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Higenamine regulates Nrf2-HO-1-Hmgb1 axis and attenuates intestinal ischemia–reperfusion injury in mice
Conclusion Our study provides evidence HG regulates Nrf2-HO-1-Hmgb1 axis and attenuates intestinal IR injury in mice.
Source: Inflammation Research - May 1, 2015 Category: Research Source Type: research

Murine portal vein catheterization to analyze liver-directed therapies
Conclusions: Liver-directed therapy can provide the selective delivery of siRNA to CRC metastases. EpCAM expression in CRC, but not normal liver, could further selectively target hepatic metastases of epithelial origin.
Source: Journal of Surgical Research - July 18, 2013 Category: Surgery Authors: Joseph D. Valentino, Piotr G. Rychahou, W. Conan Mustain, Victoria A. Elliott, B. Mark Evers Tags: Oncology/Endocrine Source Type: research