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Condition: Hemorrhagic Stroke

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Total 10535 results found since Jan 2013.

Blood Pressure-Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke Brief Reports
Conclusions— There was no evidence that blood pressure–lowering treatment with candesartan is beneficial during the first week of hemorrhagic stroke. Instead, there were signs that such treatment may be harmful, but this needs to be verified in larger studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jusufovic, M., Sandset, E. C., Bath, P. M. W., Berge, E., on behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Brief Reports Source Type: research

Enrollment Yield and Reasons for Screen Failure in a Large Prehospital Stroke Trial Brief Reports
Conclusions— In this large, multicenter prehospital trial, nearly 40% of every calls from the field to physician-investigators resulted in trial enrollments. The most common reasons for nonenrollment were out of window last known well time, prestroke confounding medical condition, and absence of a consent provider. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00059332.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Kim, D.-H., Saver, J. L., Starkman, S., Liebeskind, D. S., Ali, L. K., Restrepo, L., Kim-Tenser, M., Valdes-Sueiras, M., Eckstein, M., Pratt, F., Stratton, S., Hamilton, S., Conwit, R., Sanossian, N., on behalf of the Field Administration of Stroke Therap Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke, Neuroprotectants Brief Reports Source Type: research

Smoking-Thrombolysis Relationship Depends on Ischemic Stroke Subtype Clinical Sciences
Conclusions— In patients treated with intravenous thrombolysis, smoking could be related to a better chance of functional independence if their subtype of stroke was noncardioembolic, and a lower risk of symptomatic intracranial hemorrhage and mortality in those with large artery atherosclerosis.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Tong, X., Wang, C., Liao, X., Pan, Y., Yan, H., Cao, Y., Liu, L., Zheng, H., Zhao, X., Wang, C., Li, H., Wang, D., Wang, Y., Wang, Y., on behalf of the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China) Investigators* Tags: Clinical Studies, Risk Factors, Pharmacology, Treatment, Ischemic Stroke Clinical Sciences Source Type: research

North American SOLITAIRE Stent-Retriever Acute Stroke Registry: Choice of Anesthesia and Outcomes Clinical Sciences
Conclusions— The NASA Registry has demonstrated that clinical outcomes and survival are significantly better in patients treated with LA, without increased symptomatic intracranial hemorrhage risk. Future trials should prospectively evaluate the effect of GA on outcomes.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Abou-Chebl, A., Zaidat, O. O., Castonguay, A. C., Gupta, R., Sun, C.-H. J., Martin, C. O., Holloway, W. E., Mueller-Kronast, N., English, J. D., Linfante, I., Dabus, G., Malisch, T. W., Marden, F. A., Bozorgchami, H., Xavier, A., Rai, A. T., Froehler, M. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research

Sleep Duration and Risk of Stroke Mortality Among Chinese Adults: Singapore Chinese Health Study Clinical Sciences
Conclusions— Both short and long sleep durations are associated with increased risk of stroke mortality in a Chinese population, particularly among those with a history of hypertension.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Pan, A., De Silva, D. A., Yuan, J.-M., Koh, W.-P. Tags: Behavioral/psychosocial - stroke, Cerebrovascular disease/stroke, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Long-Term Risk and Predictors of Recurrent Stroke Beyond the Acute Phase Brief Reports
Conclusions— Despite declining recurrence rates in this relatively young stroke population, almost one third are either dead or have experienced a second stroke in 5 years.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Pennlert, J., Eriksson, M., Carlberg, B., Wiklund, P.-G. Tags: Risk Factors for Stroke, Epidemiology Brief Reports Source Type: research

