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Total 202604 results found since Jan 2013.

Vasculitis associated with adenosine deaminase 2 deficiency: at the crossroads between Beh çet's disease and autoinflammation. A viewpoint
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1578.ABSTRACTAdenosine deaminase 2 deficiency (DADA2) is a rare monogenic vasculopathy caused by loss-of-function homozygous or compound heterozygous mutations in ADA2, formerly CECR1 (cat eye syndrome chromosome region 1) gene. The DADA2 phenotype is widely heterogeneous, and patients may present with fever, weight loss, livedo reticularis/racemosa, digital ischemia, cutaneous ulceration, peripheral neuropathy, abdominal pain, bowel perforation, and portal or nephrogenic hypertension. More specific manifestations include early-onset ischemic or hemorrhagic stroke...
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: A Colangelo F Tromby G Cafaro R Gerli E Bartoloni C Perricone Source Type: research

Persian version of the Chalder Fatigue Questionnaire and Multidimensional Fatigue Symptom Inventory-Short Form: psychometric properties in Iranian chronic stroke survivors
CONCLUSIONS: The results of this study showed that the CFQ and MFSI-SF have high reliability and validity for chronic stroke survivors.PMID:37723098 | DOI:10.1080/10749357.2023.2175421
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Soheila Fallah Ghorban Taghizadeh Zahra Parnain Moslem Cheraghifard Parvaneh Taghavi Azar Sharabiani Mahin Yousefi Mohammad Taghi Joghataei Ali Gholizade Source Type: research

Impact of rehabilitation adherence and depressive symptoms on post-stroke self-care ability and quality of life: a longitudinal study
CONCLUSION: Both depressive symptoms and rehabilitation adherence behavior impacted the rehabilitation effect among patients who are recovering from a stroke.PMID:37722691 | DOI:10.1080/10749357.2023.2259652
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Jeng Wang Wen-Yu Kuo Min-Chi Chen Chen-Yin Chen Source Type: research

Effectiveness of mid thoracic spine mobilization on postural balance and gait ability in subacute stroke patients: A randomized clinical trial
CONCLUSIONS: Mid-thoracic spine mobilization allows significant improvements in postural balance and gait ability in subacute stroke patients, with no differences between the SNAG and MM techniques.PMID:37718778 | DOI:10.3233/BMR-230144
Source: Journal of Back and Musculoskeletal Rehabilitation - September 18, 2023 Category: Orthopaedics Authors: Jinhong Kim Juchul Cho Source Type: research

Reliability and validity of the supine-to-stand test in people with stroke
CONCLUSION: The supine-to-stand test is a reliable, sensitive, specific and easy-to-administer clinical test for assessing the supine-to-stand ability of people with stroke.PMID:37721097 | DOI:10.2340/jrm.v55.12372
Source: Journal of Rehabilitation Medicine - September 18, 2023 Category: Rehabilitation Authors: Shamay S M Ng Peiming Chen Tony C W Chan Cherry H L Chang Regen H Y Cheng Kylie K L Chow Alex F M Yeung Tai-Wa Liu Lily Y W Ho Jerry W F Yeung Richard H Xu Mimi M Y Tse Source Type: research

Association of thyroid peroxidase antibody with the RNF213 p.R4810K variant in ischemic stroke/transient ischemic attack
CONCLUSIONS: Elevated TPO-Ab levels may be significantly associated with presence of the RNF213 p. R4810K variant in IS/TIA patients. Thus, TPO-Ab may inherently modify IS/TIA development in RNF213 p. R4810K variant carriers.PMID:37722316 | DOI:10.1016/j.atherosclerosis.2023.117281
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Takeshi Yoshimoto Hiroyuki Ishiyama Yorito Hattori Kunihiro Nishimura Yoko Okada Hideaki Watanabe Yasumasa Ohyagi Yasuhisa Akaiwa Tomoyuki Miyamoto Michi Kawamoto Masahiko Ichijo Hiroyasu Inoue Noriyuki Matsukawa Toshiki Mizuno Hirofumi Matsuyama Hidekazu Source Type: research

Atherosclerosis as a Risk Factor for IBD: A Population-Based Case-Control Study
CONCLUSIONS: A history of an atherosclerotic-related condition is associated with increased odds of developing IBD, particularly among older adults. Future studies should investigate whether drugs targeting atherosclerotic-related inflammation may prevent IBD in higher-risk individuals.PMID:37721310 | DOI:10.14309/ajg.0000000000002502
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Adam S Faye Jordan Axelrad Jiangwei Sun Jonas Halfvarson Jonas S öderling Ola Ol én Jonas F Ludvigsson Source Type: research

