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Condition: Thrombosis

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Total 15499 results found since Jan 2013.

Acute ischemic stroke: The role of emergency carotid endarterectomy in isolated extracranial internal carotid artery occlusion
CONCLUSIONS: Emergency CEA in isolated eICA occlusion has proved to be a safe and effective treatment option in selected patients. CT perfusion, imaging the ischemic penumbra and quantifying the tissue suitable for reperfusion, offers a valid support in the diagnostic-therapeutic workup. Indeed, we can infer that the area of the ischemic penumbra is directly proportional to the margin of clinical improvement after revascularization, supposing that the appropriate intervention timing is respect.PMID:37594376 | DOI:10.1177/17085381231192712
Source: Vascular - August 18, 2023 Category: Surgery Authors: Pierfilippo Acciarri Alice Camagni Maddalena Bressan Gladiol Zenunaj Ilaria Casetta Andrea Bernardoni Vincenzo Gasbarro Luca Traina Source Type: research

Sexual dimorphism in peripheral blood cell characteristics linked to recanalization success of endovascular thrombectomy in acute ischemic stroke
AbstractEndovascular thrombectomy (EVT) success to treat acute ischemic stroke varies with factors like stroke etiology and clot composition, which can differ between sexes. We studied if sex-specific blood cell characteristics (BCCs) are related to recanalization success. We analyzed electronic health records of 333 EVT patients from a single interve ntion center, and extracted 71 BCCs from the Sapphire flow cytometry analyzer. Through Sparse Partial Least Squares Discriminant Analysis, incorporating cross-validation and stability selection, we identified BCCs associated with successful recanalization (TICI 3) in ...
Source: Journal of Thrombosis and Thrombolysis - August 18, 2023 Category: Hematology Source Type: research

Relapse of nephrotic syndrome with unusual thromboembolic event: A case report
Key Clinical MessageMost children with nephrotic syndrome heal without any sequelae. However, rare life-threatening complications such as thromboembolism may occur in pediatric nephrotic syndrome and should be considered in those with a new-onset neurologic deficit.AbstractThe thromboembolism (TE) as a complication of nephrotic syndrome (NS) is rare and serious, and may involve renal, cerebral, pulmonary, or peripheral venous and/or arterial thrombosis. Here, we describe a 4.5-year-old male with a history of nephrotic syndrome, who developed hemorrhagic stroke in the territory of middle cerebral artery (MCA).
Source: Clinical Case Reports - August 17, 2023 Category: General Medicine Authors: Zahra Pournasiri, Seyedeh Masumeh Hashemi, Seyyedeh Narjes Ahmadizadeh, Bahareh Yaghmaei, Mitra Khalili, Azita Behzad, Amirali Soheili, Mahnaz Jamee Tags: CASE REPORT Source Type: research

Association of immune checkpoint inhibitors therapy with arterial thromboembolic events in cancer patients: A retrospective cohort study
CONCLUSION: ICI-treated patients may exhibit a higher risk of ATEs, especially after 1 year of treatment.PMID:37584246 | DOI:10.1002/cam4.6455
Source: Atherosclerosis - August 16, 2023 Category: Cardiology Authors: Jie Zhu Yue Chen Yuanlong Zhang Wei Wang Yujue Wang Zhuo Lu Yulin Zhang Haike Lei Dairong Li Bo Long Haixia Liu Source Type: research

PAD4-Induced NETosis Via Cathepsin G-Mediated Platelet-Neutrophil Interaction in ChAdOx1 Vaccine-Induced Thrombosis
CONCLUSIONS: Patients with VITT display enhanced thrombogenesis by PAD4-mediated NETs formation via cathepsin G-mediated platelet/neutrophil interaction.PMID:37586040 | DOI:10.1161/ATVBAHA.123.319522
Source: Arteriosclerosis, Thrombosis and Vascular Biology - August 16, 2023 Category: Cardiology Authors: Roberto Carnevale Martina Leopizzi Marcello Dominici Giulia d'Amati Simona Bartimoccia Cristina Nocella Vittoria Cammisotto Alessandra D'Amico Valentina Castellani Francesco Baratta Alessia Bertelli Alessio Arrivi Danilo Toni Manuela De Michele Pasquale P Source Type: research

Comparative outcomes associated with rivaroxaban versus warfarin use in elderly patients with atrial fibrillation or acute venous thromboembolism managed in the United States: a systematic review of observational studies
CONCLUSIONS: This systematic review supports findings from subgroup analyses of randomized controlled trials that, compared with warfarin, rivaroxaban is associated with generally neutral or positive effects on thrombosis and a mixed picture on bleeding outcomes in older adults with either NVAF or VTE treated in the United States.PMID:37584187 | DOI:10.1080/03007995.2023.2247988
Source: Current Medical Research and Opinion - August 16, 2023 Category: Research Authors: William L Baker Matthew S Roberts Youssef Bessada Kimberly S Caroti Veronica Ashton Brahim K Bookhart Craig I Coleman Source Type: research

In-thrombus thrombin secretion: a new diagnostic marker of atrial fibrillation in cryptogenic stroke
Isr Med Assoc J. 2022 Dec 1;25(12):853-854.ABSTRACTEndovascularly retrieved clots may be a potential resource for diagnosing stroke etiology. This method may influence secondary prevention treatment. We measure thrombin activity eluted by serially washing clots. We concluded that an assay measuring the change in thrombin in clots retrieved during acute stroke endovascular thrombectomy procedures may serve as a diagnostic marker of the origin of the clot. The suggested mechanism for these differences may be the clot location before its retrieval, with high blood flow causing thrombin washout in atherosclerotic clots, in con...
Source: The Israel Medical Association Journal - August 16, 2023 Category: General Medicine Authors: Ze'ev Itsekson Hayosh Eiman Abu Bandora Natalia Shelestovich Maya Nulman Mati Bakon Gal Yaniv Boris Khaitovitch Shmuel Balan Alexandra Gerasimova Tali Drori Stefan Mausbach Yvonne Schwammenthal Arnon Afek Joab Chapman Efrat Shavit Stein David Orion Source Type: research

Improvement of Functional Outcomes in Patients with Stroke who Received Alteplase for Over 15 Years: Japan Stroke Data Bank
CONCLUSIONS: We revealed that IVT implementation rates in patients with AIS increased, and the functional outcome in these patients improved over 15 years. Therefore, the Japanese IVT dissemination strategy is considered appropriate and effective.PMID:37587045 | DOI:10.5551/jat.64200
Source: Journal of Atherosclerosis and Thrombosis - August 16, 2023 Category: Cardiology Authors: Akiko Ishigami Kazunori Toyoda Michikazu Nakai Sohei Yoshimura Shinichi Wada Yusuke Sasahara Kazutaka Sonoda Kaori Miwa Junpei Koge Masayuki Shiozawa Yoshitaka Iwanaga Yoshihiro Miyamoto Jin Nakahara Norihiro Suzuki Shotai Kobayashi Kazuo Minematsu Masato Source Type: research

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