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Polypharmacy and Potential Drug-Drug Interactions for HIV Polypharmacy and Potential Drug-Drug Interactions for HIV
Are you aware of the types of concurrent medications commonly prescribed to HIV patients and the potential drug-drug interactions?HIV Medicine
Source: Medscape Hiv-Aids Headlines - October 9, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Inappropriate Medications in Older Adults With HIV Inappropriate Medications in Older Adults With HIV
Prescribing potentially inappropriate medications to older individuals with HIV could have serious consequences. Which strategies could prevent unnecessary polypharmacy?HIV Medicine
Source: Medscape Hiv-Aids Headlines - October 2, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Comorbidity Indices in People With HIV and COVID-19 Outcomes Comorbidity Indices in People With HIV and COVID-19 Outcomes
Do comorbidities in people living with HIV place them at a higher risk for poorer COVID-19 outcomes?AIDS
Source: Medscape Hiv-Aids Headlines - September 25, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Risks, Characteristics and Outcomes by Age at HIV Diagnosis Risks, Characteristics and Outcomes by Age at HIV Diagnosis
What have we learned about the clinical features and outcomes of older individuals newly diagnosed with HIV?HIV Medicine
Source: Medscape Hiv-Aids Headlines - September 25, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Molecular and genetic characterization of natural variants of HIV-1 Nef gene from North India and its functional implication in down-regulation of MHC-I and CD-4.
CONCLUSION: We observed enhanced biological activities in some of the variants, perhaps arising out of amino acid substitutions in their functional domains. The CD4 and MHC-1 down-regulation activity of Nef is likely to confer immense survival advantage allowing the most rare genotype in a population to become the most abundant after a single selection event. PMID: 32981506 [PubMed - as supplied by publisher]
Source: Current HIV Research - September 24, 2020 Category: Infectious Diseases Authors: Singh J, Ronsard L, Pandey M, Kapoor R, Ramachandran VG, Banerjea AC Tags: Curr HIV Res Source Type: research

Multidrug Resistance Common in Hospitalized Adults With HIV in Malawi Multidrug Resistance Common in Hospitalized Adults With HIV in Malawi
HIV-1 multidrug resistance is common and is associated with increased mortality among adults hospitalized with HIV infection in Malawi, according to a new study.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - September 18, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

Rate of Dyslipidemia Higher Among Women Living With HIV Rate of Dyslipidemia Higher Among Women Living With HIV
A new study provides insight into the prevalence of dyslipidemia among women with HIV.HIV Medicine
Source: Medscape Hiv-Aids Headlines - September 18, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Growing Old With HIV: Beyond Just Surviving Growing Old With HIV: Beyond Just Surviving
The aging of the population with HIV is a medical achievement to celebrate, but with this success comes a new conundrum.Medscape HIV/AIDS
Source: Medscape Hiv-Aids Headlines - September 17, 2020 Category: Infectious Diseases Tags: HIV/AIDS Commentary Source Type: news

Association Between Nonalcoholic Fatty Liver Disease and Bone Mineral Density in HIV-Infected Patients Receiving Long-Term TDF-Based Antiretroviral Therapy.
CONCLUSION: Based on our results, NAFLD was significantly associated with a worse BMD status, including osteopenia and osteoporosis, in HIV patients after receiving long-term TDF-based ART. Furthermore, we may want to avoid using TDF for ART in HIV-infected patients with NAFLD. PMID: 32940183 [PubMed - as supplied by publisher]
Source: Current HIV Research - September 16, 2020 Category: Infectious Diseases Authors: Xu Z, He P, Xian J, Lu W, Shu J, Luo W, Gan C, Ke R, Xia J, Han Z, Huang M Tags: Curr HIV Res Source Type: research

One in 10 Gay and Bisexual Men May Share HIV PrEP Medications One in 10 Gay and Bisexual Men May Share HIV PrEP Medications
A small but significant proportion of gay and bisexual men with prescriptions for HIV pre-exposure prophylaxis (PrEP) have been sharing their medication with others, a new study finds.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - September 14, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

Sleep Disruption Tied to Energy Homeostasis Gene Variants in HIV Patients Sleep Disruption Tied to Energy Homeostasis Gene Variants in HIV Patients
Both waking during sleep and total sleep time are associated with single nucleotide polymorphisms (SNPs) in five genes associated with energy homeostasis, according to a study of patients with HIV/AIDS.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - September 14, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

