New study sheds light on mysterious infant deaths nearly a century ago
A move to eradicate rickets by fortifying foods with Vitamin D preceded a wave of mysterious infant deaths in the 1930s and 1940s. Now scientists have a better answer as to why. A partial answer came in 2011, when researchers discovered a condition called infantile hypercalcaemia type 1, caused by…#unitedkingdom #darrellgreen #rna #norwichmedicalschool #green (Source: Reuters: Health)
Source: Reuters: Health - January 26, 2023 Category: Consumer Health News Source Type: news

Doctors warn over natural therapies after autistic boy left severely ill
Police investigated naturopath after mixtures left four-year-old vomiting and constipated for three weeks with dangerously high levels of calcium in his bloodDoctors from Barts hospital have warned of the dangers of alternative medicines after a four-year-old autistic boy was admitted to hospital suffering adverse effects from a cocktail of supplements.The child, who was not named in a report of the incident, had been vomiting and constipated for three weeks and also lost 3kg in weight before he was taken to accident and emergency and diagnosed with severe hypercalcaemia – or very high calcium levels in his blood.Continu...
Source: Guardian Unlimited Science - October 7, 2016 Category: Science Authors: Press Association Tags: Alternative medicine UK news Medical research Science Source Type: news

Simple blood test could be used as tool for early cancer diagnosis
High levels of calcium in blood, a condition known as hypercalcemia, can be used by GPs as an early indication of certain types of cancer, according to a study by researchers. Hypercalcaemia is the most common metabolic disorder associated with cancer, occurring in 10 to 20 per cent of people with cancer. While its connection to cancer is well known, this study has, for the first time, shown that often it can predate the diagnosis of cancer in primary care. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - September 25, 2014 Category: Science Source Type: news

Simple blood test could be used as tool for early cancer diagnosis
High levels of calcium in blood, a condition known as hypercalcaemia, can be used by GPs as an early indication of certain types of cancer, according to a study by researchers from the universities of Bristol and Exeter. (Source: University of Bristol news)
Source: University of Bristol news - September 25, 2014 Category: Universities & Medical Training Tags: Research; Faculty of Medicine and Dentistry, Faculty of Medicine and Dentistry, School of Social and Community Medicine; Press Release Source Type: news

An unusual complication of injecting paraffin oil to enhance body sculpting
3 out of 5 stars Severe hypercalcaemia, nephrocalcinosis, and multiple paraffinomas caused by paraffin oil injections in a young bodybuilder. Gyldenløve M et al. Lancet 2014 Jun14;383:2098 Reference This short case report describes a 23-year-old male bodybuilder who presented with scrotal pain. The patient also admitted to shortness of breath and chest tightness. Workup for infection and nephrolithiasis was negative. Laboratory tests revealed anemia, renal insufficiency, and severe hypercalcemia (free calcium approximately twice normal.) Physical examination revealed multiple dense nodules in the skin and subcutaneous t...
Source: The Poison Review - June 20, 2014 Category: Toxicology Authors: Leon Tags: Medical body building body sculpting calcium CYP27B1 hypercalcemia mineral oil paraffin oil vitamin D Source Type: news

Outcome prediction in primary hyperparathyroidism
For 30 years baseline serum calcium concentration has been the primary surgical selection criteria for patients with primary hyperparathyroidism (PHPT). Yu and colleagues have previously demonstrated that PHPT patients with mild hypercalcaemia are also at increased risk of adverse complications. They now go on to demonstrate that baseline parathyroid hormone at the time of diagnosis best predicts long-term outcomes in untreated PHPT. Read the full article in Yu et al (2013) Clinical Endocrinology 79; 27–34; DOI: 10.1111/cen.12206. (Source: Society for Endocrinology)
Source: Society for Endocrinology - July 15, 2013 Category: Endocrinology Source Type: news

Society for Endocrinology Emergency Endocrine Guidance
The Society for Endocrinology’s Clinical Committee has produced Emergency Endocrine Guidance for three potentially life-threatening conditions which would necessitate urgent treatment: Acute Hypercalcaemia, Acute Hypocalcaemia (in adults) and Pituitary Apoplexy. These documents are targeted at health professionals and the emergency services and aim to provide emergency guidance through the initial phase of assessment and management of the patient. These documents are available to download from the Society website http://www.endocrinology.org/policy/ and will be published for distribution in the near future. We...
Source: Society for Endocrinology - July 15, 2013 Category: Endocrinology Source Type: news