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Condition: Intermittent Claudication

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Total 74 results found since Jan 2013.

Surgical excision of a free floating ascending aortic thrombus
ConclusionFree ‐floating ascending aortic thrombus is a rare source of peripheral embolization. We advocate for emergent surgical resection to prevent further embolization and stroke.
Source: Journal of Cardiac Surgery - December 12, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Alex R. Dalal, Armita Kabirpour, John W. MacArthur Tags: IMAGES IN CARDIAC SURGERY Source Type: research

Left Subclavian Artery Revascularization for Thoracic Aortic Stentgrafting: Single Center Experience in 101 Patients
Introduction - Endovascular treatment of thoracic aortic pathology (TEVAR) requires a landing zone of at least 20mm in length, necessitating coverage of the left subclavian artery (LSA) in approximately 40% of the patients.1 Coverage of the LSA may increase the risk of ischaemic stroke, spinal cord ischaemia (SCI) and/or left arm claudication. Besides some endovascular options to preserve LSA flow, in the majority of cases the LSA is surgically revascularized by either a carotid-to-subclavian bypass graft or subclavian-carotid transposition.
Source: European Journal of Vascular and Endovascular Surgery - December 1, 2019 Category: Surgery Authors: Emma Van Der Weijde, Nabil Saouti, Olaf J. Bakker, Robin H. Heijmen Source Type: research

Metabolic-vascular coupling in skeletal muscle: a potential role for capillary pericytes?
Abstract The matching of capillary blood flow to metabolic rate of the cells within organs and tissues is a critical microvascular function which ensures appropriate delivery of hormones and nutrients, and the removal of waste products. This relationship is particularly important in tissues where local metabolism, and hence capillary blood flow, must be regulated to avoid a mismatch between nutrient demand and supply that would compromise normal function. The consequences of a mismatch in microvascular blood flow and metabolism are acutely apparent in the brain and heart, where a sudden cessation of blood flow, fo...
Source: Clinical and Experimental Pharmacology and Physiology - November 7, 2019 Category: Drugs & Pharmacology Authors: Attrill E, Ramsay C, Ross R, Richards S, Sutherland BA, Keske MA, Eringa E, Premilovac D Tags: Clin Exp Pharmacol Physiol Source Type: research

Characteristics of arterial hypertension in menopausal diabetic women
ConclusionHigh blood pressure is a public health problem most often associated with other cardiovascular risk factors. An evaluation of cardiovascular risk is necessary in postmenopausal hypertensive diabetic women and effective management of risk factors is recommended.
Source: Archives of Cardiovascular Diseases Supplements - July 24, 2019 Category: Cardiology Source Type: research

Arterial hypertension and diabetes association in the elderly
ConclusionVascular metabolic complications are serious in hypertensive elderly diabetic subjects; thus, multidisciplinary care and regular monitoring is required to detect these complications early and improve life expectancy.
Source: Archives of Cardiovascular Diseases Supplements - July 24, 2019 Category: Cardiology Source Type: research

Clinical Course, Management, and Outcomes of Pediatric Takayasu Arteritis Initially Presenting with Hypertension: a 16-year overview.
CONCLUSIONS: Majority of c-TA has hypertension, presenting with a more quiescent disease without typical systemic and/or ischemia symptoms, more localized abdominal lesions, higher proportion of revascularizations and better event-free survival. Three-year BP control is over 50%. Intervention particularly on renal artery is beneficial for BP control and decreased events. PMID: 31278892 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - July 5, 2019 Category: Cardiology Authors: Fan L, Zhang H, Cai J, Yang L, Wei D, Yu J, Fan J, Song L, Ma W, Lou Y Tags: Am J Hypertens Source Type: research

Steroid refractory giant cell arteritis with bilateral vertebral artery occlusion and middle cerebellar peduncle infarction.
We describe a 72-year-old male who developed bilateral vertebral artery occlusion and middle cerebellar peduncle infarction secondary to giant cell arteritis in spite of high-dose steroids. PMID: 31188339 [PubMed - in process]
Source: Journal of the Royal College of Physicians of Edinburgh - June 13, 2019 Category: General Medicine Tags: J R Coll Physicians Edinb Source Type: research