A TNF block genotype may influence CMV retinitis in HIV patients without affecting systemic viral replication.
Conclusion: The TNFA-308*A/BAT1(intron 10)*C haplotype appears to affect CMV-induced pathology rather than CMV replication. PMID: 32914715 [PubMed - as supplied by publisher]
Source: Current HIV Research - September 9, 2020 Category: Infectious Diseases Authors: Price P, Edwar L, Ha P, Ariyanto IA, Lee S, Estiasari R, Sitompul R Tags: Curr HIV Res Source Type: research

MicroRNAs Profiling in HIV, HCV and HIV/HCV Coinfected Patients.
CONCLUSION: These miRNAs are probably involved in the clinical progression and pathogenesis of HIV and HCV infections. Therefore, determining and manipulating of these miRNAs can lead to opening a new gate to control of these important infections. PMID: 32900348 [PubMed - as supplied by publisher]
Source: Current HIV Research - September 7, 2020 Category: Infectious Diseases Authors: Moghoofei M, Najafipour S, Mostafaei S, Tavakoli A, Bokharaei-Salim F, Ghorbani S, Javanmard D, Ghaffari H, Monavari SH Tags: Curr HIV Res Source Type: research

PEP Completion, Condom Use, and Sexual Exposure to HIV PEP Completion, Condom Use, and Sexual Exposure to HIV
How likely are individuals who have been sexually exposed to HIV to adhere to and complete a PEP regimen?HIV Medicine
Source: Medscape Hiv-Aids Headlines - September 4, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Anti-toxoplasmic Immunoglobulin G Quantitation Correlates with Immunovirological Parameters of HIV-Infected Cameroonians.
Conclusion: In Cameroon, about half of PLHIV might be seropositive to anti-Toxo IgG, with decreasing immunity appearing as risk of toxoplasmosis relapse. Thus, in the context of immunodeficiency, routine quantification of anti-Toxo IgG would alleviate the programmatic burden of this opportunistic infection in RLS with generalized HIV epidemic. PMID: 32885755 [PubMed - as supplied by publisher]
Source: Current HIV Research - September 2, 2020 Category: Infectious Diseases Authors: Ka'e AC, Sosso SM, Fokam J, Simo RK, Essama SR, Nka AD, Yagai B, Dzukou CJN, Tchouaket MCT, Chenwi C, Abba A, Fainguem N, Zam MKN, Yimga JF, Colizzi V, Ndjolo A Tags: Curr HIV Res Source Type: research

HIV Patients Don ' t Have Worse Outcome After MI With Cardiogenic Shock HIV Patients Don ' t Have Worse Outcome After MI With Cardiogenic Shock
Outcomes of myocardial infarction-cardiogenic shock (AMI-CS) in patients with HIV but without AIDS are no worse than in patients without HIV, according to new findings.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - August 31, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

