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Association of participants who screened positive for night eating syndrome with physical health, sleep problems, and weight status in an Australian adult population
CONCLUSIONS: Several physical health problems were found to be significantly associated with the spNES group including sleep problems, increased BMI, increased levels of pain and lower self-reported physical health-related quality of life. Consequently, future research exploring the complex interaction between NES and these medical conditions may provide further insight into the diagnosis, screening tools and management of NES. Additionally, this study highlights the need for future studies which use larger population-based samples.LEVEL OF EVIDENCE: Level III. Evidence obtained from well-designed cohort or case-control an...
Source: Eating and weight disorders : EWD - September 20, 2023 Category: Eating Disorders & Weight Management Authors: Sai Janani Sakthivel Phillipa Hay Stephen Touyz David Currow Haider Mannan Source Type: research

Silver Nanoparticles as an Intracanal Medicament: A Scoping Review
ScientificWorldJournal. 2023 Sep 11;2023:9451685. doi: 10.1155/2023/9451685. eCollection 2023.ABSTRACTSilver nanoparticles (AgNPs) release Ag ions with potent bactericidal and anti-inflammatory effects. They have shown promising results as an intracanal medicament for removing Enterococcus faecalis (E. faecalis), a resistant bacterium associated with root canal failures. This review summarizes the role of AgNPs as an intracanal medicament. Original research articles on AgNPs as an intracanal medicament were searched in databases such as MEDLINE (PubMed), Scopus, and Embase, resulting in 24 studies. They showed that AgNPs e...
Source: The Scientific World Journal - September 20, 2023 Category: Science Authors: Azra Kaukab Sumit Gaur Rupali Agnihotri Vani Taneja Source Type: research

Cervical laminoplasty versus laminectomy and posterior cervical fusion for cervical myelopathy: propensity-matched analysis of 24-month outcomes from the Quality Outcomes Database
CONCLUSIONS: Compared with PCF, laminoplasty was associated with decreased blood loss, decreased length of hospitalization, and higher rates of home discharge. At 3 months, laminoplasty was associated with a higher rate of return to baseline activities. At 24 months, laminoplasty was associated with greater improvements in neck disability. Otherwise, laminoplasty and PCF shared similar outcomes for functional status, pain, quality of life, and satisfaction. Laminoplasty and PCF achieved similar neck pain scores, suggesting that moderate preoperative neck pain may not necessarily be a contraindication for laminoplasty.PMID:...
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Eunice Yang Praveen V Mummaneni Dean Chou Mohamad Bydon Erica F Bisson Christopher I Shaffrey Oren N Gottfried Anthony L Asher Domagoj Coric Eric A Potts Kevin T Foley Michael Y Wang Kai-Ming Fu Michael S Virk John J Knightly Scott Meyer Paul Park Cheerag Source Type: research

Optimizing surgical management of facet cysts of the lumbar spine: systematic review, meta-analysis, and local case series of 1251 patients
CONCLUSIONS: While PCR is less invasive, it may have high rates of same-level recurrence and revision surgery. Recurrence and revision rates for modalities such as ECR were not significantly different from those of OCR. While concomitant arthrodesis is more invasive, it might lead to lower recurrence rates and lower rates of subsequent revision surgery. Given the limitations of our case series and literature review, prospective, randomized studies are needed.PMID:37728373 | DOI:10.3171/2023.6.SPINE23404
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Arjun Ganga Owen P Leary Aayush Setty Kevin Xi Albert E Telfeian Adetokunbo A Oyelese Tianyi Niu Joaquin Q Camara-Quintana Ziya L Gokaslan Patricia Zadnik Sullivan Jared S Fridley Source Type: research