Asymptomatic Carotid Stenosis Is Associated With Circadian and Other Variability in Embolus Detection
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this t...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

A systematic review and meta-analysis of the effects of supervised exercise therapy on modifiable cardiovascular risk factors in intermittent claudication
The objective of this study was to determine the effects of supervised exercise therapy (SET) on modifiable cardiovascular risk factors in IC patients.
Source: Journal of Vascular Surgery - February 15, 2019 Category: Surgery Authors: Sandra C.P. Jansen, Beatrijs B.N. Hoorweg, Sanne E. Hoeks, Marijn M.L. van den Houten, Marc R.M. Scheltinga, Joep A.W. Teijink, Ellen V. Rouwet Source Type: research

A systematic review and meta-analysis of the effects of  supervised exercise therapy on modifiable cardiovascular risk factors in intermittent claudication
The objective of this study was to determine the effects of supervised exercise therapy (SET) on modifiable cardiovascular risk factors in IC patients.
Source: Journal of Vascular Surgery - February 15, 2019 Category: Surgery Authors: Sandra C.P. Jansen, Beatrijs B.N. Hoorweg, Sanne E. Hoeks, Marijn M.L. van den Houten, Marc R.M. Scheltinga, Joep A.W. Teijink, Ellen V. Rouwet Tags: Review article Source Type: research

Treatment Strategies for the Claudicant
Semin intervent Radiol 2018; 35: 435-442 DOI: 10.1055/s-0038-1676322Peripheral arterial disease (PAD) is a prevalent, morbid, and mortal disease. Claudication represents an early, yet common manifestation of PAD. A clinical history and physical examination combined with an ankle-brachial index can help make a diagnosis of claudication. Due to the polyvascular nature of the underlying atherosclerosis, PAD is often associated with heart disease and stroke. Although health implications of PAD derive from both its limb and cardiovascular manifestations, claudication is life-threatening, less limb-threatening. Medical modificat...
Source: Seminars in Interventional Radiology - February 5, 2019 Category: Radiology Authors: Pereira, Keith Tags: Review Article Source Type: research

Long-Term Effects of Bosentan on Cardiovascular Events in Hispanic Patients with Intermittent Claudication: Four-Year Follow-up of the CLAU Trial
ConclusionTreatment with bosentan in the early low-to-mild stages of PAD may prevent cardiovascular events and the need for lower limb revascularization in the Hispanic population.Trial Registration ClinicalTrials.gov identifier NCT25102012.
Source: American Journal of Cardiovascular Drugs - November 12, 2018 Category: Cardiology Source Type: research

Supra-aortic vessel reconstruction in total  arch replacement for acute type A dissection: Comparison of en bloc and separate graft techniques.
CONCLUSIONS: The modified en bloc technique could achieve comparable early and mid-term outcomes to the branched graft technique in patients undergoing TAR for ATAAD. This approach may be an alternative technique for ATAAD patients with intact supra-aortic arch vessels. PMID: 30377019 [PubMed - as supplied by publisher]
Source: Asian Journal of Surgery - October 27, 2018 Category: Surgery Authors: Lin Y, Ma WG, Zheng J, Xing XY, Pan XD, Zhu JM, Sun LZ Tags: Asian J Surg Source Type: research

Evaluation of health utility values for diabetic complications, treatment regimens, glycemic control and other subjective symptoms in diabetic patients using the EQ-5D-5L
ConclusionsThe utility decrement related to each diabetic complication varied with its severity and accompanying symptoms. Complex treatment regimens were independently associated with lower utility values. The utility decrement associated with diabetic complication and complex treatment regimens would be overestimated in the analysis without adjustment for glycemic control or other subjective symptoms.
Source: Acta Diabetologica - October 23, 2018 Category: Endocrinology Source Type: research

