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Predictors of Recurrent Ischemic Stroke in Obese Patients With Type 2 Diabetes Mellitus: A Population-based Study
Each year, approximately 0.8 million people are estimated to experience a new or recurrent stroke, according to the 2019 report of the American Heart Association.1 In Malaysia, stroke is the third leading cause of death after ischemic heart disease (IHD) and pneumonia.2 Both obesity and diabetes are considered as the established independent risk factors for ischemic stroke.3 Type 2 diabetes mellitus (T2DM) was also found to be associated with an increase in all-cause as well as cardiovascular mortality following the stroke,4,5 and in a meta-analysis of 18 studies, patients with diabetes had a higher stroke recurrence as co...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Orwa Albitar, Sabariah Noor Harun, Nur Ezzati Abidin, Balamurugan Tangiisuran, Hadzliana Zainal, Irene Looi, Khairul Azmi Ibrahim, Norsima Nazifah Sidek, Keat Wei Loo, Keng Yee Lee, Zariah Abdul Aziz, Siti Maisharah Sheikh Ghadzi Source Type: research

Association between recent cannabinoid use and acute ischemic stroke
Conclusion This is one of the few studies analyzing the association of recent cannabis use and AIS using admission urine toxicology test independent of polysubstance use. Although our study has limitations, we did not find an independent association between recent cannabis use and the incidence of AIS. Further studies using urine toxicology tests with larger sample size and including dosage of cannabis exposure should be conducted.
Source: Neurology Clinical Practice - August 9, 2020 Category: Neurology Authors: San Luis, C. V., O'Hana S. Nobleza, C., Shekhar, S., Sugg, R., Villareal, D. J., Mehta, T., Gangadhara, S. Tags: All Cerebrovascular disease/Stroke, Other toxicology Research Source Type: research

Obesity Drives Delayed Infarct Expansion, Inflammation, and Distinct Gene Networks in a Mouse Stroke Model
AbstractObesity is associated with chronic peripheral inflammation, is a risk factor for stroke, and causes increased infarct sizes. To characterize how obesity increases infarct size, we fed a high-fat diet to wild-type C57BL/6J mice for either 6  weeks or 15 weeks and then induced distal middle cerebral artery strokes. We found that infarct expansion happened late after stroke. There were no differences in cortical neuroinflammation (astrogliosis, microgliosis, or pro-inflammatory cytokines) either prior to or 10 h after stroke, and also no differences in stroke size at 10 h. However, by 3 days after stroke, animals...
Source: Translational Stroke Research - June 24, 2020 Category: Neurology Source Type: research

Stroke Induces Prolonged Changes in Lipid Metabolism, the Liver and Body Composition in Mice
AbstractDuring recovery, stroke patients are at risk of developing long-term complications that impact quality of life, including changes in body weight and composition, depression and anxiety, as well as an increased risk of subsequent vascular events. The aetiologies and time-course of these post-stroke complications have not been extensively studied and are poorly understood. Therefore, we assessed long-term changes in body composition, metabolic markers and behaviour after middle cerebral artery occlusion in mice. These outcomes were also studied in the context of obesity, a common stroke co-morbidity proposed to prote...
Source: Translational Stroke Research - December 20, 2019 Category: Neurology Source Type: research

Obesity Paradox in Ischemic Stroke: Clinical and Molecular Insights
AbstractIt has recently emerged the concept of “obesity paradox,” a term used to describe the unexpected improved prognosis and lower mortality rates found in several diseases in patients with higher body weight. Concerning stroke, few clinical studies have assessed this obesity paradox showing contradictory results. Therefore, our aim was t o compare clinical evolution and inflammatory balance of obese and non-obese patients after ischemic stroke. We designed a prospective case-control study in patients with acute ischemic stroke categorized into obese (body mass index, BMI ≥ 30 kg/m2) and non-obese (BMI  <...
Source: Translational Stroke Research - April 12, 2019 Category: Neurology Source Type: research

