Prognostic Role of Interferon ‐λ3 in Anti–Melanoma Differentiation–Associated Gene 5–Positive Dermatomyositis‐Associated Interstitial Lung Disease
ConclusionSerum IFN λ3 is a promising biomarker for identifying patients at high risk of poor outcomes in anti-MDA5 antibody–positive DM-ILD. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - February 7, 2024 Category: Rheumatology Authors: Atsuki Fukada,
Tomoyuki Fujisawa,
Hironao Hozumi,
Keigo Koda,
Taisuke Akamatsu,
Yoshiyuki Oyama,
Yasuomi Satake,
Mitsuru Niwa,
Yusuke Kaida,
Hiroyuki Matsuda,
Koshi Yokomura,
Naoki Koshimizu,
Mikio Toyoshima,
Shiro Imokawa,
Dai Hashimoto,
A Tags: Full Length Source Type: research
Cancer risk and mortality in hospitalised patients with idiopathic inflammatory myopathies in Western Australia
CONCLUSION: Cancer risk is not increased prior to IIM, but CIR for lung cancer is increased following DM diagnosis. As cancer reduced survival only in DM and IBM patients, these data support a strategy of limited cancer screening in IIM.PMID:38302176 | DOI:10.3899/jrheum.2023-1044 (Source: J Rheumatol)
Source: J Rheumatol - February 1, 2024 Category: Rheumatology Authors: Johannes Nossent Helen Keen David Preen Charles Inderjeeth Source Type: research
Cancer risk and mortality in hospitalised patients with idiopathic inflammatory myopathies in Western Australia
CONCLUSION: Cancer risk is not increased prior to IIM, but CIR for lung cancer is increased following DM diagnosis. As cancer reduced survival only in DM and IBM patients, these data support a strategy of limited cancer screening in IIM.PMID:38302176 | DOI:10.3899/jrheum.2023-1044 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 1, 2024 Category: Rheumatology Authors: Johannes Nossent Helen Keen David Preen Charles Inderjeeth Source Type: research
The spectrum of idiopathic inflammatory myopathies in Western Australia: epidemiological characteristics and mortality over time
AbstractTo determine long term overall and subgroup specific incidence rates and associated mortality for idiopathic inflammatory myopathies (IIM) in a population wide study. We included patients hospitalised between 1980 and 2015 with incident IIM as defined by relevant diagnostic codes for dermatomyositis (DM) polymyositis (PM), inclusion body myositis (IBM), other IIM and overlap myositis (OM) in the Western Australia Health Hospital Morbidity Data Collection (n = 846). Trends over time for annual incidence rate per million population (AIR) were analysed by least square regression and Kaplan–Meier survival and mor...
Source: Rheumatology International - January 20, 2024 Category: Rheumatology Source Type: research
ACR Image Competition 2023 Results, Part 2
For the 2023 Image Competition, the ACR sought images representing a diverse range of patients with idiopathic inflammatory myopathies (IIMs) or IIM mimics. These images won the Europe and Central Asia region. Glycogen Storage Disease Type V Diagnosed Using Imaging, Biopsy & Genetic Testing These images depict a 55-year-old patient with suspected polymyositis who presented... (Source: The Rheumatologist)
Source: The Rheumatologist - January 10, 2024 Category: Rheumatology Authors: Marco Fornaro, MD Tags: Conditions Myositis Other Rheumatic Conditions glycogen storage disease type V image case report Image Competition McArdle Disease Source Type: research
Increased Rate of Complications Following Total Knee Arthroplasty in Patients Who Have Polymyositis
Polymyositis (PM) is a systemic connective tissue disorder that can lead to early onset degenerative joint disease and a need for total knee arthroplasty (TKA). Outcomes of TKA in patients who have PM are not well-documented in the literature. The purpose of this study was to evaluate PM as a risk factor for complications after TKA. (Source: The Journal of Arthroplasty)
Source: The Journal of Arthroplasty - January 9, 2024 Category: Orthopaedics Authors: Elizabeth Driskill, Zhichang Zhang, Jialun Chi, Quanjun Cui Source Type: research
Clinicopathological Reclassification of Idiopathic Inflammatory Myopathy to Match the Serological Results of Myositis-Specific Antibodies
CONCLUSIONS: This new clinicopathological classification for IIM in combination with serological test results could be applied to our previous case series. Adoption of the new criteria will lead to a better understanding of the disease and hence new therapeutic insights.PMID:38179634 | DOI:10.3988/jcn.2022.0432 (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Young-Eun Park Dae-Seong Kim Minsung Kang Jin-Hong Shin Source Type: research
Clinicopathological Reclassification of Idiopathic Inflammatory Myopathy to Match the Serological Results of Myositis-Specific Antibodies
CONCLUSIONS: This new clinicopathological classification for IIM in combination with serological test results could be applied to our previous case series. Adoption of the new criteria will lead to a better understanding of the disease and hence new therapeutic insights.PMID:38179634 | PMC:PMC10782087 | DOI:10.3988/jcn.2022.0432 (Source: Journal of Clinical Neurology)
Source: Journal of Clinical Neurology - January 5, 2024 Category: Neurology Authors: Young-Eun Park Dae-Seong Kim Minsung Kang Jin-Hong Shin Source Type: research
Prognostic role of interferon ‐lambda 3 in anti‐MDA5–positive dermatomyositis‐associated ILD
ConclusionSerum IFN- λ3 is a promising biomarker for identifying patients at high risk of poor outcomes in anti-MDA5 antibody-positive DM-ILD.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatology)
Source: Arthritis and Rheumatology - December 26, 2023 Category: Rheumatology Authors: Atsuki Fukada,
Tomoyuki Fujisawa,
Hironao Hozumi,
Keigo Koda,
Taisuke Akamatsu,
Yoshiyuki Oyama,
Yasuomi Satake,
Mitsuru Niwa,
Yusuke Kaida,
Hiroyuki Matsuda,
Koshi Yokomura,
Naoki Koshimizu,
Mikio Toyoshima,
Shiro Imokawa,
Dai Hashimoto,
A Tags: Full Length Source Type: research
Anti-EJ antibody-positive interstitial pneumonia with breast cancer improved by combining immunosuppressive therapy and chemotherapy
We present a case of a 45-year-old woman diagnosed with interstitial pneumonia (IP) during a comprehensive breast cancer evaluation. Although the patient showed no obvious clinical symptoms of polymyositis or dermatomyositis, the presence of anti-glycyl-transfer ribonucleic acid synthetase antibodies confirmed anti-synthetase syndrome. The patient began methylprednisolone for treatment of the IP. She then received preoperative chemotherapy with epirubicin and cyclophosphamide before undergoing a mastectomy. A significant improvement was seen in the patient's IP during treatment. This case emphasizes the potential advantage...
Source: Respiratory Care - December 21, 2023 Category: Respiratory Medicine Authors: Ai Koike Masako Arimura-Omori Shuyo Umeda Akihisa Takano Yasuyuki Kishikawa Satoshi Nakamura Yuriko Takahata Yuki Okamatsu Akitaka Fujita Taishi Harada Source Type: research
