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Total 5081 results found since Jan 2013.

Pulmonary follicular lymphoma showing diffuse micronodules mimicking sarcoidosis.
Authors: Takuma K, Eri H, Satoshi I, Takashi O PMID: 30333400 [PubMed - as supplied by publisher]
Source: Internal Medicine - October 20, 2018 Category: Internal Medicine Tags: Intern Med Source Type: research

The combination of EBUS-TBNA and the PAB antibody led to a successful treatment for lung cancer in a patient with asymptomatic sarcoidosis mimicking nodal metastasis
Publication date: Available online 18 October 2018Source: Respiratory Medicine Case ReportsAuthor(s): Mari Tone, Nobuyasu Awano, Minoru Inomata, Naoyuki Kuse, Tatsunori Jo, Hanako Yoshimura, Yoshiaki Furuhata, Tamiko Takemura, Toshio Kumasaka, Takehiro IzumoAbstractCorrect staging of lung cancer is important for the selection of the best therapy, but discriminating between lymphadenopathy from lung cancer and from sarcoidosis by imaging examinations is difficult. Additionally, distinguishing lymphadenopathy of sarcoidosis from sarcoid reactions which are sometimes caused by lung cancer is difficult on imaging and pathologi...
Source: Respiratory Medicine Case Reports - October 19, 2018 Category: Respiratory Medicine Source Type: research

Letters to the editor
It was with great interest we read the article by Dr. Collins and colleagues published in the August 2018 edition of Respiratory Medicine, titled “Sarcoidosis and IPF in the same patient-a coincidence, an association or a phenotype?” The authors describe the characteristics of a disease entity they coined “combined sarcoidosis and idiopathic pulmonary fibrosis (CSIPF)” [1]. We appreciate the authors’ efforts to shed light on this cl inical entity, which to date has sparked debate in terms of proper classification of patients who share radiographic and histopathologic features of sarcoidosis and idiopathic pulmonary fibrosis (IPF).
Source: Respiratory Medicine - October 18, 2018 Category: Respiratory Medicine Authors: Ramon Valentin, Ryan Hyde, Diana Gomez, Divya Patel Tags: Correspondence Source Type: research

Atezolizumab-induced sarcoid-like granulomatous reaction in a patient with urothelial cell carcinoma
Immunotherapy,Volume 10, Issue 14, Page 1189-1192, October 2018.
Source: Immunotherapy - October 17, 2018 Category: Allergy & Immunology Authors: Michael A Mitchell Kevin Hogan Kayvan Amjadi Source Type: research

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Efficacy of Remission-induction Regimen With Infliximab for Severe Extrathoracic Sarcoidosis (EFIRTES)
Condition:   Extrathoracic Sarcoidosis Interventions:   Drug: Infliximab;   Drug: Placebo Sponsor:   Assistance Publique - Hôpitaux de Paris Not yet recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

PET/MR Imaging In Patients With Cardiac Sarcoidosis
Condition:   Cardiac Sarcoidosis Interventions:   Other: 18F-FDG;   Drug: Prednisolone Sponsor:   University of Edinburgh Recruiting
Source: ClinicalTrials.gov - October 15, 2018 Category: Research Source Type: clinical trials

Cutaneous phaeohyphomycosis caused by Microsphaeropsis arundinis in a Japanese patient with cardiac sarcoidosis
The Journal of Dermatology, EarlyView.
Source: The Journal of Dermatology - October 15, 2018 Category: Dermatology Authors: Fukuko Hanashiro, Sayaka Yamaguchi, Ryoko Awazawa, Ayako Sano, Kenzo Takahashi Source Type: research

Hilar and mediastinal sarcoid-like reaction after the treatment of malignant tumors: imaging features and natural course on 18 F-FDG-PET/CT
ConclusionAfter the treatment of malignancies, benign sarcoid-like reaction was rarely observed during follow-up. Although sarcoid-like reaction appeared a long time after the treatment of malignancies, it frequently and spontaneously regressed in a relatively short period of time.
Source: Japanese Journal of Radiology - October 15, 2018 Category: Radiology Source Type: research

