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Healthy People Shouldn ’ t Take Daily Aspirin To Prevent Heart Disease, Review Finds
(CNN) — Still taking a daily aspirin to ward off heart attacks? You might want to think again, according to a new review. Aspirin is still one of the most commonly used medications in the world, even though it’s no longer recommended as a preventative by many health authorities. There is no evidence that low-dose aspirin — less than 325 milligrams a day — should be taken by most adults in good cardiovascular health, according to a new review of existing research that published Wednesday in the British Journal of Clinical Pharmacology. The review, which focused on the risks and benefits of low-dose daily asp...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 3, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News aspirin CNN Source Type: news

Consider the Promises and Challenges of Medical Image Analyses Using Machine Learning
Medical imaging saves millions of lives each year, helping doctors detect and diagnose a wide range of diseases, from cancer and appendicitis to stroke and heart disease. Because non-invasive early disease detection saves so many lives, scientific investment continues to increase. Artifical intelligence (AI) has the potential to revolutionize the medical imaging industry by sifting through mountains of scans quickly and offering providers and patients with life-changing insights into a variety of diseases, injuries, and conditions that may be hard to detect without the supplemental technology. Images are the largest source...
Source: MDDI - June 2, 2020 Category: Medical Devices Authors: Partha S. Anbil and Michael T. Ricci Tags: Imaging Source Type: news

Prostate Cancer Drug Could Be 'Game Changing'
For men with advanced prostate cancer, a new hormone therapy pill works better than standard injections -- and carries a much lower risk of heart attack or stroke.
Source: WebMD Health - May 30, 2020 Category: Consumer Health News Source Type: news

The Women's Health Initiative Estrogen-alone Trial had differential disease and medical expenditure consequences across age groups
Conclusion: The decline in ET utilization had differential disease and expenditure consequences by age groups in the United States. These results are limited by the lack of inclusion of vasomotor symptom benefit and costs of alternative medications for these symptoms in the analysis.
Source: Menopause - May 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Prostate Cancer Drug Could Be ' Game Changing, ' Researchers Say
FRIDAY, May 29, 2020 -- For men with advanced prostate cancer, a new hormone therapy pill works better than standard injections -- and carries a much lower risk of heart attack or stroke, a clinical trial has found. The drug, called relugolix, is...
Source: Drugs.com - Daily MedNews - May 29, 2020 Category: General Medicine Source Type: news

Double-contrast technique could boost MRI for cancer
A new double-contrast MRI technique in development could help the modality...Read more on AuntMinnie.comRelated Reading: COVID-19 neuro findings marked by mental status, stroke fMRI-based machine learning helps predict coma outcomes ISMRM annual meeting goes virtual MRI illuminates neurologic manifestations of COVID-19 MRI could help predict efficacy of stem cell therapy
Source: AuntMinnie.com Headlines - May 28, 2020 Category: Radiology Source Type: news

Modified-BEP Chemotherapy in Patients With Germ-Cell Tumors Treated at a Comprehensive Cancer Center
Conclusion: In GCT patients, our mBEP-schedule would suggest an effective treatment modality without suffering meaningful pulmonary toxicity.
Source: American Journal of Clinical Oncology - May 27, 2020 Category: Cancer & Oncology Tags: Original Articles: Genitourinary Source Type: research

Survival in Adversity: Trends in Mortality Among Blacks in the United States, 1900-2010.
Authors: Hahn RA Abstract The goal of this study was to analyze trends in black age-adjusted mortality rates (AADR) from 1900 through 2010 and to propose explanations. Analyses included a descriptive study of trends in AADR from major causes for blacks and age-specific all-cause mortality at each decade. In 1900, all-cause AADRs were higher for blacks than whites. Over the century, differences decreased substantially. Reductions mortality were greatest among young people, lowest among older adults. Deaths from infectious diseases showed the greatest decrease. Heart disease mortality among blacks increased from 1920...
Source: International Journal of Health Services - May 26, 2020 Category: Health Management Tags: Int J Health Serv Source Type: research

