Stroke RSS

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Source: Heart, Lung and Circulation
Condition: Bleeding

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Total 24 results found since Jan 2013.

Time Trends in Stroke Risk Management Among Patients With Atrial Fibrillation in Australia Between 2011 –2019
This study examined management among Australian patients between 2011 –2019.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: K. Giskes, N. Lowres, J. Orchard, K. Hyun, C. Hespe, B. Freedman Source Type: research

Outcomes Following Bleeding on Direct Oral Anticoagulants in Patients With Atrial Fibrillation at Liverpool Hospital
Direct oral anticoagulants (DOACs) are vital in atrial fibrillation (AF) stroke prevention. On-treatment bleeding has significant morbidity and mortality. Dabigatran is reversible with an available specific agent; however, the Factor-Xa-Inhibitor (FxaI) reversal-agent has limited availability.
Source: Heart, Lung and Circulation - July 1, 2023 Category: Cardiology Authors: Z. Wang, D. Nguyen, P. Motum, D. Hsu, S. Ng, S. Lo Source Type: research

Oral Anticoagulant Use in Patients With Atrial Fibrillation and Chronic Kidney Disease: A Review of the Evidence With Recommendations for Australian Clinical Practice
Chronic kidney disease is common in patients with atrial fibrillation (AF) and is associated with heightened risks of stroke/systemic embolisation and bleeding. In this review we outline the evidence for AF stroke prevention in kidney disease, identify current knowledge gaps, and give recommendations for anticoagulation at various stages of chronic kidney disease.Overall, anticoagulation is underused. Warfarin use becomes increasingly difficult with advancing kidney disease, with difficulty maintaining international normalised ratio (INR) in therapeutic range, increased risk of intracranial and fatal bleeding compared to n...
Source: Heart, Lung and Circulation - November 3, 2022 Category: Cardiology Authors: Christopher Hammett, Sunil V. Badve, Peter G. Kerr, Huyen A. Tran, Benjamin K. Dundon, Sidney Lo, Andrew Wong, Joanne E. Joseph, Jenny Deague, Vlado Perkovic Tags: Review Source Type: research

Predictors of New-Onset Atrial Tachyarrhythmias After Transcatheter Atrial Septal Defect Closure in Adults
This study investigated unknown risk factors for the development of new-onset ATA after transcatheter ASD closure in patients without a history of ATA.
Source: Heart, Lung and Circulation - April 13, 2021 Category: Cardiology Authors: Kotaro Miura, Mai Kimura, Atsushi Anzai, Takahide Arai, Takashi Kawakami, Shinsuke Yuasa, Kentaro Hayashida, Jin Endo, Hikaru Tsuruta, Yuji Itabashi, Akio Kawamura, Keiichi Fukuda, Hideaki Kanazawa Tags: Original Article Source Type: research

079 Assessing Arterial Pulsatility in Patients With Continuous Flow Left Ventricular Assist Device Support
An increasing number of end-stage heart failure patients are supported by continuous-flow Left Ventricular Assist Devices (cfLVADs) as a bridge to heart transplantation. In these patients, accurate assessment of arterial pulsatility remains a challenge because of diminished pulse pressure, which itself can be associated with adverse events such as gastrointestinal bleeding and stroke. Our study investigates the value of simultaneous arterial pressure and arterial flow velocity assessment in cfLVAD patients.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: A. Adji, S. Emmanuel, P. Jain, C. Hayward Source Type: research

824 Eligibility for Percutaneous Left Atrial Appendage (LAA) Closure: A Retrospective Study of Patients With Atrial Fibrillation With Haemorrhagic Events
Anticoagulation is recommended in patients with AF at risk of cardioembolic stroke. However, in patients with major bleeding events, anticoagulation is contraindicated. Such patients may be eligible for percutaneous LAA closure to reduce stroke risk.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: P. Lu, F. Ha, A. Shrestha, C. Fung, A. MacIsaac, L. Sanders, S. Palmer Source Type: research

240 Outcomes with Novel Oral Anticoagulants(NOACs) Bleeding in Atrial Fibrillation (AF) Patients at Liverpool Hospital – a Single Centre Experience
NOACs are widely used for AF stroke prevention but Factor-Xa-Inhibitor(FXaI) reversing agent is not widely available and expensive.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: D. Nguyen, G. Femia, P. Motum, D. Hsu, S. Ng, S. Lo Source Type: research

