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YouTube as a source of patient information for stroke: A content-quality and an audience engagement analysis
Stroke is the second leading cause of death worldwide following ischemic heart disease, and the fifth in the United States. The video-sharing database, YouTube, is the second most popular visited website with more than 2 billion users, thus it's increasingly being used as a medium for delivering health information.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Tomasz Szmuda, Ahmed Alkhater, Mohammed Albrahim, Eyad Alquraya, Shan Ali, Rakan Al Dunquwah, Pawe ł Słoniewski Source Type: research

Deiodinases, organic anion transporter polypeptide polymorphisms and symptoms of anxiety and depression after ischemic stroke
Mental disorders, such as anxiety and depression, are common after stroke. It was reported, that post-stroke anxiety cumulative incidence reached 57% within the first ten years after stroke was experienced.1 This mental health problem after stroke leads to impaired quality of life1 and poorer activity of daily living.2 Recent meta-analysis established, that the risk of stroke in a person with symptoms of anxiety is even higher compared to the risk of coronary heart disease or heart failure.3 Moreover, anxiety disorder comorbid with symptoms of depression after stroke was associated with increased lethal outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Saulius Taroza, Daiva Rastenyt ė, Julius Burkauskas, Aurelija Podlipskytė, Nijolė Kažukauskienė, Vaiva Patamsytė, Narseta Mickuvienė Source Type: research

Predictors of Recurrent Ischemic Stroke in Obese Patients With Type 2 Diabetes Mellitus: A Population-based Study
Each year, approximately 0.8 million people are estimated to experience a new or recurrent stroke, according to the 2019 report of the American Heart Association.1 In Malaysia, stroke is the third leading cause of death after ischemic heart disease (IHD) and pneumonia.2 Both obesity and diabetes are considered as the established independent risk factors for ischemic stroke.3 Type 2 diabetes mellitus (T2DM) was also found to be associated with an increase in all-cause as well as cardiovascular mortality following the stroke,4,5 and in a meta-analysis of 18 studies, patients with diabetes had a higher stroke recurrence as co...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Orwa Albitar, Sabariah Noor Harun, Nur Ezzati Abidin, Balamurugan Tangiisuran, Hadzliana Zainal, Irene Looi, Khairul Azmi Ibrahim, Norsima Nazifah Sidek, Keat Wei Loo, Keng Yee Lee, Zariah Abdul Aziz, Siti Maisharah Sheikh Ghadzi Source Type: research

Risk factors and pathogenic microorganism characteristics for pneumonia in convalescent patients with stroke: A retrospective study of 380 patients from a rehabilitation hospital
Stroke significantly impacts public health and ranks among the leading causes of death and disabilities, resulting in enormous costs measured in both health care resources and lost productivity. It results primarily from embolus or thrombosis for ischemic stroke and hypertension for hemorrhagic stroke, respectively [1]. In 2016, there were 5.5 million deaths and 116.4 million disability-adjusted life-years (DALYs) owed to stroke [2]. As reported, the impact of stroke on the Chinese population is more severe compared to average global levels, and the prevalence of stroke continues to surpass that of ischemic heart disease [3 –4].
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Jia Xu, Zhiling Yang Source Type: research

Stroke Awareness in Patients with Incident Stroke Compared to Patients without Stroke or Ischemic Heart Disease
Background: Stroke awareness is known to influence treatment seeking and risk reduction behavior, but there is limited data from Sri Lanka and South Asia. Aim: To describe stroke awareness in incident stroke patients and to compare with patients without stroke and/or ischemic heart disease (IHD) in a Sri Lankan tertiary-care center. Methods: We studied awareness of stroke in all incident stroke patients admitted to a tertiary-care center in Sri Lanka and compared with a group of age- and sex-matched patients without stroke and/or IHD, over 2 years.
Source: Journal of Stroke and Cerebrovascular Diseases - April 9, 2020 Category: Neurology Authors: Udaya Ranawaka, Chamila Mettananda, Chamila Thilakarathna, Anushka Peiris, Anuradhini Kasturiratna, Yasoma Tilakaratna Source Type: research