Diet Drinks Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Diet Beverages Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Self-Reported Body Weight Changes, Perceptions, and Weight Loss Techniques among Stroke Survivors
Background: Little is known about the body weight goals and trends of stroke survivors, despite evidence that overweight and obesity can negatively influence poststroke rehabilitation outcomes. Thus, the purpose of this study was to identify self-reported body weight trends over time in stroke survivors and nonstroke controls (>50 years old) and describe the methods used to attempt to achieve body weight goals. Methods: Self-reported body weight 1) at age 25 years, 2) 10 years prior to the current assessment, 3) 1 year prior to the current assessment, 4) current weight, and 5) age of heaviest body weight were collected fro...
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2019 Category: Neurology Authors: Jessica L. Kelleher, Paul Weiss, Amy D. Rodriguez, Joe R. Nocera, Monica C. Serra Source Type: research

Television Viewing Time and Stroke Risk: Australian Diabetes Obesity and Lifestyle Study (1999-2012)
Introduction: Having a low level of physical activity is an established risk factor for stroke, but little is known about the importance of common sedentary behavior —television viewing—to stroke risk. Methods: We conducted a retrospective analysis of data that were collected as part of the longitudinal Australian Diabetes, Obesity, and Lifestyle study. Stroke events reported during the study (between baseline assessment in 1999-2000 and April 2011) were con firmed using adjudication based on medical records.
Source: Journal of Stroke and Cerebrovascular Diseases - January 22, 2019 Category: Neurology Authors: Toby B. Cumming, Elizabeth Holliday, David Dunstan, Coralie English Source Type: research

Moderate-to-vigorous physical activity and the risk of stroke recurrence in patients with a history of minor ischemic stroke in Japan: a retrospective analysis.
CONCLUSIONS: Patients with a history of mild ischemic stroke had low MVPA and high VFL values, which together may be a risk factor for RIS. PMID: 30207894 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 12, 2018 Category: Neurology Authors: Ushio M, Kanaoka M, Kinoshita Y, Maeno S, Fujita K Tags: Top Stroke Rehabil Source Type: research

High-Resolution Pulse Oximetry (HRPO): A Cost-Effective Tool in Screening for Obstructive Sleep Apnea (OSA) in Acute Stroke and Predicting Outcome
Obstructive sleep apnea (OSA) is a well-known risk factor for stroke. This is attributed to multiple mechanisms such as endothelial dysfunction, atrial fibrillation, hypertension, and comorbid obesity. STOP questionnaire alone is unreliable to diagnose OSA and in-hospital sleep study is costly and can be technically challenging. We used high-resolution pulse oximetry (HRPO) to test the feasibility of screening for OSA and predicting outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - August 7, 2018 Category: Neurology Authors: Sridhara Sastry Yaddanapudi, Maria Carissa Pineda, David W. Boorman, Richard E. Bryne, Krista Lim Hing, Sunil Sharma Source Type: research

Adductor Pollicis Muscle Thickness and Obesity Are Associated with Poor Outcome after Stroke: A Cohort Study
Nutritional status may influence outcome after stroke. It is possible that some obese individuals present reduced fat-free mass.
Source: Journal of Stroke and Cerebrovascular Diseases - February 1, 2018 Category: Neurology Authors: Juli Thomaz de Souza, Marcos Ferreira Minicucci, Leonardo Ant ônio Mamede Zornoff, Bertha Furlan Polegato, Priscila Watson Ribeiro, Silméia Garcia Zanati Bazan, Gabriel Pereira Braga, Gustavo José Luvizutto, Sérgio Alberto Rupp de Paiva, Rodrigo Bazan Source Type: research

Rapid transitions in the epidemiology of stroke and its risk factors in China from 2002 to 2013
Conclusions: In 2002–2013, the incidence of stroke in China increased rapidly. Combined with a high prevalence, a trend toward a younger age, and stable mortality, this finding suggests that additional clinical and behavioral interventions for metabolic and lifestyle risk factors are necessary to prevent stroke, particularly in certain populations.
Source: Neurology - July 3, 2017 Category: Neurology Authors: Guan, T., Ma, J., Li, M., Xue, T., Lan, Z., Guo, J., Shen, Y., Chao, B., Tian, G., Zhang, Q., Wang, L., Liu, Y. Tags: All Cerebrovascular disease/Stroke, Prevalence studies, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults Clinical Sciences
Conclusions—Modifiable risk factors previously established in older populations also account for a large part of stroke in younger adults, with 4 risk factors explaining almost 80% of stroke risk.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Annette Aigner, Ulrike Grittner, Arndt Rolfs, Bo Norrving, Bob Siegerink, Markus A. Busch Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Burden and Predictors of Poststroke Cognitive Impairment in a Sample of Ghanaian Stroke Survivors
There are limited data on vascular cognitive impairment (VCI) from low- and middle-income countries where the stroke burden is burgeoning. The aim of this study was to characterize the burden, determinants, and effects of VCI on health-related quality of life in sub-Saharan Africa (SSA).
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2017 Category: Neurology Authors: Fred Stephen Sarfo, John Akassi, Sheila Adamu, Vida Obese, Bruce Ovbiagele Source Type: research

