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Total 3278 results found since Jan 2013.

Certain pre-existing conditions may double, triple mortality risk for COVID-19
(Penn State) A large, international study of COVID-19 patients confirmed that cardiovascular disease, hypertension, diabetes, congestive heart failure, chronic kidney disease, stroke and cancer can increase a patient's risk of dying from the virus.
Source: EurekAlert! - Medicine and Health - October 8, 2020 Category: International Medicine & Public Health Source Type: news

Vitamin C: historical perspectives and heart failure
AbstractVitamin C (Vit C) is an ideal antioxidant as it is easily available, water soluble, very potent, least toxic, regenerates other antioxidants particularly Vit E, and acts as a cofactor for different enzymes. It has received much attention due to its ability in limiting reactive oxygen species, oxidative stress, and nitrosative stress, as well as it helps to maintain some of the normal metabolic functions of the cell. However, over 140 clinical trials using Vit C in different pathological conditions such as myocardial infarction, gastritis, diabetes, hypertension, stroke, and cancer have yielded inconsistent results....
Source: Heart Failure Reviews - October 8, 2020 Category: Cardiology Source Type: research

Randomized Trial Evaluation of Benefits and Risks of Menopausal Hormone Therapy Among Women Aged 50-59.
Abstract The health benefits and risks of menopausal hormone therapy among women aged 50-59 years are examined in the Women's Health Initiative randomized, placebo-controlled trials using long-term follow-up data and a parsimonious statistical model that leverages data from older participants to increase precision. These trials enrolled 27,347 healthy post-menopausal women aged 50-79 at 40 U.S. clinical centers during 1993-1998, including 10,739 post-hysterectomy participants in a trial of conjugated equine estrogens, and 16,608 participants with uterus in the trial of these estrogens plus medroxyprogesterone acet...
Source: Am J Epidemiol - October 7, 2020 Category: Epidemiology Authors: Prentice RL, Aragaki AK, Chlebowski RT, Rossouw JE, Anderson GL, Stefanick ML, Wactawski-Wende J, Kuller LH, Wallace R, Johnson KC, Shadyab AH, Gass M, Manson JAE Tags: Am J Epidemiol Source Type: research

Isolated oculomotor nerve palsy as a manifestation of diffuse large B cell lymphoma: A case report.
Authors: Khaleefah MM, Narayanan S, Dallal HAA, Jones CM, Friedland RP, Palade AE, Remmel KS, Shah JJ Abstract An isolated third nerve palsy presenting as the primary manifestation of a lymphoma is rare, with only few cases having been described. The present study reports an unusual case of a healthy 67-year old male diagnosed with isolated right oculomotor nerve palsy (ONP), who was found to have an underlying B cell lymphoma. The patient's medical records were accessed upon consent. A thorough physical examination, including stroke and infections work-ups were performed. A chest computerized tomography (CT), brai...
Source: Oncology Letters - October 6, 2020 Category: Cancer & Oncology Tags: Oncol Lett Source Type: research

Efficacy of Six Plants of Apiaceae Family for Body Weight Management: A Review from the Perspective of Modern and Traditional Persian Medicine.
CONCLUSION: Since the TPM is a rich source of information about the medicinal properties and effects of medicinal plants, investigating the therapeutic effects of plants from the perspective of TPM can represents the vision of a new horizon in the treatment of many diseases. PMID: 33023434 [PubMed - as supplied by publisher]
Source: Current Drug Discovery Technologies - October 6, 2020 Category: Drugs & Pharmacology Authors: Rameshk M, Kalantari-Khandani S Tags: Curr Drug Discov Technol Source Type: research

