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Total 202604 results found since Jan 2013.
Cerebral embolic protection during transcatheter heart interventions
EuroIntervention. 2023 Sep 18;19(7):549-570. doi: 10.4244/EIJ-D-23-00166.ABSTRACTStroke remains a devastating complication of transcatheter aortic valve replacement (TAVR), with the incidence of clinically apparent stroke seemingly fixed at around 3% despite TAVR's significant evolution during the past decade. Embolic showers of debris (calcium, atheroma, valve material, foreign material) are captured in the majority of patients who have TAVR using a filter-based cerebral embolic protection device (CEPD). Additionally, in systematic brain imaging studies, the majority of patients receiving TAVR exhibit new cerebral lesions...
Source: EuroIntervention - September 18, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Victor Alfonso Jimenez Diaz Samir R Kapadia Axel Linke Darren Mylotte Alexandra J Lansky Eberhard Grube Magnus Settergren Rishi Puri Source Type: research
Vasculitis associated with adenosine deaminase 2 deficiency: at the crossroads between Beh çet's disease and autoinflammation. A viewpoint
Reumatismo. 2023 Sep 18;75(3). doi: 10.4081/reumatismo.2023.1578.ABSTRACTAdenosine deaminase 2 deficiency (DADA2) is a rare monogenic vasculopathy caused by loss-of-function homozygous or compound heterozygous mutations in ADA2, formerly CECR1 (cat eye syndrome chromosome region 1) gene. The DADA2 phenotype is widely heterogeneous, and patients may present with fever, weight loss, livedo reticularis/racemosa, digital ischemia, cutaneous ulceration, peripheral neuropathy, abdominal pain, bowel perforation, and portal or nephrogenic hypertension. More specific manifestations include early-onset ischemic or hemorrhagic stroke...
Source: Reumatismo - September 18, 2023 Category: Rheumatology Authors: A Colangelo F Tromby G Cafaro R Gerli E Bartoloni C Perricone Source Type: research
Perceived Level of Life Enjoyment and Risk of Developing Disabling Dementia: The Japan Public Health Center-Based Study
DISCUSSION: A higher level of life enjoyment was associated with a lower risk of disabling dementia, particularly in the low-medium mental stress group. This finding suggests the importance of having life enjoyment by managing mental stress for reducing risk of disabling dementia.PMID:37718836 | DOI:10.1093/geronb/gbad129
Source: Cancer Control - September 18, 2023 Category: Cancer & Oncology Authors: Tomokazu Tajima Ai Ikeda Takeshi Tanigawa Hiroyasu Iso Kazumasa Yamagishi Takumi Matsumura Nobufumi Yasuda Manami Inoue Shoichiro Tsugane Norie Sawada Japan Public Health Center –Based Study Group Source Type: research
Triglyceride-glucose index and the risk of stroke in American adults: findings from the atherosclerosis risk in communities study
CONCLUSIONS: The TyG index independently predict stroke progression.PMID:37723527 | DOI:10.1186/s13098-023-01161-3
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Xinyi Wang Qiyu Liu Tongxin Wang Wende Tian Xuanye Chen Jie Zhang Qiuyi Li Dan Ma Lin Zhao Zhuo Chen Hao Xu Keji Chen Source Type: research
Angiography-based hemodynamic features predict recurrent ischemic events after angioplasty and stenting of intracranial vertebrobasilar atherosclerotic stenosis
CONCLUSIONS: In patients with intracranial vertebrobasilar atherosclerosis treated with PTAS, preprocedural prolonged TTP of the target vessel and shortened trans-stenotic TTP difference were associated with stroke relapse. Q-DSA-defined hemodynamic parameters provided incremental predictive value over conventional parameters for stroke recurrence.CLINICAL RELEVANCE STATEMENT: Quantitative DSA analysis enables intuitive observation and semi-quantitative evaluation of peri-therapeutic cerebral blood flow. More importantly, quantitative DSA-defined hemodynamic parameters have the potential for risk stratification of patients...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Kangmo Huang Weihe Yao Mingming Zha Shanmei Qin Yingle Li Yan Xu Rui Liu Ruidong Ye Yunfei Han Wusheng Zhu Zhongzhao Teng Juan Du Xinfeng Liu Source Type: research
Single-center experience of endovascular treatment for patients with progressive posterior circulation cerebral infarction exceeding 24 h
CONCLUSION: In patients with progressive posterior circulation cerebral infarction caused by vertebral basilar artery occlusion, ET is effective and safe even if the time from onset to puncture exceeds 24 h.PMID:37719319 | PMC:PMC10505061 | DOI:10.2478/abm-2023-0046
Source: Biomed Res - September 18, 2023 Category: Research Authors: Guangfeng Zhao Xiongjun He Yajie Liu Liang Zhang Kaifeng Li Source Type: research
Reliability of tomographic 3D ultrasound in measuring internal carotid artery plaque volume
CONCLUSION: t3DUS is a reproducible imaging method and showed excellent agreement with the reference standard with respect to measuring CPV. These findings suggest that t3DUS has the potential to be a valuable non-invasive tool for assessing carotid plaque burden and predicting the risk of stroke.PMID:37722861 | DOI:10.1177/02841851231199222
Source: Acta Radiologica - September 18, 2023 Category: Radiology Authors: Adel Alzahrani Salahaden R Sultan Mohammed Aslam Source Type: research
Understanding the Link Between Adult Asthma and Coronary Artery Disease: A Narrative Review
Cureus. 2023 Aug 17;15(8):e43621. doi: 10.7759/cureus.43621. eCollection 2023 Aug.ABSTRACTAsthma is a common pathology worldwide that occurs due to chronic inflammation of the respiratory airways. Persistent pulmonary inflammation leads to low-grade systemic inflammation, influencing blood vessels and triggering coronary artery disease (CAD) events. This review's objectives include discussing the susceptible population for CAD, the mechanism underlying CAD creation in asthma patients, the characteristics of asthma, and the influence of anti-asthmatic medications on CAD development. Adult-onset asthma is strongly linked to ...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Vasudha S Garg Mihir H Sojitra Tyagi J Ubhadiya Nidhi Dubey Karan Shah Siddharth Kamal Gandhi Priyansh Patel Source Type: research
A 96-wells fluidic system for high-throughput screenings under laminar high wall shear stress conditions
Microsyst Nanoeng. 2023 Sep 15;9:114. doi: 10.1038/s41378-023-00589-x. eCollection 2023.ABSTRACTThe ability of endothelial cells to respond to blood flow is fundamental for the correct formation and maintenance of a functional and hierarchically organized vascular network. Defective flow responses, in particular related to high flow conditions, have been associated with atherosclerosis, stroke, arteriovenous malformations, and neurodegenerative diseases. Yet, the molecular mechanisms involved in high flow response are still poorly understood. Here, we described the development and validation of a 96-wells fluidic system, w...
