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Infectious Disease: Aspergillus

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Total 48 results found since Jan 2013.

Quercetin protects against Aspergillus fumigatus keratitis by reducing fungal load and inhibiting TLR-4 induced inflammatory response
CONCLUSION: Quercetin plays a protective role in mouse A. fumigatus keratitis by inhibiting fungal load, disrupting hyphae structure, macrophage infiltration, and suppressing inflammation response in macrophages via TLR-4 mediated signaling pathway.PMID:37677994 | DOI:10.1016/j.cyto.2023.156356
Source: Cytokine - September 7, 2023 Category: Molecular Biology Authors: Junjie Luan Yunan Zhu Jing Lin Yingxue Zhang Qiang Xu Lu Zhan Xue Tian Guiqiu Zhao Xudong Peng Source Type: research

Inhibition of cGAS aggravated the host inflammatory response to < em > Aspergillus fumigatus < /em >
Conclusion: Based on our analysis, we conclude that activating cGAS might increase host resistance to A. fumigatus, protect against pulmonary illnesses brought on by A. fumigatus and that exploring the cGAS-STING signaling pathway is beneficial not only for the immunological investigation of IPA but also may be a potential therapeutic objective.PMID:37190937 | DOI:10.1080/01902148.2023.2211663
Source: Experimental Lung Research - May 16, 2023 Category: Respiratory Medicine Authors: Mei Peng Xiujun Li Xiaobing Zhang Li Peng Source Type: research