Cilostazol for treatment of cerebral infarction.
Authors: Noma K, Higashi Y Abstract INTRODUCTION: Stroke not only causes critical disability and death but is also a cause of anxiety with the possibility of secondary cardiovascular events including secondary ischemic stroke. Indeed, patients with a history of previous stroke have a high rate of stroke recurrence, indicating the clinical importance of secondary stroke prevention. Area of covered: This review provides an overview of the pooled evidence for cilostazol's use in the management of secondary stroke prevention. Among the various antiplatelet agents that are available, aspirin is the most frequently used ...
Source: Expert Opinion on Pharmacotherapy - September 14, 2018 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research

Atherosclerosis knowledge - diagnosis and management in primary care.
CONCLUSIONS: Our study demonstrates that GPs' knowledge about atherosclerosis disease varies significantly depending on disease location. GPs diagnose correctly but need to be backed up for their management of patients with atherosclerosis. PMID: 30047837 [PubMed - as supplied by publisher]
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - July 26, 2018 Category: Surgery Authors: Charasson M, Mahé G, Le Brun C, Jaquinandi V, Rossignol E, Le Faucheur A, Omarjee L Tags: Vasa Source Type: research

Endovascular Versus Open Surgical Intervention in Patients with Takayasu's Arteritis: A Meta-analysis
Although medical treatment has advanced, surgical treatment is needed to control symptoms of Takayasu's arteritis (TA), such as angina, stroke, hypertension, or claudication. Endovascular or open surgical intervention is performed; however, there are few comparative studies on these methods. This meta-analysis and systematic review aimed to examine the outcome of surgical treatment of TA.
Source: Journal of Vascular Surgery - June 21, 2018 Category: Surgery Authors: J.H. Jung, Y.H. Lee, G.G. Song, H.S. Jeong, J.-H. Kim, S.J. Choi Tags: Selected Abstract from the June Issue of the European Journal of Vascular and Endovascular Surgery Source Type: research

Endovascular Versus Open Surgical Intervention in Patients with Takayasu's Arteritis: A Meta-analysis.
CONCLUSION: This meta-analysis has shown a lower risk of restenosis with open surgical intervention than with endovascular intervention. Stroke was generally more common with open surgical intervention than with endovascular intervention. However, there were differences according to the location of the lesion, and the risk of stroke in open surgery is higher when the supra-aortic branches are involved rather than the renal arteries. PMID: 29622513 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - April 2, 2018 Category: Surgery Authors: Jung JH, Lee YH, Song GG, Jeong HS, Kim JH, Choi SJ Tags: Eur J Vasc Endovasc Surg Source Type: research

Endovascular Versus Open Surgical Intervention in Patients with Takayasu's Arteritis: A Meta-analysis
Although medical treatment has advanced, surgical treatment is needed to control symptoms of Takayasu's arteritis (TA), such as angina, stroke, hypertension, or claudication. Endovascular or open surgical intervention is performed; however, there are few comparative studies on these methods. This meta-analysis and systematic review aimed to examine the outcome of surgical treatment of TA.
Source: European Journal of Vascular and Endovascular Surgery - April 2, 2018 Category: Surgery Authors: Jae Hyun Jung, Young Ho Lee, Gwan Gyu Song, Han Saem Jeong, Jae-Hoon Kim, Sung Jae Choi Tags: Review Source Type: research

Peripheral arterial disease: Treatment.
Abstract Medical management of peripheral arterial disease (PAD) patients is aimed at limb symptom relief and reducing systemic major adverse events risk. For the first purpose: exercise therapy is recommended in case of claudication; multidisciplinary evaluation for surgical options is mandatory in case of critical limb ischaemia. Reducing cardiac and stroke risk can be achieved through: statin prescription in most of the cases; antiplatelet agents in symptomatic PAD patients; cardio-vascular risk factors control. PMID: 29273182 [PubMed - as supplied by publisher]
Source: Presse Medicale - December 19, 2017 Category: General Medicine Authors: Desormais I, Aboyans V, Pesteil F, Lacroix P Tags: Presse Med Source Type: research

Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk).
CONCLUSIONS : Patients with PAD are at high risk of cardiovascular events, and PCSK9 inhibition with evolocumab significantly reduced that risk with large absolute risk reductions. Moreover, lowering of low-density lipoprotein cholesterol with evolocumab reduced the risk of major adverse limb events. CLINICAL TRIAL REGISTRATION : URL: https://www.clinicaltrials.gov. Unique identifier: NCT01764633. PMID: 29133605 [PubMed - as supplied by publisher]
Source: Circulation - November 13, 2017 Category: Cardiology Authors: Bonaca MP, Nault P, Giugliano RP, Keech AC, Pineda AL, Kanevsky E, Kuder J, Murphy SA, Jukema JW, Lewis BS, Tokgozoglu L, Somaratne R, Sever PS, Pedersen TR, Sabatine MS Tags: Circulation Source Type: research

Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial
Publication date: Available online 10 November 2017 Source:The Lancet Author(s): Sonia S Anand, Jackie Bosch, John W Eikelboom, Stuart J Connolly, Rafael Diaz, Peter Widimsky, Victor Aboyans, Marco Alings, Ajay K Kakkar, Katalin Keltai, Aldo P Maggioni, Basil S Lewis, Stefan Störk, Jun Zhu, Patricio Lopez-Jaramillo, Martin O'Donnell, Patrick J Commerford, Dragos Vinereanu, Nana Pogosova, Lars Ryden, Keith A A Fox, Deepak L Bhatt, Frank Misselwitz, John D Varigos, Thomas Vanassche, Alvaro A Avezum, Edmond Chen, Kelley Branch, Darryl P Leong, Shrikant I Bangdiwala, Robert G Hart, Salim Yusuf Background Patients with periph...
Source: The Lancet - November 11, 2017 Category: General Medicine Source Type: research

Amputation Rates, Mortality, and Pre-operative Comorbidities in Patients Revascularised for Intermittent Claudication or Critical Limb Ischaemia: A Population Based Study.
CONCLUSION: The risk of amputation is particularly high during the first 6 months following revascularisation for CLI. IC patients have a benign course in terms of limb loss. Mortality in both IC and CLI patients is substantial. Revascularised CLI patients have different comorbidities from IC patients. PMID: 28797662 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - August 7, 2017 Category: Surgery Authors: Baubeta Fridh E, Andersson M, Thuresson M, Sigvant B, Kragsterman B, Johansson S, Hasvold P, Falkenberg M, Nordanstig J Tags: Eur J Vasc Endovasc Surg Source Type: research

Improvement of peripheral artery disease with Sildenafil and Bosentan combined therapy in a patient with limited cutaneous systemic sclerosis: A case report
We report a case of a 48-year-old Black woman, who developed severe left limb claudication and walking limitation following a left femoropopliteal bypass occlusion in 2014. She was a heavy smoker and had a history of right middle cerebral artery ischemic stroke and bilateral Raynaud phenomenon. Diagnoses: According to the American College of Rheumatology/European League Against Rheumatism-2013 criteria, diagnosis of limited cutaneous SSc was retained with macrovascular lesions. She was referred for investigation of left limb claudication on treadmill using transcutaneous oxygen pressure measurement during exercise to argu...
Source: Medicine - June 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Where did the clot go? An unusual complication of mechanical thrombectomy caused by malignancy related subclavian steal phenomenon in a patient with acute basilar artery occlusion
Subclavian steal is a relatively common vascular phenomenon usually caused by atherosclerotic disease. While symptoms are rare, arm claudication of the ipsilateral limb is most common, with paroxysmal symptoms of vertebrobasilar insufficiency (often exercise induced) being relatively uncommon. Here we present a case of brachial artery embolism during mechanical thrombectomy for basilar artery thrombosis, secondary to subclavian steal phenomenon. This atypical and potentially irreversible complication should be considered in patients with acute ischemic stroke undergoing neurointerventional management when subclavian steal ...
Source: Journal of NeuroInterventional Surgery - May 30, 2017 Category: Neurosurgery Authors: Randhawa, N., Squires, J. P., Heran, M. K. S., Mann, S. K. Tags: Electronic pages Source Type: research