Acute Psychological Stress is a Trigger for Stroke: A Case-Crossover Study
Conventional risk factors for stroke that have been identified are mostly chronic diseases that explain much of the variation as to who develops stroke. However, these risk factors do not equip us with the means to predict when an event like stroke will occur. It has been observed that acute events like stroke and coronary heart disease are preceded by episodes of acute stress. The present study was undertaken to determine whether acute psychological stress is a potential triggering factor for the occurrence of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2020 Category: Neurology Authors: Manya Prasad, Pardeep Khanna, V.K. Katyal, Ramesh Verma Source Type: research

Early Prediction of One-Year Mortality in Ischemic and Haemorrhagic Stroke
The worldwide stroke incidence is 17 million per year,1 and 12 % of all deaths worldwide are caused by stroke making it the third leading cause of death after cancer and ischemic heart disease.2
Source: Journal of Stroke and Cerebrovascular Diseases - February 6, 2020 Category: Neurology Authors: Jacob Liljehult, Thomas Christensen, Karl Bang Christensen Source Type: research

Napping Once Or Twice A Week Could Lower Heart Attack & Stroke Risk, Study Finds
By Amy Woodyatt, CNN (CNN) — Some good news for nap fanatics — a new study has found that a daytime nap taken once or twice a week could lower the risk of heart attacks or strokes. Researchers from the University Hospital of Lausanne, Switzerland studied the association between napping frequency and duration and the risk of fatal and non-fatal cardiovascular disease complications. Tracking 3,462 people between the ages of 35 and 75 for just over five years, the report authors found that those who indulged in occasional napping — once or twice a week, for between five minutes to an hour — were 48% ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 10, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News Syndicated CBSN Boston CNN Heart Attack Stroke Source Type: news

Vegetarians May Be At Higher Risk Of Stroke, Study Finds
BOSTON (CBS) – Many people adopt a vegetarian lifestyle to help reduce their risk of cardiovascular disease, but a new study published in the BMJ finds people who avoid meat all together may be at a higher risk of stroke. Researchers in the U.K. looked at about 48 thousand adults over 18 years. They found that vegetarians, vegans, and pescatarians (people who eat fish but not meat) had a lower risk of ischemic heart disease, like heart attacks. But vegetarians had a 20% higher risk of stroke compared to meat eaters. It’s not clear why vegetarians may suffer more strokes. Perhaps it is due to lower levels of cer...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 5, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Stroke Vegetarian Source Type: news

Diet Drinks Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Diet Beverages Linked To Increased Stroke Risk & Heart Attacks
This study, as well as other research on the connection between diet beverages and vascular disease, is observational and cannot show cause and effect. That’s a major limitation, researchers say, as it’s impossible to determine whether the association is due to a specific artificial sweetener, a type of beverage or another hidden health issue. “Postmenopausal women tend to have higher risk for vascular disease because they are lacking the protective effects of natural hormones,” North Carolina cardiologist Dr. Kevin Campbell said, which could contribute to increased risk for heart disease and stroke...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - February 14, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News CNN Heart Attack Stroke Source Type: news

Midlife Orthostatic Hypotension May Increase Risk of Dementia, Stroke
People with orthostatic hypotension (an excessive drop in blood pressure when standing up that can lead to dizziness and fainting) in midlife may be more likely than those without the condition to develop stroke and dementia later in life, according to astudy inNeurology.“The presence of orthostasis, especially in midlife, might identify individuals in whom more careful monitoring or risk factor management might be warranted,” wrote lead author Andreea Rawlings, Ph.D., of the Johns Hopkins Bloomberg School of Public Health and colleagues.These findings come from an analysis of data from 11,709 participants without a hi...
Source: Psychiatr News - July 30, 2018 Category: Psychiatry Tags: Alzheimer's Alzheimer's risk factors dementia dizziness orthostatic hypotension stroke Source Type: research