Safety of Thrombolysis in Patients With Acute Ischemic Stroke and Cerebral Cavernous Malformations Brief Reports
Conclusions— Given the limitations of our study (mainly low number of patients with CCM), the risk of thrombolysis-associated hemorrhage in patients with CCM remains uncertain. Although our data do not suggest an increased hazard from thrombolysis in patients with CCM, larger studies are necessary to determine definitively the influence of CCMs on parenchymal hemorrhage and symptomatic intracerebral hemorrhage.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Erdur, H., Scheitz, J. F., Tutuncu, S., Fiebach, J. B., Endres, M., Werring, D. J., Nolte, C. H. Tags: Acute Cerebral Infarction, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Emergency treatment of Stroke, Intracerebral Hemorrhage, Thrombolysis Brief Reports Source Type: research

Endoglin Deficiency Impairs Stroke Recovery Basic Sciences
Conclusions— Endoglin deficiency impairs brain injury recovery. Reduced angiogenesis, impaired macrophage homing, and delayed inflammation resolution could be the underlying mechanism.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Shen, F., Degos, V., Chu, P.-L., Han, Z., Westbroek, E. M., Choi, E.-J., Marchuk, D., Kim, H., Lawton, M. T., Maze, M., Young, W. L., Su, H. Tags: Cerebrovascular disease/stroke, Animal models of human disease, Genetically altered mice, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage Basic Sciences Source Type: research

Race/Ethnic Differences in the Risk of Hemorrhagic Complications Among Patients With Ischemic Stroke Receiving Thrombolytic Therapy Clinical Sciences
Conclusions— In patients with stroke receiving tPA, hemorrhagic complications were slightly higher in blacks and Asians, but not in Hispanics compared with whites. Asians also faced significantly higher risk for sICH relative to other race/ethnic groups. Future studies are needed to evaluate whether reduction in tPA dose similar to that used in many Asian countries could improve the safety of tPA therapy in Asians in the United States with acute ischemic strokes while maintaining efficacy.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Mehta, R. H., Cox, M., Smith, E. E., Xian, Y., Bhatt, D. L., Fonarow, G. C., Peterson, E. D., for the Get With The Guidelines-Stroke Program Tags: Thrombolysis Clinical Sciences Source Type: research

Standard-Dose Intravenous Tissue-Type Plasminogen Activator for Stroke Is Better Than Low Doses Clinical Sciences
Conclusions— Our study suggests that standard-dose intravenous tPA for stroke had more favorable outcome without increasing the risk of symptomatic intracranial hemorrhage than low-dose tPA. For Asian people, 0.9 mg/kg should be the optimal dose of tPA to treat acute ischemic stroke.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Liao, X., Wang, Y., Pan, Y., Wang, C., Zhao, X., Wang, D. Z., Wang, C., Liu, L., Wang, Y., on behalf of the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China Investigators Tags: Acute Cerebral Infarction, Thrombolysis Clinical Sciences Source Type: research

Different Doses of Recombinant Tissue-Type Plasminogen Activator for Acute Stroke in Chinese Patients Clinical Sciences
Conclusions— These results did not support the dose of 0.9 mg/kg of r-tPA being optimal for all patients in the East Asian population. In elderly patients (71–80 years), a lower dose of 0.6 mg/kg is associated with a better outcome. Confirmation of the results through randomized trial is required.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Chao, A.-C., Liu, C.-K., Chen, C.-H., Lin, H.-J., Liu, C.-H., Jeng, J.-S., Hu, C.-J., Chung, C.-P., Hsu, H.-Y., Sheng, W.-Y., Hu, H.-H., on behalf of the Taiwan Thrombolytic Therapy for Acute Ischemic Stroke (TTT-AIS) Study Group Tags: Thrombolysis Clinical Sciences Source Type: research

Combined Effects of Socioeconomic Position, Smoking, and Hypertension on Risk of Ischemic and Hemorrhagic Stroke Clinical Sciences
Conclusions— Reducing smoking in those with low socioeconomic position and in those with hypertension could potentially reduce social inequality stroke incidence.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Nordahl, H., Osler, M., Frederiksen, B. L., Andersen, I., Prescott, E., Overvad, K., Diderichsen, F., Rod, N. H. Tags: Behavioral/psychosocial - stroke, Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Epidemiology Clinical Sciences Source Type: research

