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Condition: Huntington's Disease

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Total 63 results found since Jan 2013.

A Feedback Loop between TGF- β1 and < em > ATG5 < /em > Mediated by miR-122-5p Regulates Fibrosis and EMT in Human Trabecular Meshwork Cells
Curr Issues Mol Biol. 2023 Mar 13;45(3):2381-2392. doi: 10.3390/cimb45030154.ABSTRACTAutophagy is a cell's evolutionary conserved process for degrading and recycling cellular proteins and removing damaged organelles. There has been an increasing interest in identifying the basic cellular mechanism of autophagy and its implications in health and illness during the last decade. Many proteinopathies such as Alzheimer's and Huntington's disease are reported to be associated with impaired autophagy. The functional significance of autophagy in exfoliation syndrome/exfoliation glaucoma (XFS/XFG), remains unknown though it is pres...
Source: Current Issues in Molecular Biology - March 28, 2023 Category: Molecular Biology Authors: Munmun Chakraborthy Aparna Rao Source Type: research