Query: stroke

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Condition: Overactive Bladder

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Total 18 results found since Jan 2013.

Electroacupuncture for post-stroke overactive bladder: a multi-centre pilot randomized controlled trial.
CONCLUSION: A six-session EA treatment was feasible and appeared to reduce OAB symptoms in post-stroke patients. Further fully powered trials are warranted to confirm the efficacy of EA for those with post-stroke OAB. PMID: 32646228 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - July 8, 2020 Category: Complementary Medicine Authors: Chen H, Wang C, Zhou M, Yan Chan P, Lo Yam L, Lok Lam W, Leung KP, Li SW, Tsang WY, Fung-Leung Ng B, Tat-Chi Ziea E, Yeung WF, Lao L Tags: Acupunct Med Source Type: research

New clinical trial examines a potential noninvasive solution for overactive bladders
(University of Southern California - Health Sciences) Keck Medicine of USC urologists are launching a clinical trial to evaluate the effectiveness of spinal cord stimulation in patients with an overactive bladder due to neurological conditions, such as a spinal cord injury or stroke, and idiopathic (unknown) causes.
Source: EurekAlert! - Medicine and Health - March 10, 2020 Category: International Medicine & Public Health Source Type: news

Noninvasive spinal neuromodulation to map and augment lower urinary tract function in rhesus macaques.
Abstract Dysfunction of the lower urinary tract (LUT) is prevalent in neurological disorders, including multiple sclerosis, stroke, spinal cord injury and neurodegenerative conditions. Common symptoms include urgency, incontinence, and urinary retention. Recent advances in neuromodulation have resulted in improved treatments for overactive bladder symptoms of urgency, frequency, and nocturia. However, there are presently no treatments available for the induction of voiding to overcome urinary retention. We demonstrate that transcutaneous spinal cord stimulation (TSCS), a non-invasive intervention, applied over the...
Source: Experimental Neurology - August 6, 2019 Category: Neurology Authors: Havton LA, Christe KL, Edgerton VR, Gad PN Tags: Exp Neurol Source Type: research

Efficacy of trazodone for treating paroxysmal sympathetic hyperactivity presenting after thalamic hemorrhage: A case report.
Authors: Morinaga Y, Nii K, Sakamoto K, Inoue R, Mitsutake T, Hanada H Abstract Paroxysmal sympathetic hyperactivity (PSH) is a clinical condition characterized by abnormal paroxysmal surges in sympathetic nervous system activity. PSH is known to occur after severe head injury and hypoxic encephalopathy. Cases of PSH that develop after stroke have been reported worldwide; however, PSH is not commonly reported in the field of stroke research in Japan. Some studies have suggested that gabapentin may improve the symptoms of PSH. To our knowledge, this is the first case report demonstrating the efficacy of trazodone fo...
Source: Drug Discoveries and Therapeutics - July 23, 2019 Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research

Interest of transcranial stimulation in pelvic and perineal disorders.
CONCLUSION: Data from the literature suggest that transcranial stimulation is a noninvasive treatment that may have a role in the management of pelvic and perineal disorders. Its promising field of action would require prospective and randomized studies on a larger scale. PMID: 31036483 [PubMed - as supplied by publisher]
Source: Progres en Urologie - May 2, 2019 Category: Urology & Nephrology Tags: Prog Urol Source Type: research

Neuroanatomical correlates between stroke lesions and urinary disorders: A narrative review.
CONCLUSION: A few cerebral areas damaged by stroke seem to be linked to certain urinary troubles, but new studies with a higher methodological quality are required to confirm this result. PMID: 30527571 [PubMed - as supplied by publisher]
Source: Progres en Urologie - December 13, 2018 Category: Urology & Nephrology Tags: Prog Urol Source Type: research