Prevalence of Dysphagia in China: An Epidemiological Survey of 5943 Participants
ConclusionDysphagia is prevalent in China among older individuals and people who have suffered a stroke, HNCs, or NDDs. The prevalence of dysphagia increases steadily with increasing age and presence of comorbid disease. People with dysphagia are more likely to suffer from malnutrition.
Source: Dysphagia - May 26, 2020 Category: Speech-Language Pathology Source Type: research

Cardiac Transplantation for Cancer Involving the Heart
Cardiac Cancer (CC) that arises from or involves the heart can present as heart failure, chest pain, stroke or another thromboembolic event. Although patients with CC have limited treatment options, in other organ cancers such as hepatocellular carcinoma, liver transplant improves 5-year overall survival in carefully selected patients1. For CC, however, the benefit of replacing the cancerous heart is uncertain because one-year survival is generally estimated around 50% after this rare operation.
Source: The Journal of Heart and Lung Transplantation - May 24, 2020 Category: Transplant Surgery Authors: Matthew Wingo, Andreas R. de Biasi, Yasuhiro Shudo, Vijaya Bharathi, Anthony Blackburn, Mario Gaudino, Leonard N. Girardi, Y. Joseph Woo Tags: Research Correspondence Source Type: research

Coronary artery calcification scoring system based on the coronary artery calcium data and reporting system (CAC-DRS) predicts major adverse cardiovascular events or all-cause death in patients with potentially curable lung cancer without a history of cardiovascular disease
In conclusion, the CAC-DRS score on non-gated standard CT can predict incident MACEs and/or all-cause death in patients with potentially curable resected lung cancer. Lung cancer survivors with a greater CAC-DRS category may need more active management of cardiovascular risk factors.
Source: Heart and Vessels - May 22, 2020 Category: Cardiology Source Type: research

WHRY funds studies on stroke, endometrial cancer, and addiction to opioids
Women ’s Health Research at Yale is expanding its work to “address the enduring and pressing medical conditions that continue to affect women’s lives.”
Source: Yale Science and Health News - May 21, 2020 Category: Universities & Medical Training Source Type: news

Adults at high-risk of severe coronavirus disease-2019 (Covid-19) in Brazil
CONCLUSIONS Proportion and total number of adults at risk of severe Covid-19 are high in Brazil, with wide variation across states and adult subgroups. T hese findings should be considered while designing and implementing prevention measures in Brazil. We argue that these results support broad social isolation measures, particularly when testing capacity for SARS-CoV-2 is limited.
Source: Revista de Saude Publica - May 21, 2020 Category: International Medicine & Public Health Source Type: research

The Association Between Nonalcoholic Fatty Liver Disease and Risk of Cardiovascular Disease, Stroke, and Extra-Hepatic Cancers
Publication date: Available online 20 May 2020Source: Journal of Clinical and Experimental HepatologyAuthor(s): Nicolette Veracruz, Bilal Hameed, Sammy Saab, Robert J. Wong
Source: Journal of Clinical and Experimental Hepatology - May 20, 2020 Category: Gastroenterology Source Type: research

Association of nut intake with risk factors, cardiovascular disease, and mortality in 16 countries from 5 continents: analysis from the Prospective Urban and Rural Epidemiology (PURE) study.
CONCLUSIONS: Higher nut intake was associated with lower mortality risk from both cardiovascular and noncardiovascular causes in low-, middle-, and high-income countries. PMID: 32433740 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - May 20, 2020 Category: Nutrition Authors: de Souza RJ, Dehghan M, Mente A, Bangdiwala SI, Ahmed SH, Alhabib KF, Altuntas Y, Basiak-Rasała A, Dagenais GR, Diaz R, Amma LI, Kelishadi R, Khatib R, Lear SA, Lopez-Jaramillo P, Mohan V, Poirier P, Rangarajan S, Rosengren A, Ismail R, Swaminathan S, We Tags: Am J Clin Nutr Source Type: research

