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Molecular characterization of p38 MAPK from blunt snout bream (Megalobrama amblycephala) and its expression after ammonia stress, and lipopolysaccharide and bacterial challenge
Publication date: January 2019Source: Fish & Shellfish Immunology, Volume 84Author(s): Chun-Nuan Zhang, Samad Rahimnejad, Kang-Le Lu, Wen-Hao Zhou, Ji-Liang ZhangAbstractp38 mitogen-activated protein kinase (MAPK) is an important protein which plays a key role in regulating the innate immunity, so exploring its molecular characterization is helpful in understanding the resistance against microbial infections in cultured fish. Here, a full-length cDNA of p38 MAPK was cloned from liver of blunt snout bream (Megalobrama amblycephala) which covered 2419 bp with an open reading frame of 1086 bp encoding 361 amino acids. p38 MAP...
Source: Fish and Shellfish Immunology - November 4, 2018 Category: Biology Source Type: research

Identification and functional analysis of the Toll-like receptor 20.2 gene in grass carp, Ctenopharyngodon idella.
This study increases understanding of the immune system in C. idella. PMID: 27370974 [PubMed - as supplied by publisher]
Source: Developmental and Comparative Immunology - June 27, 2016 Category: Allergy & Immunology Authors: Huang WJ, Wang X, Shen Y, Xu XA, Li L, Wang R, Li J Tags: Dev Comp Immunol Source Type: research

Identification, characterization, and functional studies of a Pelle gene in the Chinese mitten crab, Eriocheir sinensis
Publication date: August 2015 Source:Fish & Shellfish Immunology, Volume 45, Issue 2 Author(s): Ying Huang , Yi-Hong Chen , Yu-Zhou Zhang , Jin-Ling Feng , Ling-Ling Zhao , Huan-Xi Zhu , Wen Wang , Qian Ren The toll-like receptor/NF-κB signaling pathways play an important role in the innate immune system. In the present study, one Pelle gene (named EsPelle) was identified for the first time from the Chinese mitten crab Eriocheir sinensis. The full-length cDNA of EsPelle is 3797 bp with a 3156 bp-long open reading frame that encodes a 1051 amino acid protein. EsPelle protein contains a death domain at the N-ter...
Source: Fish and Shellfish Immunology - June 15, 2015 Category: Biology Source Type: research

Identification and molecular characterization of a peritrophin-like gene, involved in the antibacterial response in Chinese mitten crab, Eriocheir sinensis.
In this study, a peritrophin-like gene (EsPT) was obtained from Eriocheir sinensis. The full length cDNA of EsPT was 1232 bp, which contained 1005 bp ORF encoding a protein of 334 amino acids, including a 22 amino acid signal peptide, and 3 conserved chitin binding type 2 domains (ChtBD2) characterized by having a 6-cysteine motif. Phylogenetic analysis showed that EsPT was clustered together with 2 insect peritrophin-44-like proteins (MdP44L from Musca domestica and CcP44L from Ceratitis capitata), an insect chitin binding peritrophin-A domain containing protein (CfPT from Coptotermes formosanus) and a crustacean peritrop...
Source: Developmental and Comparative Immunology - January 14, 2015 Category: Allergy & Immunology Authors: Huang Y, Ma F, Wang W, Ren Q Tags: Dev Comp Immunol Source Type: research