Physical activity, but not body mass index, predicts less disability before and after stroke
Conclusions: Physical inactivity predicts a higher risk of being dependent both before and after stroke.
Source: Neurology - May 1, 2017 Category: Neurology Authors: Rist, P. M., Capistrant, B. D., Mayeda, E. R., Liu, S. Y., Glymour, M. M. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Impact of Tissue Plasminogen Activator Dosing on Patients Weighing More Than 100  kg on 3-Month Outcomes in Acute Ischemic Stroke
The landmark National Institute of Neurological Disorders and Stroke (NINDS) tissue plasminogen activator (tPA) trial established the effectiveness and dosing of intravenous tPA for acute ischemic stroke (AIS) at .9  mg/kg with a maximum dose of 90 mg. Since the publication of the NINDS trial in 1995, there has been a drastic increase in the amount of obesity and the average weight of adults in the United States, which has caused an increase in the number of patients receiving 90 mg of alteplase for AIS.
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2017 Category: Neurology Authors: Jeffrey Garavaglia, Jay Sherman, Hannah Yetzer, Michael Regier, Matthew Smith Source Type: research

Lacunar Infarcts and Intracerebral Hemorrhage Differences Brief Report
Background and Purpose—Lacunar stroke (LS) and intracerebral hemorrhage (ICH) are 2 diverse manifestations of small vessel disease. What predisposes some patients to ischemic stroke and others to hemorrhage is not well understood.Methods—We performed a nested case–control study within the FHS (Framingham Heart Study) comparing people with incident ICH and lacunar ischemic stroke, to age- and sex-matched controls for baseline prevalence and levels of cardiovascular risk factors.Results—We identified 118 LS (mean age 74 years, 51% male) and 108 ICH (75 years, 46% male) events. Hypertension, diabetes mellitus, smoking...
Source: Stroke - January 22, 2017 Category: Neurology Authors: Vasileios-Arsenios Lioutas, Alexa Beiser, Jayandra Himali, Hugo Aparicio, Jose Rafael Romero, Charles DeCarli, Sudha Seshadri Tags: Obesity, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Brief Reports Source Type: research

Body mass index and stroke in UK women: "Obesity paradox" revisited
Obesity is a major risk factor for stroke. However, several studies have reported a protective effect of obesity on stroke, particularly after a prior cardiovascular event, a phenomenon described as the "obesity paradox" or "reverse epidemiology."1 No convincing biological evidence explains this paradox. The evidence that increased body mass index (BMI) increases risk for ischemic stroke in Western and Asian populations is strong, but the relationship with hemorrhagic stroke remains less established.
Source: Neurology - October 2, 2016 Category: Neurology Authors: Rexrode, K., Rundek, T. Tags: All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology, Intracerebral hemorrhage, Subarachnoid hemorrhage EDITORIALS Source Type: research

Medical News Today: Obesity does not predict equal risk for all stroke types
Being overweight or obese is a well-known risk factor for stroke. However, recent research shows that this risk is not equal across all types of stroke.
Source: Health News from Medical News Today - September 8, 2016 Category: Consumer Health News Tags: Stroke Source Type: news

Overweight and Obesity in Young Adulthood and the Risk of Stroke: a Meta-analysis
A systematic review assessing the association between overweight and obesity in young adulthood and stroke risk is lacking. Therefore, we conducted a meta-analysis to evaluate the association between overweight and obesity in young adulthood and stroke risk.
Source: Journal of Stroke and Cerebrovascular Diseases - September 7, 2016 Category: Neurology Authors: Yan Guo, Xue-jing Yue, He-hua Li, Zhi-xiu Song, Hai-qing Yan, Ping Zhang, Yong-kun Gui, Li Chang, Tong Li Source Type: research