Economic burden of nonoperative treatment of adult spinal deformity
CONCLUSIONS: Patients with ASD undergoing operative treatment at baseline had greater sagittal deformity and greater improvement in health-related quality of life postoperatively compared to patients treated nonoperatively. Additionally, patients in the nonoperative cohort overall had an increase in ODI and did not show improvement in utility gained. Patients in the nonoperative cohort who had low disability and sagittal deformity underwent successful maintenance and cost-effective treatment.PMID:37728175 | DOI:10.3171/2023.7.SPINE23195
Source: Journal of Neurosurgery.Spine - September 20, 2023 Category: Neurosurgery Authors: Peter G Passias Waleed Ahmad Pooja Dave Renaud Lafage Virginie Lafage Jamshaid Mir Eric O Klineberg Khaled M Kabeish Jeffrey L Gum Breton G Line Robert Hart Douglas Burton Justin S Smith Christopher P Ames Christopher I Shaffrey Frank Schwab Richard Hosti Source Type: research

Moderately severe acute pancreatitis after snake bite: a case report from Southern China
In this report, we presented a rare case of moderately severe acute pancreatitis caused by snake venom even after prompt antivenom treatment. The patient was relieved, obviously, with effective treatment of acute pancreatitis and was discharged without severe complications. Although acute pancreatitis after snake bite is a rarity, its serious complications and lethality still deserve our utmost attention, and timely and standardized treatment of acute pancreatitis is needed in addition to antivenom treatment.PMID:37729941 | DOI:10.1055/a-2150-2291
Source: Zeitschrift fur Gastroenterologie - September 20, 2023 Category: Gastroenterology Authors: Ronglai Cao Jinli He Zhengping Yu Youxiang Chen Liang Zhu Source Type: research

49-year-old woman • headache and neck pain radiating to ears and eyes • severe hypertension • Dx?
J Fam Pract. 2023 Sep;72(7):E26-E29. doi: 10.12788/jfp.0659.ABSTRACT► headache and neck pain radiating to ears and eyes ► severe hypertension.PMID:37729146 | DOI:10.12788/jfp.0659
Source: The Journal of Family Practice - September 20, 2023 Category: Practice Management Authors: Christian Saleh Muhannad Seyam Kristine A Blackham Anna Walter Philippe Lyrer Source Type: research

Is low-dose naltrexone effective in chronic pain management?
J Fam Pract. 2023 Sep;72(7):320-321. doi: 10.12788/jfp.0654.ABSTRACTYES. Low-dose naltrexone is as effective as amitriptyline in the treatment of painful diabetic neuropathy and has a superior safety profile (strength of recommendation [SOR], B; single randomized controlled trial [RCT]). Low-dose naltrexone significantly reduced pain by 32% in inflammatory conditions and 44% in neuropathic conditions (SOR, B; single retrospective cohort study). Doses as low as 5.4 mg were found to reduce pain in 95% of patients with fibromyalgia (SOR, B; single prospective dose-response study).PMID:37729143 | DOI:10.12788/jfp.0654
Source: The Journal of Family Practice - September 20, 2023 Category: Practice Management Authors: Roxanne Radi Harriet Huang Jason Rivera Corey Lyon Kristen DeSanto Source Type: research

The composition, pharmacological effects, related mechanisms and drug delivery of alkaloids from Corydalis yanhusuo
Biomed Pharmacother. 2023 Sep 18;167:115511. doi: 10.1016/j.biopha.2023.115511. Online ahead of print.ABSTRACTCorydalis yanhusuo W. T. Wang, also known as yanhusuo, yuanhu, yanhu and xuanhu, is one of the herb components of many Chinese Traditional Medicine prescriptions such as Jin Ling Zi San and Yuanhu-Zhitong priscription. C. yanhusuo was traditionally used to relieve pain and motivate blood and Qi circulation. Now there has been growing interest in pharmacological effects of alkaloids, the main bioactive components of C. yanhusuo. Eighty-four alkaloids isolated from C. yanhusuo are its important bioactive components a...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 20, 2023 Category: Drugs & Pharmacology Authors: Jia-Hua Feng Kang Chen Si-Yu Shen Yun-Feng Luo Xi-Hong Liu Xin Chen Wei Gao Yu-Ru Tong Source Type: research