Testing for Sero-Reversion in HIV-Exposed Uninfected Infants Testing for Sero-Reversion in HIV-Exposed Uninfected Infants
Delaying HIV serological screening among exposed but uninfected infants may help reduce the need for re-testing.HIV Medicine
Source: Medscape Hiv-Aids Headlines - August 28, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Hitting the sweet spot: exploiting HIV-1 glycan shield for induction of broadly neutralizing antibodies
Purpose of review The surface of the HIV-1 Env glycoprotein, the target of neutralizing antibodies, is extensively covered by N-linked glycans that create a glycan shield. Broadly neutralizing antibodies (bNAbs), the primary targets of HIV-1 vaccine design, have to negotiate this glycan shield. Here, we review the barriers and opportunities that the HIV-1 glycan shield presents for vaccine induction of bNAbs. Recent findings Glycan shields can impact the nature of the antibody response and influence the development of neutralization breadth in HIV-1 infections. The architecture of the glycan shield arising from glycan...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Advances in simian--human immunodeficiency viruses for nonhuman primate studies of HIV prevention and cure
Purpose of review Simian--human immunodeficiency viruses (SHIVs), chimeric viruses that encode HIV-1 Env within an SIV backbone, are key reagents for nonhuman primate studies of antibody-based vaccines, broadly neutralizing antibodies (bnAbs), and other Env-targeting reagents. Here, we discuss the provenance and characteristics of currently relevant SHIVs, novel technical advances, recent discoveries enabled by SHIV challenge studies, and the continued development of SHIVs for persistence and cure experiments. Recent findings SHIV SF162P3, SHIV AD8EO, and transmitter/founder SHIVs with Env375 mutations are now common ...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Recent insights into Fc-mediated effector responses to HIV-1
Purpose of review Recent work defining Fc-mediated effector functions for both viral control and protection against infection is summarized and considered along with new strategies to drive robust Fc-mediated responses. Recent findings In new human and nonhuman primate (NHP) vaccine trials as well as studies of natural infection, Fc-mediated effector responses have sometimes been observed to correlate with decreased risk of infection or with better clinical outcomes, suggesting a potential role for these responses in HIV-1 prevention and therapy. Recent highlights include use of antibody-dependent cellular cytotoxicit...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Engineering antibody-based molecules for HIV treatment and cure
Purpose of review Immunotherapy strategies alternative to current antiretroviral therapies will need to address viral diversity while increasing the immune system's ability to efficiently target the latent virus reservoir. Antibody-based molecules can be designed based on broadly neutralizing and non-neutralizing antibodies that target free virions and infected cells. These multispecific molecules, either by IgG-like or non-IgG-like in structure, aim to target several independent HIV-1 epitopes and/or engage effector cells to eliminate the replicating virus and infected cells. This detailed review is intended to stimulat...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Opening the HIV envelope: potential of CD4 mimics as multifunctional HIV entry inhibitors
Purpose of review Close to 2 million individuals globally become infected with HIV-1 each year and just over two-thirds will have access to life-prolonging antivirals. However, the rapid development of drug resistance creates challenges, such that generation of more effective therapies is not only warranted but a necessary endeavour. This review discusses a group of HIV-1 entry inhibitors known as CD4 mimics which exploit the highly conserved relationship between the HIV-1 envelope glycoprotein and the receptor, CD4. Recent findings We review the structure/function guided evolution of these inhibitors, vital mechanist...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Broadly neutralizing antibodies combined with latency-reversing agents or immune modulators as strategy for HIV-1 remission
Purpose of review Antiretroviral therapy (ART) is extremely effective in controlling HIV-1 infection; however, ART is not curative. Here, we review broadly neutralizing anti-HIV-1 antibodies (bNAbs) combined with latency-reversing agents (LRAs) or immune modulators as strategy for achieving long-term HIV-1 remission. Recent findings Clinical trials testing the effect of a single intervention such as a LRA ‘shock and kill’, immune modulator or bNAbs among HIV-1 infected individuals on long-term suppressive ART have not lead to long-term HIV-1 remission when ART is stopped. Novel combinations of interventions design...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Roles of fragment crystallizable-mediated effector functions in broadly neutralizing antibody activity against HIV
Purpose of review ‘Broadly neutralizing antibodies’ (bNAbs), are rare HIV-specific antibodies which exhibit the atypical ability to potently neutralize diverse viral isolates. While efforts to elicit bNAbs through vaccination have yet to succeed, recent years have seen remarkable preclinical and clinical advancements of passive immunization approaches targeting both HIV prevention and cure. We focus here on the potential to build upon this success by moving beyond neutralization to additionally harness the diverse effector functionalities available to antibodies via fragment crystallizable-effector (Fc) functions. R...
Source: Current Opinion in HIV and AIDS - August 28, 2020 Category: Infectious Diseases Tags: ANTIBODY STRATEGIES IN HIV PREVENTION AND CURE: Edited by Mattia Bonsignori and Marina Caskey Source Type: research

Chronic Marijuana Use Unlikely to Further Harm the Brain in HIV Chronic Marijuana Use Unlikely to Further Harm the Brain in HIV
HIV-positive individuals who regularly use marijuana likely face no additional brain inflammation or cognitive deficits, researchers say.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - August 27, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

Assessing changes in vitamin D over 48 weeks in treatment-na ïve HIV individuals starting lopinavir/ritonavir monotherapy.
CONCLUSION: Individuals treated with lopinavir/ritonavir monotherapy had significantly higher 25(OH)D after 48 weeks. Current tobacco users had significantly diminished CD4 cell count recovery after starting treatment, warranting further clinical investigation. PMID: 32860360 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 26, 2020 Category: Infectious Diseases Authors: Crutchley RD, Jacobs DM, Gathe J, Mayberry C, Bulayeva N, Rosenblatt KP, Garey KW Tags: Curr HIV Res Source Type: research