Source: Atherosclerosis - September 18, 2023 Category: Cardiology Authors: Catarina Gon çalves Fonseca V ânia Silvério David Barata Wolfgang Giese Holger Gerhardt Susana Cardoso Claudio Areias Franco Source Type: research
SERPINA3: A novel inflammatory biomarker associated with cerebral small vessel disease burden in ischemic stroke
CONCLUSION: In summary, among four inflammatory biomarkers that we investigated, SERPINA3 level at baseline was associated with WMH severity, which revealed a novel biomarker for CSVD and validated its relationship with inflammation and endothelial dysfunction.PMID:37721405 | DOI:10.1111/cns.14472
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Xiao Hu Zhong-Song Xiao Yi-Qing Shen Wen-Song Yang Peng Wang Pei-Zheng Li Zi-Jie Wang Ming-Jun Pu Li-Bo Zhao Peng Xie Qi Li Source Type: research
Role of TRPV1 in electroacupuncture-mediated signal to the primary sensory cortex during regulation of the swallowing function
CONCLUSION: The TRPV1 at CV23 after EA treatment might play a key role in mediating local blood perfusion but was not involved in transferring EA signals to the central nervous system (CNS). These findings collectively suggested that TRPV1 may be one of the important regulators involved in the mechanism of EA treatment for improving swallowing function in PSD.PMID:37718934 | DOI:10.1111/cns.14457
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Si Yuan Bo Qiu Ying Liang Bing Deng Jing Xu Xiaorong Tang Junshang Wu Sheng Zhou Zeli Li Hongzhu Li Qiuping Ye Lin Wang Shuai Cui Chunzhi Tang Wei Yi Lulu Yao Nenggui Xu Source Type: research
Neurophysiological characterization of stroke recovery: A longitudinal TMS and EEG study
CONCLUSION: Our results demonstrate prominent clinical implications for individualized stroke rehabilitation based on both functional integrity of the ipsilesional corticomotor pathway and motor function.PMID:37718708 | DOI:10.1111/cns.14471
Source: CNS Neuroscience and Therapeutics - September 18, 2023 Category: Neuroscience Authors: Qian Ding Jixiang Chen Shunxi Zhang Songbin Chen Xiaotong Li Yuan Peng Yujie Chen Junhui Chen Kang Chen Guiyuan Cai Guangqing Xu Yue Lan Source Type: research
Effectiveness of mid thoracic spine mobilization on postural balance and gait ability in subacute stroke patients: A randomized clinical trial
CONCLUSIONS: Mid-thoracic spine mobilization allows significant improvements in postural balance and gait ability in subacute stroke patients, with no differences between the SNAG and MM techniques.PMID:37718778 | DOI:10.3233/BMR-230144
Source: Journal of Back and Musculoskeletal Rehabilitation - September 18, 2023 Category: Orthopaedics Authors: Jinhong Kim Juchul Cho Source Type: research
Reliability and validity of the supine-to-stand test in people with stroke
CONCLUSION: The supine-to-stand test is a reliable, sensitive, specific and easy-to-administer clinical test for assessing the supine-to-stand ability of people with stroke.PMID:37721097 | DOI:10.2340/jrm.v55.12372
Source: Journal of Rehabilitation Medicine - September 18, 2023 Category: Rehabilitation Authors: Shamay S M Ng Peiming Chen Tony C W Chan Cherry H L Chang Regen H Y Cheng Kylie K L Chow Alex F M Yeung Tai-Wa Liu Lily Y W Ho Jerry W F Yeung Richard H Xu Mimi M Y Tse Source Type: research
Polypharmacy and Bleeding Outcomes After Percutaneous Coronary Intervention
CONCLUSIONS: In a real-world population of patients undergoing PCI, approximately 90% were on ≥5 medications. Increasing number of medications was associated with a higher adjusted risk for major bleeding, but not ischemic events.PMID:37722886 | DOI:10.1253/circj.CJ-23-0558
Source: Circulation Journal - September 18, 2023 Category: Cardiology Authors: Ko Yamamoto Takeshi Morimoto Masahiro Natsuaki Hiroki Shiomi Neiko Ozasa Hiroki Sakamoto Yasuaki Takeji Takenori Domei Takeshi Tada Ryoji Taniguchi Takashi Uegaito Miho Yamada Teruki Takeda Hiroshi Eizawa Satoru Suwa Manabu Shirotani Toshihiro Tamura Mori Source Type: research
