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Total 106 results found since Jan 2013.
Silencing MMP7 expression with a lung-targeted RNAi molecule limits fibrosis and preserves pulmonary function in bleomycin-injured rats
Conclusions: Integrin targeting ligand-conjugated siRNAs potently silence MMP7 expression, limit fibrosis and improve lung function in the rat bleomycin model. ARO-MMP7 is a promising new therapeutic candidate for the treatment of IPF.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Yuan, T., Nicholas, A., Lakomski, N., Afrazi, M., Hamilton, H., Hegge, J., Hamilton, J., Pei, T., Bush, E. Tags: 12.01 - Idiopathic interstitial pneumonias Source Type: research
WDSUB1 knockdown alleviates dextran sulfate sodium-induced colitis in mice by inhibiting nuclear factor- κB signaling pathway
CONCLUSION: WDSUB1 knockdown can alleviate DSS- induced colitis in mice possibly by inhibiting the NF-κB signaling pathway and decreasing the expression of inflammatory factors in the colon tissues.PMID:36073209 | DOI:10.12122/j.issn.1673-4254.2022.08.02
Source: Journal of Southern Medical University - September 8, 2022 Category: Universities & Medical Training Authors: S Wang L Cui X Liu Z Luo H Li J Pu Source Type: research