Clinacanthus nutans Mitigates Neuronal Death and Reduces Ischemic Brain Injury: Role of NF- κB-driven IL-1β Transcription
AbstractNeuroinflammation has been shown to exacerbate ischemic brain injury, and is considered as a prime target for the development of stroke therapies.Clinacanthus nutans Lindau (C. nutans) is widely used in traditional medicine for treating insect bites, viral infection and cancer, due largely to its anti-oxidative and anti-inflammatory properties. Recently, we reported that an ethanol extract from the leaf ofC. nutans could protect the brain against ischemia-triggered neuronal death and infarction. In order to further understand the molecular mechanism(s) for its beneficial effects, two experimental paradigms, namely,...
Source: NeuroMolecular Medicine - October 5, 2020 Category: Neurology Source Type: research

Causal inference and evidence-based recommendations in occupational health and safety research
In this issue of the Journal, a group of distinguished Nordic researchers, led by Anne Helene Garde and including four of our Associated Editors, present a discussion paper that originated from a workshop and provides detailed recommendations on night shift work (1). The recommendations are very clear: to protect workers ’ health, night shift schedules should have: (i) ≤3 consecutive night shifts; (ii) shift intervals of ≥11 hours; and (iii) ≤9 hours shift duration. For pregnant women, night work should be limited to one shift per week. The authors acknowledge that under circumstances allowing better possibi lities...
Source: Scandinavian Journal of Work, Environment and Health - October 2, 2020 Category: Occupational Health Tags: Editorial Source Type: research

D-dimer level in COVID-19 infection: a systematic review.
Authors: Rostami M, Mansouritorghabeh H Abstract INTRODUCTION: COVID-19 disease has spread worldwide from December 2019 to the present day; the early stage of this disease can be associated with high D-dimer, prolonged PT, and elevated levels of fibrinogen, indicating activation of coagulation pathways and thrombosis. In this article, we analyze the levels of D-dimer in patients with COVID-19. AREA COVERED: In the current study, three databases, PubMed, Scopus, Web of Science, searched using related keywords and information extracted from articles such as location, sample size, gender, age, coagulation test val...
Source: Expert Review of Hematology - October 1, 2020 Category: Hematology Tags: Expert Rev Hematol Source Type: research

Association Between Immune Checkpoint Inhibitors with Cardiovascular Events and Atherosclerotic Plaque.
Conclusions: Cardiovascular events were higher after initiation of ICIs, potentially mediated by accelerated progression of atherosclerosis. Optimization of cardiovascular risk factors and increased awareness of cardiovascular risk, prior to, during and after treatment, should be considered among patients on an ICI. PMID: 33003973 [PubMed - as supplied by publisher]
Source: Circulation - October 1, 2020 Category: Cardiology Authors: Drobni ZD, Alvi RM, Taron J, Zafar A, Murphy SP, Rambarat PK, Mosarla RC, Lee C, Zlotoff DA, Raghu VK, Hartmann SE, Gilman HK, Gong J, Zubiri L, Sullivan RJ, Reynolds KL, Mayrhofer T, Zhang L, Hoffmann U, Neilan TG Tags: Circulation Source Type: research

Potentially fatal complications of systemic air embolism after computed tomography ‐guided transthoracic needle biopsy in lung cancer harboring epithelial growth factor receptor mutation: A case report
Systemic air embolism developed after CT ‐guided TTNB, leading to ST‐elevation, myocardial infarction and acute ischemic stroke. The patient recovered completely without sequelae and was diagnosed with adenocarcinoma harboring activatingEGFR mutation. Treatment with gefitinib showed a response. Air embolism is a rare, fatal complication of computed tomography (CT) ‐guided transthoracic needle biopsy (TTNB) of the lung. Here, we report a patient who developed an air embolism after CT‐guided TTNB, which led to ST‐elevation myocardial infarction and acute cerebral ischemia. The patient recovered completely without c...
Source: Thoracic Cancer - October 1, 2020 Category: Cancer & Oncology Authors: Hyung ‐Joo Oh, Won Gi Jeong, Yongwhan Lim, Sang‐Joon Koh, Sung Min Lee, Min‐Seok Kim, Bo‐Gun Koh, Tae‐Ok Kim, Yoo‐Duk Choi, In‐Jae Oh, Young‐Chul Kim, Cheol‐Kyu Park Tags: CASE REPORT Source Type: research