Prevalence of Asymptomatic Cryptococcal Antigenemia and Association with Follow-up risk of Cryptococcal Meningitis and Mortality among HIV Infected Patients in North West India - A Prospective Cohort Study.
CONCLUSION: Serum cryptococcal positivity is correlated with increased risk of Cryptococcal meningitis and mortality in PLHIV. We recommend the screening of asymptomatic PLHIV with CD4 ≤ 100/µL for serum cryptococcal antigen, so that pre-emptive treatment can be initiated to reduce morbidity and mortality. PMID: 32860359 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 26, 2020 Category: Infectious Diseases Authors: Bhati R, Sirohi P, Sejoo B, Kumar D, Bohra GK, Meena DS, Verma D, Midha NK Tags: Curr HIV Res Source Type: research

Real-Life Impact on Lipid Profile of a Switch from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in HIV-Infected Patients.
Conclusion: In patients who switch from tenofovir disoproxil fumarate to tenofovir alafenamide, lipid profile is altered, and may require initiation of lipid-lowering therapy. It seems necessary to monitor lipid parameters after this switch, despite the absence of an official recommendation. PMID: 32838719 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 22, 2020 Category: Infectious Diseases Authors: Lagoutte-Renosi J, Flammang M, Chirouze C, BeckWirth G, Bozon F, Brunel AS, Drobacheff-Thiebaut MC, Foltzer A, Hustache-Mathieu L, Kowalczyk J, Michel C, Davani S, Muret P Tags: Curr HIV Res Source Type: research

Presentation and Survival of HIV Patients Admitted to an ICU Presentation and Survival of HIV Patients Admitted to an ICU
What have we learned about the outcomes of HIV-infected patients admitted to the ICU?HIV Medicine
Source: Medscape Hiv-Aids Headlines - August 21, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

A review of current strategies towards the elimination of latent HIV-1 and subsequent HIV-1 cure.
CONCLUSION: Recent advances hold promise for the ultimate cure of HIV infection. A systems-level approach that fully recapitulate the dynamics and complexity of HIV-1 latency in vivo and applicable in human therapy is prudent for HIV eradication to be more feasible. Future studies aimed at achieving a prolonged HIV remission state are more likely to be successful if they focus on a combination strategy including the block and kill, and stem cell approaches. These strategies propose a functional cure with minimal toxicity for patients. We believe that the cure of HIV infection will be attained in the short term if a strateg...
Source: Current HIV Research - August 18, 2020 Category: Infectious Diseases Authors: Maina EK, Adan AA, Mureithi H, Muriuki J, Lwembe RM Tags: Curr HIV Res Source Type: research

An HIV-positive patient presenting with malignant bone tumor in left tibia treated with microwave ablation for limb salvage.
CONCLUSIONS: MWA is a feasible and effective surgical method for limb salvage operation, especially for the patient with poor immunological function, e.g. HIV infection. It might offer an innovative and distinctive therapeutic alternative for malignant bone tumors, while avoiding prosthesis replacement. PMID: 32814533 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 18, 2020 Category: Infectious Diseases Authors: Gao T, Dong C, Zhang M, Ding R, Yang Y, Yu Z Tags: Curr HIV Res Source Type: research

Healthcare Utilization, Unmet Service Needs, and Medication Adherence among People Living with HIV/AIDS.
CONCLUSION: The results of this study indicate that health promotion programming should focus not only on introducing new services at the community level, but also work to optimize the availability and awareness of current services. Furthermore, health promotion programs should focus on filling service coverage gaps and improving the facilitation of services. PMID: 32807058 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 16, 2020 Category: Infectious Diseases Authors: Zhang X, Oman RF, Larson TA, Christiansen EJ, Granner ML, Lu M, Yang Y Tags: Curr HIV Res Source Type: research

Association between Antiretroviral Treatment and Markers of Systemic Inflammation among HIV Patients in Ghana.
CONCLUSION: Although the relatively small sample size limits the scope of the study's findings, these results suggest that individuals on ART need to be screened periodically for the development of chronic conditions. This line of investigation has the potential to influence treatment and clinical guidelines that will improve the quality of care for HIV-infected patients. PMID: 32807057 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 16, 2020 Category: Infectious Diseases Authors: T Haile Z, Sarfo B, Bonney EY, Mensah EA, Deletsu S Tags: Curr HIV Res Source Type: research