Determinants in Adolescence of Stroke-Related Hospital Stay Duration in Men: A National Cohort Study Brief Reports
Conclusions— Some characteristics relevant to length of stroke-related hospital stay and risk of second stroke are already present in adolescence. Early lifestyle influences are of importance not only to stroke risk by middle age but also to recurrence and use of healthcare resources among stroke survivors.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Bergh, C., Udumyan, R., Appelros, P., Fall, K., Montgomery, S. Tags: Epidemiology, Lifestyle, Risk Factors, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Brunei epidemiological stroke study: patterns of hypertension and stroke risk
Conclusion: The prevalence of hypertension in Brunei is high in both women and men. Information campaigns and prevention programs are needed to be able to cope with the increasing problem of hypertension and resulting diseases like stroke in Brunei in the near future.
Source: Journal of Hypertension - June 4, 2016 Category: Cardiology Tags: ORIGINAL PAPERS: Stroke Source Type: research

Women Had Worse Stroke Outcome (P1.217)
Conclusion: in our cohort women have worst post-stroke outcome, even though they have higher burden of vascular risk factors they have lower prevalence of vascular disease in other vascular beds previous to stroke. This difference persists after adjusting by age, raising the possibility of specific gender risk factors influencing on ischemic stroke outcomes.Disclosure: Dr. Zurru has nothing to disclose. Dr. Colla Machado has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Luzzi has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Balian has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zurru, M., Colla Machado, P., Alonzo, C., Brescacin, L., Luzzi, A., Pigretti, S., Balian, N., Waisman, G., Cristiano, E. Tags: Re-admission and Stroke Outcomes Source Type: research

Trends in Age of First-Ever Stroke Following Increased Incidence and Life Expectancy in a Low-Income Chinese Population Clinical Sciences
Conclusions— The age of stroke onset tends to be younger among low-income population in China after the dramatic increased incidence of stroke during the gradual extension of life expectancy of population in China. These findings suggested that stroke burden will continue to increase in the long time, unless the risk factors in low-income populations are effectively controlled.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Wang, J., Bai, L., Shi, M., Yang, L., An, Z., Li, B., Zhao, W., Gu, H., Zhan, C., Tu, J., Ning, X. Tags: Epidemiology, Lifestyle, Primary Prevention, Risk Factors, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Obesity and Abdominal Fat Markers in Patients with a History of Stroke and Transient Ischemic Attacks
The objective of this study was to analyze the association between anthropometric parameters and the risk of stroke and transient ischemic attacks (TIAs) in German primary care.
Source: Journal of Stroke and Cerebrovascular Diseases - February 22, 2016 Category: Neurology Authors: Yaroslav Winter, Lars Pieper, Jens Klotsche, Oliver Riedel, Hans-Ulrich Wittchen Source Type: research

Fitness and cognition in the elderly: The Austrian Stroke Prevention Study
Conclusions: Higher Vo2max is associated with better global cognitive function and with better performance in the cognitive domains of memory, executive function, and motor skills in the middle-aged and elderly. The association is not mediated by the presence of white matter lesions, lacunes, and brain atrophy.
Source: Neurology - February 1, 2016 Category: Neurology Authors: Freudenberger, P., Petrovic, K., Sen, A., Toglhofer, A. M., Fixa, A., Hofer, E., Perl, S., Zweiker, R., Seshadri, S., Schmidt, R., Schmidt, H. Tags: MRI, All Cerebrovascular disease/Stroke, Cognitive aging, Cohort studies ARTICLE Source Type: research

Multilingual Validation of the Questionnaire for Verifying Stroke-Free Status in West Africa Clinical Sciences
Conclusions— QVSFS is a valid tool for verifying stroke-free status across culturally diverse populations in West Africa.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Sarfo, F., Gebregziabher, M., Ovbiagele, B., Akinyemi, R., Owolabi, L., Obiako, R., Akpa, O., Armstrong, K., Akpalu, A., Adamu, S., Obese, V., Boa-Antwi, N., Appiah, L., Arulogun, O., Mensah, Y., Adeoye, A., Tosin, A., Adeleye, O., Tabi-Ajayi, E., Phillip Tags: Diagnostic Testing Clinical Sciences Source Type: research