The anticoagulation dilemma and future treatment avenues in patients with breast cancer and atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmia, with a substantial rise in global incidence and prevalence. Ischemic stroke is a frequent complication of AF, since AF perfectly fulfills Virchow's triad of blood stasis, vascular damage and hypercoagulation, making oral anticoagulation (OAC) obligatory for stroke prevention. Direct oral anticoagulants (DOAC), such as dabigatran, which inhibits thrombin, and apixaban, edoxaban and rivaroxaban, which block the activated coagulation factor X (FXa), have some advantages and are largely replacing coumarin-based OAC.
Source: International Journal of Cardiology - September 30, 2020 Category: Cardiology Authors: Anke C. Fender, Dobromir Dobrev Tags: Editorial Source Type: research

An Agathokakological tale of ∆9 -THC: Exploration of Possible Biological Targets.
Abstract ∆ 9 -Tetrahydrocannabinol (∆9 -THC), the active phytocannabinoid in cannabis, is virtually an adjunct to the endogenous endocannabinoid signaling system. By interacting with G-protein-coupled receptors CB1 and CB2, ∆9 -THC affects peripheral and central circulation by lowering sympathetic activity, altering gene expression, cell proliferation, and differentiation, decreasing leukocyte migration, modulating neurotransmitter release thereby modulating cardiovascular functioning, tumorigenesis, immune responses, behavioral and locomotory activities respectively. ∆ 9 -THC is effective in suppressing c...
Source: Current Drug Targets - September 30, 2020 Category: Drugs & Pharmacology Authors: Mathew B, Harilal S, Musa A, Kumar R, Parambi DGT, Jose J, Uddin MS, Shah MA, Behl T, Unnikrishnan MK Tags: Curr Drug Targets Source Type: research

Parental, Perinatal, and Childhood Risk Factors for Development of Irritable Bowel Syndrome: A Systematic Review.
Conclusions: More effort is needed to identify what fetal and maternal factors are associated with low birth weight and IBS. A well-executed prospective birth cohort with a collection of bio-samples and functional data will provide a better understanding of how adversity and the interplay between genetics, epigenetics, and numerous risk factors affect the development of IBS. PMID: 32989183 [PubMed]
Source: Journal of Neurogastroenterology and Motility - September 30, 2020 Category: Gastroenterology Tags: J Neurogastroenterol Motil Source Type: research

A Multicenter Prospective Observational Cohort Study to Investigate the Effectiveness and Safety of Rivaroxaban in Japanese Venous Thromboembolism Patients (The J'xactly Study).
CONCLUSIONS: In Japanese clinical practice, a single-drug approach with rivaroxaban was demonstrated to be a valuable treatment for a broad range of VTE patients. PMID: 32981924 [PubMed - as supplied by publisher]
Source: Circulation Journal - September 25, 2020 Category: Cardiology Authors: Okumura Y, Fukuda I, Nakamura M, Yamada N, Takayama M, Maeda H, Yamashita T, Ikeda T, Mo M, Kobayashi T, Niwa A, Matsuo H, Yokoi H, Koga M, Yamazaki T, Hirayama A, J’xactly Investigators Tags: Circ J Source Type: research

Higher cardiovascular mortality in men with persistent dipstick hematuria
ConclusionsIn men, persistent dipstick hematuria is a significantly risk factor of all-cause mortality, in particular cardiovascular death among general screening participants.
Source: Clinical and Experimental Nephrology - September 21, 2020 Category: Urology & Nephrology Source Type: research

Making sense of diabetes
(University of Missouri-Columbia) Throughout her 38-year nursing career, Laurel Despins has progressed from a bedside nurse to a clinical nurse specialist and has worked in medical, surgical and cardiac intensive care units. She noticed diabetes is rarely referred to as a primary cause of death in itself, yet the disease is a leading contributor to deaths involving heart disease, stroke and cancer.
Source: EurekAlert! - Cancer - September 21, 2020 Category: Cancer & Oncology Source Type: news