Effectiveness of neuromuscular electrical stimulation therapy in patients with urinary incontinence after stroke: A randomized sham controlled trial
This study aimed to evaluate the effectiveness of neuromuscular electrical stimulation (NMES) therapy in patients with urinary incontinence after stroke (UIAS). Methods: A total of 82 patients with UIAS were randomly assigned to 2 groups that received NMES therapy (NMES group) or sham NMES (sham group) for 10 weeks. The primary efficacy endpoints were measured by urodynamic values, and Overactive Bladder Symptom Score (OABSS). The secondary efficacy endpoints were assessed by International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) score, Barthel Index (BI) scale, and adverse events. All outcomes we...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research

Improvement in overactive bladder symptoms in patients using functional electrical stimulation of the common peroneal nerve for walking.
CONCLUSION: The results of this exploratory study suggest that functional electrical stimulation use does improve overactive bladder symptoms in people with multiple sclerosis. Further exploration is needed to study this association and explore whether the mechanism is similar to that of percutaneous tibial nerve stimulation, a recognized treatment for the overactive bladder. PMID: 29909652 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - June 1, 2018 Category: Rehabilitation Authors: Hare N, Georgopoulos P, Philips KE, Johnson JE, Seary C, Panicker JN, Stevenson VL Tags: Clin Rehabil Source Type: research

Cardiovascular Safety of the β3 -Adrenoceptor Agonist Mirabegron and the Antimuscarinic Agent Solifenacin in the SYNERGY Trial.
Abstract There have been concerns that treatment of overactive bladder with β3 -adrenoceptor agonists may potentially have detrimental cardiovascular (CV) side effects. We evaluated the CV safety of mirabegron, a β3 -adrenoceptor agonist, alone and in combination therapy with the antimuscarinic agent solifenacin. The SYNERGY trial was a multinational, multicenter, randomized, double-blind, parallel-group, placebo and active-controlled phase 3 trial. Patients were randomized to receive solifenacin 5 mg + mirabegron 50 mg (combination 5 + 50 mg), solifenacin 5 mg + mirabegron 25 mg (combination 5 + 2...
Source: The Journal of Clinical Pharmacology - April 12, 2018 Category: Drugs & Pharmacology Authors: White WB, Chapple C, Gratzke C, Herschorn S, Robinson D, Frankel J, Ridder A, Stoelzel M, Paireddy A, van Maanen R, Weber MA Tags: J Clin Pharmacol Source Type: research

Comparison of cardiovascular events among treatments for overactive bladder: a Danish nationwide cohort study
ConclusionsWe did not identify differences in the risk of cardiovascular events or mortality among users of individual antimuscarinic OAB drugs.
Source: European Journal of Clinical Pharmacology - November 13, 2017 Category: Drugs & Pharmacology Source Type: research

A questionnaire survey to assess lower urinary tract symptoms in patients with chronic stroke
CONCLUSIONSStorage symptom is associated with not only neurological deficits but also sex and the presence of general diseases, whereas voiding symptom is influenced by physical activity in patients with chronic stroke. Therefore, lower urinary tract symptoms should be carefully monitored and physical rehabilitation should also be considered in patients with stroke.
Source: Neurourology and Urodynamics - February 6, 2017 Category: Urology & Nephrology Authors: Minoru Miyazato, Takeshi Tana, Akira Higa, Kiyoshi Wakugami, Takashi Tokashiki, Hirokuni Sakima, Aiwa Maehara, Asuka Ashikari, Takuma Oshiro, Yusuke Ohya, Seiichi Saito Tags: ORIGINAL CLINICAL ARTICLE Source Type: research

Nocturia indicates a poor health status and increases mortality in male patients with type 2 diabetes mellitus
Conclusions The presence of nocturia was associated with erectile dysfunction, systemic vascular events, higher mortality, and indicated poor health in male with type 2 diabetic mellitus.
Source: International Urology and Nephrology - May 6, 2016 Category: Urology & Nephrology Source Type: research

