Filtered By:
Drug: Ibuprofen
This page shows you your search results in order of date.
Order by Relevance | Date
Total 9 results found since Jan 2013.
Increased expression of ZNF 703 in breast cancer tissue: An opportunity for RNAi –NSAID combinatorial therapy
We report that the combination of anti‐ZNF703 RNAi with ibuprofen as the inhibitor of COX‐2 is highly effective in inhibiting MCF‐7 as a breast cancer cell line and shows therapeutic potential for breast cancer.
Source: Biotechnology and Applied Biochemistry - June 23, 2019 Category: Biochemistry Authors: Marzieh Marzbany,
Anupam Bishayee,
Mahsa Rasekhian Tags: Original Article Source Type: research
Increased expression of ZNF 703 in breast cancer tissue: An opportunity for RNAi ‐ NSAID combinatorial therapy
This article is protected by copyright. All rights reserved
Source: Biotechnology and Applied Biochemistry - June 12, 2019 Category: Biochemistry Authors: Marzieh Marzbany,
Anupam Bishayee,
Mahsa Rasekhian Tags: Original Article Source Type: research
GSE122074 Nfat5 is involved in the hyperosmotic regulation of Tmem184b, which could be involved in ibuprofen transport in renal MDCK I cells
Conclusion: The regulation of Tmem184b was found regulated by Nfat5 and could be a potential possible candidate for the gene product responsible for the uptake of ibuprofen in MDCK I cells
Source: GEO: Gene Expression Omnibus - May 10, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Canis lupus familiaris Source Type: research
Therapeutic mechanisms of ibuprofen, prednisone and betamethasone in osteoarthritis.
In conclusion, prednisone, ibuprofen and betamethasone may prevent OA by suppressing the expression of IL‑6 and IL‑8, subsequently inactivating NF‑κB and STAT3 pathways, and ultimately, leading to decreased levels of collagen I, MMP‑1, and MMP‑13.
PMID: 28035387 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - January 1, 2017 Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Inhibition of cyclooxygenase‐1 and ‐2 activity in keratinocytes inhibits PGE2 formation and impairs vascular endothelial growth factor release and neovascularisation in skin wounds
This study investigated the role of Cox activity in the regulation of vascular endothelial growth factor (VEGF) expression in keratinocytes and the formation of new blood vessels in acute wounds in mice. To this end, human HaCaT keratinocytes were stimulated with epidermal growth factor (EGF). EGF increased Cox‐1 mRNA in the presence of the constitutively expressed Cox‐1 protein in keratinocytes. EGF coinduced Cox‐2 and VEGF165 mRNA and protein expression and an accumulation of prostaglandin E2 (PGE2) in cell culture supernatants. Inhibition of Cox isozyme activity by Cox‐1 and ‐2 siRNA or ibuprofen reduced PGE2 ...
Source: International Wound Journal - December 17, 2015 Category: Surgery Authors: Itamar Goren, Seo‐Youn Lee, Damian Maucher, Rolf Nüsing, Thomas Schlich, Josef Pfeilschifter, Stefan Frank Tags: ORIGINAL ARTICLE Source Type: research
Inhibition of cyclooxygenase ‐1 and ‐2 activity in keratinocytes inhibits PGE2 formation and impairs vascular endothelial growth factor release and neovascularisation in skin wounds
This study investigated the role of Cox activity in the regulation of vascular endothelial growth factor (VEGF) expression in keratinocytes and the formation of new blood vessels in acute wounds in mice. To this end, human HaCaT keratinocytes were stimulated with epidermal growth factor (EGF). EGF increased Cox‐1 mRNA in the presence of the constitutively expressed Cox‐1 protein in keratinocytes. EGF coinduced Cox‐2 and VEGF165 mRNA and protein expression and an accumulation of prostaglandin E2 (PGE2) in cell culture supernatants. Inhibition of Cox isozyme activity by Cox‐1 and ‐2 siRNA or ibuprofen reduced PGE2 ...
Source: International Wound Journal - December 16, 2015 Category: Surgery Authors: Itamar Goren, Seo ‐Youn Lee, Damian Maucher, Rolf Nüsing, Thomas Schlich, Josef Pfeilschifter, Stefan Frank Tags: ORIGINAL ARTICLE Source Type: research
Major involvement of Na+‐dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells
This study is the first to confirm expression of SLC5A6 in human brain microvessels and to provide evidence that SLC5A6 is a major contributor to luminal uptake of biotin and pantothenic acid at the human BBB.
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - March 21, 2015 Category: Neurology Authors: Yasuo Uchida, Katsuaki Ito, Sumio Ohtsuki, Yoshiyuki Kubo, Takashi Suzuki, Tetsuya Terasaki Tags: Original Article Source Type: research