Impact of the preoperative body mass index on the postoperative outcomes in patients with completely resected non-small cell lung cancer: A retrospective analysis of 16,503 cases in a Japanese Lung Cancer Registry Study
Obesity is responsible for multiple chronic diseases, including type 2 diabetes, hypertension, coronary artery disease, stroke, and several types of cancer [1]. The body mass index (BMI) —as an easy-to obtain, acceptable proxy for thinness and fatness—has been found to be associated with health risk and death in many populations. According to the World Health Organization definition, the normal range of BMI is defined as 18.5 to
Source: Lung Cancer - September 18, 2020 Category: Cancer & Oncology Authors: Koichi Fukumoto, Shoichi Mori, Yasushi Shintani, Jiro Okami, Hiroyuki Ito, Takashi Ohtsuka, Shinichi Toyooka, Takeshi Mori, Shun-ichi Watanabe, Hisao Asamura, Masayuki Chida, Hiroshi Date, Shunsuke Endo, Takeshi Nagayasu, Ryoichi Nakanishi, Etsuo Miyaoka, Source Type: research

Monoclonal antibody as an emerging therapy for acute ischemic stroke.
Authors: Woods D, Jiang Q, Chu XP Abstract Acute ischemic stroke (AIS) is the 5th leading cause of death and the leading cause of neurological disability in the United States. The oxygen and glucose deprivation associated with AIS not only leads to neuronal cell death, but also increases the inflammatory response, therefore decreasing the functional outcome of the brain. The only pharmacological intervention approved by the US Federal Food and Drug Administration for treatment of AIS is tissue plasminogen activator (t-PA), however, such treatment can only be given within 4.5 hours of the onset of stroke-like sympto...
Source: International Journal of Physiology, Pathophysiology and Pharmacology - September 18, 2020 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research

Pathophysiology, Mechanism, and Outcome of Ischemic Stroke in Cancer Patients
The purpose of this study is to assess the risk factors, biomarkers of stroke, mechanism, and outcomes of cerebral infarction among cancerous diseases.
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2020 Category: Neurology Authors: Mohamed Abdelsalam, Mohammad Abu-Hegazy, Hend Ahmed El-Hadaad, Hanan Wahba, Hossam Egila, Ahmed Esmael Source Type: research

Perlecan, a Modular Instructive Proteoglycan with Diverse Functional Properties.
This study reviewed some new aspects of the modular proteoglycan perlecan, a colossal proteoglycan with a 467 kDa core protein and five distinct functional domains. Perlecan is a heparan sulphate proteoglycan that transiently displays native CS sulphation motifs 4-C-3 and 7-D-4 during tissue morphogenesis these are expressed by progenitor cell populations during tissue development. Perlecan is susceptible to fragmentation by proteases during tissue development and in pathological tissues particularly in domains IV and V. The fragmentation pattern of domain IV has been suggested as a means of grading prostate cancer. Doma...
Source: The International Journal of Biochemistry and Cell Biology - September 14, 2020 Category: Biochemistry Authors: Melrose J Tags: Int J Biochem Cell Biol Source Type: research

Efficacy and safety of intravenous thrombolysis for acute ischemic stroke in cancer patients: a systemic review and meta-analysis.
Authors: Huang S, Lu X, Tang LV, Hu Y Abstract The efficacy and safety of intravenous thrombolysis (IVT) for acute ischemic stroke (AIS) in cancer patients remained uncertain due to low level evidence in the latest guideline for AIS. The aim of this study was to assess the efficacy and safety of IVT in cancer patients with stronger evidence. We searched Medline, Embase, CENTRAL and ClinicalTrials.gov until April 2020 for studies reporting outcomes of functional independence, hemorrhagic transformation (HT), symptomatic intracranial hemorrhage (SICH), major bleeding (MB), in-hospital mortality or 3-month mortality a...
Source: American Journal of Translational Research - September 13, 2020 Category: Research Tags: Am J Transl Res Source Type: research