Validation of the D:A:D CKD Risk Score in HIV Patients Validation of the D:A:D CKD Risk Score in HIV Patients
Is the D:A:D risk scoring method a valid means of assessing CKD risk among HIV-infected patients?HIV Medicine
Source: Medscape Hiv-Aids Headlines - August 14, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Co-medications and drug-drug interactions in people living with HIV in Turkey in the era of integrase inhibitors.
CONCLUSION: Results suggested the need for attention about co-medication in PLWH regardless of whether they are young or older. CNS drugs should be questioned more detailed in MSM, as well as CVS drugs in older HS patients. Elvitegravir/cobicistat is significantly associated with DDIs and switching to an unboosted INSTI should be considered in patients with multiple comorbidities. PMID: 32787762 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 11, 2020 Category: Infectious Diseases Authors: Yeşilbağ Z, Şengül Eİ, Şenoğlu S, Aydın ÖA, Karaosmanoğlu HK Tags: Curr HIV Res Source Type: research

Prevention of Mother-to-Child Transmission of HIV: Data Analysis Based on Pregnant Women Population from 2012 to 2018, in Nantong City, China.
CONCLUSIONS: Prenatal identification of HIV infection and timely administration of all preventive measures can completely block MTCT of HIV. The data indicate that more efforts must be taken to ensure that all pregnant women are tested for anti-HIV during pregnancy. For pregnant women who missed prenatal screening, a positive result in rapid anti-HIV test at delivery should be sufficient to take preventive measures to prevent MTCT of HIV. PMID: 32778030 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 9, 2020 Category: Infectious Diseases Authors: Lou H, Ge X, Xu B, Liu W, Zhou YH Tags: Curr HIV Res Source Type: research

Correlates of HIV-positive fathers' involvement in prevention of mother-to-child transmission programs in northern Nigeria.
CONCLUSION: The involvement of fathers in HIV PMTCT programs was low and predicted by paternal education, HIVpositive child, duration of antiretroviral treatment, disclosure to partner, consistent condom use, and level of PMTCT knowledge. Our findings will inform the development of policies to increase male partner involvement in PMTCT in Nigeria. PMID: 32778029 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 9, 2020 Category: Infectious Diseases Authors: Iliyasu Z, Galadanci HS, Muhammad B, Yadudu FZ, Kwaku AA, Salihu HM, Aliyu MH Tags: Curr HIV Res Source Type: research

Spatio-temporal distribution of meningitis in HIV patients in Northern Egypt (2000-2018).
CONCLUSION: Despite the availability of cART, meningitis particularly cryptococcal is common in HIV/AIDS population in Egypt. Continued efforts are desperately needed to improve outcomes of HIV-infected patients. PMID: 32778028 [PubMed - as supplied by publisher]
Source: Current HIV Research - August 9, 2020 Category: Infectious Diseases Authors: Abd El-Wahab EW, Hegazy Y, Farrag T, Metwally M Tags: Curr HIV Res Source Type: research

Helpfulness of the EACS Cognitive Screening Questions in HIV Helpfulness of the EACS Cognitive Screening Questions in HIV
Are the EACS screening questions an effective tool for assessing neurocognitive impairment in patients with HIV?HIV Medicine
Source: Medscape Hiv-Aids Headlines - August 7, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

HCV Co-Infection and Treatment and CKD Risk in HIV HCV Co-Infection and Treatment and CKD Risk in HIV
Might HCV treatment have a role in mitigating the risk for developing chronic kidney disease among HIV/HCV co-infected individuals?AIDS
Source: Medscape Hiv-Aids Headlines - August 5, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Updated Direct Costs of Medical Care for HIV From 2006-2017 Updated Direct Costs of Medical Care for HIV From 2006-2017
How have costs for HIV care evolved and changed in recent years? A new study provides an update.HIV Medicine
Source: Medscape Hiv-Aids Headlines - July 31, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