Bilateral & #8220;turkey ear & #8221; as a cutaneous manifestation of lupus vulgaris
Yingjie Lu, Hongmiao Wang, Hua Zheng, Xiao LiIndian Journal of Dermatology, Venereology, and Leprology 2018 84(6):687-689 Lupus vulgaris is a common form of cutaneous tuberculosis in China, mostly involving the head and neck region. Turkey ear is a clinically descriptive term, used for a massively enlarged earlobe with bluish-red or violaceous indurated plaques and nodules, which can be a sign of lupus vulgaris. A 47-year-old female presented with edema and reddish ulcerated lesions on both ears which was diagnosed as lupus vulgaris by conventional laboratory investigations and the patient showed good response to antitube...
Source: Indian Journal of Dermatology, Venereology and Leprology - October 15, 2018 Category: Dermatology Authors: Yingjie Lu Hongmiao Wang Hua Zheng Xiao Li Source Type: research

The natural history of cutaneous sarcoidosis. Clinical spectrum and histological analysis of 40 cases
International Journal of Dermatology, EarlyView.
Source: International Journal of Dermatology - October 11, 2018 Category: Dermatology Authors: Lidia Garc ía‐Colmenero, Julia M. Sánchez‐Schmidt, Carlos Barranco, Ramon M. Pujol Source Type: research

Acute sarcoidosis in a multiple sclerosis patient after alemtuzumab treatment.
CONCLUSION: Our case highlights the profound effect of alemtuzumab on the immune system and its possible risk for autoimmune complications. PMID: 30307371 [PubMed - as supplied by publisher]
Source: Nuklearmedizin - October 11, 2018 Category: Radiology Authors: Graf J, Ringelstein M, Lepka K, Schaller J, Quack H, Hartung HP, Aktas O, Albrecht P Tags: Mult Scler Source Type: research

Combined Sarcoidosis and Idiopathic Pulmonary Fibrosis (CSIPF):Genuine Disease Entity, Obscure Clinical Phenotype or Diagnostic Red Herring?
The diffuse parenchymal lung diseases (DPLDs), often collectively referred to as the interstitial lung diseases (ILDs), are a heterogeneous group of disorders that are classified together because of similar clinical, radiographic, physiologic, or pathologic manifestations [1]. Universal features of the DPLDs include cellular proliferation, inflammation and/or fibrosis within the alveolar wall [2]. Architectural distortion of the airways and alveoli is also frequently present. The DPLDs are categorized into those that are associated with known causes and those that are idiopathic.
Source: Respiratory Medicine - October 6, 2018 Category: Respiratory Medicine Authors: Adam S. Morgenthau Tags: Editorial Source Type: research

Sarcoidosis: a benign disease or a culture of neglect?
The widespread perception that sarcoidosis is essentially a benign disease has undoubtedly contributed to a lack of investment in sarcoidosis-related public health and research initiatives. Respiratory clinicians managing both pulmonary sarcoidosis and idiopathic pulmonary fibrosis may be especially likely to subscribe to this view. Unlike most other forms of fibrotic lung disease, pulmonary sarcoidosis stabilizes with time, with or without therapy, in the majority of patients. Sarcoidosis patients with major cardiac or neurologic involvement are often managed by sub-specialists and may be under-represented in general sarcoidosis cohorts.
Source: Respiratory Medicine - October 6, 2018 Category: Respiratory Medicine Authors: Athol U. Wells Tags: Editorial Source Type: research

Bone sarcoidosis
Publication date: October 2018Source: Joint Bone Spine, Volume 85, Issue 5Author(s): Agathe Farge, Pauline Baudart, Sarah Jafari, Christian Marcelli
Source: Joint Bone Spine - October 5, 2018 Category: Orthopaedics Source Type: research

