Filtered By:
Condition: Thrombosis

This page shows you your search results in order of relevance. This is page number 9.

Order by Relevance | Date

Total 15499 results found since Jan 2013.

Racial-Ethnic Disparities in Acute Stroke Care in the Florida-Puerto Rico Collaboration to Reduce Stroke Disparities Study Epidemiology
We examined race‐ethnic disparities in acute stroke performance metrics in a voluntary stroke registry among Florida and Puerto Rico Get With the Guidelines‐Stroke hospitals.Methods and ResultsSeventy‐five sites in the Florida Puerto Rico Stroke Registry (66 Florida and 9 Puerto Rico) recorded 58 864 ischemic stroke cases (2010–2014). Logistic regression models examined racial‐ethnic differences in acute stroke performance measures and defect‐free care (intravenous tissue plasminogen activator treatment, in‐hospital antithrombotic therapy, deep vein thrombosis prophylaxis, discharge antithrombotic therapy, a...
Source: JAHA:Journal of the American Heart Association - February 14, 2017 Category: Cardiology Authors: Sacco, R. L., Gardener, H., Wang, K., Dong, C., Ciliberti-Vargas, M. A., Gutierrez, C. M., Asdaghi, N., Burgin, W. S., Carrasquillo, O., Garcia-Rivera, E. J., Nobo, U., Oluwole, S., Rose, D. Z., Waters, M. F., Zevallos, J. C., Robichaux, M., Waddy, S. P., Tags: Epidemiology, Race and Ethnicity, Treatment, Cerebrovascular Disease/Stroke Original Research Source Type: research

Biomarker Application for Precision Medicine in Stroke
AbstractStroke remains one of the leading causes of long-term disability and mortality despite recent advances in acute thrombolytic therapies. In fact, the global lifetime risk of stroke in adults over the age of 25 is approximately 25%, with 24.9 million cases of ischemic stroke and 18.7 million cases of hemorrhagic stroke reported in 2015. One of the main challenges in developing effective new acute therapeutics and enhanced long-term interventions for stroke recovery is the heterogeneity of stroke, including etiology, comorbidities, and lifestyle factors that uniquely affect each individual stroke survivor. In this com...
Source: Translational Stroke Research - December 17, 2019 Category: Neurology Source Type: research

Multicentre collection of uniform data on patients hospitalised for transient ischaemic attack or stroke in the Philippines: the Philippine Neurological Association One Database-Stroke (PNA1DB-Stroke) protocol
Introduction For scientific advances to translate into improved patient outcomes, systems of care must be in place to facilitate delivery of care. There is scarce information on quality of care and clinical outcome in our stroke patients. We aim to collect uniform data from patients with first or recurrent transient ischaemic attack (TIA) or ischaemic or haemorrhagic stroke to determine in-patient caseload, patient profile, types of diagnostic and therapeutic procedures, outcomes and overall quality of care among patients hospitalised for acute stroke in the Philippines. Methods and analysis This multicentre observational...
Source: BMJ Open - May 24, 2022 Category: General Medicine Authors: Philippine Neurological Association One Database - Stroke, Disease Study Management Group, Gan, Alvarez, Canete, Co, Collantes, Escabillas, Hiyadan, Juangco, Lokin, Macrohon-Valdez, Punsalan, Sarapuddin, Picar, Pascual V Tags: Open access, Neurology Source Type: research

Postthrombolysis outcomes in acute ischemic stroke patients of Asian race‐ethnicity
ConclusionsOur data indicate that Asian patients derive benefit from thrombolytic therapy.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Nishant K. Mishra, Bernard P. L. Chan, Hock‐Luen Teoh, Chang‐Hui Meng, Kennedy R. Lees, Christopher Chen, Vijay K. Sharma, Tags: Research Source Type: research

Thrombolysis Despite Recent Stroke: A Case Series Brief Reports
Conclusions— In our center, we thrombolysed 6 patients despite recent stroke. Three patients had asymptomatic petechial hemorrhagic transformation within the area of subacute infarct, without apparent neurological worsening. Prospective studies are needed to explore the possible safety of tissue-type plasminogen activator in the context of previous subacute stroke in otherwise eligible patients.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Alhazzaa, M., Sharma, M., Blacquiere, D., Stotts, G., Hogan, M., Dowlatshahi, D. Tags: Acute Cerebral Infarction, Thrombolysis Brief Reports Source Type: research

Body mass index and acute ischemic stroke outcomes
ConclusionsBeing overweight or obese is associated with a better functional outcome and reduced mortality in patients of acute ischemic stroke. However, the definition of an ‘optimal’ body mass index, in relation to stroke outcomes, may be affected by age, gender, and use of thrombolytic therapy.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: M. Saini, M. Saqqur, A. Shuaib, Tags: Research Source Type: research

Unchanged Utilization of Endovascular Treatment in Acute Ischemic Stroke Patients in the post IMS-III era (P4.295)
Conclusion: Contrary to expectations, there has been no reduction in the utilization of endovascular treatment among acute ischemic stroke patients after IMS-III, MR RESCUE and SYNTHESIS EXPANSION results were published.Disclosure: Dr. Hassan has nothing to disclose. Dr. Bezzina has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Jones-Fullingim has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Tekle has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hassan, A., Bezzina, C., Malik, A., Jones-Fullingim, L., Sanchez, C., Tekle, W., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Treatment Source Type: research