Large-Scale Phenome-Wide Association Study of PCSK9 Variants Demonstrates Protection Against Ischemic Stroke Original Articles
Conclusions: This result represents the first genetic evidence in a large cohort for the protective effect of PCSK9 inhibition on ischemic stroke and corroborates exploratory evidence from clinical trials. PCSK9 inhibition was not associated with variables other than those related to LDL (low-density lipoprotein) cholesterol, atherosclerosis, and type 2 diabetes mellitus, suggesting that other effects are either small or absent.
Source: Circulation: Cardiovascular Genetics - July 11, 2018 Category: Cardiology Authors: Rao, A. S., Lindholm, D., Rivas, M. A., Knowles, J. W., Montgomery, S. B., Ingelsson, E. Tags: Cardiovascular Disease, Diabetes, Type 2, Genetic, Association Studies, Ischemic Stroke Original Articles Source Type: research

Stroke and Cardiovascular Outcomes in Patients With Carotid Disease Undergoing Transcatheter Aortic Valve Replacement Structural Heart Disease
Conclusions— CD is common among TAVR patients, present in 1 of 5. CD was not associated with an increased risk of stroke or mortality at 30 day or 1 year. Post-TAVR stroke seems to be because of mechanisms other than CD.
Source: Circulation: Cardiovascular Interventions - June 12, 2018 Category: Cardiology Authors: Kochar, A., Li, Z., Harrison, J. K., Hughes, G. C., Thourani, V. H., Mack, M. J., Matsouaka, R. A., Cohen, D. J., Peterson, E. D., Jones, W. S., Vemulapalli, S. Tags: Aortic Valve Replacement/Transcatheter Aortic Valve Implantation, Mortality/Survival, Cerebrovascular Disease/Stroke, Vascular Disease Structural Heart Disease Source Type: research

Patent Foramen Ovale Closure Versus Medical Therapy for Cryptogenic Ischemic Stroke Topical Review
Source: Stroke - May 25, 2018 Category: Neurology Authors: Jeffrey L. Saver, Heinrich P. Mattle, David Thaler Tags: Congenital Heart Disease, Treatment, Ischemic Stroke Topical Reviews Source Type: research

Long-Term Risk of Hemorrhagic Stroke in Young Patients With Congenital Heart Disease Clinical Sciences
Conclusions—The relative risk of hemorrhagic stroke among children and young adults with CHD was almost 8× higher than that of matched controls from the general population, although the absolute risk was low. The highest risk of ICH and SAH occurred in patients with severe nonconotruncal defects and coarctation of the aorta.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Kok Wai Giang, Zacharias Mandalenakis, Mikael Dellborg, Georgios Lappas, Peter Eriksson, Per-Olof Hansson, Annika Rosengren Tags: Epidemiology, Cerebrovascular Disease/Stroke, Cerebrovascular Malformations, Intracranial Hemorrhage Original Contributions Source Type: research

Clinical and Demographic Characteristics Associated With Suboptimal Primary Stroke and Transient Ischemic Attack Prevention Clinical Sciences
Conclusions—Knowing the patient characteristics predictive of missed opportunities for stroke prevention may help primary care identify and appropriately manage these patients. Improving the management of these groups may reduce their risk and potentially prevent large number of future strokes and TIAs in the population.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Grace M. Turner, Melanie Calvert, Max G. Feltham, Ronan Ryan, Samuel Finnikin, Tom Marshall Tags: Epidemiology, Primary Prevention, Hypertension, Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

Comments on Etiological Classification of Stroke in Patients with Chagas Disease Using TOAST, Causative Classification System TOAST, and ASCOD Phenotyping
We have read with great interest the article by Bezerra et  al,1 in which an etiological classification of stroke in patients with Chagas heart disease using different systems is presented. By studying a tertiary referral center population composed of 32 patients with Chagas disease with stroke, the authors were able to show that although cardioembolic str oke affects the majority of patients, atherosclerosis and small-vessel occlusion still were important causes of stroke in patients with this condition.
Source: Journal of Stroke and Cerebrovascular Diseases - February 21, 2018 Category: Neurology Authors: Reinaldo B. Bestetti, Renata Dellalibera-Joviliano, Luc élio B. Couto Tags: Letter to the Editor Source Type: research

Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease Brief Report
Background and Purpose—There is growing evidence about the importance of vitamin D for cardiovascular health. Therefore, we examined the relationship between dietary vitamin D intake and risk of mortality from stroke and coronary heart disease in Japanese population.Methods—A prospective study encompassing 58 646 healthy Japanese adults (23 099 men and 35 547 women) aged of 40 to 79 years in whom dietary vitamin D intake was determined via a self-administered food frequency questionnaire. The median follow-up period was 19.3 years (1989–2009). The hazard ratios and 95% confidence intervals of mortality were calcu...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Haytham A. Sheerah, Ehab S. Eshak, Renzhe Cui, Hironori Imano, Hiroyasu Iso, Akiko Tamakoshi Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Association of Osteopontin, Neopterin, and Myeloperoxidase With Stroke Risk in Patients With Prior Stroke or Transient Ischemic Attacks Clinical Sciences
Background and Purpose—Established risk factors do not fully identify patients at risk for recurrent stroke. The SPARCL trial (Stroke Prevention by Aggressive Reduction in Cholesterol Levels) evaluated the effect of atorvastatin on stroke risk in patients with a recent stroke or transient ischemic attack and no known coronary heart disease. This analysis explored the relationships between 13 plasma biomarkers assessed at trial enrollment and the occurrence of outcome strokes.Methods—We conducted a case–cohort study of 2176 participants; 562 had outcome strokes and 1614 were selected randomly from those without outcom...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Peter Ganz, Pierre Amarenco, Larry B. Goldstein, Henrik Sillesen, Weihang Bao, Gregory M. Preston, K. Michael A. Welch Tags: Biomarkers, Proteomics, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Direct Mechanical Intervention Versus Bridging Therapy in Stroke Patients Eligible for Intravenous Thrombolysis Clinical Sciences
Background and Purpose—Randomized controlled trials have shown that mechanical thrombectomy (MT) plus best medical treatment improves outcome in stroke patients with large-vessel occlusion in the anterior circulation. Whether direct MT is equally effective as bridging thrombolysis (intravenous thrombolysis plus MT) in intravenous thrombolysis eligible patients remains unclear.Methods—We compared clinical and radiological outcomes at 3 months in 249 bridging patients with 111 patients receiving direct MT for large-vessel occlusion anterior circulation stroke from 2 prospective registries (study period Essen: June 2012 t...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Sebastian Bellwald, Ralph Weber, Tomas Dobrocky, Hannes Nordmeyer, Simon Jung, Jeffrie Hadisurya, Pasquale Mordasini, Marie–Luise Mono, Christian P. Stracke, Hakan Sarikaya, Corrado Bernasconi, Klaus Berger, Marcel Arnold, Rene Chapot, Jan Gralla, U Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Off-Label Use of Direct Oral Anticoagulants in Intracerebral Hemorrhage Patients With Prosthetic Valves Controversies in Stroke
Source: Stroke - October 23, 2017 Category: Neurology Authors: Seemant Chaturvedi, Carlos A. Molina, Magdy H. Selim, Hans-Christoph Diener, Stefan H. Hohnloser Tags: Valvular Heart Disease, Ischemic Stroke Controversies in Stroke Source Type: research

Parvovirus B19 Infection in Children With Arterial Ischemic Stroke Brief Report
Conclusions—Using MassTag–polymerase chain reaction, we detected parvovirus B19—a virus known to infect erythrocytes and endothelial cells—in some cases of childhood arterial ischemic stroke. This approach can generate new, testable hypotheses about childhood stroke pathogenesis.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Heather J. Fullerton, Jorge M. Luna, Max Wintermark, Nancy K. Hills, Rafal Tokarz, Ying Li, Carol Glaser, Gabrielle A. DeVeber, W. Ian Lipkin, Mitchell S.V. Elkind Tags: Pediatrics, Ischemic Stroke Brief Reports Source Type: research