Thrombolysis in Ischemic Stroke Without Arterial Occlusion at Presentation Clinical Sciences
Conclusions— This study provides crucial data that patients with ischemic stroke who do not have visible arterial occlusion at presentation may benefit from thrombolysis.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Lahoti, S., Gokhale, S., Caplan, L., Michel, P., Samson, Y., Rosso, C., Limaye, K., Hinduja, A., Singhal, A., Ali, S., Pettigrew, L. C., Kryscio, R., Dedhia, N., Hastak, S., Liebeskind, D. S. Tags: Cerebral Lacunes, Embolic stroke, Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke, Thrombolysis Clinical Sciences Source Type: research

Defining Clinically Relevant Cerebral Hemorrhage After Thrombolytic Therapy for Stroke: Analysis of the National Institute of Neurological Disorders and Stroke Tissue-Type Plasminogen Activator Trials Clinical Sciences
Conclusions— The ECASS2 and mSITS-MOST symptomatic intracerebral hemorrhage definitions, which combine radiological features and occurrence of substantial early neurological deterioration, best identify tPA hemorrhages that alter final patient outcome.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Rao, N. M., Levine, S. R., Gornbein, J. A., Saver, J. L. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Intracerebral Hemorrhage, Thrombolysis Clinical Sciences Source Type: research

Potassium Intake and Risk of Stroke in Women With Hypertension and Nonhypertension in the Women's Health Initiative Clinical Sciences
Conclusions— High potassium intake is associated with a lower risk of all stroke and ischemic stroke, as well as all-cause mortality in older women, particularly those who are not hypertensive.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Seth, A., Mossavar-Rahmani, Y., Kamensky, V., Silver, B., Lakshminarayan, K., Prentice, R., Van Horn, L., Wassertheil-Smoller, S. Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Epidemiology Clinical Sciences Source Type: research

Impact of Living Alone on the Care and Outcomes of Patients With Acute Stroke Brief Reports
Conclusions— Patients living alone had delayed hospital arrival, less thrombolytic therapy, and were less likely to return home. Greater understanding of the inter-relationships among living alone, social isolation, access to stroke care, and outcomes is needed.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Reeves, M. J., Prager, M., Fang, J., Stamplecoski, M., Kapral, M. K. Tags: Acute Stroke Syndromes Brief Reports Source Type: research

Validity of Hospital Discharge Diagnosis Codes for Stroke: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— A new AHA/ASA discharge code grouping to identify stroke had similar PPV and lower sensitivity compared with an alternative code grouping. Accuracy varied by patient characteristics and study sites.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jones, S. A., Gottesman, R. F., Shahar, E., Wruck, L., Rosamond, W. D. Tags: Cerebrovascular disease/stroke, Epidemiology Clinical Sciences Source Type: research

Ethnic Disparities in Ischemic Stroke, Intracerebral Hemorrhage, and Subarachnoid Hemorrhage Incidence in The Netherlands Clinical Sciences
Conclusions— Our findings suggest that Surinamese have an increased risk, whereas Moroccans have a reduced risk for all the various stroke subtypes. Among other ethnic minorities, the risk seems to depend on the stroke subtype and sex. These findings underscore the need to identify the root causes of these ethnic differences to assist primary and secondary prevention efforts.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Agyemang, C., van Oeffelen, A. A. M., Norredam, M., Kappelle, L. J., Klijn, C. J. M., Bots, M. L., Stronks, K., Vaartjes, I. Tags: Cerebrovascular disease/stroke Clinical Sciences Source Type: research

Derivation and External Validation of a Case Mix Model for the Standardized Reporting of 30-Day Stroke Mortality Rates Clinical Sciences
Conclusions— We have derived and externally validated 2 models to predict mortality in unselected patients with acute stroke using commonly collected clinical variables. In settings where the ability to record the full NIHSS on admission is limited, the level of consciousness component of the NIHSS provides a good approximation of the full NIHSS for mortality prediction.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Bray, B. D., Campbell, J., Cloud, G. C., Hoffman, A., James, M., Tyrrell, P. J., Wolfe, C. D. A., Rudd, A. G., on behalf of the Intercollegiate Stroke Working Party Group Tags: Epidemiology Clinical Sciences Source Type: research