Obese Japanese Patients with Stroke Have Higher Functional Recovery in Convalescent Rehabilitation Wards: A Retrospective Cohort Study
This study aimed to explore whether obese patients with stroke have advantages for functional improvement in Japanese rehabilitation wards.
Source: Journal of Stroke and Cerebrovascular Diseases - September 21, 2015 Category: Neurology Authors: Shinta Nishioka, Hidetaka Wakabayashi, Tomomi Yoshida, Natsumi Mori, Riko Watanabe, Emi Nishioka Source Type: research

Sex Differences in Outcomes and Associated Risk Factors After Acute Ischemic Stroke in Elderly Patients: A Prospective Follow-up Study
Stroke has a greater effect on women. However, sex differences in outcome and factors associated with outcome among elderly patients are unknown. From January 2009 to December 2011, 810 patients with acute ischemic stroke aged 75 years or older were recruited in China. Clinical profile and risk factors were recorded. Outcomes and associated risk factors at 12 and 36 months after stroke were assessed by sex. Hypertension, diabetes mellitus, dyslipidemias, and obesity prevalence rates were higher in women than in men; opposite trends were found for smoking and alcohol consumption.
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2015 Category: Neurology Authors: Bin Li, Tao Wang, Yongzhong Lou, Xiaofei Guo, Hongfei Gu, Yanxia Zhu, Xianjia Ning, Jinghua Wang, Jun Tu Source Type: research

Obesity-stroke paradox and initial neurological severity
Conclusions In our study, although obesity was associated with better short-term functional outcomes, INS might be a more important prognostic factor. Therefore, initial status should also be considered when considering an ‘obesity paradox’ in chronic diseases.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 12, 2015 Category: Neurosurgery Authors: Kim, Y., Kim, C. K., Jung, S., Yoon, B.-W., Lee, S.-H. Tags: Stroke Cerebrovascular disease Source Type: research

Obesity Increases Risk of Ischemic Stroke in Young Adults Brief Reports
Conclusions— These results indicate that obesity is a risk factor for young onset ischemic stroke and suggest that this association may be partially mediated through hypertension, diabetes mellitus, or other variables associated with these conditions.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Mitchell, A. B., Cole, J. W., McArdle, P. F., Cheng, Y.-C., Ryan, K. A., Sparks, M. J., Mitchell, B. D., Kittner, S. J. Tags: Risk Factors for Stroke Brief Reports Source Type: research

Abstract 206: Aiming to Improve Stroke Care Continuity with Primary Care Follow-up Appointments Scheduled Prior to Hospital Discharge Session Title: Poster Session II
Conclusions: Hospital performance with scheduling primary care follow-up appointments improved significantly; however, only 1 in 4 patients had an appointment scheduled prior to discharge. Case study analysis of missed opportunities may help identify barriers and facilitators associated with access, availability, and awareness that can be addressed in future improvement cycles.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Prvu Bettger, J., Burns, B., Lender, S., Nutter, D., On Behalf of the Ohio Coverdell Stroke Program Leadership, Participating Hosps and Partners Tags: Session Title: Poster Session II Source Type: research

The Obesity Paradox and Survivors of Ischemic Stroke
Although obesity is a risk factor for stroke and achieving normal weight is advocated to decrease stroke risk, the risk associated with obesity and weight loss after stroke has not been well established. The aim of this study was to assess the association of obesity at the time of stroke admission and weight loss after stroke with total mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2015 Category: Neurology Authors: Peter Wohlfahrt, Francisco Lopez-Jimenez, Alena Krajcoviechova, Marie Jozifova, Otto Mayer, Jiri Vanek, Jan Filipovsky, Ernesto M. Llano, Renata Cifkova Source Type: research

Predictors Of Early Mortality And Bad Outcome In Ischemic Stroke (P3.072)
Conclusion: identifying predictors of early mortality or post-stroke disability is mandatory in order to recognize opportunities of improvement and develop strategies for clinical care in this specific subgroup of patients. A multidisciplinary approach is essential to reduce clinical complications and to improve follow up after the hospitalization period.Disclosure: Dr. Luzzi has nothing to disclose. Dr. Zurru has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Camera has nothing to disclose. Dr. Colla Machado has nothing to disclose....
Source: Neurology - April 8, 2015 Category: Neurology Authors: Luzzi, A., Zurru, M., Alonzo, C., Brescacin, L., Pigretti, S., Camera, L., Colla Machado, P., Waisman, G., Cristiano, E. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Risk of ischemic stroke during periods of warfarin discontinuation for surgical procedures: A longitudinal study of 4060 patients with atrial fibrillation (P1.058)
CONCLUSIONS: The risk associated with discontinuation of warfarin for procedures must be recognized and considered in the risk benefit analysis of any procedure.Disclosure: Dr. Jahangir has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Suri has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jahangir, N., Malik, A., Suri, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Atrial Fibrillation and Cardio-embolic Stroke Source Type: research

