Alkermes' Sleeping Disorder Studies' Data Look Excellent, Analyst Says
On Tuesday, Alkermes plc ALKS revealed topline results from the narcolepsy type 2 (NT2) and idiopathic hypersomnia (IH) cohorts of a phase 1b, proof-of-concept study evaluating ALKS 2680 for narcolepsy. ALKS 2680 data demonstrated clinically meaningful and statistically significant improvements…#alkermesplcalks #alks2680 #mwt #alks #placebo #ih #jefferies #alkermesalks2680 (Source: Reuters: Health)
Source: Reuters: Health - April 9, 2024 Category: Consumer Health News Source Type: news

How to tell if you have the sleep disorder that even doctors don't know about
Do you struggle to get out of bed without an alarm clock, then feel tired all day? You might assume this is caused by lack of sleep, yet for some people it can be a sign of idiopathic hypersomnia. (Source: the Mail online | Health)
Source: the Mail online | Health - April 9, 2024 Category: Consumer Health News Source Type: news

Wake up tired after hours of rest? You may have a sleep disorder that even doctors don't know about
Do you struggle to get out of bed without an alarm clock, then feel tired all day? You might assume this is caused by lack of sleep, yet for some people it can be a sign of idiopathic hypersomnia. (Source: the Mail online | Health)
Source: the Mail online | Health - April 9, 2024 Category: Consumer Health News Source Type: news

Zevra Therapeutics Announces Top-Line Data from the Phase 2 Clinical Trial of KP1077 for Idiopathic Hypersomnia
Top-line data provide key information for the design of a Phase 3 study CELEBRATION, Fla., March 26, 2024 (GLOBE NEWSWIRE) -- Zevra Therapeutics, Inc. ZVRA (Zevra, or the Company) a rare disease therapeutics company, today announced top-line data from its placebo-controlled, double-blind Phase 2…#celebration #fla #zevra #phase2 #nct05668754 #kp1077 #zevraphase2 #ih #christopherdrake #phd (Source: Reuters: Health)
Source: Reuters: Health - March 26, 2024 Category: Consumer Health News Source Type: news

Axsome Therapeutics Announces Results of CRESCENDO Narcolepsy Patient Survey Demonstrating Unmet Needs in Treated Narcolepsy Type 1 Patients
77% of narcolepsy type 1 patients continue to experience cataplexy attacks despite being treated 64% of narcolepsy type 1 patients continue to experience excessive daytime sleepiness, as assessed by the Epworth Sleepiness Scale (ESS), despite being treated 74% of treated narcolepsy type 1 patients…#bccci #depression #cns #unmetneeds #narcolepsy #narcolepsynetwork #hypersomnia #crescendo #nt1 #eds (Source: Reuters: Health)
Source: Reuters: Health - March 25, 2024 Category: Consumer Health News Source Type: news

Street Calls of the Week: Compass downgrade
Investing.com -- Here is your Pro Recap of the top takeaways from Wall Street analysts for the past week: upgrade for Coty, downgrades for Alkermes, and Boeing. InvestingPro subscribers always get first dibs on market-moving rating changes. What happened? On Tuesday, UBS downgraded Alkermes…#coty #boeing #investingpro #ubs #sell #alks #phase1 #lybalvi #hypersomnia #fsr (Source: Reuters: Health)
Source: Reuters: Health - February 25, 2024 Category: Consumer Health News Source Type: news

Reported history of childhood trauma, mentalizing deficits, and hypersomnia in adulthood: a mediational analysis in a nonclinical sample - Kalantar-Hormozi B, Mohammadkhani S.
This study focused on the relationship between childhood trauma and hypersomnia specifically, which is understudied. Additional... (Source: SafetyLit)
Source: SafetyLit - February 22, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Idiopathic hypersomnia with a video recording of a spontaneous sleep attack: a case report - Asaga T, Hashimoto K, Kawamura Y, Fujita N, Kimata M, Sekizawa A, Ono Y, Obuchi Y, Kobayashi N, Hirasawa H, Kanbayashi T, Tanaka Y.
RATIONALE: Although patients with central disorders of hypersomnolence (CDH) exhibit characteristic symptoms of hypersomnia frequently, it takes 5 to 15 years from the onset for its diagnosis due to the lack of symptom recognition. Here, we present a case ... (Source: SafetyLit)
Source: SafetyLit - February 19, 2024 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

When night falls fast: sleep and suicidal behavior among adolescents and young adults - Fernandes SN, Zuckerman E, Miranda R, Baroni A.
Sleep disturbances have been linked to suicidal ideation and behaviors in adolescents. Specifically, insomnia and nightmares are associated with current suicide risk and predict future ideation. Associations between hypersomnia, sleep apnea, and suicide re... (Source: SafetyLit)
Source: SafetyLit - February 5, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Estimated Prevalence of Idiopathic Hypersomnia 1.5 Percent
THURSDAY, Dec. 14, 2023 -- Idiopathic hypersomnia (IH) has an estimated prevalence of 1.5 percent, according to a study published online Dec. 13 in Neurology. David T. Plante, M.D., Ph.D., from the University of Wisconsin-Madison, and colleagues... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 14, 2023 Category: Pharmaceuticals Source Type: news

Nearly 5MILLION Americans have little-known sleep disorder that leaves people exhausted even after getting 8 hours of rest a night, scientists say
Researchers in the US estimated that as many as one in 70 individuals, or nearly 5million Americans, have 'idiopathic hypersomnia' - far more than previously thought. (Source: the Mail online | Health)
Source: the Mail online | Health - December 13, 2023 Category: Consumer Health News Source Type: news

Harriet Tubman's hypersomnia: insights from historical and medical perspectives - Balmuth EA, Scammell TE.
Harriet Tubman, a hero of the abolitionist movement and early civil rights advocate, suffered a head injury in childhood and subsequently developed sleep attacks associated with visions that were extensively documented in historical accounts. Her contempor... (Source: SafetyLit)
Source: SafetyLit - September 25, 2023 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news

Heart Risks Much Higher for Patients With Rare Sleep Disorder
(MedPage Today) -- NASHVILLE, Tenn. -- Individuals with idiopathic hypersomnia may face a greater likelihood of heart-related events, a retrospective cohort study suggested. Compared with matched controls without the rare sleep disorder, patients... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - September 11, 2023 Category: Cardiology Source Type: news

Suffering from long COVID? Here's how a new NIH study could help ease symptoms
The National Institutes of Health is calling on long COVID patients to participate in clinical trials evaluating multiple treatments that may finally ease symptoms for millions worldwide. The trials will include four potential treatments, will lead to additional trials in the coming months that…#nih #lawrenceatabak #kff #nonerecovervital #nonerecoverneuro #nonerecoversleep #hypersomnia #nonerecoverautonomic #noneexercise #kaneciazimmerman (Source: Reuters: Health)
Source: Reuters: Health - July 31, 2023 Category: Consumer Health News Source Type: news

Stimulating hypocretin receptors improves sleepiness and vigilance in idiopathic hypersomnia: lessons from a proof of concept study - Arnulf I, Maranci JB.
[Abstract unavailable] Language: en... (Source: SafetyLit)
Source: SafetyLit - May 22, 2023 Category: International Medicine & Public Health Tags: Commentary Source Type: news