HIV Testing and PrEP Use Among Transgender People HIV Testing and PrEP Use Among Transgender People
HIV testing and pre-exposure prophylaxis are both effective methods of preventing the transmission of HIV, but how likely are transgender people to engage in these strategies?JAIDS: Journal of Acquired Immune Deficiency Syndromes
Source: Medscape Hiv-Aids Headlines - July 30, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Sleep Apnea Risk May Be Elevated in Men With HIV Sleep Apnea Risk May Be Elevated in Men With HIV
Risk of sleep apnea may be elevated in men with HIV, a new study suggests.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - July 29, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

RBP4, a Potential Biomarker of Frailty in HIV RBP4, a Potential Biomarker of Frailty in HIV
Might higher levels of retinol-binding protein 4 predict frailty in HIV-infected patients?HIV Medicine
Source: Medscape Hiv-Aids Headlines - July 24, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

FGF21 and its Relationship with Inflammatory and Metabolic Parameters in HIV Patients after Antiretroviral Treatment.
CONCLUSIONS: The decrease of serum FGF21 levels due to ART is associated with the alteration in lipid profile and an increased risk for cardiovascular diseases. These variations are predictors of inflammatory status in HIV patients using antiretroviral therapy. PMID: 32684151 [PubMed - as supplied by publisher]
Source: Current HIV Research - July 18, 2020 Category: Infectious Diseases Authors: Ruiz-Padilla AJ, Ruiz-Noa Y, Del Rocio Ibarra-Reynoso L, Lazode-la-Vega-Monroy ML, Alonso-Castro AJ, Sánchez-Barajas M, Alvarez-Alvarez RM, Del Carmen Preciado-Puga M Tags: Curr HIV Res Source Type: research

Integrated Testing and Care for Hepatitis, HIV, STIs and TB Integrated Testing and Care for Hepatitis, HIV, STIs and TB
Policy changes are urgently needed to address the challenges of timely and integrated testing and care for these diseases.HIV Medicine
Source: Medscape Hiv-Aids Headlines - July 17, 2020 Category: Infectious Diseases Tags: HIV/AIDS Journal Article Source Type: news

Easy Access to PrEP Reduces Rates of HIV Acquisition Easy Access to PrEP Reduces Rates of HIV Acquisition
A community-based approach to the prescription of pre-exposure prophylaxis (PrEP) in East Africa led to a significant decrease in new cases of HIV, and could work in the United States.Medscape Medical News
Source: Medscape Hiv-Aids Headlines - July 14, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

HIV Infection May Impact Sensitivity of Rapid Diagnostic Tests for HCV HIV Infection May Impact Sensitivity of Rapid Diagnostic Tests for HCV
Hepatitis C virus rapid diagnostic tests had variable sensitivity in patients with HIV, in a multinational retrospective study.Reuters Health Information
Source: Medscape Hiv-Aids Headlines - July 14, 2020 Category: Infectious Diseases Tags: HIV/AIDS News Source Type: news

Prevalence of COVID-19-like symptoms among people living with HIV, and using antiretroviral therapy for prevention and treatment.
CONCLUSIONS: It appears that existing infection with HIV or receiving ART might reduce the susceptibility to the infection with SARS-CoV-2 or decrease the severity of the infection acquired. Further research is needed to understand causal mechanisms. PMID: 32652912 [PubMed - as supplied by publisher]
Source: Current HIV Research - July 11, 2020 Category: Infectious Diseases Authors: SeyedAlinaghi S, Ghadimi M, Hajiabdolbaghi M, Rasoolinejad M, Abbasian L, Nezhad MH, Manshadi SD, Ghadimi F, Ahmadinejad Z Tags: Curr HIV Res Source Type: research

The Effect of Antiretroviral Therapy on IL-6, IL-1 β, TNF-α, IFN-γ Levels and their Relationship with HIV-RNA and CD4+ T Cells in HIV Patients.
CONCLUSIONS: Althugh serum concentrations of IL-6, IL-1β and TNF-a showed significant decrease after ART, they were still significantly higher than the controls. IFN-γ responded differently to ART compared to the other cytokines, indicating that it may play a distinct and important role in the pathogenesis of HIV infection. PMID: 32652911 [PubMed - as supplied by publisher]
Source: Current HIV Research - July 11, 2020 Category: Infectious Diseases Authors: Okay G, Koc MM, Guler EM, Yabaci A, Kocyigit A, Akkoyunlu Y Tags: Curr HIV Res Source Type: research