Long-Term Costs of Stroke Using 10-Year Longitudinal Data From the North East Melbourne Stroke Incidence Study Clinical Sciences
Conclusions— Costs to 10 years after stroke have not previously been reported. Our findings demonstrate the importance of estimating resource use over longer periods for forecasting lifetime estimates.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Gloede, T. D., Halbach, S. M., Thrift, A. G., Dewey, H. M., Pfaff, H., Cadilhac, D. A. Tags: Health policy and outcome research, Other Stroke Treatment - Medical, Epidemiology Clinical Sciences Source Type: research

Hemorrhagic Stroke and Cerebral Paragonimiasis Brief Reports
Conclusions— Hemorrhagic stroke typically occurred during the acute stage and in the early stages of further Paragonimus migration. Delay of treatment increased the risk of initial and recurrent stroke.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Xia, Y., Ju, Y., Chen, J., You, C. Tags: Acute Cerebral Hemorrhage, Computerized tomography and Magnetic Resonance Imaging, Primary and Secondary Stroke Prevention, Risk Factors for Stroke Brief Reports Source Type: research

Randomized Controlled Trial of Early Rehabilitation After Intracerebral Hemorrhage Stroke: Difference in Outcomes Within 6 Months of Stroke Major Clinical Trial
Conclusions— For the first time, we have shown that commencing rehabilitation within 48 hours of intracerebral hemorrhage improves survival and functional outcomes at 6 months after stroke in hospitalized patients in China. Clinical Trial Registration— URL: http://www.chictr.org/en. Unique identifier: ChiCTR-TRC-13004039.
Source: Stroke - November 24, 2014 Category: Neurology Authors: Liu, N., Cadilhac, D. A., Andrew, N. E., Zeng, L., Li, Z., Li, J., Li, Y., Yu, X., Mi, B., Li, Z., Xu, H., Chen, Y., Wang, J., Yao, W., Li, K., Yan, F., Wang, J. Tags: Acute Cerebral Hemorrhage, Intracerebral Hemorrhage, Rehabilitation, Stroke Major Clinical Trial Source Type: research

Influence of Age on Clinical and Revascularization Outcomes in the North American Solitaire Stent-Retriever Acute Stroke Registry Clinical Sciences
Conclusion— Greater than 80 years of age is predictive of poor clinical outcome and increased mortality compared with younger patients in the NASA registry. However, intravenous tissue-type plasminogen activator use, lower NIHSS, and shorter revascularization time are associated with better outcomes. Further studies are needed to understand the endovascular therapy role in this cohort compared with medical therapy.
Source: Stroke - November 24, 2014 Category: Neurology Authors: Castonguay, A. C., Zaidat, O. O., Novakovic, R., Nguyen, T. N., Taqi, M. A., Gupta, R., Sun, C.-H. J., Martin, C., Holloway, W. E., Mueller-Kronast, N., E. English, J., Linfante, I., Dabus, G., Malisch, T. W., Marden, F. A., Bozorgchami, H., Xavier, A., R Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Off-Hours Admission and Acute Stroke Care Quality: A Nationwide Study of Performance Measures and Case-Fatality Clinical Sciences
Conclusion— Patients admitted off-hours received a poorer quality of care. However, the admission time–related differences in care were substantially reduced over time, and the differences in 30 days case-fatality appeared primarily to be explained by differences in stroke severity.
Source: Stroke - November 24, 2014 Category: Neurology Authors: Kristiansen, N. S., Mainz, J., Norgard, B. M., Bartels, P. D., Andersen, G., Johnsen, S. P. Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction Clinical Sciences Source Type: research

