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Total 15499 results found since Jan 2013.

Aggressive LDL-C Lowering and the Brain: Impact on Risk for Dementia and Hemorrhagic Stroke: A Scientific Statement From the American Heart Association
The objective of this scientific statement is to evaluate contemporary evidence that either supports or refutes the conclusion that aggressive low-density lipoprotein cholesterol lowering or lipid lowering exerts toxic effects on the brain, leading to cognitive impairment or dementia or hemorrhagic stroke. The writing group used literature reviews, references to published clinical and epidemiology studies, clinical and public health guidelines, authoritative statements, and expert opinion to summarize existing evidence and to identify gaps in current knowledge. Although some retrospective, case control, and prospective lon...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - September 14, 2023 Category: Cardiology Authors: Larry B Goldstein Peter P Toth Jennifer L Dearborn-Tomazos Robert P Giugliano Benjamin J Hirsh Jessica M Pe ña Magdy H Selim Daniel Woo American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular and Source Type: research

Minimal Adherence Threshold to Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation to Reduce the Risk of Thromboembolism and Death: A Nationwide Cohort Study
ConclusionPoor adherence to NOACs is associated with increased risks of thromboembolism and all-cause mortality. The minimal adherence threshold should be ≥ 90%, preferably even ≥ 95%.
Source: Cardiovascular Drugs and Therapy - September 14, 2023 Category: Cardiology Source Type: research

Clot-based time attenuation curve as a novel imaging predictor of mechanical thrombectomy functional outcome in acute ischemia stroke
ConclusionsThrombus TAC on CTP were found to be a promising new imaging biomarker to predict the outcomes of MT in AIS.Clinical relevance statementThis study revealed that clot-based time attenuation curve based on admission perfusion CT could reflect the permeability and composition of thrombus and, also, provide valuable information to predict the clinical outcomes of mechanical thrombectomy in patients with acute ischemia stroke.Key Points• Two time-attenuation curves distributions achieved strong correlations (|r|= 0.627, p < 0.001) with histopathological results.• The unimodal time-attenuation curve was ...
Source: European Radiology - September 14, 2023 Category: Radiology Source Type: research

High-Sensitivity C-reactive Protein and Intracranial Arterial Stenosis Predicted Recurrent Stroke and Dependence or Death in Minor Stroke or Transient Ischemic Attack
CONCLUSION: Concomitant presence of increased hsCRP levels and ICAS was associated with increased risk of stroke recurrence and dependence or death in patients with minor ischemic stroke or transient ischemic attack.PMID:37704441 | DOI:10.5551/jat.64229
Source: Journal of Atherosclerosis and Thrombosis - September 13, 2023 Category: Cardiology Authors: Jiejie Li Yuesong Pan Mengxing Wang Xia Meng Jinxi Lin Zixiao Li Hao Li Yilong Wang Xingquan Zhao Liping Liu Yongjun Wang Source Type: research

Urinary Immunoglobulin G Is a Novel Biomarker for Atherosclerotic Burden in Mild Acute Ischemic Stroke Patients
CONCLUSION: In MAIS, urinary IgG was associated with both the presence of atherosclerosis and an unfavorable outcome at 90 days after stroke onset.PMID:37704430 | DOI:10.5551/jat.64230
Source: Journal of Atherosclerosis and Thrombosis - September 13, 2023 Category: Cardiology Authors: Teppei Komatsu Motohiro Okumura Hiroyuki Kida Masakazu Ozawa Masahiro Mimori Tatsushi Kokubu Junichiro Takahashi Sumire Kurihara Takahiro Maku Haruhiko Motegi Maki Takahashi Tomotaka Shiraishi Ryoji Nakada Shiho Akiyama Tomomichi Kitagawa Takeo Sato Hirok Source Type: research

Thoracic Aortic Plaque Burden and Prediction of Cardiovascular Events in Patients Undergoing 320-row Multidetector CT Coronary Angiography
CONCLUSIONS: We found that comprehensive non-invasive evaluation of TAPB and CAD has prognostic value in MACE risk stratification for suspected CAD patients undergoing CCTA.PMID:37704429 | DOI:10.5551/jat.64251
Source: Journal of Atherosclerosis and Thrombosis - September 13, 2023 Category: Cardiology Authors: Kenichiro Otsuka Hirotoshi Ishikawa Hiroki Yamaura Kana Hojo Yasushi Kono Kenei Shimada Noriaki Kasayuki Daiji Fukuda Source Type: research

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