Relationship of Preexisting Cardiovascular Comorbidities to Newly Diagnosed Atrial Fibrillation After Ischemic Stroke Brief Report
Conclusions—Preexisting cardiovascular comorbidities underlie AF newly diagnosed after stroke. Consequently, these high-risk patients should be closely monitored for incident AF to facilitate an earlier diagnosis of AF and avoid stroke with appropriate thromboprophylaxis.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Arnaud Bisson, Nicolas Clementy, Alexandre Bodin, Denis Angoulvant, Dominique Babuty, Gregory Y.H. Lip, Laurent Fauchier Tags: Atrial Fibrillation, Ischemic Stroke Brief Reports Source Type: research

Plasma Retinol-Binding Protein 4 Levels and the Risk of Ischemic Stroke among Women
Plasma retinol-binding protein 4 (RBP4) levels have been associated with cardiovascular risk factors and risk of coronary heart disease, but little is known about the association between RBP4 and the risk of ischemic stroke. We hypothesized that elevated RBP4 levels would be associated with an increased risk of ischemic stroke among women.
Source: Journal of Stroke and Cerebrovascular Diseases - September 6, 2017 Category: Neurology Authors: Pamela M. Rist, Monik C. Jim énez, Shelley S. Tworoger, Frank B. Hu, JoAnn E. Manson, Qi Sun, Kathryn M. Rexrode Source Type: research

Serum matrix metalloproteinase-9 levels and prognosis of acute ischemic stroke
Conclusions: Higher serum MMP-9 levels in the acute phase of ischemic stroke were associated with increased risk of mortality and major disability, suggesting that serum MMP-9 could be an important prognostic factor for ischemic stroke.
Source: Neurology - August 21, 2017 Category: Neurology Authors: Zhong, C., Yang, J., Xu, T., Xu, T., Peng, Y., Wang, A., Wang, J., Peng, H., Li, Q., Ju, Z., Geng, D., Zhang, Y., He, J., For the CATIS Investigators Tags: Stroke prevention, Prognosis, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Cohort studies ARTICLE Source Type: research

Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults Clinical Sciences
Conclusions—Modifiable risk factors previously established in older populations also account for a large part of stroke in younger adults, with 4 risk factors explaining almost 80% of stroke risk.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Annette Aigner, Ulrike Grittner, Arndt Rolfs, Bo Norrving, Bob Siegerink, Markus A. Busch Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Stroke and Circulating Extracellular RNAs Clinical Sciences
Conclusions—This is the largest study of ex-RNAs in relation to stroke using an unbiased approach in an observational cohort and the first large study to examine human small noncoding RNAs beyond miRNAs. These results demonstrate that when studied in a large observational cohort, extracellular miRNAs are associated with stroke risk.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Eric Mick, Ravi Shah, Kahraman Tanriverdi, Venkatesh Murthy, Mark Gerstein, Joel Rozowsky, Robert Kitchen, Martin G. Larson, Daniel Levy, Jane E. Freedman Tags: Gene Expression & Regulation, Ischemic Stroke Original Contributions Source Type: research

Lipoprotein(a) Levels and Recurrent Vascular Events After First Ischemic Stroke Clinical Sciences
Conclusions—Elevated Lp(a) levels are associated with a higher risk for combined vascular event recurrence in patients with acute, first-ever ischemic stroke. This finding should be validated in larger, multicenter trials.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT01378468.
Source: Stroke - December 22, 2016 Category: Neurology Authors: Kristin S. Lange, Alexander H. Nave, Thomas G. Liman, Ulrike Grittner, Matthias Endres, Martin Ebinger Tags: Lipids and Cholesterol, Cardiovascular Disease, Risk Factors, Secondary Prevention, Ischemic Stroke Original Contributions Source Type: research

