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Cancers, Vol. 15, Pages 3409: Research Attitude and Interest among Cancer Survivors with or without Cognitive Impairment
Conclusions: Participants with cancer and CI are open to research procedures and interventions that are traditionally less utilized, which may facilitate the discovery of the pathogenesis and interventions for cancer-related cognitive impairment (CRCI).
Source: Cancers - June 29, 2023 Category: Cancer & Oncology Authors: Ding Quan Ng Daniella Chan Munjal M. Acharya Joshua D. Grill Alexandre Chan Tags: Article Source Type: research

The Association Between Thymidylate Synthase Gene Polymorphisms and the Risk of Ischemic Stroke in Chinese Han Population
In conclusion: This study has shown that TS rs699517 and rs2790 were significantly related to ischemic stroke patients.PMID:37378701 | DOI:10.1007/s10528-023-10431-8
Source: Biochemical Genetics - June 28, 2023 Category: Genetics & Stem Cells Authors: Fuhua Yu Lei Shi Qianru Wang Xiaohui Xing Zhongchen Li Lei Hou Zhengshan Zhou Zengguang Wang Yilei Xiao Source Type: research

Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats
CONCLUSIONS: Overall, the XO inhibitor febuxostat exerted protective effects against NASH and atherosclerosis in SHRSP5/Dmcr rats.PMID:37376883 | DOI:10.32725/jab.2023.009
Source: Atherosclerosis - June 28, 2023 Category: Cardiology Authors: Mai Kakimoto Moe Fujii Ikumi Sato Koki Honma Hinako Nakayama Sora Kirihara Taketo Fukuoka Shang Ran Satoshi Hirohata Kazuya Kitamori Shusei Yamamoto Shogo Watanabe Source Type: research

Interaction between SIRT1 and non-coding RNAs in different disorders
SIRT1 is a member of the sirtuin family functioning in the process of removal of acetyl groups from different proteins. This protein has several biological functions and is involved in the pathogenesis of metabolic diseases, malignancy, aging, neurodegenerative disorders and inflammation. Several long non-coding RNAs (lncRNAs), microRNAs (miRNAs) and circular RNAs (circRNAs) have been found to interact with SIRT1. These interactions have been assessed in the contexts of sepsis, cardiomyopathy, heart failure, non-alcoholic fatty liver disease, chronic hepatitis, cardiac fibrosis, myocardial ischemia/reperfusion injury, diab...
Source: Frontiers in Genetics - June 27, 2023 Category: Genetics & Stem Cells Source Type: research

Determinants of self-rated health among elderly patients with hypertension: a cross-sectional analysis based on the Chinese longitudinal healthy longevity survey
CONCLUSION: The findings of this study provide evidence for the need to develop effective health promotion programs for the well-being of hypertensive patients.PMID:37337961 | DOI:10.1080/10641963.2023.2224942
Source: Clinical and Experimental Hypertension - June 20, 2023 Category: Cardiology Authors: Yang Zhou Yanjing Huang Aohua Zhang Guige Yin Hongjuan Hu Source Type: research

7 Myths About Cholesterol, Debunked
You may not recall every lab value from your last physical, but you probably remember one: Your cholesterol level. If it’s higher than ideal, you’re not alone. According to the U.S. Centers for Disease Control and Prevention, between 2015 and 2018, almost 12% of U.S. adults ages 20 and up had high total cholesterol, defined as above 240 mg/dL. The type that physicians mostly worry about is LDL (or “bad”) cholesterol, which is one component of that total. Why do doctors care so much about cholesterol? First, “it predicts risk,” says Dr. Jeffrey Berger, a cardiologist and director of the C...
Source: TIME: Health - June 19, 2023 Category: Consumer Health News Authors: Katherine Hobson Tags: Uncategorized freelance healthscienceclimate heart health Source Type: news

Alcohol consumption and risks of more than 200 diseases in Chinese men
Nat Med. 2023 Jun 8. doi: 10.1038/s41591-023-02383-8. Online ahead of print.ABSTRACTAlcohol consumption accounts for ~3 million annual deaths worldwide, but uncertainty persists about its relationships with many diseases. We investigated the associations of alcohol consumption with 207 diseases in the 12-year China Kadoorie Biobank of >512,000 adults (41% men), including 168,050 genotyped for ALDH2- rs671 and ADH1B- rs1229984 , with >1.1 million ICD-10 coded hospitalized events. At baseline, 33% of men drank alcohol regularly. Among men, alcohol intake was positively associated with 61 diseases, including 33 not defi...
Source: Cancer Control - June 8, 2023 Category: Cancer & Oncology Authors: Pek Kei Im Neil Wright Ling Yang Ka Hung Chan Yiping Chen Yu Guo Huaidong Du Xiaoming Yang Daniel Avery Shaojie Wang Canqing Yu Jun Lv Robert Clarke Junshi Chen Rory Collins Robin G Walters Richard Peto Liming Li Zhengming Chen Iona Y Millwood China Kadoo Source Type: research

Clinical characteristics, risk factors, and prognostic analyses of coronary small vessel disease: a retrospective cohort study of 986 patients
CONCLUSION: Compared to non-CSVD, CSVD was associated with more complex lesions, had worse revascularization efficacy, and a poorer prognosis.PMID:37259582 | DOI:10.1080/00325481.2023.2221110
Source: Postgraduate Medicine - June 1, 2023 Category: Internal Medicine Authors: Yue Chen Xiao Cui Liujun Jiang Xiaolei Xu Chaoyang Huang Qiwen Wang Source Type: research

Gender heterogeneity in the influencing factors for cerebral microbleeds in acute ischemic stroke patients
CONCLUSION: There are gender differences in the influencing factors for CMBs in AIS patients. Age, old LIs, and blood glucose are independent risk or protective factors for comorbid CMBs in female AIS patients, although they are not associated with the risk of developing CMBs in male AIS patients.PMID:37259500 | DOI:10.1080/03007995.2023.2219581
Source: Current Medical Research and Opinion - June 1, 2023 Category: Research Authors: Xin Guo Yuan Xing Zhenjie Teng Zhiyuan Shen Xiaosu Guo Peiyuan Lv Shujuan Tian Source Type: research