Cancers, Vol. 12, Pages 1285: Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children
Conclusion: This represents the largest GWAS meta-analysis conducted to date associating SNPs to VTE in children and adolescents treated on childhood ALL protocols. Validation of these findings is needed and may then lead to patient stratification for VTE preventive interventions. As VTE hemostasis involves multiple pathways, a more powerful GWAS is needed to detect combination of variants associated with VTE.
Source: Cancers - May 19, 2020 Category: Cancer & Oncology Authors: Marion K. Mateos Morten Tulstrup Michael CJ Quinn Ruta Tuckuviene Glenn M. Marshall Ramneek Gupta Chelsea Mayoh Benjamin O. Wolthers Pasquale M. Barbaro Ellen Ruud Rosemary Sutton Pasi Huttunen Tamas Revesz Sonata S. Trakymiene Draga Barbaric Ulf Tedg år Tags: Article Source Type: research

Reduction in saturated fat intake for cardiovascular disease.
CONCLUSIONS: The findings of this updated review suggest that reducing saturated fat intake for at least two years causes a potentially important reduction in combined cardiovascular events. Replacing the energy from saturated fat with polyunsaturated fat or carbohydrate appear to be useful strategies, while effects of replacement with monounsaturated fat are unclear. The reduction in combined cardiovascular events resulting from reducing saturated fat did not alter by study duration, sex or baseline level of cardiovascular risk, but greater reduction in saturated fat caused greater reductions in cardiovascular events. ...
Source: Cochrane Database of Systematic Reviews - May 19, 2020 Category: General Medicine Authors: Hooper L, Martin N, Jimoh OF, Kirk C, Foster E, Abdelhamid AS Tags: Cochrane Database Syst Rev Source Type: research

Explaining Health Outcomes of Asian Immigrants: Does Ethnicity Matter?
AbstractThe present study intended to evaluate whether 4 discrete ethnic groups of Asian immigrants could, for empirical reasons, be assigned a set of unique operating factors explaining health outcomes of members. The set comprised several acculturation, social structure, lifestyle, and health-related factors. Our study asked if these factorsuniformly explained health outcomes across the 4 groups. We pooled National Health Interview Survey (NHIS) data dating 1999 –2015 and developed 2 outcomes: self-rated health and self-reported chronic illness (specifically, diagnosis of cardiovascular disease, prediabetes/diabetes, h...
Source: Journal of Racial and Ethnic Health Disparities - May 16, 2020 Category: International Medicine & Public Health Source Type: research

Low Serum Eicosapentaenoic Acid Levels in Cryptogenic Stroke with Active Cancer
Since Armand Trousseau first described migratory superficial thrombophlebitis in 1865, patients with malignant cancer have been known to be in a hypercoagulable state and at risk for the development of cancer-associated thrombosis.1 Approximately 7% of cancer patients have symptomatic cerebrovascular diseases during the clinical course of cancer, and 15% have cerebrovascular lesions at autopsy.2 Previous studies have demonstrated that cancer patients with cryptogenic ischemic stroke often have high serum D-dimer levels and multiple vascular lesions and show cryptogenic stroke etiology, which seems to be due to a hypercoagulable state.
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2020 Category: Neurology Authors: Tesseki Izumi, Hitoki Nanaura, Naohiko Iguchi, Maki Ozaki, Kazuma Sugie Source Type: research

Pilot Study of Quantitative Methods for Differentiating Pharyngeal Swallowing Mechanics by Dysphagia Etiology
This study demonstrated that swallowing mechanics among cohorts of dysphagic patients can be differentiated using kinematics and CASM, providing different but complementary quantitative methods for investigating the impact of various disease states on swallowing function.
Source: Dysphagia - May 14, 2020 Category: Speech-Language Pathology Source Type: research

Age at death in elderly cohorts of four European countries of the Seven Countries Study: the role of comorbidities.
CONCLUSION: AD seems a valuable indicator of all-cause mortality when the study population has reached or approached the extinction. PMID: 32410168 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - May 14, 2020 Category: Geriatrics Authors: Menotti A, Puddu PE, Tolonen H Tags: Aging Clin Exp Res Source Type: research