Rheumatic Mitral Valve Disease Is Associated With Worse Outcomes in Stroke Clinical Sciences
We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored. Data were obtained from a National Insurance Database. All hospitalized strokes between October 1, 2004, and January 31, 2013, were included in the current study. Characteristics and outcomes were compared for RMVD and non-RMVD patients. Logistic regression, propensity score matching, and multivariate models were used to assess study outcomes.Results...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wood, A. D., Mannu, G. S., Clark, A. B., Tiamkao, S., Kongbunkiat, K., Bettencourt-Silva, J. H., Sawanyawisuth, K., Kasemsap, N., Barlas, R. S., Mamas, M., Myint, P. K. Tags: Rheumatic Heart Disease, Valvular Heart Disease, Complications, Mortality/Survival, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Takotsubo-Like Myocardial Dysfunction in Ischemic Stroke Clinical Sciences
This study included 23 patients (0.42%). The mean age was 70.7±13.9 years, with predominance of women (73.9%) and typical pattern of Takotsubo-like myocardial dysfunction (91.3%). They were associated with short-term poor functional outcomes, including high mortality, neurological deterioration, and functional status at discharge, compared with those without (39.1% versus 2.4%, 47.8% versus 7.4%; and median [interquartile range], 5 [5–6] versus 3 [2–4]; all P
Source: Stroke - October 23, 2016 Category: Neurology Authors: Jung, J.-M., Kim, J.-G., Kim, J. B., Cho, K.-H., Yu, S., Oh, K., Kim, Y.-H., Choi, J.-Y., Seo, W.-K. Tags: Risk Factors, Cardiomyopathy, Prognosis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Aortic Valve Calcification and Risk of Stroke Brief Report
Conclusions—Although AVC is a common finding in middle-aged and elderly community-dwelling people, our results suggest that AVC is not associated with an increased risk of stroke.
Source: Stroke - October 23, 2016 Category: Neurology Authors: Bos, D., Bozorgpourniazi, A., Mutlu, U., Kavousi, M., Vernooij, M. W., Moelker, A., Franco, O. H., Koudstaal, P. J., Ikram, M. A., van der Lugt, A. Tags: Epidemiology, Valvular Heart Disease, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease Clinical Sciences
Conclusions— Whereas carotid plaque thickness and stenosis are associated with the history of ischemic stroke and CHD, carotid intraplaque hemorrhage is associated with ischemic stroke, but not with CHD, providing novel insights into the pathogenesis of cardiovascular events.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Selwaness, M., Bos, D., van den Bouwhuijsen, Q., Portegies, M. L. P., Ikram, M. A., Hofman, A., Franco, O. H., van der Lugt, A., Wentzel, J. J., Vernooij, M. W. Tags: Cardiovascular Disease, Epidemiology, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Atherosclerosis Clinical Sciences Source Type: research

Direct Mechanical Intervention Versus Combined Intravenous and Mechanical Intervention in Large Artery Anterior Circulation Stroke: A Matched-Pairs Analysis Clinical Sciences
Conclusions— In patients with large anterior circulation stroke, direct mechanical intervention seems to be equally effective as bridging thrombolysis. A randomized trial comparing direct MT with bridging therapy is warranted.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Broeg-Morvay, A., Mordasini, P., Bernasconi, C., Buhlmann, M., Pult, F., Arnold, M., Schroth, G., Jung, S., Mattle, H. P., Gralla, J., Fischer, U. Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Treatment, Ischemic Stroke Clinical Sciences Source Type: research

Preexisting Heart Disease Underlies Newly Diagnosed Atrial Fibrillation After Acute Ischemic Stroke Clinical Sciences
Conclusions— Stroke patients with nAF and with kAF share common cardiovascular risk factors, have similar echocardiographic findings and suffer equally severe strokes. We conclude that preexisting heart disease is the major cause of AF that is first diagnosed after stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Rizos, T., Horstmann, S., Dittgen, F., Tager, T., Jenetzky, E., Heuschmann, P., Veltkamp, R. Tags: Atrial Fibrillation, Echocardiography, Ischemic Stroke Clinical Sciences Source Type: research

