Filtered By:
Nutrition: Potassium
This page shows you your search results in order of date.
Order by Relevance | Date
Total 74 results found since Jan 2013.
RACK1 mediates NLRP3 inflammasome activation during Pasteurella multocida infection
This study shows that RACK1 expression was downregulated by PmCQ2 infection in primary mouse peritoneal macrophages and mouse tissues, and overexpression of RACK1 prevented PmCQ2-induced cell death and reduced the numbers of adherent and invasive PmCQ2, indicating a modulatory role of RACK1 in the cell death that is induced by P. multocida infection. Next, RACK1 knockdown by siRNA significantly attenuated PmCQ2-induced NLRP3 inflammasome activation, which was accompanied by a reduction in the protein expression of interleukin (IL)-1β, pro-IL-1β, caspase-1 and NLRP3 as well as the formation of ASC specks, while RACK1 over...
Source: Cell Research - September 8, 2023 Category: Cytology Authors: Jinrong Ran Hang Yin Yating Xu Yu Wang Gang Li Xingping Wu Lianci Peng Yuanyi Peng Rendong Fang Source Type: research
The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia
Am J Physiol Cell Physiol. 2023 May 1. doi: 10.1152/ajpcell.00374.2022. Online ahead of print.ABSTRACTControl of the movement of ions and water across epithelia is essential for homeostasis. Changing the number or activity of ion channels at the plasma membrane is a significant regulator of epithelial transport. In polarized epithelia, the intermediate-conductance calcium-activated potassium channel, KCa3.1 is delivered to the basolateral membrane where it generates and maintains the electrochemical gradients required for epithelial transport. The mechanisms that control the delivery of KCa3.1 to the basolateral membrane a...
Source: American Journal of Physiology. Cell Physiology - May 1, 2023 Category: Cytology Authors: Matthew J E Logue Rachel E Farquhar Yoakim Eckhoff-Bj örngard Tanya T Cheung Daniel C Devor Fiona J McDonald Kirk L Hamilton Source Type: research
Silence of URI in gastric cancer cells promotes cisplatin-induced DNA damage and apoptosis
In conclusion, our results suggest that URI is involved in the cisplatin-induced DNA damage response via the ATM/CHK2 pathway, and silencing URI can increase cisplatin-induced DNA damage and enhance drug sensitivity in gastric cancer cells.PMID:37034221 | PMC:PMC10077030
Source: Cell Research - April 10, 2023 Category: Cytology Authors: Huiqin Bian Yu Gu Chen Chen Jinnan Chen Fei Zhang Zhonghai Xu Qian Wang Rui Mi Xuan Wu Yaojuan Lu Qiping Zheng Junxia Gu Source Type: research