Genetic susceptibility, plant-based dietary patterns, and risk of cardiovascular disease.
CONCLUSION: Adherence to healthy plant-based diets may be associated with a decreased incidence of CVD in the entire population, suggesting that plant-based dietary patterns may modify the risk of CVD, regardless of genetic susceptibility. PMID: 32401300 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - May 13, 2020 Category: Nutrition Authors: Heianza Y, Zhou T, Sun D, Hu FB, Manson JE, Qi L Tags: Am J Clin Nutr Source Type: research

Goal-directed therapy with bolus albumin 5% is not superior to bolus ringer acetate in maintaining systemic and mesenteric oxygen delivery in major upper abdominal surgery: A randomised controlled trial
CONCLUSION Bolus human albumin 5% was not superior to bolus ringer acetate in maintaining systemic or mesenteric oxygen delivery in elective major upper gastrointestinal cancer surgery, despite the administration of larger volumes of trial fluid in the ringer acetate group. No significant difference was seen in fluid-related complications or LOS. TRIAL REGISTRATION https://eudract.ema.europa.eu/ Identifier: 2013-002217-36.
Source: European Journal of Anaesthesiology - May 11, 2020 Category: Anesthesiology Tags: Haemodynamics Source Type: research

Weight Change and Mortality from Cardiovascular Diseases: The Japan Collaborative Cohort Study.
CONCLUSIONS: Weight loss or gain could be a risk factor for mortality from total or ischemic CVD, while weight loss could be a risk factor for intracerebral hemorrhage. PMID: 32378530 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - May 8, 2020 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Is Arterial Stiffness a Determinant of Hypotension?
ConclusionsHypotension is a quite common phenomenon in older subjects. Its prevention requires a more accurate management of hypertension aimed at better identifying which older subjects in whom intensive BP control may be harmful and those who may benefit from it.
Source: High Blood Pressure and Cardiovascular Prevention - May 8, 2020 Category: Cardiology Source Type: research

Longitudinal atherosclerotic changes after radio(chemo)therapy of hypopharyngeal carcinoma
This study aimed at a closer characterization of this damage and its development in time with a longitudi...
Source: Radiation Oncology - May 7, 2020 Category: Cancer & Oncology Authors: Cristoforo Simonetto, Michael Mayinger, Thamer Ahmed, Kai Borm, Pavel Kundr át, Steffi Pigorsch, Jan Christian Kaiser and Stephanie E. Combs Tags: Research Source Type: research

Overlooked Virus Killer
Sales of vitamin C supplements have tripled in the last few weeks… And the most powerful kind of vitamin C is sold out on Amazon. (More on that in a minute.) I’m glad to see people turning to vitamin C. But the the chewable form you usually find at the drugstore won’t give you the boost you’re looking for. You see, absorption — or bioavailability — is an issue, and your body can only absorb about 500 mg of this conventional form of vitamin C before you hit saturation. And that’s nowhere near enough. In a moment I’ll show you a better form of vitamin C… and how you can take ...
Source: Al Sears, MD Natural Remedies - May 6, 2020 Category: Complementary Medicine Authors: Dr.A.Sears Tags: Health Nutrition Source Type: news

MicroRNA-126: Dual Role in Angiogenesis Dependent Diseases.
CONCLUSION: MicroRNA-126 can bind to multiple targets and potentially be both positive and negative regulators of gene expression. Thus, microRNA-126 could cause the opposite biological effects depending on the context. As a result, understanding the different cellular pathways that microRNA-126 regulate angiogenesis through them in various situations is a critical aspect in the development of novel and effective treatments for diseases with insufficient angiogenesis. So it is critical to understand its role in governing angiogenesis during pathological and even physiological conditions. PMID: 32364067 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - May 4, 2020 Category: Drugs & Pharmacology Authors: Nammian P, Razban V, Tabei SMB, Asadi-Yousefabad SL Tags: Curr Pharm Des Source Type: research

Lead Anti-obesity Compounds from Nature.
Conclusion-Consumption of diets comprising high amounts of active anti-obesity natural compounds is a promising strategy for the suppression of lipid accumulation and adipogenesis in obese individuals. PMID: 32364084 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - May 3, 2020 Category: Endocrinology Authors: Dahiya V, Vasudeva N, Sharma S, Kumar A, Rowley D Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

