A first look at interstitial fluid flow in the brain
(American Institute of Physics) Past research has shown a link between interstitial fluid flow and an increased invasion rate of glioblastoma cells, and biomedical researchers and electrical engineers recently developed a new method to measure and reconstruct interstitial fluid flow velocities in the brain. This method gives a first look at interstitial fluid flow dynamics in glioma models, and the technique can readily translate to clinical models already using contrast-enhanced MRI. The team describes their method in APL Bioengineering. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 3, 2018 Category: International Medicine & Public Health Source Type: news
MGMT Methylation a Survival Biomarker in High-Risk Low-Grade Gliomas?
These are the first data to highlight the prognostic value ofMGMTmethylation beyond theIDH1/2 mutation status test currently used to help predict glioma patient survival outcomes. (Source: CancerNetwork)
Source: CancerNetwork - June 29, 2018 Category: Cancer & Oncology Authors: John Schieszer Source Type: news
Delivery Device Sends'Chemosurgery' to Brainstem Tumor Delivery Device Sends'Chemosurgery' to Brainstem Tumor
Convection-enhanced drug infusion achieves high local concentrations with little or no systemic exposure in children with inoperable pontine glioma.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - June 29, 2018 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Living With Cancer: Understanding glioma
Glioma? Glioma is one of the most common types of primary brain tumors and can occur in the brain and spinal cord. Gliomas begin in the glial cells ? the gluey supportive cells that surround nerve cells and help them function. A glioma can affect your brain function and be life-threatening, depending on its location [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - June 29, 2018 Category: Databases & Libraries Source Type: news
Men and women have different genetic risk factors for developing brain cancer
(Case Western Reserve University) A team from Case Western Reserve University School of Medicine, together with an international consortium of researchers, have discovered that men and women have different genetic risk factors for developing glioma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 28, 2018 Category: Cancer & Oncology Source Type: news
Novel nuclear medicine approach shows promise for treating wide array of cancerous tumors
(Society of Nuclear Medicine and Molecular Imaging) A novel nuclear medicine approach is showing great promise for precision treatment of solid tumors in many types of cancer--including lung, breast, pancreas and ovarian in adults and glioma, neuroblastoma and sarcoma in children. The research was presented today at the SNMMI 2018 Annual Meeting, June 23-26 in Philadelphia. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 25, 2018 Category: Cancer & Oncology Source Type: news
Girl, 3, with an inoperable brain tumour may now survive
Edie Molyneux, from Tranmere, Wirral, was expected to die young because of the rare mass on her brain, known as a diffuse intrinsic pontine glioma (DIPG). (Source: the Mail online | Health)
Source: the Mail online | Health - June 20, 2018 Category: Consumer Health News Source Type: news
New Fibrillarin Antibody
Potent Nucleoli MarkerGiven the importance ofNucleus and Related Markers to all branches of cell/molecular biology, we are dedicated to having the best.We have just added a newFibrillarin Antibody.Images: Immunofluorescent analysis of (A) C6 rat glioma cells and (B) Human embryonic kidney cells stained with mouse mAb to fibrillarin, MO22169, dilution 1:1,000 in red, in both cases costained with chicken pAb to vimentin, CPCA-Vim, dilution 1:10,000 in green. The blue is DAPI staining of nuclear DNA.Nop1p/Fibrillarin was originally identified as a nucleolar protein of bakers yeast, Saccharomyces cerevisiae (accession P15646)....
Source: Neuromics - June 4, 2018 Category: Neuroscience Tags: Fibrillarin Antibody Nuclear Staining Nucleoli Source Type: news
New study points to a potential 'Achilles heel' in brain cancer
(Virginia Commonwealth University) Scientists at Virginia Commonwealth University believe they have uncovered an 'Achilles heel' of glioblastoma multiforme (GBM), the most common and deadly form of brain cancer. Their study published this week in the Proceedings of the National Academy of Sciences details how a mechanism that protects glioma stem cells can potentially be exploited to develop new and more effective treatments for GBM. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 4, 2018 Category: Cancer & Oncology Source Type: news
MR spectroscopy imaging reveals effects of targeted treatment of mutant IDH1 gliomas
(Massachusetts General Hospital) Using a novel imaging method, a Massachusetts General Hospital research team is investigating the mechanisms behind a potential targeted treatment for a subtype of the deadly brains tumors called gliomas. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 18, 2018 Category: International Medicine & Public Health Source Type: news
Operating on brain gliomas by detecting the 'glow'
(St. Joseph's Hospital and Medical Center) Research by Barrow Neurological Institute physicians and University of Washington scientists on novel imaging technology for malignant brain tumors was published in the April issue of World Neurosurgery. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 9, 2018 Category: Cancer & Oncology Source Type: news
Persistence pays off in discovery that could lead to improved treatment and survivability of patient
(Huntsman Cancer Institute) Gliomas are the most common type of central nervous system cancer but how these tumors develop is not fully understood. Sheri Holmen, PhD a researcher at Huntsman Cancer Institute (HCI) and professor of surgery at the University of Utah just published the results of her research on gliomas in Cell Reports. The work is focused on a mutated gene that is a critical piece of the puzzle for glioma development, according to Holmen's work. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 1, 2018 Category: International Medicine & Public Health Source Type: news
Glioma subtypes determine how the dangerous tumors spread, evade anti-angiogenic treatment
(Massachusetts General Hospital) A multi-institutional research team led by investigators at Massachusetts General Hospital and the University of California San Francisco has identified a new mechanism by which the dangerous brain tumors called gliomas develop resistance to anti-angiogenic treatment. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 27, 2018 Category: Cancer & Oncology Source Type: news
Tocagen and ApolloBio Enter License Agreement to Develop and Commercialize Toca 511 and Toca FC in the Greater China Region
Tocagen eligible to receive up to $127 million in upfront payment, development and commercial milestones, plus additional double-digit tiered sales royalties
Upfront and near-term development milestones payments total up to $20 million
SAN DIEGO and ... Biopharmaceuticals, Oncology, Licensing Tocagen, ApolloBio, immunotherapy, high grade glioma (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 19, 2018 Category: Pharmaceuticals Source Type: news
The cellular composition of H3K27M gliomas
(Source: ScienceNOW)
Source: ScienceNOW - April 19, 2018 Category: Science Authors: Zahn, L. M. Tags: Genetics, Medicine, Diseases twis Source Type: news