Autologous bone marrow mononuclear cells intrathecal transplantation in chronic stroke.
This study demonstrates the potential of autologous BMMNCs intrathecal transplantation in improving the prognosis of functional recovery in chronic stage of stroke. Further clinical trials are recommended. This trial is registered with NCT02065778. PMID: 25126443 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Predictors of in-hospital mortality for stroke in douala, cameroon.
Conclusion. The clinician should systematically diagnose and treat infectious states and hyperglycaemia in stroke. PMID: 24724038 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Reducing haemorrhagic transformation after thrombolysis for stroke: a strategy utilising minocycline.
Authors: Blacker DJ, Prentice D, Alvaro A, Bates TR, Bynevelt M, Kelly A, Kho LK, Kohler E, Hankey GJ, Thompson A, Major T Abstract Haemorrhagic transformation (HT) of recently ischaemic brain is a feared complication of thrombolytic therapy that may be caused or compounded by ischaemia-induced activation of matrix metalloproteinases (MMPs). The tetracycline antibiotic minocycline inhibits matrix MMPs and reduces macroscopic HT in rodents with stroke treated with tissue plasminogen activator (tPA). The West Australian Intravenous Minocycline and TPA Stroke Study (WAIMATSS) aims to determine the safety and efficacy ...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

The impact of experimental preconditioning using vascular endothelial growth factor in stroke and subarachnoid hemorrhage.
Authors: Eicker SO, Hoppe M, Etminan N, Macht S, Perrin J, Steiger HJ, Hänggi D Abstract Vascular endothelial growth factor (VEGF) stimulating angiogenesis was shown to be a potential novel therapeutic approach for the treatment of ischemic vascular diseases. The goal of the present study was to examine whether transfection of VEGF before occurrence of major stroke (part I) and cerebral vasospasm after experimental subarachnoid hemorrhage (SAH; part II) develops neuroprotective qualities. A total of 25 (part I) and 26 (part II) brains were analyzed, respectively. In part one, a significant reduction of infarct vol...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Intraluminal Thrombus, Intraplaque Hemorrhage, Plaque Thickness, and Current Smoking Optimally Predict Carotid Stroke Clinical Sciences
Conclusions— After excluding patients with noncarotid plaque stroke sources, optimal discrimination of carotid-source stroke was obtained with intraluminal thrombus, IPH, plaque thickness, and smoking history but not ulceration and stenosis.
Source: Stroke - December 22, 2014 Category: Neurology Authors: McNally, J. S., McLaughlin, M. S., Hinckley, P. J., Treiman, S. M., Stoddard, G. J., Parker, D. L., Treiman, G. S. Tags: CT and MRI, Carotid Stenosis, Embolic stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Body Mass Index and Stroke Risk Among Patients With Type 2 Diabetes Mellitus Clinical Sciences
Conclusions— The present study demonstrates an inverse association between BMI and stroke risk among patients with type 2 diabetes mellitus.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Li, W., Katzmarzyk, P. T., Horswell, R., Zhang, Y., Zhao, W., Wang, Y., Johnson, J., Hu, G. Tags: Obesity, Type 2 diabetes, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Subjective Memory Complaints and the Risk of Stroke Clinical Sciences
Conclusions— Subjective memory complaints might be an early indicator of stroke risk, especially in highly educated individuals.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Sajjad, A., Mirza, S. S., Portegies, M. L. P., Bos, M. J., Hofman, A., Koudstaal, P. J., Tiemeier, H., Ikram, M. A. Tags: Cerebrovascular disease/stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Symptomatic Carotid Atherosclerotic Disease: Correlations Between Plaque Composition and Ipsilateral Stroke Risk Clinical Sciences
Conclusions— Features of the vulnerable carotid plaque, including plaque thrombus, low fibrous content, macrophage infiltration, and microvessel density, correlate with predicted stroke risk. This study provides a basis for plaque imaging studies focused on stroke risk stratification.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Howard, D. P. J., van Lammeren, G. W., Rothwell, P. M., Redgrave, J. N., Moll, F. L., de Vries, J.-P. P. M., de Kleijn, D. P. V., den Ruijter, H. M., de Borst, G. J., Pasterkamp, G. Tags: Pathophysiology, Carotid Stenosis, Primary and Secondary Stroke Prevention, Carotid endarterectomy Clinical Sciences Source Type: research