Small fiber neuropathy: Diagnosis, causes, and treatment
Publication date: October 2018Source: Joint Bone Spine, Volume 85, Issue 5Author(s): Damien SèneAbstractSmall fiber neuropathy, which affects the sensory Aδ and C fibers, is now a major diagnostic and therapeutic challenge. Nearly 7% of the general population have chronic neuropathic pain responsible for severe quality-of-life impairments. Awareness must therefore be raised among clinicians of the somatosensory and autonomic symptoms that can reveal small fiber neuropathy, appropriate diagnostic investigations, most common causes, and best treatment options for each patient profile. To help achieve this goal, the presen...
Source: Joint Bone Spine - October 5, 2018 Category: Orthopaedics Source Type: research

Which is the proper reference tissue for measuring the change in FDG PET metabolic volume of cardiac sarcoidosis before and after steroid therapy?
ConclusionsWe measured FDG uptake in the liver and blood pool before and during steroid therapy. Steroid therapy increased the liver uptake but not the blood pool uptake. Our findings suggested that the DA uptake is a more suitable threshold than liver uptake to evaluate therapeutic effects using volume-based analysis of cardiac FDG PET.
Source: EJNMMI Research - October 5, 2018 Category: Radiology Source Type: research

Micropapular Cutaneous Sarcoidosis Reviewed
Conclusion: In our review there does not seem to be a clear link as to the definite cause of the MPCS. While the relationships to tuberculosis and autoimmunity seem to be often emphasized, there was no clear association with either etiology.Dermatology
Source: Dermatology - October 4, 2018 Category: Dermatology Source Type: research

Role of 18F FDG PET/CT in the diagnostic challenge of sarcoidosis
Publication date: Available online 26 September 2018Source: Revista Española de Medicina Nuclear e Imagen Molecular (English Edition)Author(s): Luz Pabón, Ana Melissa Álvarez
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - October 4, 2018 Category: Nuclear Medicine Source Type: research

Non-Human Leukocyte Antigen Antibody-Mediated Lung Transplant Rejection: The Other Anti-A.
Conclusion: This case highlights the clinical significance of AMR in lung allografts, as well as the need to investigate both HLA and non-HLA antibody sources in pulmonary transplant rejection refractory to treatment. PMID: 30275791 [PubMed]
Source: Ochsner Journal - October 4, 2018 Category: General Medicine Tags: Ochsner J Source Type: research

Granuloma multiforme: an uncommon differential for leprosy.
Abstract Granuloma multiforme (GM) is a chronic granulomatous skin condition which is clinically characterised by annular lesions mainly over sun-exposed areas and histologically by focal necrobiosis and histiocytic granulomas. Its significance lies in the fact that it can clinically resemble tuberculoid leprosy and hence it can be missed. Here, we report a case of GM from India in a 55-year-old female agriculturist, with multiple asymptomatic large annular rings of papules over the photo-distributed areas. Histopathology helps in confirming the diagnosis and in differentiating it from similar clinical and histolo...
Source: Tropical Doctor - October 4, 2018 Category: Tropical Medicine Authors: Bhatia S, Shenoi SD, Pai K, Ps S Tags: Trop Doct Source Type: research

Work ability before and after sarcoidosis diagnosis in Sweden
Information on how sarcoidosis affects one's ability to work is needed to clarify the burden of disease on the individual and society. Our aim was to describe the work ability of individuals with sarcoidosis before and after diagnosis compared to people without sarcoidosis.
Source: Respiratory Medicine - October 4, 2018 Category: Respiratory Medicine Authors: Elizabeth V. Arkema, Anders Eklund, Johan Grunewald, Gustaf Bruze Source Type: research

