Study on exosomes for identifying bipolar disorder in early stage: A cross ‐sectional and validation study protocol
DiscussionExosome-derived microRNA and related proteins have potential in serving as a good medium for exploring mental disorders because it can pass through the blood-brain barrier bidirectionally and convey a large amount of information stably. Improving the early diagnosis of BD would help implement appropriate intervention strategy as early as possible and significantly reduce the burden of disease. (Source: Brain and Behavior)
Source: Brain and Behavior - April 20, 2024 Category: Neurology Authors: Yanqing Wu,
Yuchao Li,
Xuguang An,
Jiangong Li,
Chenghao Yang,
Yi Wang Tags: METHOD Source Type: research
One in Four People With Schizophrenia or Bipolar Have Multiple Physical Health Problems
Astudy inLancet Psychiatry reports that adults with schizophrenia or bipolar disorder are more than twice as likely as those without these disorders to have multiple physical health problems like heart disease or diabetes. Further, the presence of multiple physical problems was more common in adults with schizophrenia or bipolar disorder than the presence of multiple psychiatric disorders.“While health services and treatment guidelines often operate on the assumption that individuals have a single principal diagnosis, these results attest to the clinical complexity many people with severe mental illness face in relation ...
Source: Psychiatr News - April 19, 2024 Category: Psychiatry Tags: bipolar disorder chronic disease comorbidities Lancet Psychiatry physical health premature mortality schizophrenia Source Type: research
Surface charge density and induced currents by self-charging sliding drops
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Pravash Bista, Aaron D. Ratschow, Amy Z. Stetten, Hans-J ürgen Butt, Stefan A.L. Weber Sliding drops induce a bipolar current in subsurface electrodes beneath a hydrophobic substrate. We show how it depends on substrate properties and how it can be optimized for energy harvesting. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Soft Matter latest articles)
Source: RSC - Soft Matter latest articles - April 19, 2024 Category: Chemistry Authors: Pravash Bista Source Type: research
High Carrier Mobility and Promising Thermoelectric Module Performance of N ‐Type PbSe Crystals
Optimizing carrier concentration is crucial for thermoelectric materials. Previous studies suggest an ideal range from ~1019 to ~1021 cm−3 (blue line). Yet, grain boundaries in polycrystals hinder carrier mobility. The authors propose enhancing mobility through crystal growth and light-doping at lower concentrations (from ~1018 to 1019 cm−3) for potentially elevated ZT values (red line). AbstractThe scarcity of Te hampers the widespread use of Bi2Te3-based thermoelectric modules. Here, the thermoelectric module potential of PbSe is investigated by improving its carrier mobility. Initially, large PbSe crystals are gro...
Source: Small - April 19, 2024 Category: Nanotechnology Authors: Siqi Wang,
Yi Wen,
Yingcai Zhu,
Ziyuan Wang,
Dongrui Liu,
Junqing Zheng,
Shaoping Zhan,
Hongyao Xie,
Zhenhua Ge,
Xiang Gao,
Qian Cao,
Cheng Chang,
Li ‐Dong Zhao Tags: Research Article Source Type: research
Most People Experiencing Homelessness Have Mental Health Disorders, Study Finds
Sixty-seven percent of people experiencing homelessness worldwide have a mental health disorder, according to areport published yesterday inJAMA Psychiatry. Additionally, the prevalence of mental health disorders among this population appears to be on the rise.“The relationship between mental health disorders and homelessness is complex and bidirectional,” wrote Rebecca Barry, Ph.D., of the University of Calgary and colleagues. “[M]ental health disorders may lead to situations that result in homelessness, or homelessness may be a stressor contributi ng to the development or worsening of mental health disorder symptom...
Source: Psychiatr News - April 18, 2024 Category: Psychiatry Tags: antisocial personality disorder homeless JAMA Psychiatry mental health disorders meta-analysis North America Rebecca Barry schizophrenia substance use disorders systematic review University of Calgary Source Type: research
Demographics and clinical characteristics of patients of prescribing psychologists, psychiatrists, and primary care physicians
Am Psychol. 2024 Apr 18. doi: 10.1037/amp0001352. Online ahead of print.ABSTRACTTo describe the characteristics of patients receiving psychotropic medication from prescribing psychologists, psychiatrists, and primary care physicians. This descriptive study was conducted using private insurance claims of patients from New Mexico and Louisiana receiving psychotropic medications (anticonvulsants, antidepressants, antipsychotics, hypotensive agents, anxiolytics/sedatives/hypnotics, and stimulants) from 2004 to 2021 (N = 307,478). Patient characteristics were captured during the 6 months prior to their first psychotropic medica...
