Insomnia and aggression in stable schizophrenic patients: the mediating role of quality of life - Zhou R, Ye M, Ouyang X, Zhang SF, Zheng SY, Wang R, Cao P, Yang K, Zhou X.
This study aimed to explore the potential mediating role... (Source: SafetyLit)
Source: SafetyLit - March 28, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

MRI reveals effects of risk factors on vulnerable brain regions
MRI shows the effects particular risk factors such as diabetes, air pollution, and frequency of alcohol use have on "higher-order" brain regions located in the cerebral cortex, researchers have found. A team led by Jordi Manuello, PhD, of the University of Oxford in the U.K. reported that these risk factors further increase an individual's vulnerability to conditions such as schizophrenia and Alzheimer's disease. The group's findings were published March 27 in Nature Communications. "[Our] results provide a comprehensive picture of the role played by genetic and modifiable risk factors on these fragile parts of the brain...
Source: AuntMinnie.com Headlines - March 27, 2024 Category: Radiology Authors: Kate Madden Yee Tags: Subspecialties MRI Neuroradiology Source Type: news

Medication non-adherence and self-inflicted violence behaviors among 185,800 patients with schizophrenia in the community: a 12-year cohort study - Zuo C, Yang X, Wu X, Fan R, Liu J, Xiang H, Li Y, Zhao X, Liu X, Liu Y.
BACKGROUND: Despite the importance of medication adherence in treatment effectiveness, little is known about the association between medication non-adherence and self-inflicted violence behaviors. We aimed to assess whether medication non-adherence increas... (Source: SafetyLit)
Source: SafetyLit - March 27, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

When do drugs trigger criminal behavior? A machine learning analysis of offenders and non-offenders with schizophrenia and comorbid substance use disorder - Bender EM, Machetanz L, von K änel R, Euler S, Kirchebner J, Günther MP.
The objective of this study is to explore the most distinguishing factors between offending and non-offending... (Source: SafetyLit)
Source: SafetyLit - March 25, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Suicide among healthcare workers: risk factors, prevention, and challenges - Qattan Y, Almarzooq H, Khoj R, Alzahrani A, Alotibi B, Areeshi W, Albakestani M, Alrohaili A, Alantar A, Alsughayir A, Alhumoud Z.
Mental health disorders, contributing considerably to the global disease burden, have seen a marked increase due to urbanization, economic challenges, and the COVID-19 pandemic. These disorders, encompassing a spectrum from anxiety to schizophrenia, signif... (Source: SafetyLit)
Source: SafetyLit - March 25, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Rare Condition Makes Others' Faces Appear'Demonic '
FRIDAY, March 22, 2024 -- Some people diagnosed with schizophrenia might instead be suffering from a rare visual condition that can cause other people ’s faces to appear “demonic,” a new study argues.The condition, called prosopometamorphopsia... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 22, 2024 Category: General Medicine Source Type: news

TMS Promising for Psychomotor Slowing in Schizophrenia TMS Promising for Psychomotor Slowing in Schizophrenia
Inhibitory repetitive TMS was associated with significant improvement in psychomotor slowing in schizophrenia, a new study suggested.Medscape Medical News (Source: Medscape Psychiatry Headlines)
Source: Medscape Psychiatry Headlines - March 20, 2024 Category: Psychiatry Tags: Psychiatry Source Type: news

EXPRESS: The relationship of the methylation status and polymorphism of glucocorticoid receptor gene (NR3C1) with attempted suicide or non-suicidal self-injury patients in schizophrenia - Oyaci Y, Yildirim YE, Aytac HM, Pehlivan S, Cetinay Aydin P.
We aim to investigate the methylation of NR3C1 gene promotor and NR3C1 BclI polymorphism in schizophrenia (SCZ) patients with attempted suicide or non-suicidal self-injury (NSSI). A sample of 112 patients with SCZ were included in the study. SCID-I was use... (Source: SafetyLit)
Source: SafetyLit - March 19, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Correlates of suicidal behaviors and genetic risk among United States veterans with schizophrenia or bipolar I disorder - Bigdeli TB, Barr PB, Rajeevan N, Graham DP, Li Y, Meyers JL, Gorman BR, Peterson RE, Sayward F, Radhakrishnan K, Natarajan S, Nielsen DA, Wilkinson AV, Malhotra AK, Zhao H, Brophy M, Shi Y, O'Leary TJ, Gleason T, Przygodzki R, Pyarajan S, Muralidhar S, Gaziano JM, Huang GD, Concato J, Siever LJ, Delisi LE, Kimbrel NA, Beckham JC, Swann AC, Kosten TR, Fanous AH, Aslan M, Harvey PD.
Persons diagnosed with schizophrenia (SCZ) or bipolar I disorder (BPI) are at high risk for self-injurious behavior, suicidal ideation, and suicidal behaviors (SB). Characterizing associations between diagnosed health problems, prior pharmacological treatm... (Source: SafetyLit)
Source: SafetyLit - March 18, 2024 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

MRI May Predict Who'll Respond Best to Schizophrenia Treatment
FRIDAY, March 15, 2024 -- Specialized brain scans may accurately predict whether a psychotic patient will go on to develop treatment-resistant schizophrenia, Dutch researchers report. The scan— called a neuromelanin-sensitive MRI, or NM-MRI... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 15, 2024 Category: General Medicine Source Type: news

Association of empathy with clinical symptoms and cognitive function in chronic schizophrenia patients with and without suicide attempts - Ma Z, Tian Y, Li J, Liu J, Wang DM, Zhang XY.
Cognitive impairment is recognized as a risk factor for suicide in schizophrenia (SZ) patients. Despite empathy being an important aspect of social cognition, the association between suicidal behavior and empathy has received little attention. We aimed to ... (Source: SafetyLit)
Source: SafetyLit - March 15, 2024 Category: International Medicine & Public Health Tags: Risk Factor Prevalence, Injury Occurrence Source Type: news

LSD Anxiety Win; Pimavanserin Schizophrenia Flop; 'Bright Light' for Depression?
(MedPage Today) -- In a phase IIb study, a single dose of an investigational LSD-containing drug (MM120) led to significantly greater reductions in 12-week scores on the Hamilton Anxiety Rating Scale compared with placebo, according to Mind Medicine... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - March 13, 2024 Category: Psychiatry Source Type: news

Schizophrenia Tied to Increased Cardiovascular Disease Risk Schizophrenia Tied to Increased Cardiovascular Disease Risk
Schizophrenia diagnosis increases the risk for myocardial infarction, angina, and other cardiovascular diseases, especially in women.Medscape Medical News (Source: Medscape FamilyMedicine Headlines)
Source: Medscape FamilyMedicine Headlines - March 13, 2024 Category: Primary Care Tags: Psychiatry Source Type: news

Acadia Pharma ’s stock falls 15% after failed drug trial
One of Acadia Pharma’s drugs failed to meet goals of a late-stage trial about a schizophrenia treatment.#acadiapharmas (Source: Reuters: Health)
Source: Reuters: Health - March 11, 2024 Category: Consumer Health News Source Type: news

Acadia to Stop Trials Of Antipsychotic Drug After It Fails Schizophrenia Study Acadia to Stop Trials Of Antipsychotic Drug After It Fails Schizophrenia Study
Acadia Pharmaceuticals said on Monday it does not plan to conduct further clinical trials of its antipsychotic drug, pimavanserin, after it failed to improve negative...Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 11, 2024 Category: Consumer Health News Tags: Psychiatry Source Type: news