Effects of Transcutaneous Electrical Nerve Stimulation at Two Frequencies on Urinary Incontinence in Poststroke Patients: A Randomized Controlled Trial
The objective of this study was to compare the effects of two frequencies of transcutaneous electrical nerve stimulation (TENS) on urinary incontinence caused by stroke. Methods: Eighty-one patients with poststroke urinary incontinence were recruited and randomized into the following three groups with a 1:1 ratio: a 20-Hz TENS group, a 75-Hz TENS group, and a no-treatment control group (n = 27 per group). TENS currents were biphasic square waves with pulse durations of 150 μsecs and pulse frequencies of 20 Hz or 75 Hz and were applied for 30 mins once per day for 90 days. The positive electrodes were placed in the region...
Source: American Journal of Physical Medicine and Rehabilitation - February 24, 2016 Category: Rehabilitation Tags: Original Research Article Source Type: research

Effects of Transcutaneous Electrical Nerve Stimulation at Two Frequencies on Urinary Incontinence in Poststroke Patients: A Randomized Controlled Trial.
CONCLUSIONS: Twenty-hertz TENS improved incontinence symptoms and promoted activities of daily living better than 75-Hz TENS. These results will aid future research regarding TENS parameters. PMID: 26259053 [PubMed - as supplied by publisher]
Source: Medical Physics - August 7, 2015 Category: Physics Authors: Liu Y, Xu G, Luo M, Teng HF Tags: Am J Phys Med Rehabil Source Type: research

Research Findings on Overactive Bladder
Several physiopathologic conditions lead to the manifestation of overactive bladder (OAB). These conditions include ageing, diabetes mellitus, bladder outlet obstruction, spinal cord injury, stroke and brain injury, Parkinson's disease, multiple sclerosis, interstitial cystitis, stress and depression. This review has discussed research findings in human and animal studies conducted on the above conditions. Several structural and functional changes under these conditions have not only been observed in the lower urinary tract, but also in the brain and spinal cord. Significant changes were observed in the following areas: ne...
Source: Current Urology - May 20, 2015 Category: Urology & Nephrology Source Type: research

Media dementia scare over hay fever and sleep drugs
Conclusion This large US prospective cohort study suggests a link between those taking high levels of anticholinergic medicines for more than three years and developing dementia in adults over 65. The main statistically significant finding was in a group taking the equivalent of any of the following medications daily for more than three years: xybutynin chloride, 5mg chlorpheniramine maleate, 4mg olanzapine, 2.5mg meclizine hydrochloride, 25mg doxepin hydrochloride, 10mg These are not unrealistic doses of medicine, so the results may be applicable to a significant proportion of older adults. The main lim...
Source: NHS News Feed - January 27, 2015 Category: Consumer Health News Tags: Medication Neurology Source Type: news

Survey and Risk Factors for Lower Urinary Tract Storage Symptoms in Middle ‐Aged and Older Stroke Patients in Urban China
ConclusionsOur study identified not only putative risk factors for LUTS in middle‐aged and elderly stroke patients, but genuine factors including snoring, living environment and educational background that increased the odds of storage symptoms as well. We identified that regular exercise and living with their children were protective factors for storage symptoms in stroke patients.
Source: LUTS: Lower Urinary Tract Symptoms - November 17, 2014 Category: Urology & Nephrology Authors: Yudong TIAN, Yanbin GUAN, Jianguo WEN, Xiaoping SHANG, Jinsheng LI, Yan WANG Tags: ORIGINAL ARTICLE Source Type: research

Survey and Risk Factors for Lower Urinary Tract Storage Symptoms in Middle‐Aged and Older Stroke Patients in Urban China
ConclusionsOur study identified not only putative risk factors for LUTS in middle‐aged and elderly stroke patients, but genuine factors including snoring, living environment and educational background that increased the odds of storage symptoms as well. We identified that regular exercise and living with their children were protective factors for storage symptoms in stroke patients.
Source: LUTS: Lower Urinary Tract Symptoms - September 1, 2014 Category: Urology & Nephrology Authors: Yudong TIAN, Yanbin GUAN, Jianguo WEN, Xiaoping SHANG, Jinsheng LI, Yan WANG Tags: ORIGINAL ARTICLE Source Type: research