Direct oral anticoagulants in the prevention of stroke in breast cancer patients with atrial fibrillation during adjuvant endocrine therapy: A cohort study
Atrial fibrillation (AF) is a frequent comorbidity in malignant patients. Anticancer therapies complicate anticoagulant strategy. We evaluated the safety and efficacy of long-term use of direct oral anticoagulants (DOACs) in breast cancer women.
Source: International Journal of Cardiology - September 11, 2020 Category: Cardiology Authors: Renata Pacholczak-Madej, Stanis ława Bazan-Socha, Lech Zaręba, Anetta Undas, Jerzy Dropiński Source Type: research

CT radiomics predicts esophageal cancer outcomes
Machine-learning models that assess both peritumoral and intratumoral radiomics...Read more on AuntMinnie.comRelated Reading: PET radiomics tailor head/neck cancer treatment CT radiomics can predict COVID-19 pneumonia outcomes AI, radiomics can predict stroke treatment success Can radiomics improve CT lung cancer screening? AI can predict if COVID-19 patients will need ventilators
Source: AuntMinnie.com Headlines - September 11, 2020 Category: Radiology Source Type: news

FDA Clears New Neurosurgical Port for Deep Brain Access FDA Clears New Neurosurgical Port for Deep Brain Access
The FDA has cleared MindsEye (Minnetronix Medical), the first minimally invasive, expandable and retractable port that allows deep brain access to treat stroke, cancer, and other conditionsFDA Approvals
Source: Medscape Hematology-Oncology Headlines - September 11, 2020 Category: Cancer & Oncology Tags: Neurology & Neurosurgery News Alert Source Type: news

On-the-job exposure to high levels of pesticide increases heart disease and stroke risk
(Natural News) Scientists have known for a long time that pesticides are harmful to human health. Previous research links pesticide exposure to cancer, respiratory problems and birth defects. A recent study is one of the latest to probe the toxic effects of pesticide exposure. Researchers from the University of Hawai?i at M?noa looked at middle-aged men of...
Source: NaturalNews.com - September 10, 2020 Category: Consumer Health News Source Type: news

Recent advances in fluorescent probes for extracellular pH detection and imaging.
Abstract Extracellular pH plays vital roles in physiological and pathological processes including tumor metastasis and chemotherapy resistance. Abnormal extracellular pH is known to be associated with various pathological states, such as those in tumors, ischemic stroke, infection, and inflammation. Specifically, dysregulated pH is regarded as a hallmark of cancer because enhanced glycolysis and poor perfusion in most solid malignant tumors create an acidic extracellular environment, which enhances tumor growth, invasion, and metastasis. Close connection between the cell functions with extracellular pH means that ...
Source: Analytical Biochemistry - September 10, 2020 Category: Biochemistry Authors: Chen Y Tags: Anal Biochem Source Type: research

Occult cancer diagnosed following acute ischemic stroke.
Authors: Rioux B, Keezer MR, Gioia LC PMID: 32900764 [PubMed - in process]
Source: Canadian Medical Association Journal - September 10, 2020 Category: General Medicine Tags: CMAJ Source Type: research

Nationwide Patterns of Hemorrhagic Stroke among Patients Hospitalized with Brain Metastases: Influence of Primary Cancer Diagnosis and Anticoagulation
Brain metastases can contribute to a decreased quality of life for patients with cancer, often leading to malaise, neurologic dysfunction, or death. Intracerebral hemorrhage (ICH) is especially feared complication in patients with brain metastases given the potential for significant morbidity and mortality.
Source: International Journal of Radiation Oncology * Biology * Physics - September 10, 2020 Category: Radiology Authors: Henry Park, Victor Lee, Vikram Jairam, James Yu Source Type: research