Evidence Base of Clinical Studies on Qi Gong: A Bibliometric Analysis.
CONCLUSIONS: Qigong research publications have been increasing gradually. Reports on study types, participants, Qigong Intervention, and outcomes are diverse and inconsistent. There is an urgent need to develop a set of reporting standards for various interventions of Qigong. Further trials of high methodological quality with sufficient sample size and real world studies are needed to verify the effects of Qigong in health and disease management. PMID: 32444061 [PubMed - as supplied by publisher]
Source: Complementary Therapies in Medicine - May 1, 2020 Category: Complementary Medicine Authors: Zhang YP, Hu RX, Han M, Lai BY, Liang SB, Chen BJ, Robinson N, Chen K, Liu JP Tags: Complement Ther Med Source Type: research

More than a quarter century of the most prescribed sleeping pill: Systematic review of zolpidem use by older adults.
Abstract Zolpidem is widely used to treat insomnia of older adults despite that few randomized controlled studies were conducted in this group. We systematically reviewed the relevant literature on efficacy/effectiveness and safety of zolpidem use by elderly individuals in relevant databases completed with a manual search of key journals. Studies were required to include individuals aged ≥60 years under intervention with zolpidem compared to placebo or other hypnosedatives. Outcomes were either objectively- or subjectively-assessed improvements in specific sleep parameters and safety for clinical use. The 31 r...
Source: Experimental Gerontology - April 30, 2020 Category: Geriatrics Authors: Machado FV, Louzada LL, Cross NE, Camargos EF, Dang-Vu TT, Nóbrega OT Tags: Exp Gerontol Source Type: research

Advancements in the Treatment of Cerebrovascular Complications of Cancer
AbstractPurpose of reviewTo present the new guidelines and therapeutic options regarding cerebrovascular complications of cancer, mainly ischemic stroke, cerebral venous thrombosis (CVT), and leptomeningeal carcinomatosis (LMC).Recent findingsA temporal trend study (2019) revealed that clinicians are still reluctant to apply thrombolysis to cancer patients, although two new studies (2018) reported no increased mortality. Several clinical trials on direct oral anticoagulants (DOACs) showed their superiority or, at least, non-inferiority compared with low molecular weight heparins in the treatment of venous thromboembolism (...
Source: Current Treatment Options in Neurology - April 30, 2020 Category: Neurology Source Type: research

Ability of the number of territories involved on dwi-mri to predict occult systemic malignancy in cryptogenic stroke patients
Lesions in multiple arterial territories is one of the typical features of malignancy patients with cryptogenic stroke. Hence, if patients with cryptogenic stroke display such feature, occult cancer could be predicted. The study aimed to analyze the predictive ability of the number of territories involved on DWI-MRI for occult systemic malignancy (OSM) in patients with cryptogenic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 30, 2020 Category: Neurology Authors: Linjia Guo, Lili Wang, Wenhong Liu Source Type: research

Our Diets Are Changing Because of the Coronavirus Pandemic. Is It for the Better?
The coronavirus pandemic has changed a lot about modern American life: how we work, socialize, and even how we eat. Dining out is a distant memory. But nutritionally, people weren’t exactly thriving in pre-pandemic America. “Before COVID-19 came along, it was increasingly clear that the diet quality and nutritional status of Americans was terrible,” says Dr. Walter Willett, professor of epidemiology and nutrition at Harvard T.H. Chan School of Public Health. More than 40% of U.S. adults are obese. After years of declines, heart disease death rates are on the rise again. So are rates of obesity-linked canc...
Source: TIME: Health - April 28, 2020 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized COVID-19 Source Type: news