Outcome determinants of stroke in a brazilian primary stroke center.
Conclusions. The stroke mortality and stroke outcome determinants found in the present study do not remarkably differ from studies carried out in developed countries. Stroke prognosis studies are crucial to better understand the high burden of stroke in Brazil. PMID: 25580352 [PubMed]
Source: Stroke Research and Treatment - January 13, 2015 Category: Neurology Tags: Stroke Res Treat Source Type: research

Can a Novel Clinical Risk Score Improve Pneumonia Prediction in Acute Stroke Care? A UK Multicenter Cohort Study Stroke
Conclusions The ISAN score is a simple tool for predicting SAP in clinical practice. External validation is required in ischemic and hemorrhagic stroke cohorts.
Source: JAHA:Journal of the American Heart Association - January 13, 2015 Category: Cardiology Authors: Smith, C. J., Bray, B. D., Hoffman, A., Meisel, A., Heuschmann, P. U., Wolfe, C. D. A., Tyrrell, P. J., Rudd, A. G., the Intercollegiate Stroke Working Party Group Tags: Stroke Source Type: research

Fibroblast Growth Factor 23 and Risk of Incident Stroke in Community-Living Adults Clinical Sciences
Conclusions— Higher FGF23 concentrations were associated with higher risk of cardioembolic but not with other stroke subtypes in community-dwelling adults. Additional studies should delineate reasons for these findings.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Panwar, B., Jenny, N. S., Howard, V. J., Wadley, V. G., Muntner, P., Kissela, B. M., Judd, S. E., Gutierrez, O. M. Tags: Acute Cerebral Infarction, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

Community-Based Case-Control Study of Childhood Stroke Risk Associated With Congenital Heart Disease Clinical Sciences
Conclusions— CHD is an important childhood stroke risk factor. Children who undergo CHD surgery remain at elevated risk outside the perioperative period and would benefit from optimized long-term stroke prevention strategies.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Fox, C. K., Sidney, S., Fullerton, H. J. Tags: Pediatric and congenital heart disease, including cardiovascular surgery, Risk Factors for Stroke, Stroke in Children and the Young, Epidemiology Clinical Sciences Source Type: research

Job Strain and the Risk of Stroke: An Individual-Participant Data Meta-Analysis Brief Reports
Conclusion— Job strain may be associated with an increased risk of ischemic stroke, but further research is needed to determine whether interventions targeting job strain would reduce stroke risk beyond existing preventive strategies.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Fransson, E. I., Nyberg, S. T., Heikkila, K., Alfredsson, L., Bjorner, J. B., Borritz, M., Burr, H., Dragano, N., Geuskens, G. A., Goldberg, M., Hamer, M., Hooftman, W. E., Houtman, I. L., Joensuu, M., Jokela, M., Knutsson, A., Koskenvuo, M., Koskinen, A. Tags: Behavioral/psychosocial - stroke, Epidemiology Brief Reports Source Type: research

Relevance of Blood-Brain Barrier Disruption After Endovascular Treatment of Ischemic Stroke: Dual-Energy Computed Tomographic Study Clinical Sciences
Conclusions— Blood–brain barrier disruption, defined as CS and BH on dual-energy CT, was associated with poor clinical outcomes in patients with stroke treated with endovascular therapies. Moreover, isolated CS was associated with delayed hemorrhagic transformation. These results support the clinical relevance of blood–brain barrier disruption in acute stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Renu, A., Amaro, S., Laredo, C., Roman, L. S., Llull, L., Lopez, A., Urra, X., Blasco, J., Oleaga, L., Chamorro, A. Tags: Cerebrovascular disease/stroke, Computerized tomography and Magnetic Resonance Imaging, Thrombolysis Clinical Sciences Source Type: research

