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Condition: Rheumatoid Arthritis
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Total 292 results found since Jan 2013.
Regulatory effect of zinc finger protein A20 on rheumatoid arthritis through NLRP3/Caspase-1 signaling axis mediating pyroptosis of HFLS- RA cells
In conclusion, this study is of great significance for understanding the role of the NLRP3-caspase-1-IL-1β/ pyroptosis signaling pathway in the occurrence and development of RA. It is expected that the results will provide a theoretical basis for the immune regulation of innate immunity in the occurrence and development of RA, while providing a new therapeutic target for the clinical treatment of RA.PMID:37715399 | DOI:10.14715/cmb/2023.69.8.27
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Ziqin Zhao Xinlong Ma Shuhui Dong Haibo Yin Yong Yang Guangyi Xiong Source Type: research
Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis
ConclusionThe FGF pathway is a critical signaling pathway in relapse RA. Targeted tissue-specific inhibition of FGF10/FGFR1 may provide new opportunities to treat patients with relapse RA.
Source: Arthritis and Rheumatology - August 16, 2023 Category: Rheumatology Authors: Xiaohui Meng,
Zechuan Chen,
Teng Li,
Zhixing Nie,
Haihui Han,
Sheng Zhong,
Zhinan Yin,
Songtao Sun,
Jun Xie,
Jun Shen,
Xirui Xu,
Chenxin Gao,
Lei Ran,
Bo Xu,
Zheng Xiang,
Jianye Wang,
Pengfei Sun,
Pengfei Xin,
Xinyu A,
Chengbo Zhang,
G Tags: Full Length Source Type: research
Anti-HPV16 oncoproteins siRNA therapy for cervical cancer using a novel transdermal peptide PKU12
In conclusion, the transdermal peptide PKU12 is potentially a good candidate for a siRNA delivery vehicle for the treatment of cervical cancer.PMID:37350944 | PMC:PMC10282752 | DOI:10.3389/fonc.2023.1175958
Source: Cancer Control - June 23, 2023 Category: Cancer & Oncology Authors: Yan Deng Yi Song Quan Du Chi Chiu Wang Hu Li Yi Sui Yuying Zhang Tao Tang Source Type: research
CD5L aggravates rheumatoid arthritis progression via promoting synovial fibroblasts proliferation and activity
In conclusion, CD5L promote RA disease progression via activating RASFs. CD5L blocking is a potential therapeutic approach for RA patients.PMID:37191481 | DOI:10.1093/cei/uxad054
Source: Clinical and Developmental Immunology - May 16, 2023 Category: Allergy & Immunology Authors: Xia-Nan Wu Zhao-Wei Gao Lan Yang Juan Zhang Chong Liu Hui-Zhong Zhang Ke Dong Source Type: research
