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Source: Molecular Carcinogenesis

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Total 68 results found since Jan 2013.

Lymphotoxin ‐β receptor‐NIK signaling induces alternative RELB/NF‐κB2 activation to promote metastatic gene expression and cell migration in head and neck cancer
This article is protected by copyright. All rights reserved
Source: Molecular Carcinogenesis - November 22, 2018 Category: Molecular Biology Authors: Rita Das, Jamie Coupar, Paul E. Clavijo, Anthony Saleh, Tsu ‐Fan Cheng, Xinping Yang, Jianhong Chen, Carter VanWaes, Zhong Chen Tags: RESEARCH ARTICLE Source Type: research

Pro ‐inflammatory M1 Macrophage enhances metastatic potential of ovarian cancer cells through NF‐κB activation
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Source: Molecular Carcinogenesis - October 12, 2017 Category: Molecular Biology Authors: Untack Cho, Boyun Kim, Soochi Kim, Youngjin Han, Yong Sang Song Tags: RESEARCH ARTICLE Source Type: research

Metabolite of ellagitannins, urolithin A induces autophagy and inhibits metastasis in human sw620 colorectal cancer cells
This study found that submicromolar concentrations of urolithin A, a major polyphenol metabolite, induced autophagy in SW620 colorectal cancer (CRC) cells. Exposure to urolithin A also dose‐dependently decreased cell proliferation, delayed cell migration and decreased matrix metalloproteinas‐9 (MMP‐9) activity. In addition, inhibition of autophagy by Atg5‐siRNA, caspases by Z‐VAD‐FMK suppressed urolithin A‐ stimulated cell death and anti‐metastatic effects. Micromolar urolithin A concentrations induced both autophagy and apoptosis. Urolithin A suppressed cell cycle progression and inhibited DNA synthesis. T...
Source: Molecular Carcinogenesis - October 4, 2017 Category: Molecular Biology Authors: Wenhua Zhao, Fengqiang Shi, Zhikun Guo, Jiaojie Zhao, Xueying Song, Hua Yang Tags: RESEARCH ARTICLE Source Type: research

TNFAIP8 regulates Hippo pathway through interacting with LATS1 to promote cell proliferation and invasion in lung cancer
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Source: Molecular Carcinogenesis - September 19, 2017 Category: Molecular Biology Authors: Yong Han, ZhongPing Tang, Yue Zhao, Qingchang Li, Enhua Wang Tags: RESEARCH ARTICLE Source Type: research

p0071 interacts with E ‐cadherin in the cytoplasm so as to promote the invasion and metastasis of non‐small cell lung cancer
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Source: Molecular Carcinogenesis - September 12, 2017 Category: Molecular Biology Authors: Huanyu Zhao, Di Zhang, Lianhe Yang, Enhua Wang Tags: RESEARCH ARTICLE Source Type: research

Lasp2 enhances tumor invasion via facilitating phosphorylation of FAK and predicts poor overall survival of non ‐small cell lung cancer patients
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Source: Molecular Carcinogenesis - July 1, 2017 Category: Molecular Biology Authors: Xiupeng Zhang, Lin Cai, Haijing Zhou, Yang Liu, Chuifeng Fan, Liang Wang, Ailin Li, Yuan Miao, Qingchang Li, Xueshan Qiu, Enhua Wang Tags: RESEARCH ARTICLE Source Type: research

CCL20 promotes migration and invasiveness of human cancerous breast epithelial cells in primary culture
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Source: Molecular Carcinogenesis - June 15, 2017 Category: Molecular Biology Authors: Antonella Muscella, Carla Vetrugno, Santo Marsigliante Tags: RESEARCH ARTICLE Source Type: research

Inhibition of Glycogen Synthase Kinase 3 beta (GSK3 β) Suppresses the Progression of Esophageal Squamous Cell Carcinoma by Modifying STAT3 Activity
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Source: Molecular Carcinogenesis - June 2, 2017 Category: Molecular Biology Authors: Shegan Gao, Shuoguo Li, Xiaoxian Duan, Zhen Gu, Zhikun Ma, Xiang Yuan, Xiaoshan Feng, Huizhi Wang Tags: RESEARCH ARTICLE Source Type: research