Feasibility of a cardiovascular cohort in a Sub-Saharan Africa community: preliminary report of the pilot project TAHES (Tanv è Health Study) in Benin.
CONCLUSION: These preliminary results support the feasibility of establishing a cohort in Benin. It would require technical and resource support. PMID: 28498739 [PubMed - in process]
Source: Global Health Action - May 14, 2017 Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research

Relationship of Leukoaraiosis to Vascular Risk Factors and Lesion Type in Stroke Patients
Nonspecific periventricular white matter lucencies on computed tomograms (leukoaraiosis) were found in 49 (55%) of 89 stroke patients. We compared the vascular risk factors and the types of stroke with and without leukoaraiosis. Patients with leukoaraiosis were significantly older than those without it. The duration of hypertension was longer than those without leukoaraiosis. Mean diastolic blood pressure was associated with leukoaraiosis. No association was found with systolic blood pressure, diabetes mellitus, angina pectoris, myocardial infarction, heart failure, valvular disease and intermittent claudication. Patients ...
Source: Annals of Saudi Medicine - May 4, 2017 Category: Journals (General) Tags: ISSUE 2 Source Type: research

Walking training at the heart rate of pain threshold improves cardiovascular function and autonomic regulation in intermittent claudication: A randomized controlled trial
Conclusions In addition to increasing walking capacity, WT improved cardiovascular function and autonomic regulation in patients with IC.
Source: Journal of Science and Medicine in Sport - March 23, 2017 Category: Sports Medicine Source Type: research

Home, automated office, and conventional office blood pressure as predictors of cardiovascular risk
This study aimed to compare conventional office BP (OBP), HBP, and AOBP in order to evaluate their value in predicting CV events and deaths in hypertensives. We assessed 236 initially treatment na ïve hypertensives, examined between 2009 and 2013. The end points were any CV and non-CV event including mortality, myocardial infarction, coronary heart disease, hospitalization for heart failure, severe arrhythmia, stroke, and intermittent claudication.
Source: Journal of the American Society of Hypertension - February 3, 2017 Category: Cardiology Authors: Emmanuel A. Andreadis, Vasilios Papademetriou, Charalampia V. Geladari, George N. Kolyvas, Epameinondas T. Angelopoulos, Konstantinos N. Aronis Tags: Research Article Source Type: research

The Association between Residence Floor Level and Cardiovascular Disease: The Health and Environment in Oslo Study.
Conclusion. Floor level is positively associated with CVD, in Oslo. The best-supported explanation may be residual confounding by building height and SES. Another explanation, about the impact of atmospheric electricity, is also presented. The results underline a need to better understand the associations between residence floor level and CVD and multistory housing and CVD. PMID: 28053608 [PubMed - in process]
Source: Journal of Environmental and Public Health - January 6, 2017 Category: Environmental Health Tags: J Environ Public Health Source Type: research

Peripheral Revascularization in Patients With Peripheral Artery Disease With Vorapaxar: Insights From the TRA 2{degrees}P-TIMI 50 Trial
Conclusions Vorapaxar reduces peripheral revascularization in patients with PAD. This benefit of vorapaxar is directionally consistent across type of procedure and indication. (Trial to Assess the Effects of Vorapaxar [SCH 530348; MK-5348] in Preventing Heart Attack and Stroke in Patients With Atherosclerosis [TRA 2°P - TIMI 50] [P04737]; NCT00526474)
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - October 24, 2016 Category: Cardiology Authors: Bonaca, M. P., Creager, M. A., Olin, J., Scirica, B. M., Gilchrist, I. C., Murphy, S. A., Goodrich, E. L., Braunwald, E., Morrow, D. A. Tags: Peripheral Source Type: research

Short stature in men is associated with subclinical peripheral arterial disease.
CONCLUSIONS: Short stature in men is associated with subclinical PAD and lower ABI values. PMID: 27598046 [PubMed - as supplied by publisher]
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - September 6, 2016 Category: Surgery Authors: Heikkilä A, Venermo M, Kautiainen H, Arnio P, Korhonen P Tags: Vasa Source Type: research

