Paliperidone poisoning and measurable plasma concentrations 2.5  years after last administered dose: a case report - Nersesjan M, Wagner M, Dalhoff KP, Petersen TS, Bøgevig S, Horwitz H.
We report a poisoning with paliperidone palmitate, a once-monthly, long-acting injectable antipsychotic. The patient suffered from deep sedation and dystonia. She had been treated with extended release intramuscular paliperidone for several years and had r... (Source: SafetyLit)
Source: SafetyLit - March 11, 2024 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Evaluation of Global Dystonia Rating Scale as a predictor of unfavorable outcomes among acute antipsychotics poisoned patients - Sharif AF, Sobh ZK, Abdo SAEF, Alahmadi OM, Alharbi HA, Awaji MS, Alabdullatif FA, Baghlaf AM, Alanazi AF, Fayed MM.
Worldwide, acute antipsychotic poisoning results in high morbidities and mortalities. Though extrapyramidal syndromes are commonly associated, the extent of extrapyramidal syndromes in relation to the severity of antipsychotic poisoning has not been addres... (Source: SafetyLit)
Source: SafetyLit - February 16, 2024 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

UT Health San Antonio doctors among first to implant rechargeable deep brain stimulation device
New neurostimulator used by The University of Texas Health Science Center at San Antonio offers significant benefit for those with Parkinson's disease, dystonia, epilepsy and essential tremor conditions. SAN ANTONIO, Feb. 15, 2024 /PRNewswire-PRWeb/ -- Doctors at The University of Texas... (Source: PRWeb: Medical Pharmaceuticals)
Source: PRWeb: Medical Pharmaceuticals - February 15, 2024 Category: Pharmaceuticals Source Type: news

Oculogyric crisis due to aripiprazole ingestion as a suicide attempt: a case report - Bafarat A, Alaseeri B, Labban SA, Morya RE.
Oculogyric crisis (OGC) is a rare type of acute dystonia characterized by spasmodic upward deviation of the eyes lasting for a few minutes to several hours. It is commonly seen with the administration of first-generation antipsychotics and rarely reported ... (Source: SafetyLit)
Source: SafetyLit - December 11, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

FDA Approves First Therapeutic Indication for Revance ’s Daxxify (daxibotulinumtoxinA-lanm) for Injection for the Treatment of Cervical Dystonia
Provides Revance entry into the $2.5 billion U.S. therapeutic neuromodulator market.1 Approval expands the Daxxify® label to include efficacy data over the 52-week ASPEN repeat dose clinical study. Daxxify® for cervical dystonia is the... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - August 15, 2023 Category: Drugs & Pharmacology Source Type: news

Botulinum Toxin Daxxify Gets FDA Nod for Cervical Dystonia Botulinum Toxin Daxxify Gets FDA Nod for Cervical Dystonia
The FDA grants daxibotulinumtoxinA-lanm injection (Daxxify, Revance Therapeutics) a therapeutic indication for treatment of cervical dystonia in adults.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - August 15, 2023 Category: Neurology Tags: Neurology & Neurosurgery News Alert Source Type: news

Focal dystonia and the stress network: the role of stress vulnerability and adverse childhood experiences in the development of musician's dystonia - Alpheis S, Altenm üller E, Scholz DS.
Musician's dystonia is often described as a neurological disorder, resulting from reduced inhibition in the basal ganglia and the cerebellum and dysfunctional cortical plasticity. However, several studies over the last decades support the hypothesis that p... (Source: SafetyLit)
Source: SafetyLit - June 22, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Why Does He Rock His Body?
Discussion Stereotypies are “…patterned, repetitive, purposeless, involuntary movements that are also rhythmic and continual and tend to change little over time.” They occur at all times of the day, and can get worse with stress or heightened emotions including happiness. Stereotypies more often occur in children with developmental disabilities (up to 61%), sensory impairments (e.g. blindness) or social deprivation. They can be present more often in patients with autism (up to 88%). They can be seen in ~7% of normally developing children too. Their onset is before age 3 years and tend to improve over year...
Source: PediatricEducation.org - May 22, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Her Foot Looked Normal. What Was Causing the Excruciating Pain?
A few weeks after she twisted her ankle, the girl ’s foot kept getting worse. Her hand movements cued the doctor to a mysterious disease. (Source: NYT Health)
Source: NYT Health - February 7, 2023 Category: Consumer Health News Authors: Lisa Sanders, M.D. Tags: Ankles (Body Part) Dystonia Sports Injuries Genetics and Heredity Source Type: news

Up to 88% of fatty liver patients that develop cirrhosis report dystonia in ‘lower limbs'
Liver cirrhosis is responsible for the vast majority of fatty liver injuries in Western countries. (Source: Daily Express - Health)
Source: Daily Express - Health - January 30, 2023 Category: Consumer Health News Source Type: news

Video Clues Suggest Dystonia in Cerebral Palsy Video Clues Suggest Dystonia in Cerebral Palsy
Although a frequent complication of cerebral palsy, dystonia often goes undiagnosed; but a unique new video analysis has identified movement features that have the potential to simplify diagnosis.MDedge News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 20, 2022 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Oral self-mutilation in Lesch-Nyhan syndrome: a case report - Ferr ão J, Rodrigues Barros C, Figueiredo L, Fernandes A.
Lesch-Nyhan syndrome (LNS) is an inherited recessive X-related disorder caused by a deficiency of the purine salvage enzyme hypoxanthine-guanine phosphoribosyltransferase. It is characterized by dystonia and  compulsive self-mutilation, in particular, biti... (Source: SafetyLit)
Source: SafetyLit - September 19, 2022 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Casualty actor Derek Thompson on the 'murderous' condition he 'tried to ignore' - dystonia
LONG-RUNNING series Casualty began back in September 1986, with various characters coming and going along the way. One of the original characters, who has appeared in the drama series since its inception is Charlie Fairhead, played by Derek Thompson. As the only remaining member of the original cast, Thompson's character has been a part of the most memorable storylines. But the actor's most challenging moment was off-screen, when he was diagnosed with dystonia. (Source: Daily Express - Health)
Source: Daily Express - Health - May 17, 2022 Category: Consumer Health News Source Type: news

Influence of adverse childhood experiences and perfectionism on musician's dystonia: a case control study - Alpheis S, Altenm üller E, Scholz DS.
BACKGROUND: Musician's dystonia (MD) is a task-specific movement disorder characterized by muscle cramps and impaired voluntary motor-control whilst playing a musical instrument. Recent studies suggest an involvement of adverse childhood experiences (ACEs)... (Source: SafetyLit)
Source: SafetyLit - April 15, 2022 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Safer Way to Use Botox to Treat Challenging Dystonia Type? Safer Way to Use Botox to Treat Challenging Dystonia Type?
When treating oromandibular dystonia with botulinum toxin injection to the lateral pterygoid muscle, an intraoral approach is the safest way to avoid injury to the maxillary artery, new research suggests.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - October 5, 2021 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news