Phenylethanoid glycosides derived from Cistanche deserticola promote neurological functions and the proliferation of neural stem cells for improving ischemic stroke
This study aims to investigate whether PhGs treatment improves the stroke and its potential mechanisms. Adult male C57BL/6 J mice were administrated PhGs once daily for 7 days after MCAO surgery. The neurological score, and catwalk were evaluated on Day 1, 3 and 7 after ischemic stroke. Furthermore, triphenyl-2,3,5-tetrazoliumchloride (TTC) and hematoxylin-eosin (H&E) staining were used for evaluating the infarct volume and neuronal restoration. The effects of PhGs on NSCs proliferation were investigated in vitro and in vivo. Western blot was used to detect the proteins of Wnt/β-catenin signaling pathway. This study f...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 18, 2023 Category: Drugs & Pharmacology Authors: Jingjing Liu Yanyan Wang Qinyuan Li Tao Liu Xu Liu Han Zhang Zhifei Fu Yifan Dai Haiyuan Yang Yu Wang Ying Wang Source Type: research

Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research

A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
Microsyst Nanoeng. 2023 Sep 15;9:114. doi: 10.1038/s41378-023-00589-x. eCollection 2023.ABSTRACTThe ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network. Defective flow responses, in particular related to high flow conditions, have been associated with atherosclerosis, stroke, arteriovenous malformations, and neurodegenerative diseases. Yet, the molecular mechanisms involved in high flow response are still poorly understood. Here, we described the development and validation of a 96-wells fluidic system, w...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Catarina Gon çalves Fonseca V ânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco Source Type: research

SERPINA3: A novel inflammatory biomarker associated with cerebral small vessel disease burden in ischemic stroke
CONCLUSION: In summary, among four inflammatory biomarkers that we investigated, SERPINA3 level at baseline was associated with WMH severity, which revealed a novel biomarker for CSVD and validated its relationship with inflammation and endothelial dysfunction.PMID:37721405 | DOI:10.1111/cns.14472
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Xiao Hu Zhong-Song Xiao Yi-Qing Shen Wen-Song Yang Peng Wang Pei-Zheng Li Zi-Jie Wang Ming-Jun Pu Li-Bo Zhao Peng Xie Qi Li Source Type: research

Reliability of tomographic 3D ultrasound in measuring internal carotid artery plaque volume
CONCLUSION: t3DUS is a reproducible imaging method and showed excellent agreement with the reference standard with respect to measuring CPV. These findings suggest that t3DUS has the potential to be a valuable non-invasive tool for assessing carotid plaque burden and predicting the risk of stroke.PMID:37722861 | DOI:10.1177/02841851231199222
Source: Acta Radiologica - September 18, 2023 Category: Radiology Authors: Adel Alzahrani Salahaden R Sultan Mohammed Aslam Source Type: research

Role of TRPV1 in electroacupuncture-mediated signal to the primary sensory cortex during regulation of the swallowing function
CONCLUSION: The TRPV1 at CV23 after EA treatment might play a key role in mediating local blood perfusion but was not involved in transferring EA signals to the central nervous system (CNS). These findings collectively suggested that TRPV1 may be one of the important regulators involved in the mechanism of EA treatment for improving swallowing function in PSD.PMID:37718934 | DOI:10.1111/cns.14457
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Si Yuan Bo Qiu Ying Liang Bing Deng Jing Xu Xiaorong Tang Junshang Wu Sheng Zhou Zeli Li Hongzhu Li Qiuping Ye Lin Wang Shuai Cui Chunzhi Tang Wei Yi Lulu Yao Nenggui Xu Source Type: research

Neurophysiological characterization of stroke recovery: A  longitudinal TMS and EEG study
CONCLUSION: Our results demonstrate prominent clinical implications for individualized stroke rehabilitation based on both functional integrity of the ipsilesional corticomotor pathway and motor function.PMID:37718708 | DOI:10.1111/cns.14471
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qian Ding Jixiang Chen Shunxi Zhang Songbin Chen Xiaotong Li Yuan Peng Yujie Chen Junhui Chen Kang Chen Guiyuan Cai Guangqing Xu Yue Lan Source Type: research

Single-center experience of endovascular treatment for patients with progressive posterior circulation cerebral infarction exceeding 24 h
CONCLUSION: In patients with progressive posterior circulation cerebral infarction caused by vertebral basilar artery occlusion, ET is effective and safe even if the time from onset to puncture exceeds 24 h.PMID:37719319 | PMC:PMC10505061 | DOI:10.2478/abm-2023-0046
Source: Biomed Res - September 18, 2023 Category: Research Authors: Guangfeng Zhao Xiongjun He Yajie Liu Liang Zhang Kaifeng Li Source Type: research