Scallops, fenestrations, CHIMPS, and other monkey business
The coverage of branch vessels during thoracic endovascular aortic repair (TEVAR) with resultant end-organ ischemia is a limitation of endograft technology. Although coverage of the left subclavian artery (LSA) initially was thought to be safe (zone 2 TEVAR), experience has shown that LSA ischemia comes at the cost of permanent stroke and spinal cord injury and reversible complications of arm claudication and vertebrobasilar ischemia. Preserving flow to the LSA in the acute setting remains a clinical dilemma because the emergency nature of the procedure often precludes time-consuming efforts to preserve LSA flow.
Source: The Journal of Thoracic and Cardiovascular Surgery - July 29, 2016 Category: Cardiovascular & Thoracic Surgery Authors: S. Chris Malaisrie Tags: Editorial commentary Source Type: research

11-dehydro thromboxane B2 levels after percutaneous transluminal angioplasty in patients with peripheral arterial occlusive disease during a one year follow-up period.
In this study, 175 patients diagnosed with peripheral arterial occlusive disease (PAOD) and demonstrating short-distance claudication or ischemic rest pain, requiring PTA in either the iliac, femoral, or popliteal arteries, were enrolled. The excretion of 11-dehydro thromboxane B2 (TXB2) was measured in urine samples by high-performance liquid chromatography-mass spectrometry and recalculated based on the creatinine concentration. The urine samples were collected the morning prior to PTA, immediately following PTA and the day after PTA. All of the study subjects were then observed for a period of 12 months. Urine samples w...
Source: J Physiol Pharmacol - June 1, 2016 Category: Drugs & Pharmacology Authors: Maga P, Sanak M, Jawien J, Rewerska B, Maga M, Wachsmann A, Koziej M, Gregorczyk-Maga I, Nizankowski R Tags: J Physiol Pharmacol Source Type: research

Extracranial giant cell arteritis: A narrative review.
Abstract A systematic literature search was performed to summarise current knowledge on extracranial giant cell arteritis (GCA), i.e. large-artery involvement in patients with or without clinically apparent temporal arteritis (cranial GCA). Extracranial GCA is increasingly recognised, both in patients with cranial GCA and with solitary extracranial GCA, due to increased awareness among physicians and development of modern imaging modalities. The literature on the pathogenesis and histopathology of extracranial GCA is scarce. It is considered to be similar to cranial GCA. Patients with solitary extracranial GCA oft...
Source: The Netherlands Journal of Medicine - June 1, 2016 Category: Journals (General) Authors: Lensen KD, Voskuyl AE, Comans EF, van der Laken CJ, Smulders YM Tags: Neth J Med Source Type: research

Revascularisation plus supervised exercise is superior to supervised exercise alone for the treatment of intermittent claudication
This study was a multicentre (10 sites), parallel-design randomised controlled trial of supervised exercise plus endovascular revascularisation versus supervised exercise alone for IC.4 Patients with IC and one or more stenotic lesions at the aortoiliac and/or femoropopliteal level amenable to endovascular therapy were eligible. Supervised exercise was provided 2–3 times per week for 30–45 min per session for 3 months and then continued...
Source: Evidence-Based Medicine - May 23, 2016 Category: Internal Medicine Authors: Vemulapalli, S. Tags: Clinical trials (epidemiology), Drugs: cardiovascular system, Stroke, Interventional cardiology, Radiology, Clinical diagnostic tests Therapeutics/Prevention Source Type: research

Efficacy and Safety of Transbrachial Access for Iliac Endovascular Interventions
Conclusion: Brachial artery access enables endovascular treatment of iliac artery disease in the majority of patients, although an adjunctive transfemoral access may be required. However, the high incidences of access site complications and cerebral events remain a significant limitation of the transbrachial approach.
Source: Journal of Endovascular Therapy - May 11, 2016 Category: Surgery Authors: Stavroulakis, K., Usai, M. V., Torsello, G., Schwindt, A., Stachmann, A., Beropoulis, E., Bisdas, T. Tags: Lower Limb Interventions Source Type: research