Height Is Associated with Dyslipidemia in Korean Premenopausal Women: Data from the Korea National Health and Nutrition Examination Survey
Conclusion: There was a dose-dependent correlation between adult height and adverse lipid profile in premenopausal Korean women who did not have CVD. This finding could serve as further evidence that dyslipidemia can be a link between shortness and CVD.Cardiology
Source: Cardiology - September 10, 2020 Category: Cardiology Source Type: research

Featured Reviews: Behavioural activation therapy for depression
How well does behavioural activation therapy work for depression in adults?  And what about the effects of this treatment on depression for adults with long‐term physical conditions? Two new Cochrane systematic reviews look at the available evidence.Depression is a common mental health problem. It can cause a persistent feeling of sadness and loss of interest in people, activities, and things that were once enjoyable. Treatments for depression include psychological therapies (talking therapies). Two reviews recently published byCochrane Common Mental Disordersfocus on a type of psychological therapy called behavioural a...
Source: Cochrane News and Events - September 9, 2020 Category: Information Technology Authors: Muriah Umoquit Source Type: news

Multimorbidity in Patients With Acute Coronary Syndrome Is Associated With Greater Mortality, Higher Readmission Rates, and Increased Length of Stay: A Systematic Review.
CONCLUSIONS: Multimorbid patients with ACS are at a greater risk for worse outcomes than their nonmultimorbid counterparts. Lack of consistent measurement makes interpretation of the impact of multimorbidity challenging and emphasizes the need for more research on multimorbidity's effects on postdischarge healthcare utilization. PMID: 32925234 [PubMed - as supplied by publisher]
Source: The Journal of Cardiovascular Nursing - September 8, 2020 Category: Nursing Authors: Breen K, Finnegan L, Vuckovic K, Fink A, Rosamond W, DeVon HA Tags: J Cardiovasc Nurs Source Type: research

Healthcare fragmentation and cardiovascular risk control among older cancer survivors in the Reasons for Geographic And Racial Differences in Stroke (REGARDS) study
ConclusionsMore fragmented care was associated with worse glycemic control among cancer survivors with diabetes who reported excellent, very good, or good health. Associations were not observed for control of hypertension or hyperlipidemia.Implications for Cancer SurvivorsReducing fragmentation may support glucose control among survivors with diabetes.
Source: Journal of Cancer Survivorship - September 7, 2020 Category: Cancer & Oncology Source Type: research

Featured Review: Taxation of the fat content of foods for reducing their consumption and preventing obesity or other adverse health outcomes
ConclusionsWe did not find enough reliable evidence to find out whether a tax on the fat content of foods resulted in people eating less fat, or less saturated fat.We did not find any evidence about how a tax on the fat content of foods affected obesity or overweight.The results of our review will change when further evidence becomes available.Discussing the findings of this review, lead author Stefan Lhachimi said, “A tax on saturated fats could be in principle a good approach to reduce the consumption of so-called junk foods, a group of food products which is fiendishly tricky to define in legal terms. By taxing a main...
Source: Cochrane News and Events - September 7, 2020 Category: Information Technology Authors: Rachel Klabunde Source Type: news

Applying Ethical Principles When Discussing Alcohol Use During Pregnancy
AbstractOver the past 2 decades, more women in the United States are engaging in excessive alcohol use, including women of reproductive age. Consuming alcohol in amounts greater than recommended limits is associated with an increased risk for adverse health effects, such as breast cancer, hypertension stroke, spontaneous abortion, and infertility. Any amount of alcohol use during pregnancy can result in a fetal alcohol spectrum disorder. No safe time, safe amount, or safe type of alcohol to consume during pregnancy has been identified. Contradictory beliefs about alcohol use, fear of stigmatization, and potential legal con...
Source: Journal of Midwifery and Women's Health - September 6, 2020 Category: Midwifery Authors: Alexandra Edwards, Beth Kelsey, Marilyn Pierce ‐Bulger, Susan Rawlins, Catherine Ruhl, Sharon Ryan, Diane K. King Tags: Innovations from the Field Source Type: research

