Long Covid trials aim to clear lingering virus —and help patients in need
One Monday morning last September, Shelley Hayden pulled into a parking spot in an underground garage at the University of California San Francisco (UCSF). She switched off the ignition, pushed the red record button on her cellphone, and gazed into the camera. “The time has come,” said Hayden, long dark-blond hair framing her blue eyes. “Here we are, I’m actually getting to do something.”
More than 3 years earlier, in the summer of 2020, Hayden had come down with COVID-19 while visiting family in Colorado. Since then she’s been plagued by the disease’s cruel sequel, Long Covid, whose symptoms include ov...
Source: ScienceNOW - April 11, 2024 Category: Science Source Type: news
Insights into epileptogenesis from post-traumatic epilepsy - Pease M, Gupta K, Mosh é SL, Correa DJ, Galanopoulou AS, Okonkwo DO, Gonzalez-Martinez J, Shutter L, Diaz-Arrastia R, Castellano JF.
Post-traumatic epilepsy (PTE) accounts for 5% of all epilepsies. The incidence of PTE after traumatic brain injury (TBI) depends on the severity of injury, approaching one in three in groups with the most severe injuries. The repeated seizures that charact... (Source: SafetyLit)
Source: SafetyLit - April 5, 2024 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
French-led team unveils 11.7 tesla MRI scans of human brain
A research group based in Saclay, near Paris, has taken the wraps off what it claims are the world's first MRI scans of the human brain in vivo taken at a field strength of 11.7 tesla. President Emmanuel Macron has congratulated the researchers on social media.
"The first images surpassed our expectations, giving after just four minutes, mind-blowing brain images without any artifacts, with superb tissue contrast and resolution, which represents a volume equivalent to a few thousand neurons," Denis Le Bihan, PhD, founding director of the NeuroSpin research facility and founder of Iseult Project of the French Alternative E...
Source: AuntMinnie.com Headlines - April 4, 2024 Category: Radiology Authors: Philip Ward Tags: MRI Source Type: news
Psychiatric and behavioral concerns of perampanel with concomitant levetiracetam in children with epilepsy - Kim JS, Kim WS, Sung WY, Woo H.
PURPOSE: Perampanel (PER) is expanding the therapeutic scope for pediatric epilepsy owing to its efficacy and favorable safety profile. However, concerns about psychiatric and behavioral adverse events (PBAEs) in combination therapy with levetiracetam (LEV... (Source: SafetyLit)
Source: SafetyLit - March 30, 2024 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
How Saudi investors found their way into an East Bay biotech targeting epilepsy
Hevolution ’s first Bay Area investment, in a Berkeley company, could help the company target Alzheimer's, Parkinson's and other neurodegenerative diseases. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 28, 2024 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news
Stoke Therapeutics plans $75M public offering on heels of Dravet trial results
The Bedford-based biotech ’s are trading at the highest point since October 2022 after it announced promising results from an early-stage trial of its drug for a rare, debilitating form of epilepsy that affects children. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 27, 2024 Category: Pharmaceuticals Authors: Hannah Green Source Type: news
Trial results for Dravet drug spurs stock surge at Bedford biotech
Stoke Therapeutics, which develops RNA-altering drugs for rare diseases, announced what it called “landmark” results from an early-stage trial of a drug for a rare, debilitating form of epilepsy that affects children. (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - March 26, 2024 Category: Pharmaceuticals Authors: Don Seiffert Source Type: news
Auburn installs Siemens Magnetom 7T MRI scanner
Auburn University has installed Siemens' Magnetom 7T MRI scanner in its College of Engineering.
The scanner features dedicated radiofrequency sodium imaging coils and parallel transmit technology and will be used for brain and knee imaging, with a clinical focus on better understanding epilepsy, multiple sclerosis, and other disorders.Siemens' Magnetom 7T MRI scanner.PR Newswire
Projects currently underway that will use the scanner include research exploring post-traumatic stress disorder biomarkers in senior adults via spectroscopy, comparing brain connectivity between healthy populations with mental illness with a focu...
Source: AuntMinnie.com Headlines - March 26, 2024 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Source Type: news
The fight to cure South Sudan ’s mysterious neurological disorder
Nodding syndrome is a distressing disease that stunts growth, harms brains and sparks convulsions. Though its cause is still unknown, there is now hope that epilepsy drugs can help afflicted childrenThe other children move away, frightened, when the convulsions start. Tabo takes a long, guttural breath before slumping on to the ground unconscious, her entire body shaking. The 17-year-old ’s mother, Penina Monyo Gulu Biro, gently holds the girl while the attack lasts.A minute or two later, Tabo (pictured above) sits up again, tears rolling down her cheeks. “She cries because she’s sad to be like this,” says Biro.An ...
Source: Guardian Unlimited Science - March 25, 2024 Category: Science Authors: Florence Miettaux in Mvolo and Maridi Tags: Global development Global health South Sudan Africa World news Rivers Environment Infectious diseases Medical research Science Children Society Blindness and visual impairment Disability Source Type: news
'I had an epileptic seizure and fell down a mountain - this is how it changed my life'
An epileptic seizure caused Maria Domsova to fall down a mountain, resulting in a dramatic emergency rescue (Source: Daily Express - Health)
Source: Daily Express - Health - March 23, 2024 Category: Consumer Health News Source Type: news
Posttraumatic epilepsy in chronic disorders of consciousness due to severe traumatic brain injury after traffic accidents - Yasuda S, Yano H, Ikegame Y, Kumagai M, Iwama T, Shinoda J, Izumo T.
PURPOSE: To evaluate the clinical state of posttraumatic epilepsy (PTE) in patients with chronic disorders of consciousness (CDC) due to severe traumatic brain injury (STBI) after traffic accidents and clarify the risk factors for seizure occurrence in suc... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Brain network entropy, depression, and quality of life in people with traumatic brain injury and seizure disorders - Allendorfer JB, Nenert R, Goodman AM, Kakulamarri P, Correia S, Philip NS, LaFrance WCJ, Szaflarski JP.
OBJECTIVE: Traumatic brain injury (TBI) often precedes the onset of epileptic (ES) or psychogenic nonepileptic seizures (PNES) with depression being a common comorbidity. The relationship between depression severity and quality of life (QOL) may be related... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Clearance for driving in genetic generalized epilepsy - Desai J, Sadrieh K, Singh E.
A key aspect of management of genetic generalized epilepsy involves assessing seizure control and deciding suitability for driving motor vehicles. We surveyed child neurologists and pediatric epileptologists on key questions that practitioners should ask p... (Source: SafetyLit)
Source: SafetyLit - March 22, 2024 Category: International Medicine & Public Health Tags: Distraction, Fatigue, Chronobiology, Vigilance, Workload Source Type: news
Common Epilepsy, Migraine Drug Topiramate Won't Raise Odds for Autism in Offspring
THURSDAY, March 21, 2024 -- A common antiseizure drug used to treat epilepsy, migraines and bipolar disorder does not appear to increase the risk of autism for kids exposed to it in the womb, a new study says.
Topiramate does not contribute to any... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 21, 2024 Category: General Medicine Source Type: news
New Data Fuel Debate on Autism and Prenatal Topiramate Exposure
(MedPage Today) -- The incidence of autism spectrum disorder was higher among children exposed to topiramate in the second half of pregnancy than in the general population, but not relative to other children born to women with epilepsy, a study... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 20, 2024 Category: Neurology Source Type: news