Cuba's Role in International Atomic Energy Agency Regional Cooperation in Cardiology.
Authors: Peix A, García B Abstract Cardiovascular diseases are the leading cause of death worldwide, and a health problem in low- and middle-income as well as high-income countries. They also constitute the main cause of death in Latin America, with ischemic heart disease as the principal cause in most countries of the region. In Cuba, heart disease is the first cause of death, followed by cancer and stroke. In its 2030 Agenda for Sustainable Development, the UN recognizes the importance of chronic non-communicable diseases, including cardiovascular diseases. Cuba has participated actively as lead partner in desig...
Source: MEDICC Review - April 28, 2020 Category: International Medicine & Public Health Tags: MEDICC Rev Source Type: research

Cardiotoxicity of Sequential Aromatase Inhibitors Use in Women with Breast Cancer.
Abstract The association between aromatase inhibitors and cardiovascular outcomes is controversial. While some observational studies have assessed their cardiovascular safety as up-front treatments, their cardiotoxic effects as sequential treatments with tamoxifen remains unknown. Thus, we conducted a population-based cohort study using the United Kingdom Clinical Practice Research Datalink linked to the Hospital Episode Statistics and Office for National Statistics databases. A prevalent new-user design was used to propensity score match, in a 1:2 ratio, patients switching from tamoxifen to aromatase inhibitors t...
Source: Am J Epidemiol - April 27, 2020 Category: Epidemiology Authors: Khosrow-Khavar F, Bouganim N, Filion KB, Suissa S, Azoulay L Tags: Am J Epidemiol Source Type: research

Mass. Hospitals Issue PSA: Don ’ t Wait For Treatment Due To Coronavirus Concerns
BOSTON (CBS) – Doctors from Massachusetts hospitals combined to release a series of public service announcements on Thursday urging people who are suffering from serious conditions not to wait for treatment because of coronavirus fears. Doctors said a significant number people with serious ailments are avoiding treatment because they are concerned about being exposed to coronavirus. The series of PSAs will air on Boston television stations starting Thursday. “It’s important that people are cared for when they’re sick, whether that’s for COVID-19 or for something else,” Gov. Charlie Baker said during...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 24, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Featured Health Syndicated CBSN Boston Syndicated Local Cornavirus Coronavirus Gov. Charlie Baker Source Type: news

Archives of Physical Medicine and Rehabilitation Supplements
The American Congress of Rehabilitation Medicine (ACRM) offers an opportunity for members to be the guest editor of a Supplement to its journal, the Archives of Physical Medicine and Rehabilitation (Archives). The goal of the ACRM supplements is to publish high quality scientific manuscripts, which are thematically organized and of interest to ACRM members and to the general readership of the Archives. We are interested in proposals in all fields of rehabilitation, but especially those of interest to the ACRM membership as indicated by the existence of special interest and networking groups for brain injury, spinal cord in...
Source: Archives of Physical Medicine and Rehabilitation - April 21, 2020 Category: Rehabilitation Tags: Organization news Source Type: research

Weight loss since early adulthood, later life risk of fracture hospitalizations, and bone mineral density: a prospective cohort study of 0.5 million Chinese adults
ConclusionsWeight loss from early adulthood to midlife was associated with a higher risk of hip fracture and lower BMD in later life.
Source: Archives of Orthopaedic and Trauma Surgery - April 19, 2020 Category: Orthopaedics Source Type: research

Why strength training may be the best thing you can do for your health
Building muscle reduces the risk of cancer and stroke, boosts brainpower, burns through calories and more – it might even be better for you than cardio
Source: New Scientist - Health - April 15, 2020 Category: Consumer Health News Source Type: research

Deep learning approach for diabetes prediction using PIMA Indian dataset
ConclusionThe outcome of the study confirms that DL provides the best results with the most promising extracted features. DL achieves the accuracy of 98.07% which can be used for further development of the automatic prognosis tool. The accuracy of the DL approach can further be enhanced by including the omics data for prediction of the onset of the disease.
Source: Journal of Diabetes and Metabolic Disorders - April 14, 2020 Category: Endocrinology Source Type: research

