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Total 77 results found since Jan 2013.

CLEC4A and CLEC12B C-type lectin receptors mediate interactions with < em > Pneumocystis < /em > cell wall components
Conclusion. The data presented here provide new members of the CLRs family recognizing Pneumocystis. Future studies using CLEC4A and/or CLEC12B deficient mice in the PCP mouse model should provide further insights into the host immunological response to Pneumocystis.PMID:37294293 | DOI:10.1099/jmm.0.001714
Source: Journal of Medical Microbiology - June 9, 2023 Category: Microbiology Authors: Theodore J Kottom Eva M Carmona Kyle Schaefbauer Andrew H Limper Source Type: research

Suppression of galectin-4 attenuates peritoneal metastasis of poorly differentiated gastric cancer cells
ConclusionsWe clarified the role of galectin-4 in the development of peritoneal dissemination of poorly differentiated gastric cancer cells. Our data highlight the diagnostic and therapeutic potential of galectin-4 in the peritoneal dissemination of gastric cancer.
Source: Gastric Cancer - January 25, 2023 Category: Gastroenterology Source Type: research

Sialyl Lewis X mediates interleukin-1 beta induced trophoblast adhesion to endometrial cells during human embryo implantation
Biol Reprod. 2023 Jan 16:ioad007. doi: 10.1093/biolre/ioad007. Online ahead of print.ABSTRACTCell surface carbohydrate antigens sialyl Lewis X (sLeX) and Lewis Y (LeY) are paramount glycoconjugates and are abundantly expressed in the receptive endometrium. Furthermore, among the important biological functions of both antigens is their role in leukocytes adhesion and extravasation. Interleukin-1 beta (IL-1β) is involved in the process of human embryo implantation and placenta development. Here we used an in vitro model to investigate whether sLeX and LeY are playing a role in the embryo implantation process mediated by IL-...
Source: Biology of Reproduction - January 17, 2023 Category: Reproduction Medicine Authors: Zhi Ma Mirjana Kessler Anca Chelariu-Raicu Markus Sperandio Sven Mahner Udo Jeschke Viktoria von Sch önfeldt Source Type: research