type: news

Many take anticoagulants and OTC supplements, which poses risk
FINDINGSNearly 98% percent of people prescribed direct-acting oral anticoagulants such as apixaban also used  over-the-counter products. Of those, 33% took at least one such product that, in combination with the anticoagulants, could cause dangerous internal bleeding. People taking these medications largely lacked knowledge of some potentially serious interactions.BACKGROUNDDirect-acting oral anticoagulants are the drug of choice for stroke prevention in patients with atrial fibrillation, which occurs most frequently in older patients. Apixaban is one of the most frequently prescribed. However, most people prescribed apix...
Source: UCLA Newsroom: Health Sciences - October 31, 2019 Category: Universities & Medical Training Source Type: news

Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease.
CONCLUSIONS: This is the most extensive systematic review of RCTs conducted to date to assess effects of increasing PUFA on cardiovascular disease, mortality, lipids or adiposity. Increasing PUFA intake probably slightly reduces risk of coronary heart disease and cardiovascular disease events, may slightly reduce risk of coronary heart disease mortality and stroke (though not ruling out harms), but has little or no effect on all-cause or cardiovascular disease mortality. The mechanism may be via TG reduction. PMID: 30484282 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - November 27, 2018 Category: General Medicine Authors: Abdelhamid AS, Martin N, Bridges C, Brainard JS, Wang X, Brown TJ, Hanson S, Jimoh OF, Ajabnoor SM, Deane KH, Song F, Hooper L Tags: Cochrane Database Syst Rev Source Type: research

Studies: Low-Dose Aspirin May Not Prevent Initial Heart Attack, Stroke
Taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, but the risks don’t outweigh the benefits for most other folks, major new research finds. Although it’s been used for more than a century, aspirin’s value in many situations is still unclear. The latest studies are some of the largest and longest to test this pennies-a-day blood thinner in people who don’t yet have heart disease or a blood vessel-related problem. One found that aspirin did not help prevent first strokes or heart attacks...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 27, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch aspirin Source Type: news

Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease.
CONCLUSIONS: This is the most extensive systematic review of RCTs conducted to date to assess effects of increasing PUFA on cardiovascular disease, mortality, lipids or adiposity. Increasing PUFA intake probably slightly reduces risk of coronary heart disease and cardiovascular disease events, may slightly reduce risk of coronary heart disease mortality and stroke (though not ruling out harms), but has little or no effect on all-cause or cardiovascular disease mortality. The mechanism may be via lipid reduction, but increasing PUFA probably slightly increases weight. PMID: 30019767 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 18, 2018 Category: General Medicine Authors: Abdelhamid AS, Martin N, Bridges C, Brainard JS, Wang X, Brown TJ, Hanson S, Jimoh OF, Ajabnoor SM, Deane KH, Song F, Hooper L Tags: Cochrane Database Syst Rev Source Type: research

New Cochrane health evidence challenges belief that omega 3 supplements reduce risk of heart disease, stroke or death
New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death.Omega 3 is a type of fat. Small amounts of omega 3 fats are essential for good health, and they can be found in the food that we eat. The main types of omega 3 fatty acids are; alpha ­linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).  ALA is normally found in fats from plant foods, such as nuts and seeds (walnuts and rapeseed are rich sources). EPA and DHA, collectively called long chain omega 3 fats, are naturally found in fatty fish, such as s...
Source: Cochrane News and Events - July 16, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Flow Performance of the CorWave LVAD Membrane Wave Pump
Implantable long-term blood pumps currently available or in development employ high speed rotary impellers. Use of these devices is currently limited due to relatively high rates of stroke, bleeding complications and infection. A new blood pump technology is under development inspired by the swimming motion of a fish. High frequency, low amplitude linear actuation creates a wave motion on a polymer membrane, gently pushing the blood through the pump. This approach offers a less damaging method for pumping blood, provides full physiologic pulsatility and can operate efficiently over a wide range of operating conditions.
Source: The Journal of Heart and Lung Transplantation - March 31, 2018 Category: Transplant Surgery Authors: C.N. Botterbusch, P. Monticone, L. Polverelli Source Type: research