Plasma D-Dimer and Incident Ischemic Stroke and Coronary Heart Disease: The Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— A higher basal plasma d-dimer concentration in the general population is a risk marker for ischemic stroke, especially cardioembolic stroke.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Folsom, A. R., Gottesman, R. F., Appiah, D., Shahar, E., Mosley, T. H. Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Acute Coronary Syndromes Clinical Sciences Source Type: research

Functional Gain After Inpatient Stroke Rehabilitation: Correlates and Impact on Long-Term Survival Brief Reports
Conclusions— Several factors are independently associated with functional gain after SR. Our findings strongly suggest that the magnitude of functional improvement is a powerful predictor of long-term mortality in patients admitted for SR.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Scrutinio, D., Monitillo, V., Guida, P., Nardulli, R., Multari, V., Monitillo, F., Calabrese, G., Fiore, P. Tags: Other Stroke Treatment - Medical Brief Reports Source Type: research

Premature Ventricular Complexes on Screening Electrocardiogram and Risk of Ischemic Stroke Brief Reports
Conclusions— PVCs are common on routine screening ECGs and are associated with an increased risk of ischemic stroke.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Agarwal, S. K., Chao, J., Peace, F., Judd, S. E., Kissela, B., Kleindorfer, D., Howard, V. J., Howard, G., Soliman, E. Z. Tags: Electrocardiology, Embolic stroke, Epidemiology Brief Reports Source Type: research

Community-Based Case-Control Study of Childhood Stroke Risk Associated With Congenital Heart Disease Clinical Sciences
Conclusions— CHD is an important childhood stroke risk factor. Children who undergo CHD surgery remain at elevated risk outside the perioperative period and would benefit from optimized long-term stroke prevention strategies.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Fox, C. K., Sidney, S., Fullerton, H. J. Tags: Pediatric and congenital heart disease, including cardiovascular surgery, Risk Factors for Stroke, Stroke in Children and the Young, Epidemiology Clinical Sciences Source Type: research

Antithrombotic Therapy After Acute Ischemic Stroke in Patients With Atrial Fibrillation Clinical Sciences
Conclusions— Contrary to current guidelines, 30% of patients with atrial fibrillation and recent IS are not prescribed any OAC therapy on discharge, whereas a further 30% are prescribed combination OAC and antiplatelet therapy. Combination OAC and antiplatelet therapy in patients at high cardiovascular risk requires evaluation in clinical trials, particularly with the newer OACs, given their more favorable risk–benefit ratio compared with warfarin.
Source: Stroke - November 24, 2014 Category: Neurology Authors: McGrath, E. R., Kapral, M. K., Fang, J., Eikelboom, J. W., Conghaile, A. O., Canavan, M., O'Donnell, M. J., on behalf of the Investigators of the Ontario Stroke Registry Tags: Secondary prevention, Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs Clinical Sciences Source Type: research

Nontraditional Serum Lipid Variables and Recurrent Stroke Risk Clinical Sciences
Conclusions— Of various nontraditional lipid variables, elevated baseline triglycerides/HDL-C and total cholesterol/HDL-C ratios predict future vascular risk after a stroke, but only elevated triglycerides/HDL-C ratio is related to risk of recurrent stroke. Future studies should assess the role of triglycerides/HDL-C as a potential therapeutic target for global vascular risk reduction after stroke.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Park, J.-H., Lee, J., Ovbiagele, B. Tags: Other Stroke Treatment - Medical Clinical Sciences Source Type: research

Sickle Cell Trait and Incident Ischemic Stroke in the Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— We observed an increased risk of ischemic stroke in blacks with SCT. Further investigation of the incidence and pathophysiology of stroke in patients with SCT is warranted.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Caughey, M. C., Loehr, L. R., Key, N. S., Derebail, V. K., Gottesman, R. F., Kshirsagar, A. V., Grove, M. L., Heiss, G. Tags: Genetics of Stroke, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Social Network, Social Support, and Risk of Incident Stroke: Atherosclerosis Risk in Communities Study Clinical Sciences
Conclusions— In this sample of US community-dwelling men and women, having a small social network was associated with excess risk of incident stroke. As with other cardiovascular conditions, having a small social network may be associated with a modestly increased risk of incident stroke.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Nagayoshi, M., Everson-Rose, S. A., Iso, H., Mosley, T. H., Rose, K. M., Lutsey, P. L. Tags: Behavioral/psychosocial - stroke Clinical Sciences Source Type: research

