In Small Study, CAR-T Therapy Pushes Lupus Into Remission
THURSDAY, Sept. 15, 2022 -- While there’s no cure for lupus and treatments don’t work for many of the 1.5 million people who live with the disease in the United States, a new study shows a cancer therapy may kick hard-to-treat lupus into... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 15, 2022 Category: General Medicine Source Type: news
Cell-killing cancer therapy shows promise for a devastating autoimmune disorder
Opening a new frontier in fighting autoimmune disease, researchers have successfully treated five lupus patients with a novel cell therapy that turns run-of-the-mill immune cells into specialized hunters of rogue cells helping fuel illness. The patients treated with the new therapy all saw their severe symptoms, including kidney and other organ dysfunction, largely disappear.
The results “are phenomenal,” says Betty Diamond, an immunologist and rheumatologist at the Feinstein Institutes for Medical Research who cares for lupus patients and was not involved in the work. Despite her excitement, she cautions that th...
Source: ScienceNOW - September 15, 2022 Category: Science Source Type: news
Scientists hail autoimmune disease therapy breakthrough
Study finds CAR T-cell treatment sends lupus into remission, raising hopes it could be used to treat diseases such multiple sclerosisFive people with severe autoimmune disease have become the first in the world to receive a groundbreaking therapy that uses genetically altered cells to drive the illness into remission.The four women and one man, aged 18 to 24, received transfusions of modified immune cells to treat severe lupus, an autoimmune disease that can cause life-threatening damage to the heart, lungs, brain and kidneys.Continue reading... (Source: Guardian Unlimited Science)
Source: Guardian Unlimited Science - September 15, 2022 Category: Science Authors: Ian Sample Science editor Tags: Science Health Genetics Multiple sclerosis Source Type: news
Is Cancer Therapy Also a Lupus Cure?
(MedPage Today) -- Autologous chimeric antigen receptor T-cell (CAR-T) therapy, an approach that has taken the oncology world by storm in recent years, could also revolutionize treatment for systemic lupus erythematosus (SLE), preliminary results... (Source: MedPage Today Hematology/Oncology)
Source: MedPage Today Hematology/Oncology - September 15, 2022 Category: Hematology Source Type: news
Lupus, Psoriasis Patients May Face Greater Dangers After Heart Attack
THURSDAY, Sept. 15, 2022 -- People with autoimmune disorders like lupus, rheumatoid arthritis or psoriasis who suffer a heart attack are more likely to die or develop severe heart-related complications in the aftermath, a new study shows.
A heart... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 15, 2022 Category: General Medicine Source Type: news
Low Sleep Tied to Lupus Risk
(MedPage Today) -- Women's risk of new-onset systemic lupus erythematosus (SLE) was linked to habitually getting less-than-recommended sleep, according to Nurses Health Study (NHS) data, although an actual causal relationship remained uncertain... (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - September 13, 2022 Category: Primary Care Source Type: news
Litifilimab Meets Primary Endpoint in Phase 2 Lupus Trial Litifilimab Meets Primary Endpoint in Phase 2 Lupus Trial
Treatment group saw greater reduction in number of tender and swollen joints.Medscape Medical News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - September 13, 2022 Category: Dermatology Tags: Rheumatology News Source Type: news
Novel Study Offers Clues to Sex Bias in Lupus Incidence Novel Study Offers Clues to Sex Bias in Lupus Incidence
Researchers compared immune cells in cisgender and transgender subjects to investigate the role of sex hormones independently from chromosomes in a study on sex bias in autoimmune disease.MDedge News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - September 12, 2022 Category: Dermatology Tags: Rheumatology News Source Type: news
Reduction in Swollen, Tender Joints Greater With Litifilimab in Lupus
THURSDAY, Sept. 8, 2022 -- Patients with systemic lupus erythematosus (SLE) receiving litifilimab, a humanized monoclonal antibody that binds to blood dendritic cell antigen 2, versus placebo have a greater reduction in the number of swollen and... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - September 8, 2022 Category: Pharmaceuticals Source Type: news
Experimental Drug Shows Promise Against Lupus
THURSDAY, Sept. 8, 2022 -- An experimental drug that has been shown to treat rashes in people with lupus may also help with lupus-related joint pain.
Affecting as many as 1.5 million people in the United States, lupus is an autoimmune disease in... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 8, 2022 Category: General Medicine Source Type: news
Mixed Results for Novel Lupus Drug in Mid-Stage Trial
(MedPage Today) -- An investigational biologic agent with an entirely new mechanism of action appeared effective for limiting joint involvement in systemic lupus erythematosus (SLE), results from a phase II randomized trial indicated.
Lupus patients... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 8, 2022 Category: Rheumatology Source Type: news
Lupus, MS and Other Autoimmune Disorders Raise Heart Risks
WEDNESDAY, Aug. 31, 2022 -- Research has linked heart disease to specific autoimmune diseases such as rheumatoid arthritis and lupus. Now, a huge study shows that autoimmune diseases as a group increase your chances of developing heart... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 31, 2022 Category: General Medicine Source Type: news
Pill to Counter Lupus Shows Promise in Mouse Study
THURSDAY, Aug. 25, 2022 -- An experimental new pill could boost treatment of the autoimmune disease lupus, researchers reported at the American Chemical Society ' s annual meeting.
The pill has been shown in mouse studies to inhibit lupus symptoms,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 25, 2022 Category: General Medicine Source Type: news
Pill to Counter Lupus Shows Promise in Mouse Study
Title: Pill to Counter Lupus Shows Promise in Mouse StudyCategory: Health NewsCreated: 8/25/2022 12:00:00 AMLast Editorial Review: 8/25/2022 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - August 25, 2022 Category: Rheumatology Source Type: news
What Caused This Summer Birthday Party Rash?
Discussion
Panniculitides are a diverse group of problems involving inflammation of subcutaneous fat. Subcutaneous fat has limited ability to show different patterns of disease and therefore the clinical appearance is the same but has different etiologies. The skin appears red or purple, swollen, may have discrete nodule(s) or plaque(s) and the affected area can be painful or pruritic. If necessary skin biopsy can help determine the etiology. Overall panniculitides are not very common but some presentations are expected because of particular exposure (i.e. cold) or inflammatory disease processes.
Types of panniculitides in...
Source: PediatricEducation.org - August 22, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