The Lancet: Many countries falling behind on global commitments to tackling premature deaths from chronic diseases, such as diabetes, lung cancer and heart disease
(The Lancet) Around the world, the risk of dying prematurely from preventable and largely treatable chronic diseases such as stroke, heart disease, and stomach cancer has declined steadily over the past decade, but death rates from other chronic diseases such as diabetes, lung cancer, colon cancer, and liver cancer are declining too slowly or worsening in many countries.
Source: EurekAlert! - Social and Behavioral Science - September 3, 2020 Category: International Medicine & Public Health Source Type: news

Clinical Features of Trousseau Syndrome With Cerebral Infarction as the Initial Manifestation
Conclusions: Trousseau syndrome with cerebral infarction as the initial manifestation was associated with metastatic cancer and depressive state. There was no difference in coagulation status between the 2 groups.
Source: The Neurologist - September 1, 2020 Category: Neurology Tags: Original Articles Source Type: research

Occult lung cancer manifesting within the first year after stroke
Lung cancer and stroke share smoking as a major cause of disease. We investigated prevalence and risk of occult lung cancer with manifestation during the first year after stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 15, 2020 Category: Neurology Authors: Alejandro Daniel Babore, Anne Julie Tybjerg, Klaus Kaae Andersen, Tom Skyhoj Olsen Source Type: research

Clinical Characteristics and Analysis of Lung Cancer- Associated Acute Ischemic Stroke
The incidence of lung cancer and acute ischemic stroke remains high in recent years, both of which occur mostly in people over 60 years old. In the present study, we aimed to further clarify the pathogenesis of lung cancer-associated acute ischemic stroke (LCA-AIS) by comparing and analyzing clinical characteristics of stroke patients with or without lung cancer.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Jing Zhang, Jingxia Zhao Source Type: research

Association of Cancer Cell Type and Extracellular Vesicles With Coagulopathy in Patients With Lung Cancer and Stroke Brief Report
Conclusions—Our findings indicate that cancer cell type is associated with circulating EV levels and coagulopathy in patients with lung cancer and stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Jong-Won Chung, Yeon Hee Cho, Myung-Ju Ahn, Mi Ji Lee, Gyeong-Moon Kim, Chin-Sang Chung, Oh Young Bang Tags: Biomarkers, Mechanisms, Translational Studies, Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research

Substitution of Linoleic Acid for Other Macronutrients and the Risk of Ischemic Stroke Clinical Sciences
Conclusions—This study suggests that replacing saturated fatty acid, glycemic carbohydrate, or monounsaturated fatty acid with linoleic acid may be associated with a lower risk of ischemic stroke.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Stine K. Veno, Erik B. Schmidt, Marianne U. Jakobsen, Soren Lundbye–Christensen, Flemming W. Bach, Kim Overvad Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Whole Grain Consumption and Risk of Ischemic Stroke Clinical Sciences
Conclusions—Although overall consumption of whole grains was not associated with lower risk of ischemic stroke, greater consumption of whole grain cold breakfast cereal and bran was significantly associated with a lower risk of ischemic stroke. More studies are needed to replicate these associations between individual whole grain foods and risk of ischemic stroke among other populations.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Juan Juan, Gang Liu, Walter C. Willett, Frank B. Hu, Kathryn M. Rexrode, Qi Sun Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Eosinophil Cationic Protein, Carotid Plaque, and Incidence of Stroke Clinical Sciences
Conclusions—High ECP is associated with increased incidence of IS. The association between ECP and IS was also present in the subgroup with carotid plaque.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Johannes Sundstrom, Martin Soderholm, Yan Borne, Jan Nilsson, Margaretha Persson, Gerd Ostling, Olle Melander, Marȷu Orho–Melander, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Adherence to a Healthy Nordic Diet and Risk of Stroke Clinical Sciences
Conclusions—Our findings suggest that a healthy Nordic diet may be recommended for the prevention of stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Camilla Plambeck Hansen, Kim Overvad, Cecilie Kyro, Anȷa Olsen, Anne Tȷonneland, Soren Paaske Johnsen, Marianne Uhre Jakobsen, Christina Catherine Dahm Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Orosomucoid, Carotid Plaque, and Incidence of Stroke Clinical Sciences
Conclusions— Elevated levels of orosomucoid are associated with increased occurrence of carotid plaque and increased incidence of ischemic stroke. The combination of high orosomucoid and carotid plaque substantially increase the risk of stroke.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Berntsson, J., Ostling, G., Persson, M., Smith, J. G., Hedblad, B., Engstrom, G. Tags: Cardiovascular Disease, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Cancer in Young Adults With Ischemic Stroke Clinical Sciences
Conclusions— Cancer, and especially active cancer and no other apparent cause for stroke, is associated with unfavorable survival among young stroke patients.
Source: Stroke - May 22, 2015 Category: Neurology Authors: Aarnio, K., Joensuu, H., Haapaniemi, E., Melkas, S., Kaste, M., Tatlisumak, T., Putaala, J. Tags: Acute Cerebral Infarction, Risk Factors for Stroke, Stroke in Children and the Young Clinical Sciences Source Type: research

