This page shows you your search results in order of date. This is page number 11.
Order by Relevance | Date
Total 221853 results found since Jan 2013.
Structural dynamics of chemokine receptors
Vitam Horm. 2023;123:645-662. doi: 10.1016/bs.vh.2023.05.005. Epub 2023 Jun 26.ABSTRACTMembrane proteins such as G protein-coupled receptors (GPCRs) are involved in awide range of physiological and pathological cellular processes. Binding of extracellular signals to GPCRs, including hormones, neurotransmitters, peptides and proteins, can activate intracellular signaling cascades via G protein interaction. Chemokine receptors are key GPCRs implicated in cancers, immune responses, cell migration and inflammation. Specifically, the CCR5 and CXCR4 chemokine receptors serve as important therapeutic targets against Human Immunod...
Source: Vitamins and Hormones - September 17, 2023 Category: Endocrinology Authors: Shristi Pawnikar Sana Akhter Yinglong Miao Source Type: research
Who lives and who dies in the next pandemic should not depend on where they live | Michael Marmot
Aids and Covid had the worst impact in poorer countries and communities; a new health accord must address thisThe Covid pandemic was an equivocator with global unity – to misquote the porter inMacbeth. We were united in being affected by the pandemic but both its effects and the responses to it were grossly unequal. More, inequality worsens pandemics, not only current pandemics such as Aids and Covid but those yet to come.Governments are looking to address one side of this equivocation through their negotiations on apandemic accord that will be discussed during the UN general assembly in New York this month. Such a devel...
Source: Guardian Unlimited Science - September 17, 2023 Category: Science Authors: Michael Marmot Tags: Health Inequality Coronavirus Aids and HIV Infectious diseases Medical research Society Source Type: news
Impact of very early antiretroviral therapy during acute HIV infection on long-term immunovirological outcomes
Acute HIV infection (AHI) refers to the period immediately after acquiring HIV, when the virus spreads first through the mucosa and the local lymphoid tissue at the exposure site, and then disseminates systemically [1,2]. This initial phase of HIV infection can be divided into stages based on the sequential appearance of viral markers and antibodies in the blood [3]. It is during AHI when the latent HIV reservoir is established [4], although reseeding of the reservoir will continue in untreated chronic infection [5].
Source: International Journal of Infectious Diseases - September 17, 2023 Category: Infectious Diseases Authors: Paula Suanzes, Jordi Navarro, Ariadna Rando-Segura, Patricia Álvarez-López, Jorge García, Vicente Descalzo, Arnau Monforte, Maider Arando, Lucía Rodríguez, Bibiana Planas, Joaquín Burgos, Adrian Curran, María José Buzón, Vicenç Falcó Source Type: research
Comparing typologies of violence exposure and associations with syndemic health outcomes among cisgender and transgender female sex workers living with HIV in the Dominican Republic - Maclin BJ, Wang Y, Rodr íguez-Díaz C, Donastorg Y, Perez M, Gomez H, Barrington C, Kerrigan D.
This study compares patterns of violence exposure among cisgender and transgender female sex workers (FSWs) and th...
Source: SafetyLit - September 16, 2023 Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
Prevention and elimination efforts of HIV/AIDS caused by sexual violence against women in the Democratic Republic of the Congo: an editorial - Ciswaka H, Oduoye MO, Masimango G, Bavurhe RF, Bulondo D, Biamba C, Kibukila F, Feza P, Akilimali A, Nyakio O.
[Abstract unavailable]
Language: en...
Source: SafetyLit - September 16, 2023 Category: International Medicine & Public Health Tags: Commentary Source Type: news
Prevalence and correlates of condom use at last sexual intercourse pre- and post-COVID-19 lockdown among adolescent girls and young women in central and western Kenya
Afr J Reprod Health. 2023 Jun;27(6):70-76. doi: 10.29063/ajrh2023/v27i6.8.ABSTRACTWe investigated condom use at last sexual intercourse among adolescent girls and young women (AGYW) to determine the prevalence and correlates of condom use pre- and post-COVID-19 lockdown. Condom use was compared pre- and post-COVID-19 lockdown using a single group interrupted time series analysis. Multivariable Poisson regression was used to determine the correlates of condom use at last sexual intercourse. We found a statistically significant decrease in prevalence of condom use at last sexual intercourse post-COVID-19 lockdown. Condom use...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Syovata Kimanthi Maricianah Onono George Otieno Ruanne V Barnabas Betty Njoroge Ouma Congo Charlene Biwott Nelly Mugo Elizabeth K Harrington Source Type: research
Intimate partner violence is associated with cytomegalovirus among young women in rural South Africa: An HPTN 068 analysis
Glob Public Health. 2023 Jan;18(1):2258962. doi: 10.1080/17441692.2023.2258962.ABSTRACTABSTRACTStressful life circumstances (e.g. violence and poverty) have been associated with elevated biomarkers, including C-reactive protein (CRP), cytomegalovirus (CMV), and herpes simplex virus type-1 (HSV-1), among older adults in high-income settings. Yet, it remains unknown whether these relationships exist among younger populations in resource-limited settings. We therefore utilised a cohort of 1,279 adolescent girls and young women (AGYW) from the HIV Prevention Trials Network 068 study in rural South Africa to examine the associa...