Body Mass Index and Stroke Subtype in a Young Adult Stroke Population (P7.126)
CONCLUSIONS: In our group of young adult stroke patients, we found the highest BMI in the group with intracranial atherosclerosis. Although this group represented a small number of patients, this young adult population is at increased risk for future strokes. It is important to educate them on lifestyle modifications such as weight loss and exercise in addition to the treatment of hypertension, diabetes mellitus and hyperlipidemia.Disclosure: Dr. Youn has nothing to disclose. Dr. Aung has nothing to disclose. Dr. Afrasiabi has nothing to disclose. Dr. Clark has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Youn, J., Aung, T., Afrasiabi, M., Clark, J. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke in Young Source Type: research

Comparison of major modifiable stroke risk factors associated with lacunar strokes in anterior and posterior circulation in multiethnic cohort (P7.143)
CONCLUSIONS: Hypertriglyceridemia may be associated with posterior circulation SVD. In the setting of the obesity epidemic, hypertriglyceridemia prevalence is increasing; therefore, we might expect a concomitant increase in the incidence of posterior circulation strokes.Disclosure: Dr. Bulic has nothing to disclose. Dr. Valle has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Bulic, S., Valle, N., Towfighi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Are there Different Rates of Acute Stroke Risk Factors in the South Texas Mexican American population? (P7.146)
CONCLUSION: In the South Texas Mexican American AIS population, there is greater then a three-fold higher prevalence of hypertension, diabetes and CHF compared with Hispanics/Latinos in the US. AFIB and CHF are significant predictors of poor outcome in this unique population.Disclosure: Dr. Tekle has nothing to disclose. Dr. Hassan has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Jones-Fullingim has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Abantao has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tekle, W., Hassan, A., Malik, A., Jones-Fullingim, L., Sanchez, C., Jani, V., Sanchez, O., Abantao, E., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

The Obesity Paradox in Stroke: Impact on Mortality and Short-term Readmission
The aim of the present study was to assess the association of obesity with the mortality of hospitalized patients with acute stroke and the risk of readmission in less than 30 days.
Source: Journal of Stroke and Cerebrovascular Diseases - February 7, 2015 Category: Neurology Authors: Raquel Barba, Javier Marco, Justo Ruiz, Jesús Canora, Juan Hinojosa, Susana Plaza, Antonio Zapatero Source Type: research

Increasing stroke incidence and prevalence of risk factors in a low-income Chinese population
Conclusions: The incidence of stroke in rural China increased rapidly, particularly among middle-aged adults, along with a concurrent increase in risk factor prevalence. These findings suggest that without controlling these risk factors, stroke incidence will continue to increase over future decades in China.
Source: Neurology - January 26, 2015 Category: Neurology Authors: Wang, J., An, Z., Li, B., Yang, L., Tu, J., Gu, H., Zhan, C., Liu, B., Su, T.-C., Ning, X. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Body Mass Index and Stroke Risk Among Patients With Type 2 Diabetes Mellitus Clinical Sciences
Conclusions— The present study demonstrates an inverse association between BMI and stroke risk among patients with type 2 diabetes mellitus.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Li, W., Katzmarzyk, P. T., Horswell, R., Zhang, Y., Zhao, W., Wang, Y., Johnson, J., Hu, G. Tags: Obesity, Type 2 diabetes, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Stroke in Asia: a global disaster
Although stroke is a world‐wide problem, the burden of stroke is particularly serious in Asia; its mortality is higher than in Europe or North America. The situation in Asia is dichotomized. Stroke mortality and case fatality has been declining in northern‐eastern countries such as Korea, Japan, Taiwan, and urbanized areas of China. This is attributed to both the risk factor control and stroke care improvement. However, declining stroke incidence is rarely observed, which is in part due to rapidly aging population. As a result, there is an increase in the number of stroke survivors who require long‐term, costly care....
Source: International Journal of Stroke - September 18, 2014 Category: Neurology Authors: Jong S. Kim Tags: Leading opinion Source Type: research