In-Hospital Stroke Recurrence and Stroke After Transient Ischemic Attack: Frequency and Risk Factors Clinical Sciences
Conclusions— In-hospital stroke recurrence was low with optimal current management. Patients with a history of TIA, severe symptomatic carotid stenosis, or uncommon causes of stroke were at higher risk. Pneumonia was associated with a higher risk of stroke recurrence in patients with initial TIA or minor stroke but not in the overall population studied. Aphasia may bias the detection rate by concealing new neurological symptoms.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Erdur, H., Scheitz, J. F., Ebinger, M., Rocco, A., Grittner, U., Meisel, A., Rothwell, P. M., Endres, M., Nolte, C. H. Tags: Acute Cerebral Infarction, Carotid Stenosis, Emergency treatment of Stroke, Antiplatelets Clinical Sciences Source Type: research

Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke Clinical Sciences
Conclusions— An AF-GRS can identify 20% of individuals who are at 2-fold increased risk for incident AF and at 23% increased risk for ischemic stroke. Targeting diagnostic or therapeutic interventions to this subset may prove clinically useful.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Tada, H., Shiffman, D., Smith, J. G., Sjogren, M., Lubitz, S. A., Ellinor, P. T., Louie, J. Z., Catanese, J. J., Engstrom, G., Devlin, J. J., Kathiresan, S., Melander, O. Tags: Genetics of Stroke Clinical Sciences Source Type: research

Cryptogenic Subtype Predicts Reduced Survival Among Cancer Patients With Ischemic Stroke Clinical Sciences
Conclusions— Cryptogenic stroke is independently associated with reduced survival in patients with active cancer and ischemic stroke.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Navi, B. B., Singer, S., Merkler, A. E., Cheng, N. T., Stone, J. B., Kamel, H., Iadecola, C., Elkind, M. S. V., DeAngelis, L. M. Tags: Arterial thrombosis, Thrombophilia, Acute Cerebral Infarction, Embolic stroke, Pathology of Stroke Clinical Sciences Source Type: research

Primary Preventive Potential for Stroke by Avoidance of Major Lifestyle Risk Factors: The European Prospective Investigation Into Cancer and Nutrition-Heidelberg Cohort Clinical Sciences
Conclusions— Our analysis confirms the strong primary prevention potential for stroke based on avoidance of excess body weight, smoking, heavy alcohol consumption, unhealthy diet, and physical inactivity.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Tikk, K., Sookthai, D., Monni, S., Gross, M.-L., Lichy, C., Kloss, M., Kaaks, R. Tags: Primary and Secondary Stroke Prevention, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research