Source: Herpes - September 16, 2023 Category: Infectious Diseases Authors: Nicole K Kelly F Xavier G ómez-Olivé L Danielle Wagner Allison E Aiello Kathleen Kahn Audrey Pettifor Marie C D Stoner Source Type: research
Guided LGBTQ-affirmative internet cognitive-behavioral therapy for sexual minority youth's mental health: A randomized controlled trial of a minority stress treatment approach
CONCLUSIONS: LGBTQ-affirmative ICBT represents a feasible and acceptable treatment. Future research can identify more efficacious approaches and modalities for engaging LGBTQ youth, especially those living under stigmatizing conditions, who might benefit most.PMID:37716019 | DOI:10.1016/j.brat.2023.104403
Source: Behaviour Research and Therapy - September 16, 2023 Category: Psychiatry & Psychology Authors: John E Pachankis Zachary A Soulliard Eric K Layland Kriti Behari Ilana Seager van Dyk Benjamin E Eisenstadt Danielle Chiaramonte Brj ánn Ljótsson Josefin S ärnholm Johan Bjureberg Source Type: research
Intimate partner violence is associated with cytomegalovirus among young women in rural South Africa: An HPTN 068 analysis
Glob Public Health. 2023 Jan;18(1):2258962. doi: 10.1080/17441692.2023.2258962.ABSTRACTABSTRACTStressful life circumstances (e.g. violence and poverty) have been associated with elevated biomarkers, including C-reactive protein (CRP), cytomegalovirus (CMV), and herpes simplex virus type-1 (HSV-1), among older adults in high-income settings. Yet, it remains unknown whether these relationships exist among younger populations in resource-limited settings. We therefore utilised a cohort of 1,279 adolescent girls and young women (AGYW) from the HIV Prevention Trials Network 068 study in rural South Africa to examine the associa...
Source: Herpes - September 16, 2023 Category: Infectious Diseases Authors: Nicole K Kelly F Xavier G ómez-Olivé L Danielle Wagner Allison E Aiello Kathleen Kahn Audrey Pettifor Marie C D Stoner Source Type: research
Prevalence and correlates of condom use at last sexual intercourse pre- and post-COVID-19 lockdown among adolescent girls and young women in central and western Kenya
Afr J Reprod Health. 2023 Jun;27(6):70-76. doi: 10.29063/ajrh2023/v27i6.8.ABSTRACTWe investigated condom use at last sexual intercourse among adolescent girls and young women (AGYW) to determine the prevalence and correlates of condom use pre- and post-COVID-19 lockdown. Condom use was compared pre- and post-COVID-19 lockdown using a single group interrupted time series analysis. Multivariable Poisson regression was used to determine the correlates of condom use at last sexual intercourse. We found a statistically significant decrease in prevalence of condom use at last sexual intercourse post-COVID-19 lockdown. Condom use...
Source: African Journal of Reproductive Health - September 16, 2023 Category: African Health Authors: Syovata Kimanthi Maricianah Onono George Otieno Ruanne V Barnabas Betty Njoroge Ouma Congo Charlene Biwott Nelly Mugo Elizabeth K Harrington Source Type: research
Decoding the invasive nature of a tropical pathogen of concern: The invasive non-Typhoidal Salmonella strains causing host-restricted extraintestinal infections worldwide
Microbiol Res. 2023 Sep 12;277:127488. doi: 10.1016/j.micres.2023.127488. Online ahead of print.ABSTRACTInvasive-Non-Typhoidal Salmonella (iNTS) are the major cause of health concern in the low-income, under-developed nations in Africa and Asia that lack proper sanitation facilities. Around 5% of the NTS cases give rise to invasive, extraintestinal diseases leading to focal infections like osteomyelitis, meningitis, osteoarthritis, endocarditis and neonatal sepsis. iNTS serovars like S. Typhimurium, S. Enteritidis, S. Dublin, S. Choleraesuis show a greater propensity to become invasive than others which hints at the geneti...
Source: Cell Research - September 16, 2023 Category: Cytology Authors: Dipasree Hajra Abhilash Vijay Nair Dipshikha Chakravortty Source Type: research