230 Machine Learning Models for Predicting Ischemic Stroke and Major Bleeding Risk in Patients with Atrial Fibrillation
Risk scores such as CHA2DS2-VASc and HAS-BLED are used to assess stroke and bleeding risk respectively and choose appropriate antithrombotic therapy in patients with atrial fibrillation (AF). The application of ML models may improve risk prediction and identification of potential risk factors.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: J. Lu, G. Dwivedi, F. Sanfilippo, M. Bennamoun, J. Hung, T. Briffa, F. Sohel, R. Hutchens, J. Stewart, B. Chow, B. McQuillan Source Type: research

708 Stroke Prevention by Non-vitamin K Oral Anticoagulant (NOAC) Agents in the Absence of Atrial Fibrillation: Meta-analysis of Randomized Controlled Trials
Anticoagulation to prevent stroke is a mainstay of atrial fibrillation (AF) management. Use of warfarin in sinus rhythm reduces stroke rates, but with an increase in bleeding. The efficacy and safety of NOACs has not been studied.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: K. Lander, P. Thakeria, A. Ha, S. Nayyar Source Type: research

Outcomes of Asian-Americans Implanted With Left Ventricular Assist Devices: An Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) Analysis
Studies have indicated differences between Asians and Whites in their propensity for stroke, coronary artery disease, heart failure, bleeding and thrombosis. We investigated whether Asian-Americans on durable left ventricular assist devices (LVADs) exhibit differential morbidity and mortality when compared to Whites.
Source: Heart, Lung and Circulation - December 8, 2019 Category: Cardiology Authors: Iosif Taleb, James Wever-Pinzon, Wenyan Wang, Antigone Koliopoulou, Elizabeth Dranow, Tao Yu, Lixue Yin, Stephen H. McKellar, Josef Stehlik, James C. Fang, Omar Wever-Pinzon, Craig H. Selzman, Stavros G. Drakos Tags: Original Article Source Type: research

Is Incorrect Anti-Coagulation Dosing Contributing to Ischaemic Stroke Burden? A Retrospective Single-Centre Study from Regional New South Wales, Australia
Background: Atrial fibrillation (AF) contributes to 30% of ischaemic stroke presentations. Low doses of anti-coagulants are often prescribed to prevent stroke but ameliorate bleeding risk.
Source: Heart, Lung and Circulation - June 23, 2019 Category: Cardiology Authors: P. Bamford, M. Ray, S. Cheruvu, M. Parkinson, C. Said, J. Trappel, J. Rogers Tags: 195 Source Type: research

Dealing With the Left Atrial Appendage for Stroke Prevention: Devices and Decision-Making
Left atrial appendage (LAA) device occlusion represents a major evolution in stroke prevention for atrial fibrillation (AF). Left atrial appendage device occlusion is now a proven strategy which provides long-term thromboembolic stroke prevention for patients with non-rheumatic AF. Evidence supports its benefit as an alternative to long-term anticoagulation while mitigating long-term bleeding risks and improving cardiovascular mortality. The therapy offers expanded options to physicians and patients negotiating stroke prevention (both primary and secondary prevention), but a good understanding of the risks and benefits is ...
Source: Heart, Lung and Circulation - May 16, 2017 Category: Cardiology Authors: Karen P. Phillips, Vince Paul Source Type: research

Left Atrial Appendage Closure in Patients with Contra-Indications to Anticoagulants
This study sought to evaluate the utility of LAA device occlusion alone without OAC in patients at high risk of stroke but at serious risk of bleeding.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: S. Kumar, V. Paul, R. Mahajan, J. Marangou, P. Waddy, D. Lau, H. Haqqani, P. Sanders Tags: 351 Source Type: research

10-year Australian Trends in Periprocedural Complications after PCI
We examined the incidence and predictors of bleeding, acute kidney injury (AKI) and stroke following PCI, and their impact on 30-day outcomes.
Source: Heart, Lung and Circulation - July 27, 2016 Category: Cardiology Authors: S. Biswas, N. Andrianopoulos, A. Brennan, A. Ajani, J. Lefkovits, R. Warren, S. Duffy, D. Clark, G. New, C. Hiew, C. Reid, D. Eccleston Tags: 379 Source Type: research

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