Cholesterol: A prelate in cell nucleus and its serendipity. .
Abstract Cholesterol is a chameleon bio-molecule in cellular multiplex. It acts as a prelate in almost every cellular compartment with its site specific characteristics viz. regulation of structural veracity and scaffold fluidity of bio-membranes, insulation of electrical transmission in nerves, controlling of genes by making steroid endocrines, acting as precursors of metabolic regulators and many more with its emerging prophecy in cell nucleus to drive new cell formation. Besides the crucial legacy in cellular functionality, cholesterol is ostracized as a member of LDL particle which has been proved responsible ...
Source: Current Molecular Medicine - April 13, 2020 Category: Molecular Biology Authors: Saxena N, Chandra NC Tags: Curr Mol Med Source Type: research

Co-morbidities in a Retrospective Cohort of Prostate Cancer Patients.
Conclusion: Better chronic disease management is needed among prostate cancer survivors through more effective survivorship care planning and interventions that promote health behaviors. PMID: 32269460 [PubMed - in process]
Source: Ethnicity and Disease - April 11, 2020 Category: International Medicine & Public Health Tags: Ethn Dis Source Type: research

Substitutions between potatoes and other vegetables and risk of ischemic stroke
ConclusionReplacing potatoes with fruiting vegetables was associated with a lower risk of ischemic stroke.
Source: European Journal of Nutrition - April 9, 2020 Category: Nutrition Source Type: research

Malignant melanoma - the most severe skin cancer and neurological pathology.
CONCLUSIONS: Neurological involvement in MM encompasses a myriad of variants and while the clinical setting varies from one patient to another, an underlining neoplasia should be evaluated in suspected patients. PMID: 32239096 [PubMed - in process]
Source: Romanian Journal of Morphology and Embryology - April 5, 2020 Category: General Medicine Tags: Rom J Morphol Embryol Source Type: research

Take Care of Your Heart
February is American Heart Month, and since I am writing this in February, I decided it was time to focus on heart health. Cardiovascular disease (CVD; heart disease and stroke) results in 17.9 million deaths each year and is the leading cause of death globally.1 The number of global deaths is expected to increase to 23.6 million by 2030.1 Of particular interest to our female readers, heart disease kills more women each year than all forms of cancer combined. But nearly 80 percent of cardiac events can be prevented with education and lifestyle changes.
Source: Journal of PeriAnesthesia Nursing - April 1, 2020 Category: Nursing Authors: Jan Odom-Forren Tags: Editorial Opinion Source Type: research

Effects of Laser Acupuncture and Dietary Intervention on Key Obesity Parameters.
Conclusions: Combining laser acupuncture and a dietary intervention has good effects on waist:hip ratio, QoL scores, BMI, and appetite scores in obese patients. PMID: 32351664 [PubMed]
Source: Acupuncture in Medicine - April 1, 2020 Category: Complementary Medicine Authors: Sebayang RG, Aditya C, Abdurrohim K, Lauwrence B, Mihardja H, Kresnawan T, Helianthi DR Tags: Med Acupunct Source Type: research

Risk factors for severe bleeding events during warfarin treatment: the influence of sex, age, comorbidity and co-medication
ConclusionMost of the well-established risk factors were found to be significantly associated with bleeding events in our study. We additionally found that women had a lower incidence of bleeding. Potential biases are selection effects, residual confounding and unmeasured frailty.
Source: European Journal of Clinical Pharmacology - March 28, 2020 Category: Drugs & Pharmacology Source Type: research

Dietary intake of total polyphenols and the risk of all-cause and specific-cause mortality in Japanese adults: the Takayama study
ConclusionsThe results of this prospective study indicate that dietary total polyphenol intake in Japanese is inversely associated with all-cause mortality and mortality from cardiovascular and digestive diseases.
Source: European Journal of Nutrition - March 27, 2020 Category: Nutrition Source Type: research

Dietary patterns generated by the Treelet Transform and risk of stroke: a Danish cohort study.
CONCLUSIONS: The results of this study are broadly in line with current recommendations for a healthy diet to prevent stroke. PMID: 32204745 [PubMed - as supplied by publisher]
Source: Public Health Nutrition - March 24, 2020 Category: International Medicine & Public Health Authors: Frederiksen SB, Themsen HH, Overvad K, Dahm CC Tags: Public Health Nutr Source Type: research