Effect of High-Dose Atorvastatin on Renal Function in Subjects With Stroke or Transient Ischemic Attack in the SPARCL Trial Clinical Sciences
Conclusions— This post hoc analysis suggests that atorvastatin treatment may improve renal function in patients with prior stroke or transient ischemic attack with and without chronic kidney disease, and that atorvastatin treatment may prevent eGFR decline in patients with stroke and diabetes mellitus. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00147602.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Amarenco, P., Callahan, A., Campese, V. M., Goldstein, L. B., Hennerici, M. G., Messig, M., Sillesen, H., Welch, K. M. A., Wilson, D. J., Zivin, J. A. Tags: Lipids, Secondary prevention, Cerebrovascular disease/stroke Clinical Sciences Source Type: research

Coronary Artery Calcification, Intima-Media Thickness, and Ankle-Brachial Index Are Complementary Stroke Predictors Clinical Sciences
Conclusions— CAC, CIMT, and ABI provide complementary information about stroke risk. ABI, which is distinctive in a small subpopulation, had the highest and CIMT, which is distributed across a larger range of values, had the lowest predictive value.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Gronewold, J., Bauer, M., Lehmann, N., Mahabadi, A. A., Kalsch, H., Weimar, C., Berger, K., Moebus, S., Jockel, K.-H., Erbel, R., Hermann, D. M., on behalf of the Heinz Nixdorf Recall Study Investigative Group Tags: Imaging, Computerized tomography and Magnetic Resonance Imaging, Doppler ultrasound, Transcranial Doppler etc., Risk Factors for Stroke Clinical Sciences Source Type: research

Assessing the Performance of the Framingham Stroke Risk Score in the Reasons for Geographic and Racial Differences in Stroke Cohort Clinical Sciences
Conclusions— Although higher FSRS was associated with higher stroke risk, the FSRS overestimated the observed stroke rates in this study, particularly in certain subgroups. This may be because of temporal declines in stroke rates, secular trends in prevention treatments, or differences in populations studied. More accurate estimates of event rates are critical for planning research, including clinical trials, and targeting health-care efforts.
Source: Stroke - May 27, 2014 Category: Neurology Authors: McClure, L. A., Kleindorfer, D. O., Kissela, B. M., Cushman, M., Soliman, E. Z., Howard, G. Tags: Risk Factors for Stroke Clinical Sciences Source Type: research

N-Terminal Pro-B-type Natriuretic Peptide and Stroke Risk: The Reasons for Geographic and Racial Differences in Stroke Cohort Clinical Sciences
Conclusions— NT-proBNP was a major independent risk marker for stroke. Considering this and other data for stroke, coronary disease, and atrial fibrillation, the clinical use of NT-proBNP measurement in primary prevention settings should be considered.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Cushman, M., Judd, S. E., Howard, V. J., Kissela, B., Gutierrez, O. M., Jenny, N. S., Ahmed, A., Thacker, E. L., Zakai, N. A. Tags: Acute Cerebral Infarction, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

Incident Stroke Is Associated With Common Carotid Artery Diameter and Not Common Carotid Artery Intima-Media Thickness Clinical Sciences
Conclusions— Although common carotid IMT is not associated with stroke, interadventitial diameter of the common carotid artery is independently associated with first-time incident ischemic stroke even after adjusting for IMT. Our hypothesis that this is in part attributable to the effects of exposure to blood pressure needs confirmation by other studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00063440.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Polak, J. F., Sacco, R. L., Post, W. S., Vaidya, D., Arnan, M. K., O'Leary, D. H. Tags: Cerebrovascular disease/stroke, Risk Factors, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research