Critical Early Thrombolytic and Endovascular Reperfusion Therapy for Acute Ischemic Stroke Victims: a Call for Adjunct Neuroprotection
This article has 3 main goals: (1) first to emphasize the utility and cost-effectiveness of rt-PA to treat stroke; (2) second to review the recent endovascular trials with respect to efficacy, safety, and cost-effectiveness as a stroke treatment; and (3) to further consider and evaluate strategies to develop novel neuroprotective drugs. A thesis will be put forth so that future stroke trials and therapy development can optimally promote recovery so that stroke victims can return to “normal” life.
Source: Translational Stroke Research - August 29, 2015 Category: Neurology Source Type: research

Partial MHC Constructs Treat Thromboembolic Ischemic Stroke Characterized by Early Immune Expansion
Abstract Inflammation and thrombosis are tightly linked, with inflammation contributing to thromboembolism and to stroke outcome. Thromboembolism is a frequent cause of ischemic stroke; yet, the most used occlusion mouse models of experimental stroke do not effectively replicate thromboembolism. Our group recently described a novel thromboembolic mouse model of stroke that successfully occludes the middle cerebral artery with high reproducibility. In the current study, we characterize the peripheral and local immune outcomes as well as the ischemic response to immune therapy in a clinically relevant mouse model of...
Source: Translational Stroke Research - December 1, 2015 Category: Neurology Source Type: research

Mechanisms and outcomes of stroke during pregnancy and the postpartum period: A cross-sectional study
Conclusion: Compared with nonpregnant women of the same age group, women with PAS had fewer vascular risk factors. Cerebral venous thrombosis and RCVS were more common in PAS, most of which occurred postpartum. These results provide further evidence for the unique pathophysiology of pregnancy-related stroke, raising important questions for future investigation.
Source: Neurology Clinical Practice - February 15, 2016 Category: Neurology Authors: Miller, E. C., Yaghi, S., Boehme, A. K., Willey, J. Z., Elkind, M. S. V., Marshall, R. S. Tags: Migraine, Stroke in young adults, All Cerebrovascular disease/Stroke, Subarachnoid hemorrhage Research Source Type: research

Ischemic Stroke and Risk of Venous Thromboembolism in the General Population: The Tromso Study Epidemiology
ConclusionsThe risk of VTE increased during the first 3 months after an ischemic stroke. The particularly high risk of provoked VTE suggests that additional predisposing factors, such as immobilization, potentiate the VTE risk in patients with ischemic stroke.
Source: JAHA:Journal of the American Heart Association - November 6, 2016 Category: Cardiology Authors: Rinde, L. B., Smabrekke, B., Mathiesen, E. B., Lochen, M.–L., Nȷolstad, I., Hald, E. M., Wilsgaard, T., Brakkan, S. K., Hansen, J.–B. Tags: Epidemiology, Risk Factors, Ischemic Stroke, Thrombosis Original Research Source Type: research

Stroke Center Care and Outcome: Results from the CSPPC Stroke Program
AbstractThe aim of this study was to assess the association between admission to stroke centers for acute ischemic stroke and complications and mortality during hospitalization in a Chinese population by means of an observational study using data from the China Stroke Center Data-Sharing Platform. We compared in-hospital complications and mortality for patients admitted with acute ischemic stroke (N = 13,236) between November 1, 2018 and December 31, 2018 at stroke center (SH) and non-stroke center (CH) hospitals using distance to hospitals as an instrumental variable to adjust for potential prehospital selection bias....
Source: Translational Stroke Research - September 7, 2019 Category: Neurology Source Type: research

Four Decades of Ischemic Penumbra and Its Implication for Ischemic Stroke
AbstractThe ischemic penumbra defined four decades ago has been the main battleground of ischemic stroke. The evolving ischemic penumbra concept has been providing insight for the development of vascular and cellular approaches as well as diagnostic tools for the treatment of ischemic stroke. rt-PA thrombolytic therapy to prevent the transition of ischemic penumbra to core has been approved for acute ischemic stroke within 3  h and was later recommended to extend to 4.5 h after symptom onset. Mechanical thrombectomy was introduced for the treatment of acute ischemic stroke with a therapeutic window of up to 24 h after s...
Source: Translational Stroke Research - July 5, 2021 Category: Neurology Source Type: research

Predictors of in‐hospital death and symptomatic intracranial hemorrhage in patients with acute ischemic stroke treated with thrombolytic therapy: Paul Coverdell Acute Stroke Registry 2008–2012
ConclusionsIn this study of acute ischemic stroke patients, older age, male gender, National Institutes of Health Stroke Scale score, history of myocardial infarction or coronary artery disease, and history of atrial fibrillation were associated with increased in‐hospital death among patients receiving intravenous tissue plasminogen activator. Among patients treated with intravenous tissue plasminogen activator, in‐hospital mortality and symptomatic intracerebral hemorrhage rates were similar between those treated within three‐hours of time last known to be well and those treated between three and 4·5 hours after this time.
Source: International Journal of Stroke - September 12, 2013 Category: Neurology Authors: Xin Tong, Mary G. George, Quanhe Yang, Cathleen Gillespie Tags: Research Source Type: research

Is air transport of stroke patients faster than ground transport? A prospective controlled observational study
Conclusions We found significantly shorter time from contact to triaging neurologist to arrival in the regional stroke centre if stroke patients were transported by primarily dispatched ground ambulance compared with a secondarily dispatched helicopter.
Source: Emergency Medicine Journal - March 12, 2014 Category: Emergency Medicine Authors: Hesselfeldt, R., Gyllenborg, J., Steinmetz, J., Do, H. Q., Hejselbaek, J., Rasmussen, L. S. Tags: Stroke, Radiology, Clinical diagnostic tests Original article Source Type: research