Histopathology of salivary glands.
Abstract Salivary gland (SG) biopsy is a technique broadly applied for the diagnosis of primary Sjögren's syndrome (pSS), lymphoma accompanying SS, sarcoidosis, amyloidosis, and IgG4-related disease The most peculiar feature of pSS on biopsy is focal lymphocytic sialadenitis. In the past, several histological scores have been reported in the literature to describe glandular involvement during pSS. However, the variability among centres in reporting glandular scores is one of the rationales behind the development of standardised consensus guidance. SGs as well as lacrimal glands are involved in up to 50% of patien...
Source: Reumatismo - October 3, 2018 Category: Rheumatology Authors: Carubbi F, Alunno A, Gerli R, Giacomelli R Tags: Reumatismo Source Type: research

Macrophage Polarization in Sarcoidosis: An Unexpected Accomplice?
PMID: 30281325 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory Cell and Molecular Biology - October 3, 2018 Category: Molecular Biology Authors: Standiford TJ Tags: Am J Respir Cell Mol Biol Source Type: research

Pseudo-Sarcoidosis Revealing MonoMAC Syndrome
Source: Journal of Clinical Immunology - October 2, 2018 Category: Allergy & Immunology Source Type: research

The efficacy and safety of electroanatomic mapping-guided endomyocardial biopsy: a systematic review
ConclusionsEAM-guided EMB is a safe and efficacious method and might improve test characteristics over conventional fluoroscopy-guided biopsy.
Source: Journal of Interventional Cardiac Electrophysiology - October 1, 2018 Category: Cardiology Source Type: research

Pirfenidone-Induced Sarcoid-Like Reaction: A Novel Complication.
We describe the development of lymphadenopathy or a sarcoid-like reaction following initiation of pirfenidone, a complication not previously reported. PMID: 30290953 [PubMed - in process]
Source: Chest - October 1, 2018 Category: Respiratory Medicine Authors: Kolaitis NA, Kukreja J, Jones KD, Hays SR, Leard LE Tags: Chest Source Type: research

Significant elevation of the levels of B-cell activating factor (BAFF) in patients with sarcoidosis
This study demonstrated that the BAFF levels in both the serum and BALF were positively correlated with the disease activity markers and disease severity. BAFF may be useful as an indicator of both the disease activity and severity.
Source: Clinical Rheumatology - October 1, 2018 Category: Rheumatology Source Type: research

Needs, Perceptions and Education in Sarcoidosis: A Live Interactive Survey of Patients and Partners
This study improves awareness of needs and perceptions of patients with sarcoidosis and their partners. Sarcoidosis leads to anxiety and psychological distress and impairs well-being of patients and their partners. Attention for psychological support, better disease education, and more supportive care for partners is warranted.
Source: Lung - October 1, 2018 Category: Respiratory Medicine Source Type: research

Cardiac sarcoidosis: a challenging diagnosis
Source: Clinical Research in Cardiology - October 1, 2018 Category: Cardiology Source Type: research

Sarcoidosis triggered by immune checkpoint blockade.
Authors: Heppt M, Niesert AC, Flaig M, Berking C PMID: 30264301 [PubMed - in process]
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - September 29, 2018 Category: Dermatology Tags: Hautarzt Source Type: research

Erythema nodosum.
CONCLUSIONS: As erythema nodosum is often a cutaneous manifestation of a systemic disease, a thorough search should be performed to reveal the underlying cause. PMID: 30269303 [PubMed - as supplied by publisher]
Source: World Journal of Pediatrics : WJP - September 29, 2018 Category: Pediatrics Authors: Leung AKC, Leong KF, Lam JM Tags: World J Pediatr Source Type: research

Advanced pulmonary sarcoidosis: long-term follow-up of 10 years or more.
Conference abstracts
Source: The Aspergillus Website - updates - September 27, 2018 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Echocardiography in Sarcoidosis
AbstractPurpose of ReviewCardiac sarcoidosis (CS) is associated with significant morbidity and mortality. The diagnosis of CS is challenging and typically one that is only entertained after many other conditions have been ruled out. A high index of suspicion is necessary in order to correctly determine appropriate testing for the disease. Transthoracic echocardiography is the most readily available imaging modality available to help establish a diagnosis in a potential patient. However, no one echocardiographic feature is pathognomonic.Recent FindingsOn echocardiography, unusual wall motion abnormalities, which do not fit ...
Source: Current Cardiology Reports - September 26, 2018 Category: Cardiology Source Type: research