Adult stroke risk after growth hormone treatment in childhood: First do no harm
This report has been much anticipated by the endocrinology community because it extends and clarifies findings in a 2012 study showing increased mortality in adults treated in childhood with GH from the prospective European cohort study—the Safety and Appropriateness of Growth Hormone Treatments in Europe (SAGhE).3
Source: Neurology - August 25, 2014 Category: Neurology Authors: Ichord, R. N. Tags: Stroke in young adults, All Cerebrovascular disease/Stroke, Patient safety, Cohort studies EDITORIALS Source Type: research

Neighborhood socioeconomic status and the prevalence of stroke and coronary heart disease in rural China: A population‐based study
ConclusionsThere were differences in vascular risk across rural villages in China, with higher lifetime stroke and CHD prevalence in higher‐income villages. For CHD, neighborhood effects were stronger among younger residents of high‐income villages. The results may have implications for public health interventions targeting populations at risk.
Source: International Journal of Stroke - August 4, 2014 Category: Neurology Authors: Xun Tang, Daniel T. Laskowitz, Liu He, Truls Østbye, Janet Prvu Bettger, Yang Cao, Na Li, Jingrong Li, Zongxin Zhang, Jianjiang Liu, Liping Yu, Haitao Xu, Yonghua Hu, Larry B. Goldstein Tags: Research Source Type: research

Socioeconomic Position and Incidence of Ischemic Stroke in Denmark 2003-2012. A Nationwide Hospital-Based Study Stroke
Conclusions In Denmark, there is a strong relation between low socioeconomic position and risk for hospitalization for stroke. Lifestyle, as indicated by smoking, obesity, and alcohol consumption, and diabetes appears to increase the risk for stroke in people with lower socioeconomic position.
Source: JAHA:Journal of the American Heart Association - July 16, 2014 Category: Cardiology Authors: Andersen, K. K., Steding-Jessen, M., Dalton, S. O., Olsen, T. S. Tags: Stroke Source Type: research

Primary Preventive Potential for Stroke by Avoidance of Major Lifestyle Risk Factors: The European Prospective Investigation Into Cancer and Nutrition-Heidelberg Cohort Clinical Sciences
Conclusions— Our analysis confirms the strong primary prevention potential for stroke based on avoidance of excess body weight, smoking, heavy alcohol consumption, unhealthy diet, and physical inactivity.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Tikk, K., Sookthai, D., Monni, S., Gross, M.-L., Lichy, C., Kloss, M., Kaaks, R. Tags: Primary and Secondary Stroke Prevention, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Sex Differences in Trends of Incidence and Mortality of First-Ever Stroke in Rural Tianjin, China, From 1992 to 2012 Clinical Sciences
Conclusions— There was a significant increase in the incidence of first-ever stroke in women annually and a declining trend in the male/female rate ratio in rural China during the past 21 years. These results suggest that stroke will become one of the major diseases affecting women in future decades in China.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Wang, J., Ning, X., Yang, L., Tu, J., Gu, H., Zhan, C., Zhang, W., Su, T.-C. Tags: Epidemiology Clinical Sciences Source Type: research

The real stroke burden in the Philippines
Stroke is the Philippines' second leading cause of death. It has a prevalence of 0·9%; ischemic stroke comprises 70% while hemorrhagic stroke comprises 30%. Age‐adjusted hypertension prevalence is 20·6%, diabetes 6·0%, dyslipidemia 72·0%, smoking 31%, and obesity 4·9%. The neurologist‐to‐patient ratio is 1:330·000, with 67% of neurologists practicing in urban centers. Health care is largely private and the cost is borne out‐of‐pocket by patients and their families. Challenges include delivering adequate support to the rural communities and to the underprivileged sectors.
Source: International Journal of Stroke - May 20, 2014 Category: Neurology Authors: Jose C. Navarro, Alejandro C. Baroque, Johnny K. Lokin, Narayanaswamy Venketasubramanian Tags: Panorama Source Type: research