Source: The American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Authors: Phillip M Hughes Joshua D Niznik Robert E McGrath Casey R Tak Robert B Christian Betsy L Sleath Kathleen C Thomas Source Type: research
The association between schizophrenia and increased COVID-19 mortality in a cohort of over 2 million people in Brazil
CONCLUSIONS: Patients diagnosed with schizophrenia have a greater likelihood of COVID-19- related death than those without mental health conditions. These findings underscore the significant effect of serious mental disorders on COVID-19 mortality.PMID:38635950 | DOI:10.47626/1516-4446-2024-3540 (Source: Revista Brasileira de Psiquiatria)
Source: Revista Brasileira de Psiquiatria - April 18, 2024 Category: Psychiatry Authors: Fabr ício Emanuel Soares de Oliveira Samuel Trezena Daniella Reis Barbosa Martelli Maria Christina L Oliveira Enrico A Colosimo Herc ílio Martelli Eduardo Ara újo Oliveira Source Type: research
Comparative utility of omnipolar and bipolar electroanatomic mapping methods to detect and localize dual nodal substrate in patients with atrioventricular nodal reentrant tachycardia
ConclusionsOmnipolar vector pivot analysis represents an automated, annotation-independent qualitative technique that is sensitive and specific for AVNRT substrate and co-localizes with successful SPM sites. Bipolar voltage quantitatively describes SP anisotropy better than omnipolar voltage, and the addition of peak frequency signal analysis further optimizes the selection of SPM sites.Graphical abstract (Source: Journal of Interventional Cardiac Electrophysiology)
Source: Journal of Interventional Cardiac Electrophysiology - April 18, 2024 Category: Cardiology Source Type: research
A bibliometric and visual analysis of cognitive function in bipolar disorder from 2012 to 2022
Bipolar disorder (BD) is a chronic psychiatric disorder that combines hypomania or mania and depression. The study aims to investigate the research areas associated with cognitive function in bipolar disorder ... (Source: Annals of General Psychiatry)
Source: Annals of General Psychiatry - April 18, 2024 Category: Psychiatry Authors: Xiaohong Cui, Tailian Xue, Zhiyong Zhang, Hong Yang and Yan Ren Tags: Review Source Type: research
A technique for reconstruction of a giant extracranial internal carotid artery aneurysm: A technical note
CONCLUSION: The selection of a strategy based on intraoperative findings and low-power bipolar cutting is important for the treatment of extracranial carotid artery aneurysms to preserve cranial nerves.PMID:38628507 | PMC:PMC11021075 | DOI:10.25259/SNI_11_2024 (Source: Surgical Neurology International)
Source: Surgical Neurology International - April 17, 2024 Category: Neurosurgery Authors: Atsushi Hashio Hiroki Sato Milan Lepi ć Kaima Suzuki Tsugumi Satoh Shin Nemoto Seiji Kuribara Yuhei Ito Shun Suzuki Ichi Lee Akio Teranishi Taro Yanagawa Toshiki Ikeda Hidetoshi Ooigawa Hiroki Kurita Source Type: research
GSE263713 Fibroblasts as an in vitro model of circadian genetic and genomic studies: A temporal analysis (RNA-Seq)
In this study, we characterize the biological pathways that are activated in this in vitro circadian model, evaluating the relevance of these processes in the context of the genetic architecture of BD and other disorders, highlighting its limitations and future applications for circadian genomic studies (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
GSE263711 Fibroblasts as an in vitro model of circadian genetic and genomic studies: A temporal analysis (ATAC-Seq)
In this study, we characterize the biological pathways that are activated in this in vitro circadian model, evaluating the relevance of these processes in the context of the genetic architecture of BD and other disorders, highlighting its limitations and future applications for circadian genomic studies (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Genome binding/occupancy profiling by high throughput sequencing Homo sapiens Source Type: research
Extreme —Super obesity and panniculectomy: bipolar radiofrequency scalpel assisted surgery as a valuable option for the most challenging cases
ConclusionsBRS assisted panniculectomy with minimal undermining is a valuable option for patients with extreme or super obesity. At the time of dissection, minimizing undermining and using BRS could make the operation safer and therefore extendable to a larger cohort of patients.Level of evidence: Level IV, Therapeutic; Risk/Prognostic. (Source: European Journal of Plastic Surgery)
Source: European Journal of Plastic Surgery - April 17, 2024 Category: Cosmetic Surgery Source Type: research
Association Between Cortical Thickness or Surface Area and Divergent Thinking in Patients with Bipolar Disorder
CONCLUSION: The findings indicate that divergent thinking involves cerebral structures for executive control, mental imagery, and visual processing in patients with BD, and the right prefrontal cortex might be the most crucial of these structures.PMID:38623725 | DOI:10.1017/neu.2024.17 (Source: Acta Neuropsychiatrica)
Source: Acta Neuropsychiatrica - April 16, 2024 Category: Psychiatry Authors: Pei-Chi Tu Wan-Chen Chang Yi-Hsuan Kuan Mu-Hong Chen Tung-Ping Su Source Type: research