Acute and Fulminant Myocarditis: a Pragmatic Clinical Approach to Diagnosis and Treatment
AbstractPurpose of ReviewTo review the clinical features of acute myocarditis, including its fulminant presentation, and present a pragmatic approach to the diagnosis and treatment, considering indications of American and European Scientific Statements and recent data derived by large contemporary registries.Recent FindingsPatients presenting with acute uncomplicated myocarditis (i.e., without left ventricular dysfunction, heart failure, or ventricular arrhythmias) have a favorable short- and long-term prognosis: these findings do not support the indication to endomyocardial biopsy in this clinical scenario. Conversely, pa...
Source: Current Cardiology Reports - September 26, 2018 Category: Cardiology Source Type: research

Echocardiography in Sarcoidosis
AbstractPurpose of ReviewCardiac sarcoidosis (CS) is associated with significant morbidity and mortality. The diagnosis of CS is challenging and typically one that is only entertained after many other conditions have been ruled out. A high index of suspicion is necessary in order to correctly determine appropriate testing for the disease. Transthoracic echocardiography is the most readily available imaging modality available to help establish a diagnosis in a potential patient. However, no one echocardiographic feature is pathognomonic.Recent FindingsOn echocardiography, unusual wall motion abnormalities, which do not fit ...
Source: Current Cardiology Reports - September 26, 2018 Category: Cardiology Source Type: research

Sarcoidosis: proteomics and new perspectives for improving personalized medicine.
Abstract INTRODUCTION: Through synergistic approaches integrating biomedical data from omics sciences to the clinical practice, precision medicine aims at more accurate identification of risk factors, characterization of endotypes, patient stratification, establishment of individualized therapy, and prediction of outcomes. Areas covered: This review evaluates the potential role of different -omics approaches for the development and application of Precision Medicine to sarcoidosis patients. This systemic and heterogeneous inflammatory disease is of unknown aetiology, affects people of any age and requires genotypic...
Source: Genomics Proteomics ... - September 25, 2018 Category: Genetics & Stem Cells Authors: Landi C, Carleo A, Cillis G, Rottoli P Tags: Expert Rev Proteomics Source Type: research

Cardiac Sarcoidosis Presenting as Complete Atrioventricular Block: Findings on PET/MRI.
Authors: Lee CH, Son JW, Kong EJ PMID: 30238713 [PubMed]
Source: Korean Circulation Journal - September 22, 2018 Category: Cardiology Tags: Korean Circ J Source Type: research

Endobronchial Ultrasound-guided Transbronchial Needle Aspiration Using 19-G Needle for Sarcoidosis
Conclusion: This series reports a higher diagnostic yield than most other published studies and opens platform for direct comparison of each available needle. It also adds to the safety data for this larger needle. In addition, it raises doubt into utility of TBLB for diagnosis of sarcoidosis, which can increase the procedural complications.
Source: Journal of Bronchology and Interventional Pulmonology - September 22, 2018 Category: Respiratory Medicine Tags: Original Investigations Source Type: research

Pretesticular and Testicular Effects of Systemic Sarcoidosis: A Case Report.
Conclusion: This case illustrates the difficulties faced in managing the fertility of men who develop systemic sarcoidosis. It also highlights the diagnostic and therapeutic challenges faced by physicians when presented with a case of systemic sarcoidosis. PMID: 30230796 [PubMed - in process]
Source: Journal of Reproductive Medicine - September 22, 2018 Category: Reproduction Medicine Tags: J Reprod Med Source Type: research