ACR Responds to MEDCAC on Peripheral Arterial Disease Care for Seniors
Reston, VA — The American College of Radiology (ACR) — as a member of a coalition of leading medical societies — provided peripheral arterial disease (PAD) treatment recommendations to the Medicare Evidence Development Coverage Advisory Committee (MEDCAC). In addition, the coalition called for continued research in how to provide the best care for U.S. seniors with lower extremity PAD. “Identifying quality health care and impacting the treatment of a disease that affects millions of Americans are critical,” said Anne C. Roberts, MD, FACR, ACR vice president and co-author of the multisociety r...
Source: American College of Radiology - April 10, 2016 Category: Radiology Source Type: news

Recurrent Spells of Unresponsiveness Secondary to Bilateral Carotid Stenosis Caused by Giant Cell Arteritis (P4.373)
Conclusions: The presence of bilateral carotid stenosis in patients with GCA is strongly associated with future risk of neurologic deficits. A vertebrobasilar steal syndrome may be a manifestation of bilateral, severe carotid stenosis. It may be difficult to separate atherosclerotic lesions from vasculitic lesions related to GCA, however, the presence of localized focal stenosis with relatively healthy arteries above and below the lesions may point to a vasculitic process. Rigorous attention should be given to modification of atherosclerotic risk factors as well as recognizing and treating the rare manifestation of GCA.Dis...
Source: Neurology - April 4, 2016 Category: Neurology Authors: Wahba, M. Tags: Cerebrovascular Case Reports Source Type: research

A Case of Transient Global Amnesia: A Review and How It May Shed Further Insight into the Neurobiology of Delusions
Conclusion In closing, our patient’s episode of TGA combined with her emotional and perceptual response lends credence to the proposal of a “fear/paranoia” circuit in the genesis of paranoid delusions—a circuit incorporating amygdala, frontal, and parietal cortices. Here, neutral or irrelevant stimuli, thoughts, and percepts come to engender fear and anxiety, while dysfunction in frontoparietal circuitry engenders inappropriate social predictions and maladaptive inferences about the intentions of others.[54] Hippocampus relays information about contextual information based on past experiences and the current situat...
Source: Innovations in Clinical Neuroscience - April 1, 2016 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Behavioral and Cognitive Neurology Case Report Cognition Current Issue Dementia Medical Issues Neurologic Systems and Symptoms Psychiatry Schizophrenia delusions hippocampus neurobiology Transient global amnesia Source Type: research

Development of parallel graft for arch lesions.
CONCLUSION: The results of parallel graft in the aortic arch are promising, but of major concern is still the high rate of Type I endoleaks as well as the neurological complication rate, most probably due to catheter manipulation in patients with severe atherosclerotic arch lesions. PMID: 27029672 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Surgery - March 31, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Kolvenbach R, Rabin A, Karmeli R, Alpaslan A, Schwierz E Tags: J Cardiovasc Surg (Torino) Source Type: research

Surgical versus non-surgical treatment for lumbar spinal stenosis.
CONCLUSIONS: We have very little confidence to conclude whether surgical treatment or a conservative approach is better for lumbar spinal stenosis, and we can provide no new recommendations to guide clinical practice. However, it should be noted that the rate of side effects ranged from 10% to 24% in surgical cases, and no side effects were reported for any conservative treatment. No clear benefits were observed with surgery versus non-surgical treatment. These findings suggest that clinicians should be very careful in informing patients about possible treatment options, especially given that conservative treatment options...
Source: Cochrane Database of Systematic Reviews - January 29, 2016 Category: Journals (General) Authors: Zaina F, Tomkins-Lane C, Carragee E, Negrini S Tags: Cochrane Database Syst Rev Source Type: research