Drip and Ship Thrombolytic Therapy for Acute Ischemic Stroke: Use, Temporal Trends, and Outcomes Clinical Sciences
Conclusions— Drip and ship tPA is common, used in 1 in 4 patients treated with tPA in the United States. Modest differences in mortality and symptomatic intracranial hemorrhage may be because of patient selection bias, post-tPA care differences, or unmeasured confounding. The drip and ship paradigm may facilitate widespread tPA use in patients with acute stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sheth, K. N., Smith, E. E., Grau-Sepulveda, M. V., Kleindorfer, D., Fonarow, G. C., Schwamm, L. H. Tags: Acute Cerebral Infarction, Acute Stroke Syndromes, Embolic stroke, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Improved Prehospital Triage of Patients With Stroke in a Specialized Stroke Ambulance: Results of the Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Study Clinical Sciences
Conclusions— The triage of patients with cerebrovascular events to specialized hospitals can be improved by STEMO ambulances. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT01382862.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Wendt, M., Ebinger, M., Kunz, A., Rozanski, M., Waldschmidt, C., Weber, J. E., Winter, B., Koch, P. M., Freitag, E., Reich, J., Schremmer, D., Audebert, H. J., for the STEMO Consortium Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Emergency treatment of Stroke, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Alteplase for Acute Ischemic Stroke: Outcomes by Clinically Important Subgroups in the Third International Stroke Trial Clinical Sciences
Conclusions— Among the types of patient in the Third International Stroke Trial, this secondary analysis did not identify any subgroups for whom treatment should be avoided. Given the limitations of the analysis, we found no clear evidence to avoid treatment in patients with prior ischemic stroke, diabetes mellitus, or hypertension. Clinical Trial Registration— URL: http://www.controlled-trials.com. Unique identifier: ISRCTN25765518. http://www.controlled-trials.com/ISRCTN25765518.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Lindley, R. I., Wardlaw, J. M., Whiteley, W. N., Cohen, G., Blackwell, L., Murray, G. D., Sandercock, P. A. G., on behalf of the IST-3 Collaborative Group, Trial Steering Committee, Baigent, Chadwick, Tyrrell, Lowe, Dennis, Innes, Goodare, CT and MR readi Tags: Acute Cerebral Infarction, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Adherence to a Mediterranean Diet and Prediction of Incident Stroke Clinical Sciences
Conclusions— High adherence to MeD seems to be associated with a lower risk of incident IS independent of potential confounders. Adherence to MeD is not related to the risk of incident hemorrhagic stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Tsivgoulis, G., Psaltopoulou, T., Wadley, V. G., Alexandrov, A. V., Howard, G., Unverzagt, F. W., Moy, C., Howard, V. J., Kissela, B., Judd, S. E. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Risk Factors for Stroke Clinical Sciences Source Type: research

Evaluation of a Telephone Advice System for Remote Intravenous Thrombolysis in Ischemic Stroke: Data From a United Kingdom Network Brief Reports
Conclusion— Telephone advice and teleradiology, within an organized system of care, can be an effective method of delivery of intravenous thrombolysis.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Dutta, D., Kendall, J., Holmes, C., Murphy, P., Black, T., Whiting, R., Aujla, K., Caine, S., Hellier, K., Walters, D. Tags: Emergency treatment of Stroke, Thrombolysis Brief Reports Source Type: research

Effects of Blood Pressure-Lowering Treatment in Different Subtypes of Acute Ischemic Stroke Brief Reports
Conclusions— The results suggest that the effect of blood pressure–lowering treatment with candesartan may differ according to different types of acute ischemic stroke, but this needs to be confirmed in future trials. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sandset, E. C., Jusufovic, M., Sandset, P. M., Bath, P. M. W., Berge, E., on behalf of the SCAST Study Group Tags: Cerebrovascular disease/stroke, Clinical Studies Brief Reports Source Type: research