Sigma-1 receptor agonism exacerbates immune-driven nociception: Role of TRPV1  + nociceptors
Biomed Pharmacother. 2023 Sep 18;167:115534. doi: 10.1016/j.biopha.2023.115534. Online ahead of print.ABSTRACTThe analgesic effects of sigma-1 antagonists are undisputed, but the effects of sigma-1 agonists on pain are not well studied. Here, we used a mouse model to show that the administration of the sigma-1 agonists dextromethorphan (a widely used antitussive drug), PRE-084 (a standard sigma-1 ligand), and pridopidine (a selective drug being investigated in clinical trials for the treatment of neurodegenerative diseases) enhances PGE2-induced mechanical hyperalgesia. Superficial plantar incision induced transient weight...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 20, 2023 Category: Drugs & Pharmacology Authors: M Carmen Ruiz-Cantero Miguel Á Huerta Miguel Á Tejada Miriam Santos-Caballero Eduardo Fern ández-Segura Francisco J Ca ñizares Jos é M Entrena Jos é M Baeyens Enrique J Cobos Source Type: research

Effect of transversus abdominis plane block on postoperative outcomes in gynecologic oncology patients managed on an Enhanced Recovery After Surgery pathway
CONCLUSIONS: Surgeon-administered TAP blocks were associated with decreased length of stay and post-operative opioid use in patients not receiving scheduled NSAIDs. This decrease in opioid use was not associated with any increase in average or maximum pain scores.PMID:37729808 | DOI:10.1016/j.ygyno.2023.09.003
Source: Gynecologic Oncology - September 20, 2023 Category: Cancer & Oncology Authors: Kristin A Black Gregg Nelson Natalie Goucher Joshua Foley Sophia Pin Michael Chong Sunita Ghosh Steven P Bisch Source Type: research

CAM procedures in pain therapy: an evidence-based discourse is needed
Schmerz. 2023 Oct;37(5):378-388. doi: 10.1007/s00482-023-00759-w. Epub 2023 Sep 20.NO ABSTRACTPMID:37728710 | DOI:10.1007/s00482-023-00759-w
Source: Schmerz - September 20, 2023 Category: Anesthesiology Authors: Jutta H übner Christian Keinki Jens B üntzel Source Type: research

Scientific shortcomings in the CME article on complementary medicine in pain therapy
Schmerz. 2023 Oct;37(5):372-377. doi: 10.1007/s00482-023-00758-x. Epub 2023 Sep 20.NO ABSTRACTPMID:37728709 | DOI:10.1007/s00482-023-00758-x
Source: Schmerz - September 20, 2023 Category: Anesthesiology Authors: Dominik Irnich Petra B äumler Florian Bei ßner Jens Broscheit Holger Cramer Johannes Fleckenstein Kristin Kieselbach Jost Langhorst Harald Lucius Andreas Michalsen Georg Seifert Taras Usichenko Source Type: research

Relevance of complementary treatment options in pain therapy
Schmerz. 2023 Oct;37(5):314-318. doi: 10.1007/s00482-023-00750-5. Epub 2023 Sep 20.NO ABSTRACTPMID:37728708 | DOI:10.1007/s00482-023-00750-5
Source: Schmerz - September 20, 2023 Category: Anesthesiology Authors: Stefanie Liv Jahn Marc Werner Jens Broscheit Source Type: research

Deep Learning: Orthopaedic Research Evolves for the Future
The practice of hip and knee arthroplasty has morphed since the turn of the century, as arthroplasty surgeons have been eager to adopt new technologies in attempts to continuously improve care. For example, in the year 2000, primary arthroplasty patients were routinely staying 5 to 7 days in the hospital [1] and requiring long-acting narcotics [2]. Today, patients are routinely discharged on the same day with well-controlled pain and even more frail patients only stay overnight. Of course, there is still room for improvement.
Source: The Journal of Arthroplasty - September 20, 2023 Category: Orthopaedics Authors: Michael J. Taunton, Steve S. Liu, Michael A. Mont Tags: Editorial Source Type: research