Stroke from an External Carotid: Lesion Pattern and Mechanisms
Traditionally, patients with symptomatic external carotid stenosis present with neck or face pain, retinal ischaemic symptoms or jaw claudication. and rarely as ipsilateral cerebrovascular events. In this present case, our patient suffered a stroke from a paradoxical embolism from the external carotid, without involvement of the internal carotid artery. A plaque ulceration of the external carotid’s origin was the cause of this cerebral emboli. Duplex ultrasound showed a pathological left external carotid, with a floating thrombus in the internal carotid.
Source: Annals of Vascular Surgery - January 20, 2016 Category: Surgery Authors: Kagan Nicolas, Lathelyse Hubert, Leclere Franck Marie, Marchand Etienne, Martinez Robert Source Type: research

Stroke in young adults and incidence rate in 280 patients according to their aetiological subtype.
CONCLUSIONS: Stroke in young adults is infrequent (6.1% of the total), but represents the highest frequency of cerebral infarcts of unusual aetiology (36%). We conclude that stroke in younger patients presents its own and differentiated clinical profile. PMID: 26726109 [PubMed - as supplied by publisher]
Source: Medicina Clinica - January 12, 2016 Category: Journals (General) Tags: Med Clin (Barc) Source Type: research

Endovascular repair of pseudoaneurysms after open surgery for aortic coarctation
CONCLUSIONS Endovascular treatment of post-coarctation pseudoaneurysms is feasible in elective and emergency cases, yielding durable results in the long term. Due to anatomical specifics, implantation may be challenging and requires careful procedural planning. On-site cardiothoracic surgery backup is essential in case open conversion is required.
Source: Interactive CardioVascular and Thoracic Surgery - December 26, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Kotelis, D., Bischoff, M. S., Rengier, F., Ruhparwar, A., Gorenflo, M., Böckler, D. Tags: Pericardium Adult Cardiac Source Type: research

A stroke of bad luck.
Abstract Giant cell arteritis is a common cause of headache in patients aged more than 50 years. It is an easy diagnosis to make if classical features, ie temporal headache, jaw claudication, visual symptoms, systemic symptoms of fever or weight loss with high erythrocyte sedimentation rate and anemia, are present. However, it may present atypically and stroke can be the presenting feature. A high index of suspicion is needed in atypical presentations such as stroke. Once a diagnosis is suspected it is imperative to start high dose steroids to prevent visual and neurological complications. PMID: 25468861 [PubMed - in process]
Source: Clinical Medicine - December 1, 2014 Category: Journals (General) Authors: Nagasayi S, White S, Joshi Y Tags: Clin Med Source Type: research

Prolonged P wave duration predicts stroke mortality among type 2 diabetic patients with prevalent non-major macrovascular disease
Conclusions: As an easily measurable factor P wave duration merits further studies with higher number of patients to evaluate its importance in the estimation of stroke risk in type 2 diabetic patients with PNMMVD.
Source: BMC Cardiovascular Disorders - November 25, 2014 Category: Cardiology Authors: Teemu VepsäläinenMarkku LaaksoSeppo LehtoAuni JuutilainenJuhani AiraksinenTapani Rönnemaa Source Type: research

Socioeconomic Position and Incidence of Ischemic Stroke in Denmark 2003-2012. A Nationwide Hospital-Based Study Stroke
Conclusions In Denmark, there is a strong relation between low socioeconomic position and risk for hospitalization for stroke. Lifestyle, as indicated by smoking, obesity, and alcohol consumption, and diabetes appears to increase the risk for stroke in people with lower socioeconomic position.
Source: JAHA:Journal of the American Heart Association - July 16, 2014 Category: Cardiology Authors: Andersen, K. K., Steding-Jessen, M., Dalton, S. O., Olsen, T. S. Tags: Stroke Source Type: research

Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
Conclusion: HZ is an independent risk factor for vascular disease in the UK population, particularly for stroke, TIA, and MI in subjects affected before the age of 40 years. In older subjects, better ascertainment of vascular risk factors and earlier intervention may explain the reduction in risk of stroke after HZ infection.
Source: Neurology - July 7, 2014 Category: Neurology Authors: Breuer, J., Pacou, M., Gautier, A., Brown, M. M. Tags: CORRECTED AND REPUBLISHED ARTICLES Source Type: research