Effect of Seasonal and Monthly Variation in Weather and Air Pollution Factors on Stroke Incidence in Seoul, Korea Clinical Sciences
Conclusions— We demonstrated distinct patterns of seasonal and monthly variation in the incidence of stroke and its subtypes through consideration of the meteorologic and air pollution parameters. We therefore expect that these findings may enhance our understanding of the relationships between stroke and weather and pollutants.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Han, M.-H., Yi, H.-J., Kim, Y.-S., Kim, Y.-S. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Risk Factors for Stroke Clinical Sciences Source Type: research

How Is Pneumonia Diagnosed in Clinical Stroke Research?: A Systematic Review and Meta-Analysis Clinical Sciences
Conclusions— We found considerable variation in terminology and the diagnostic approach to pneumonia. Our review supports the need for consensus development of operational diagnostic criteria for pneumonia complicating stroke.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Kishore, A. K., Vail, A., Chamorro, A., Garau, J., Hopkins, S. J., Di Napoli, M., Kalra, L., Langhorne, P., Montaner, J., Roffe, C., Rudd, A. G., Tyrrell, P. J., van de Beek, D., Woodhead, M., Meisel, A., Smith, C. J. Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Acute Stroke Syndromes, Other Stroke Treatment - Medical Clinical Sciences Source Type: research

The pooled incidence of post-stroke seizure in 102 008 patients.
CONCLUSIONS: Our meta-analysis showed that seizures occurred in about 6.93% of people with stroke. Seizures occurred more commonly after hemorrhagic stroke and when stroke occurred in the cortical region. PMID: 25920619 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - April 28, 2015 Category: Neurology Authors: Zou S, Wu X, Zhu B, Yu J, Yang B, Shi J Tags: Top Stroke Rehabil Source Type: research

Acute Reperfusion Therapy and Stroke Care in Asia After Successful Endovascular Trials Understanding and Applying the Endovascular Trials
The current status of and prospects for acute stroke care in Asia in the situation where both intravenous thrombolysis and endovascular therapies have been recognized as established strategies for acute stroke are reviewed. Of 15 million people annually having stroke worldwide, 9 million are Asians. The burdens of both ischemic and hemorrhagic strokes are severe in Asia. The unique features of stroke in Asia include susceptibility to intracranial atherosclerosis, high prevalence of intracerebral hemorrhage, effects of dietary and lifestyle habits, and several disorders with genetic causes. These features affect acute strok...
Source: Stroke - May 22, 2015 Category: Neurology Authors: Toyoda, K., Koga, M., Hayakawa, M., Yamagami, H. Tags: Emergency treatment of Stroke, Anticoagulants, Thrombolysis, Angioplasty and Stenting Understanding and Applying the Endovascular Trials Source Type: research

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline
Conclusions— Intracerebral hemorrhage remains a serious condition for which early aggressive care is warranted. These guidelines provide a framework for goal-directed treatment of the patient with intracerebral hemorrhage.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Hemphill, J. C., Greenberg, S. M., Anderson, C. S., Becker, K., Bendok, B. R., Cushman, M., Fung, G. L., Goldstein, J. N., Macdonald, R. L., Mitchell, P. H., Scott, P. A., Selim, M. H., Woo, D., on behalf of the American Heart Association Stroke Council, Tags: AHA Statements and Guidelines AHA/ASA Guideline Source Type: research

Predictors for total medical costs for acute hemorrhagic stroke patients transferred to the rehabilitation ward at a regional hospital in Taiwan.
CONCLUSIONS: Our findings could help clinicians to understand that cost reduction may be achieved by minimizing complications (pneumonia and UTI) in these patients. PMID: 26094779 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - June 20, 2015 Category: Neurology Authors: Chen CM, Ke YL Tags: Top Stroke Rehabil Source Type: research