UCP2 Upregulation Promotes PLC γ‐1 Signaling During Skin Cell Transformation
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Source: Molecular Carcinogenesis - June 1, 2017 Category: Molecular Biology Authors: Annapoorna Sreedhar, Julia Lefort, Petra Petruska, Xin Gu, Runhua Shi, Sumitra Miriyala, Manikandan Panchatcharam, Yunfeng Zhao Tags: RESEARCH ARTICLE Source Type: research

Vernodalol enhances TRAIL ‐induced apoptosis in diffuse large B‐cell lymphoma cells
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Source: Molecular Carcinogenesis - May 3, 2017 Category: Molecular Biology Authors: Wenjun Wu, Yang Yang, Gang Deng, Liang Ma, Guoqing Wei, Gaofeng Zheng, Xiaoyan Han, Donghua He, Yi Zhao, Jinsong He, Zhen Cai, Rui Yu Tags: RESEARCH ARTICLE Source Type: research

Copy number variation, increased gene expression, and molecular mechanisms of neurofascin in lung cancer
This study aimed at increasing the knowledge on the involvement of adhesion molecules in lung cancer progression by studying the regulation and role of NFASC in non‐small cell lung cancer (NSCLC). Here, copy number variations in the NFASC gene were analyzed in tumor and non‐tumorous lung tissues of 204 NSCLC patients. Frequent gene amplifications (OR = 4.50, 95%CI: 2.27‐8.92, P ≤ 0.001) and increased expression of NFASC (P = 0.034) were identified in tumors of NSCLC patients. Furthermore, molecular mechanisms of NFASC in lung cancer progression were evaluated by investigating the effects of NFASC silenc...
Source: Molecular Carcinogenesis - May 2, 2017 Category: Molecular Biology Authors: Johanna Samulin Erdem, Yke Jildouw Arnoldussen, Vidar Skaug, Aage Haugen, Shanbeh Zienolddiny Tags: RESEARCH ARTICLE Source Type: research

Copy number variation, increased gene expression and molecular mechanisms of Neurofascin in lung cancer
This study aimed at increasing the knowledge on the involvement of adhesion molecules in lung cancer progression by studying the regulation and role of NFASC in non‐small cell lung cancer (NSCLC). Here, copy number variations in the NFASC gene were analyzed in tumor and non‐tumorous lung tissues of 204 NSCLC patients. Frequent gene amplifications (OR = 4.50, 95% CI: 2.27‐8.92, P ≤ 0.001) and increased expression of NFASC (P = 0.034) were identified in tumors of NSCLC patients. Furthermore, molecular mechanisms of NFASC in lung cancer progression were evaluated by investigating the effects of NFASC silencing...
Source: Molecular Carcinogenesis - April 18, 2017 Category: Molecular Biology Authors: Johanna Samulin Erdem, Yke Jildouw Arnoldussen, Vidar Skaug, Aage Haugen, Shanbeh Zienolddiny Tags: RESEARCH ARTICLE Source Type: research

Kctd20 promotes the development of non ‐small cell lung cancer through activating Fak/AKT pathway and predicts poor overall survival of patients
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Source: Molecular Carcinogenesis - April 11, 2017 Category: Molecular Biology Authors: Xiupeng Zhang, Haijing Zhou, Lin Cai, Chuifeng Fan, Yang Liu, Liang Wang, Qingchang Li, Yuan Miao Tags: RESEARCH ARTICLE Source Type: research

(E) ‐2‐methoxy‐4‐(3‐(4‐methoxyphenyl)prop‐1‐en‐1‐yl)phenol suppresses ovarian cancer cell growth via inhibition of ERK and STAT3
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Source: Molecular Carcinogenesis - March 8, 2017 Category: Molecular Biology Authors: Jie Zheng, Dong Ju Son, Hye Lim Lee, Hee Pom Lee, Tae Hoon Kim, Jung Heun Joo, Young Wan Ham, Wun Jae Kim, Jae Kyung Jung, Sang ‐Bae Han, Jin Tae Hong Tags: RESEARCH ARTICLE Source Type: research

ABCF2, an Nrf2 target gene, contributes to cisplatin resistance in ovarian cancer cells
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Source: Molecular Carcinogenesis - January 22, 2017 Category: Molecular Biology Authors: Lingjie Bao, Jianfa Wu, Matthew Dodson, Elisa Montserrat Rojo de la Vega, Yan Ning, Zhenbo Zhang, Ming Yao, Donna D. Zhang, Congjian Xu, Xiaofang Yi Tags: RESEARCH ARTICLE Source Type: research